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Clinical trials for Holin

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44343   clinical trials with a EudraCT protocol, of which   7372   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    Query did not match any clinical trials.
    These are paediatric studies completed by 26 January 2007, in respect of products authorised in the Community (Article 45 of the Paediatric Regulation (EC) No 1901/2006).
    Note: Advanced search filters for country, trial phase, gender, rare disease, IMP with orphan designation in the indication and age ranges of in-utero, adult or elderly do not apply to these records.
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    Study title: phase IV double-blind multicenter study comparing the antipyretic effectiveness of aspirin, acetaminophen, choline salicylate and placebo in febrile children.
    Active substance: ACETYL SALICYLIC ACID AND PARACETAMOL AND CHOLINE SALICYLATE
    Study summary document link (including results): acetylsalicylic acid_choline salicylate_paracetamol 118.pdf
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    Document reference: 47208
    Study title: LMD124245 - Belzarena SD. Nasal intubation in paediatric patients. Comparison between a combination of alfentanil and lidocaine versus succinylcholine [translation]. Revista Brasileira de Anestesiologia, 46 (5), p. 323-328, 1996.LMD124245 - Belzarena SD. Nasal intubation in paediatric patients. Comparison between a combination of alfentanil and lidocaine versus succinylcholine [translation]. Revista Brasileira de Anestesiologia, 46 (5), p. 323-328, 1996.
    Active substance: ALFENTANIL
    Study summary document link (including results): belzarenaengabstract_alfentanil.pdf
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    Document reference: 46369
    Study title: Meeroff M. Anticholinergics and antacid tablets versus cimetidine in the treatment of active duodenal ulcers. Curr Therapeut Research 1981, 29, 6, 866-873 Sievert W. Low-dose antacids and nonsteroidal anti-inflammatory drug-induced gastropathy in humans. J Clin Gastroenterol 1991, 13 (Suppl1), 145-148Meeroff M. Anticholinergics and antacid tablets versus cimetidine in the treatment of active duodenal ulcers. Curr Therapeut Research 1981, 29, 6, 866-873 Sievert W. Low-dose antacids and nonsteroidal anti-inflammatory drug-induced gastropathy in humans. J Clin Gastroenterol 1991, 13 (Suppl1), 145-148
    Active substance: ALUMINIUM HYDROXIDE AND MAGNESIUM HYDROXIDE
    Study summary document link (including results):
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    Document reference: 46466
    Study title: Characterization of asymptomatic methacholine airway hyperresponsiveness (MAHR) in children: budesonide or placebo Turbuhaler treated
    Active substance: BUDESONIDE
    Study summary document link (including results): 04-9203 Study Synopsis.pdf
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    Document reference: 22932
    Study title: A phase IV double-blind multicenter study comparing the antipyretic effectiveness of aspirin, acetaminophen, choline salicylate and placebo in febrile children. Jun 1991.A phase IV double-blind multicenter study comparing the antipyretic effectiveness of aspirin, acetaminophen, choline salicylate and placebo in febrile children. Jun 1991.
