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Clinical trials for depression

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   43861   clinical trials with a EudraCT protocol, of which   7284   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    46 result(s) found for: depression. Displaying page 1 of 3.
    1  2  3  Next»
    EudraCT Number: 2008-001829-33 Sponsor Protocol Number: F1J-US-HMFA Start Date*: 2008-09-15
    Sponsor Name:Eli Lilly and Company
    Full Title: Duloxetine Versus Placebo in the Long-Term Treatment of Patients with Late-Life Major Depression
    Medical condition: Major Depressive Disorder in elderly patients
    Disease: Version SOC Term Classification Code Term Level
    9.1 10012378 Depression LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-004984-31 Sponsor Protocol Number: DR180133 Start Date*: 2021-04-21
    Sponsor Name:CHRU TOURS
    Full Title: Nitrous Oxide in Resistant Depression in Elderly Subjects: A Randomized, Double-blind, Comparator Trial
    Medical condition: Resistant Depression in the Elderly Subject
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-004457-20 Sponsor Protocol Number: P051071 Start Date*: 2008-07-04
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title: Evaluation de l'action neuroréparatrice fonctionnelle et morphologique du traitement antidepresseur au cours de la rémission clinique dans la dépression recurrente.
    Medical condition: Dépression récurrente
    Disease: Version SOC Term Classification Code Term Level
    8.1 10025454 Dépression récurrente PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-003816-38 Sponsor Protocol Number: PHRC-N/2017-FJ-01 Start Date*: 2020-11-09
    Sponsor Name:CHU DE NIMES
    Full Title: Add-on buprenorphine at analgesic doses for the treatment of severe suicidal ideas during a major depressive episode
    Medical condition: Treatment of severe suicidal ideas in patients suffers from a current major depressive episode
    Disease: Version SOC Term Classification Code Term Level
    23.0 100000004873 10083288 Clinical depression LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-002114-40 Sponsor Protocol Number: APHP200527 Start Date*: 2020-07-30
    Sponsor Name:Assistance Publique - Hôpitaux de Paris
    Full Title: Nintedanib for the treatment of SARS-Cov-2 induced pulmonary fibrosis
    Medical condition: Patients 2 to 6 months after Covid-19 acute pneumonia
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2022-002385-32 Sponsor Protocol Number: APHP211057 Start Date*: 2022-08-31
    Sponsor Name:Assistance Publique – Hôpitaux de Paris (AP-HP)
    Full Title: Immediate versus delayed treatment with azathioprine or rituximab in anti-myelin oligodendrocytes glycoprotein (anti-MOG) antibodies associated acute demyelinating syndromes in children: a randomiz...
    Medical condition: myelin oligodendrocytes glycoprotein antibody associated diseases (MOGAD)
    Disease:
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-004740-30 Sponsor Protocol Number: PHRCN2018 Start Date*: 2021-09-15
    Sponsor Name:Centre Hospitalier Le Vinatier
    Full Title: Cannabidiol for reducing drinking in alcohol use disorder and modifying the effects of alcohol on the brain and the liver: a phase 2 clinical trial.
    Medical condition: CARAMEL is an exploratory phase-2 study conducted in subjects with AUD (alcohol use disorder) and current heavy drinking level, aiming to confirm the different properties of CBD observed in animal ...
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004873 10001590 Alcohol addiction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-001371-24 Sponsor Protocol Number: 6621 Start Date*: 2019-01-08
    Sponsor Name:Hôpitaux Universitaires de Strasbourg
    Full Title: Prospective, randomised, placebo-controlled study of polyvalent intravenous immunoglobulins for the treatment of primary Sjögren's syndrome associated painful sensory neuropathies
    Medical condition: Primary Sjögren's syndrome associated painful sensory neuropathies
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-002159-25 Sponsor Protocol Number: CSET 2008/1388 Start Date*: 2008-09-24
    Sponsor Name:Institut Gustave Roussy
    Full Title: Etude randomisée, en double aveugle, contre placebo, de l’Efficacité de l’ Escitalopram dans le traitement de la détresse émotionnelle des sujets atteints de cancer ORL en cours de traitement
    Medical condition: détresse émotionnelle des sujets atteints de cancer ORL
    Disease: Version SOC Term Classification Code Term Level
    9.1 10049119 Emotional distress LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-004802-70 Sponsor Protocol Number: APHP200491 Start Date*: 2021-08-03
    Sponsor Name:Assistance Publique – Hôpitaux de Paris
    Full Title: Impact of post-ARDS COVID sedation on late neuroinflammation
    Medical condition: All patients who have developed and survived ARDS linked to COVID-19 infection, admitted to intensive care units, meeting the study's inclusion criteria may be included in this research.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2022-000174-25 Sponsor Protocol Number: 101090401IN Start Date*: 2023-03-17
    Sponsor Name:SANTEN INCORPORATED
    Full Title: A Phase IIa, Randomized, Double-Masked, Placebo-Controlled, Parallel-Group, Multicenter Study Assessing the Efficacy and Safety of STN1010904 Ophthalmic Suspension 0.03% and 0.1% Compared with Vehi...
