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Clinical trials for General anesthesia

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44339   clinical trials with a EudraCT protocol, of which   7369   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    Query did not match any clinical trials.
    These are paediatric studies completed by 26 January 2007, in respect of products authorised in the Community (Article 45 of the Paediatric Regulation (EC) No 1901/2006).
    Note: Advanced search filters for country, trial phase, gender, rare disease, IMP with orphan designation in the indication and age ranges of in-utero, adult or elderly do not apply to these records.
    Study title: Open label pharmacokinetic and safety evaluation of single iv dose (1,2mg/kg) of dolasetron mesylate in children undergoing elective and uncomplicated surgery under general anesthesia - Howard - 9 February 1995
    Active substance: DOLASETRON
    Study summary document link (including results):
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    Document reference: 26297
    Study title: Open label pharmacokinetic and safety evaluation of single oral dose (1,2mg/kg) of dolasetron mesylate in children undergoing elective and uncomplicated surgery under general anesthesia - Keung - 9 February 1995
    Active substance: DOLASETRON
    Study summary document link (including results):
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    Document reference: 26298
    Study title: Oral transmucosal fentanyl pretreatment for outpatient general anesthesia; J Anal Toxicol, 2006, 30(8): 603-610
    Active substance: FENTANYL
    Study summary document link (including results):
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    Document reference: 27156
    Study title: The pharmacokinetics of the intravenous formulation of fentanyl citrate administered orally in children undergoing general anesthesia; Anesthesia and Analgesia 2004, 99(5): 1347-51
    Active substance: FENTANYL
    Study summary document link (including results):
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    Document reference: 27185
    Study title: Study of the efficacy and safety of Ro 15-1788 in reversing the central effects of flunitrazepam used to induce and maintain general anesthesia
    Active substance: FLUNITRAZEPAM
    Study summary document link (including results):
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    Document reference: 28239
    Study title: To determine wether a modified propofol preparation shows any effect on the incidence of injection pain in children undergoing elective surgery under general anesthesia.
    Active substance: PROPOFOL
    Study summary document link (including results): BBMDE-0312.xls
    View full study record
    Document reference: 47082
    Study title: A comparative evaluation of Diprivan (propofol) versus standard anesthetic techniques when administered for the induction and maintenance of general anesthesia in pediatric patients undergoing surgical procedures of one hour or greater duration
    Active substance: PROPOFOL
    Study summary document link (including results):
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    Document reference: 46124
    Study title: A comparative evaluation of Diprivan /Diprivan N20 versus thiopental/halothane/N20 versus Diprivan/Diprivan when administered for the induction and maintenance of general anesthesia in pedaitric patients undergoing general surgical procedures of one hour or greater duration
    Active substance: PROPOFOL
    Study summary document link (including results):
    View full study record
    Document reference: 46125
    Study title: An open-label, multi-center, phase IV study to evaluate the efficacy and safety profiles of sevoflurane in pediatric subjects of different ages undergoing inpatient surgery with general anesthesia
    Active substance: SEVOFLURANE
    Study summary document link (including results): Sevoflurane-CHIN-05-001.pdf
    View full study record
    Document reference: 42152
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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