    Active substance: DIRITHROMYCIN
    Study summary document link (including results):
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    Document reference: 26233
    Study title: Intrahepatic Arterial Injections of Cisplatin-Phosphatidylcholine-Lipiodol Suspension in Two Unresectable Hepatoblastoma Cases
    Active substance: Ethyl esters of iodized fatty acids of poppy seed oil
    Study summary document link (including results):
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    Document reference: 39952
    Study title: Combined effect of nifedipine and diltiazem on methacholine−induced bronchoconstriction in asthmatic patients. Kivity S, Brayer M, TopilskyM. Annals of allergy, Feb 1992, vol. 68, no. 2, p. 175−9Combined effect of nifedipine and diltiazem on methacholine−induced bronchoconstriction in asthmatic patients. Kivity S, Brayer M, TopilskyM. Annals of allergy, Feb 1992, vol. 68, no. 2, p. 175−9
    Active substance: DILTIAZEM
    Study summary document link (including results):
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    Document reference: 26143
    Study title: Effect of diltiazem on methacholine−induced bronchoconstriction in extrinsic asthmatics.Lichey J, Friedrich T, Münski T, Macha N, Huckauf H. Respiration; international review of thoracic diseases, 1986, vol. 50, no. 1, p. 44−8Effect of diltiazem on methacholine−induced bronchoconstriction in extrinsic asthmatics.Lichey J, Friedrich T, Münski T, Macha N, Huckauf H. Respiration; international review of thoracic diseases, 1986, vol. 50, no. 1, p. 44−8
    Active substance: DILTIAZEM
    Study summary document link (including results):
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    Document reference: 26152
    Study title: CIOMS Line ListingDoyle J. - Clinical Trials Journal London (1969) 83-86
    Active substance: CETALKONIUM AND CHOLINE SALICYLATE
    Study summary document link (including results):
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    Document reference: 23652
    Study title: Doyle J. - Clinical Trials Journal London (1969) 83-86Doyle J. - Clinical Trials Journal London (1969) 83-86
    Active substance: CETALKONIUM AND CHOLINE SALICYLATE
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    Document reference: 23641
    Study title: Firu, P. - Schweiz. Rundschau Med. (Praxis) 65 (1976) 111-116Firu, P. - Schweiz. Rundschau Med. (Praxis) 65 (1976) 111-116
    Active substance: CETALKONIUM AND CHOLINE SALICYLATE
    Study summary document link (including results):
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    Document reference: 23638
    Study title: Firu, P. - Schweiz. Rundschau Med. (Praxis) 65 (1976) 111-116
    Active substance: CETALKONIUM AND CHOLINE SALICYLATE
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    Document reference: 23649
    Study title: Greenwood, A.H. - J. Dental. Med. 20 (1965) 99-103Greenwood, A.H. - J. Dental. Med. 20 (1965) 99-103
    Active substance: CETALKONIUM AND CHOLINE SALICYLATE
    Study summary document link (including results):
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    Document reference: 23633
    Study title: Greenwood, A.H. - J. Dental. Med. 20 (1965) 99-103
    Active substance: CETALKONIUM AND CHOLINE SALICYLATE
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    Document reference: 23644
    Study title: Guggenheim, B. - Schweiz. med. Wschr. 111 (1982) 232-234
    Active substance: CETALKONIUM AND CHOLINE SALICYLATE
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    Document reference: 23651
    Study title: Guggenheim, B. - Schweiz. med. Wschr. 111 (1982) 232-234CIOMS Line ListingGuggenheim, B. - Schweiz. med. Wschr. 111 (1982) 232-234CIOMS Line Listing
    Active substance: CETALKONIUM AND CHOLINE SALICYLATE
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    Document reference: 23640
    Study title: Joliey, H.M. - J. Canad. Dent. Assn. 38 (1972) 72-74Joliey, H.M. - J. Canad. Dent. Assn. 38 (1972) 72-74
    Active substance: CETALKONIUM AND CHOLINE SALICYLATE
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    Document reference: 23637
    Study title: Joliey, H.M. - J. Canad. Dent. Assn. 38 (1972) 72-74
    Active substance: CETALKONIUM AND CHOLINE SALICYLATE
    Study summary document link (including results):
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    Document reference: 23648
    Study title: Lum-Kam, G. - J. Canad. Dent. Assn. 35 (1969) 216-219Lum-Kam, G. - J. Canad. Dent. Assn. 35 (1969) 216-219
    Active substance: CETALKONIUM AND CHOLINE SALICYLATE
    Study summary document link (including results):
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    Document reference: 23634
    Study title: Lum-Kam, G. - J. Canad. Dent. Assn. 35 (1969) 216-219
    Active substance: CETALKONIUM AND CHOLINE SALICYLATE
    Study summary document link (including results):
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    Document reference: 23645
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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