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Clinical trials for Amblyopia

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44380   clinical trials with a EudraCT protocol, of which   7392   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    Query did not match any clinical trials.
    These are paediatric studies completed by 26 January 2007, in respect of products authorised in the Community (Article 45 of the Paediatric Regulation (EC) No 1901/2006).
    Note: Advanced search filters for country, trial phase, gender, rare disease, IMP with orphan designation in the indication and age ranges of in-utero, adult or elderly do not apply to these records.
    Study title: Penalization versus part-time occlusion and binocular outcome in treatment of strabismic amblyopia. Simons K, Gotzler KC, Vitale S. Ophthalmology. 1997 Dec;104(12):2156-60.
    Active substance: ATROPINE
    Study summary document link (including results): Penalization versus part-time occlusion and binocular outcom.pdf
    View full study record
    Document reference: 22022
    Study title: The course of moderate amblyopia treated with atropine in children: experience of the amblyopia treatment study. Pediatric Eye Disease Investigator Group. Am J Ophthalmol. 2003 Oct;136(4):630-9.
    Active substance: ATROPINE
    Study summary document link (including results): The course of moderate amblyopia treated with atropine.pdf
    View full study record
    Document reference: 22019
    Study title: The effect of amblyopia therapy on ocular alignment. Repka MX, Holmes JM, Melia BM, Beck RW, Gearinger MD, Tamkins SM, Wheeler DT; Pediatric Eye Disease Investigator Group. J AAPOS. 2005 Dec;9(6):542-5.
    Active substance: ATROPINE
    Study summary document link (including results): The effect of amblyopia therapy on ocular alignment.pdf
    View full study record
    Document reference: 22017
    Study title: The effect on refractive error of unilateral atropine as compared with patching for the treatment of amblyopia. Repka MX, Melia M, Eibschitz-Tsimhoni M, London R, Magoon E; Pediatric Eye Disease Investigator Group. J AAPOS. 2007 Jun;11(3):300-2.
    Active substance: ATROPINE
    Study summary document link (including results): The effect on refractive error of unilateral atropine.pdf
    View full study record
    Document reference: 22013
    Study title: Can retinoscopy be used to screen infants for amblyopia? A longitudinal study of refraction in the first year of life. Hopkisson B, Arnold P, Billingham B, McGarrigle M, Shribman S. Eye. 1992;6 ( Pt 6):607-9. Can retinoscopy be used to screen infants for amblyopia? A longitudinal study of refraction in the first year of life. Hopkisson B, Arnold P, Billingham B, McGarrigle M, Shribman S. Eye. 1992;6 ( Pt 6):607-9.
    Active substance: CYCLOPENTOLATE
    Study summary document link (including results): Can retinoscopy be used to screen infants for amblyopia.pdf
    View full study record
    Document reference: 24704
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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