- Trials with a EudraCT protocol (587)
- Paediatric studies in scope of Art45 of the Paediatric Regulation (50)

These are paediatric studies completed by 26 January 2007, in respect of products authorised in the Community (Article 45 of the Paediatric Regulation (EC) No 1901/2006). | |
Note: Advanced search filters for country, trial phase, gender, rare disease, IMP with orphan designation in the indication and age ranges of in-utero, adult or elderly do not apply to these records. |
Study title: LSA5 protocl for the treatment of advanced pediatric and adolescent non-hodgkin's lymphoma (NHL) |
Active substance: ASPARAGINASE |
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Document reference: 21933 |
Study title: Forns M et al, Results of the SHOP LNHB98 (LMB89) trial in pediatric patients with B-cell non-Hodgkin's lymphoma, Med Clin (Barc). 2007 May 5;128(17):641-6. Spanish |
Active substance: ETOPOSIDE |
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Document reference: 26918 |
Study title: Atra A et al, Improved cure rate in children with B-cell acute lymphoblastic leukaemia (B-ALL) and stage IV B-cell non-Hodgkin's lymphoma (B-NHL)--results of the UKCCSG 9003 protocol, Br J Cancer. 1998 Jun;77(12):2281-5 |
Active substance: ETOPOSIDE |
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Document reference: 26871 |
Study title: Cairo MS et al, Long-term follow-up of short intensive multiagent chemotherapy without high-dose methotrexate ('Orange') in children with advanced non-lymphoblastic non-Hodgkin's lymphoma: a children's cancer group report, Leukemia. 2002 Apr;16(4):594-600 |
Active substance: ETOPOSIDE |
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Document reference: 26920 |
Study title: Patte, C., Laplanche, A., Bertozzi, A. I., et al. Granulocyte colony-stimulating factor in induction treatment of children with non-Hodgkin's lymphoma: A randomized study of the French Society of Pediatric Oncology Journal of Clinical Oncology 20(2): 441-448.Patte, C., Laplanche, A., Bertozzi, A. I., et al. Granulocyte colony-stimulating factor in induction treatment of children with non-Hodgkin's lymphoma: A randomized study of the French Society of Pediatric Oncology Journal of Clinical Oncology 20(2): 441-448. |
Active substance: FILGASTRIM |
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Document reference: 27274 |
Study title: Gerhartz HH et al. Randomized, double-blind, placebo-controlled, phase III study of recombinant human granulocyte-macrophage colony-stimulating factor as adjunct to induction treatment of high-grade malignant non-Hodgkin's lymphomas. Blood. 1993 Oct 15;82(8):2329-39.Gerhartz HH et al. Randomized, double-blind, placebo-controlled, phase III study of recombinant human granulocyte-macrophage colony-stimulating factor as adjunct to induction treatment of high-grade malignant non-Hodgkin's lymphomas. Blood. 1993 Oct 15;82(8):2329-39. |
Active substance: CYCLOPHOSPHAMIDE |
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Document reference: 24893 |
Study title: Gerhartz HH et al. Randomized, double-blind, placebo-controlled, phase III study of recombinant human granulocyte-macrophage colony-stimulating factor as adjunct to induction treatment of high-grade malignant non-Hodgkin's lymphomas. Blood. 1993 Oct 15;82(8):2329-39.Gerhartz HH et al. Randomized, double-blind, placebo-controlled, phase III study of recombinant human granulocyte-macrophage colony-stimulating factor as adjunct to induction treatment of high-grade malignant non-Hodgkin's lymphomas. Blood. 1993 Oct 15;82(8):2329-39. |
Active substance: CYCLOPHOSPHAMIDE |
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Document reference: 24894 |
Study title: Gerhartz HH et al. Randomized, double-blind, placebo-controlled, phase III study of recombinant human granulocyte-macrophage colony-stimulating factor as adjunct to induction treatment of high-grade malignant non-Hodgkin's lymphomas. Blood. 1993 Oct 15;82(8):2329-39.Gerhartz HH et al. Randomized, double-blind, placebo-controlled, phase III study of recombinant human granulocyte-macrophage colony-stimulating factor as adjunct to induction treatment of high-grade malignant non-Hodgkin's lymphomas. Blood. 1993 Oct 15;82(8):2329-39. |
Active substance: CYCLOPHOSPHAMIDE |
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Document reference: 24895 |
Study title: Gerhartz HH et al. Randomized, double-blind, placebo-controlled, phase III study of recombinant human granulocyte-macrophage colony-stimulating factor as adjunct to induction treatment of high-grade malignant non-Hodgkin's lymphomas. Blood. 1993 Oct 15;82(8):2329-39.Gerhartz HH et al. Randomized, double-blind, placebo-controlled, phase III study of recombinant human granulocyte-macrophage colony-stimulating factor as adjunct to induction treatment of high-grade malignant non-Hodgkin's lymphomas. Blood. 1993 Oct 15;82(8):2329-39. |
Active substance: CYCLOPHOSPHAMIDE |
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Document reference: 24896 |
