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Clinical trials for Chemoprophylaxis

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44381   clinical trials with a EudraCT protocol, of which   7393   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    Query did not match any clinical trials.
    These are paediatric studies completed by 26 January 2007, in respect of products authorised in the Community (Article 45 of the Paediatric Regulation (EC) No 1901/2006).
    Note: Advanced search filters for country, trial phase, gender, rare disease, IMP with orphan designation in the indication and age ranges of in-utero, adult or elderly do not apply to these records.
    Study title: Corominas N, Gascon J, Mejias T, Caparros F, Quinto L, Codina C et al. Adverse effects associated with antimalarial chemoprophylaxis.[erratum appears in Med Clin (Barc) 1997 Oct 11;109(12):462]. Medicina Clinica 1997; 108(20):772-775.Corominas N, Gascon J, Mejias T, Caparros F, Quinto L, Codina C et al. Adverse effects associated with antimalarial chemoprophylaxis.[erratum appears in Med Clin (Barc) 1997 Oct 11;109(12):462]. Medicina Clinica 1997; 108(20):772-775.
    Active substance: CHLOROQUINE AND PROGUANIL
    Study summary document link (including results):
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    Document reference: 23967
    Study title: de SN, Marc E, Moulin F, Yera H, Dupouy-Camet J, Brunet F et al. Parasitemia in children with Plasmodium falciparum malaria recerving chemoprophylaxis. Pediatric Infectious Disease Journal 2003; 22(4):377-378.de SN, Marc E, Moulin F, Yera H, Dupouy-Camet J, Brunet F et al. Parasitemia in children with Plasmodium falciparum malaria recerving chemoprophylaxis. Pediatric Infectious Disease Journal 2003; 22(4):377-378.
    Active substance: CHLOROQUINE AND PROGUANIL
    Study summary document link (including results):
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    Document reference: 23961
    Study title: Minodier P, Kone-Paut I, Nassur A, Launay F, Jouve JL, Hassid S et al. Antimosquito precautions and medical chemoprophylaxis in French children with malaria. Journal of Travel Medicine 2003; 10(6):318-323.Minodier P, Kone-Paut I, Nassur A, Launay F, Jouve JL, Hassid S et al. Antimosquito precautions and medical chemoprophylaxis in French children with malaria. Journal of Travel Medicine 2003; 10(6):318-323.
    Active substance: CHLOROQUINE AND PROGUANIL
    Study summary document link (including results):
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    Document reference: 23964
    Study title: Minodier P, Noel G, Blanc P, Tsaregorodtseva N, Retornaz K, Garnier JM. Malaria chemoprophylaxis in traveling children. Archives de Pediatrie 2005; 12(1):53-58.Minodier P, Noel G, Blanc P, Tsaregorodtseva N, Retornaz K, Garnier JM. Malaria chemoprophylaxis in traveling children. Archives de Pediatrie 2005; 12(1):53-58.
    Active substance: CHLOROQUINE AND PROGUANIL
    Study summary document link (including results):
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    Document reference: 23957
    Study title: Tremolieres F. Chemoprophylaxis for malaria in special cases. Medecine et Maladies Infectieuses 1999; 29(Suppl 3):397S-405S.Tremolieres F. Chemoprophylaxis for malaria in special cases. Medecine et Maladies Infectieuses 1999; 29(Suppl 3):397S-405S.
    Active substance: CHLOROQUINE AND PROGUANIL
    Study summary document link (including results):
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    Document reference: 23966
    Study title: Wyler DJ. Drug-Therapy - Malaria chemoprophylaxis for the traveler. New(Negland-Journal-Of-Medicine 1993; 329(1):31-37.Wyler DJ. Drug-Therapy - Malaria chemoprophylaxis for the traveler. New(Negland-Journal-Of-Medicine 1993; 329(1):31-37.
    Active substance: CHLOROQUINE AND PROGUANIL
    Study summary document link (including results):
    View full study record
    Document reference: 23973
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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