    Medical condition: Fuchs Endothelial Corneal Dystrophy (FECD)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004850 10014823 Endothelial corneal dystrophy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-001964-11 Sponsor Protocol Number: 2019/0411/HP Start Date*: 2021-12-17
    Sponsor Name:CHU de Rouen
    Full Title: Randomized double blind controlled trial comparing the safety and efficacy of apremilast versus placebo in severe forms of recurrent aphthous stomatitis
    Medical condition: Patients with severe forms of Recurrent Aphthous Stomatitis (RAS)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004856 10045372 Ulcers aphthous oral LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-014056-30 Sponsor Protocol Number: AOI 2009 - Jalenques Start Date*: 2009-10-07
    Sponsor Name:CHU Clermont-Ferrand
    Full Title: Reconnaissance des expressons faciales émotionnelles chez les patients présentant un épisode dépressif magnétique transcranienne répétée du cortex préfrontal dorsolatéral droit à basse fréquence et...
    Medical condition: depression
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-003930-10 Sponsor Protocol Number: KEKU1 Start Date*: 2018-01-12
    Sponsor Name:Recherche et enseignement en douleur, anesthesie reanimation
    Full Title: KETAMINE'S EFFICIENCY IN THE TREATMENT OF CHRONIC PAIN WITH INFLAMMATORY COMPONENT: EXPLORING THE KYNURENIN PATHWAYS. A controlled, placebo-controlled, double-blind trial.
    Medical condition: The population selected is a spinal cord injury population with central neuropathic pain at the lesional or sub-lesion level, chronically (for more than three months) Adult, spinal cord injury (SCI...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-001288-18 Sponsor Protocol Number: 16-API-01 Start Date*: 2019-01-08
    Sponsor Name:CHU de Nice
    Full Title: ASIC channels and migraine disorders - Proof of concept study on the efficacy of Amiloride in prophylaxis of Migraine with Aura - APAM study
    Medical condition: Migraine with aura
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029205 - Nervous system disorders 10027607 Migraine with aura PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-005081-19 Sponsor Protocol Number: 1 Start Date*: 2014-07-10
    Sponsor Name:HOSPICES CIVILS DELYON
    Full Title: Phase II study evaluating the efficacy of aflibercept for the treatment of idiopathic choroidal neovascularization in young subjects: the INTUITION study
    Medical condition: idiopathic choroidal neovascularization
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004853 10060837 Choroidal neovascularization LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-004835-19 Sponsor Protocol Number: 38RC16.015 Start Date*: 2017-07-20
    Sponsor Name:University Hospital Grenoble
    Full Title: Dexamethasone in Herpes Simplex Virus Encephalitis Open label Randomized Controlled Trial with an Observer-blinded evaluation at 6 months
    Medical condition: HSV encephalitis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000013665 10014590 Encephalitis herpes LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-001520-66 Sponsor Protocol Number: UC-0106/1607 Start Date*: 2018-06-13
    Sponsor Name:UNICANCER
    Full Title: Efficacy and safety of fentanyl citrate in painful access induced during diagnostic or therapeutic examinations in cancer patients
    Medical condition: Cancer patient
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-003321-14 Sponsor Protocol Number: P160942J Start Date*: 2018-08-03
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title: Prevention of DElirium with MELatonine in intensive care unit : prospective, multicenter, randomized, double-blind, placebo, multi-arm, multi-stage trial.
    Medical condition: patients in intensive care unit with invasive mechanical ventilation
    Disease: Version SOC Term Classification Code Term Level
    20.0 10037175 - Psychiatric disorders 10012218 Delirium PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-002499-14 Sponsor Protocol Number: PI2018_843_0051 Start Date*: 2021-05-26
    Sponsor Name:CHU Amiens-Picardie
    Full Title: RELYAGE (Relapse LYmphoma AGEd) : Assessment of survival and autonomy with Rituximab-Lenalidomide and Rituximab-Chemotherapy for elderly patients with relapsed diffuse large-B cell lymphoma : a ran...
    Medical condition: diffuse large B cell lymphoma
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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