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Clinical trials for Fenfluramine

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44381   clinical trials with a EudraCT protocol, of which   7393   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    Query did not match any clinical trials.
    These are paediatric studies completed by 26 January 2007, in respect of products authorised in the Community (Article 45 of the Paediatric Regulation (EC) No 1901/2006).
    Note: Advanced search filters for country, trial phase, gender, rare disease, IMP with orphan designation in the indication and age ranges of in-utero, adult or elderly do not apply to these records.
    Study title: AN 1978059362 19780101. TI Effects of fenfluramine and cyproheptadine on growth hormone secretion. AU Mazzi-C, Riva-L-P, Bernasconi-D. IN Div. Endocrinol. Med. Costituz., Osp. Gen. Prov. S. Antonio Abate, Gallarate, Italy. SO Annales d'Endocrinologie {ANN-ENDOCRINOL}, 1976, Vol/Iss/Pg. 37/5 (355-364). YR 1976.AN 1978059362 19780101. TI Effects of fenfluramine and cyproheptadine on growth hormone secretion. AU Mazzi-C, Riva-L-P, Bernasconi-D. IN Div. Endocrinol. Med. Costituz., Osp. Gen. Prov. S. Antonio Abate, Gallarate, Italy. SO Annales d'Endocrinologie {ANN-ENDOCRINOL}, 1976, Vol/Iss/Pg. 37/5 (355-364). YR 1976.
    Active substance: CYPROHEPTADINE
    Study summary document link (including results):
    View full study record
    Document reference: 25249
    Study title: Biol Psychiatry. 2000 Mar 15;47(6):540-7. A fenfluramine-activated FDG-PET study of borderline personality disorder. Soloff PH, Meltzer CC, Greer PJ, Constantine D, Kelly TM.
    Active substance: FLUDEOXYGLUCOSE
    Study summary document link (including results):
    View full study record
    Document reference: 28179
    Study title: Electrophysiological effects of fenfluramine or combined vitamin B6 and magnesium on children with autistic behaviour - J. Martineau et al. - 1989 (Developmental Medicine and Child Neurology vol 31) - Publication in MAGNE-B6 Magnesium - pyridoxine Tablet & Oral Solution -Response to questions raised during the renewal process in Estonia -Raphaëlle Pivaty- 04/2004 -Electrophysiological effects of fenfluramine or combined vitamin B6 and magnesium on children with autistic behaviour - J. Martineau et al. - 1989 (Developmental Medicine and Child Neurology vol 31) - Publication in MAGNE-B6 Magnesium - pyridoxine Tablet & Oral Solution -Response to questions raised during the renewal process in Estonia -Raphaëlle Pivaty- 04/2004 -
    Active substance: MAGNESIUM LACTATE + MAGNESIUM PIDOLATE + PYRIDOXINE (VIT B6)
    Study summary document link (including results):
    View full study record
    Document reference: 31485
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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