Study title: Olivieri A et al. Upfront high-dose sequential therapy (HDS) versus VACOP-B with or without HDS in aggressive non-Hodgkin's lymphoma: long-term results by the NHLCSG. Ann Oncol. 2005 Dec;16(12):1941-8. Epub 2005 Sep 12Olivieri A et al. Upfront high-dose sequential therapy (HDS) versus VACOP-B with or without HDS in aggressive non-Hodgkin's lymphoma: long-term results by the NHLCSG. Ann Oncol. 2005 Dec;16(12):1941-8. Epub 2005 Sep 12 |
Active substance: CYCLOPHOSPHAMIDE |
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Document reference: 25048 |
Study title: Economopoulos T et al. Treatment of intermediate- and high-grade non-Hodgkin's lymphoma using CEOP versus CNOP. Eur J Haematol. 2002 Mar;68(3):135-43.Economopoulos T et al. Treatment of intermediate- and high-grade non-Hodgkin's lymphoma using CEOP versus CNOP. Eur J Haematol. 2002 Mar;68(3):135-43. |
Active substance: CYCLOPHOSPHAMIDE |
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Document reference: 24857 |
Study title: Cairo MS et al Long-term follow-up of short intensive multiagent chemotherapy without high-dose methotrexate ('Orange') in children with advanced non-lymphoblastic non-Hodgkin's lymphoma: a children's cancer group report Leukemia. 2002 Apr;16(4):594-600Cairo MS et al Long-term follow-up of short intensive multiagent chemotherapy without high-dose methotrexate ('Orange') in children with advanced non-lymphoblastic non-Hodgkin's lymphoma: a children's cancer group report Leukemia. 2002 Apr;16(4):594-600 |
Active substance: CYCLOPHOSPHAMIDE |
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Document reference: 24805 |
Study title: Intragumtornchai T et al. CHOP versus CHOP plus ESHAP and high-dose therapy with autologous peripheral blood progenitor cell transplantation for high-intermediate-risk and high-risk aggressive non-Hodgkin's lymphoma. Clin Lymphoma. 2000 Dec;1(3):219-25Intragumtornchai T et al. CHOP versus CHOP plus ESHAP and high-dose therapy with autologous peripheral blood progenitor cell transplantation for high-intermediate-risk and high-risk aggressive non-Hodgkin's lymphoma. Clin Lymphoma. 2000 Dec;1(3):219-25 |
Active substance: CYCLOPHOSPHAMIDE |
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Document reference: 24936 |
Study title: Intragumtornchai T et al. CHOP versus CHOP plus ESHAP and high-dose therapy with autologous peripheral blood progenitor cell transplantation for high-intermediate-risk and high-risk aggressive non-Hodgkin's lymphoma. Clin Lymphoma. 2000 Dec;1(3):219-25 Intragumtornchai T et al. CHOP versus CHOP plus ESHAP and high-dose therapy with autologous peripheral blood progenitor cell transplantation for high-intermediate-risk and high-risk aggressive non-Hodgkin's lymphoma. Clin Lymphoma. 2000 Dec;1(3):219-25 |
Active substance: CYCLOPHOSPHAMIDE |
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Document reference: 24937 |
Study title: Advani S et al Preliminary report of an intensified, short duration chemotherapy protocol for the treatment of pediatric non-Hodgkin's lymphoma in India Ann Oncol. 1997 Sep;8(9):893-7Advani S et al Preliminary report of an intensified, short duration chemotherapy protocol for the treatment of pediatric non-Hodgkin's lymphoma in India Ann Oncol. 1997 Sep;8(9):893-7 |
Active substance: CYCLOPHOSPHAMIDE |
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Document reference: 24716 |
Study title: Anderson JR et al. Long-term follow-up of patients treated with COMP or LSA2L2 therapy for childhood non-Hodgkin's lymphoma: a report of CCG-551 from the Childrens Cancer Group. J Clin Oncol. 1993 Jun;11(6):1024-32Anderson JR et al. Long-term follow-up of patients treated with COMP or LSA2L2 therapy for childhood non-Hodgkin's lymphoma: a report of CCG-551 from the Childrens Cancer Group. J Clin Oncol. 1993 Jun;11(6):1024-32 |
Active substance: CYCLOPHOSPHAMIDE |
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Document reference: 24722 |
Study title: Kluin-Nelemans HC et al. Standard chemotherapy with or without high-dose chemotherapy for aggressive non-Hodgkin's lymphoma: randomized phase III EORTC study. J Natl Cancer Inst. 2001 Jan 3;93(1):22-30.Kluin-Nelemans HC et al. Standard chemotherapy with or without high-dose chemotherapy for aggressive non-Hodgkin's lymphoma: randomized phase III EORTC study. J Natl Cancer Inst. 2001 Jan 3;93(1):22-30. |
Active substance: CYCLOPHOSPHAMIDE |
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Document reference: 24962 |
Study title: Gad-el-Mawla N et al Prolonged disease-free survival in pediatric non-Hodgkin's lymphoma using ifosfamide-containing combination chemotherapy Hematol Oncol. 1991 Jul-Oct;9(4-5):281-6Gad-el-Mawla N et al Prolonged disease-free survival in pediatric non-Hodgkin's lymphoma using ifosfamide-containing combination chemotherapy Hematol Oncol. 1991 Jul-Oct;9(4-5):281-6 |
Active substance: CYCLOPHOSPHAMIDE |
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Document reference: 24887 |
Study title: Tubergen DG et al. Comparison of treatment regimens for pediatric lymphoblastic non-Hodgkin's lymphoma: a Childrens Cancer Group study. J Clin Oncol. 1995 Jun;13(6):1368-76Tubergen DG et al. Comparison of treatment regimens for pediatric lymphoblastic non-Hodgkin's lymphoma: a Childrens Cancer Group study. J Clin Oncol. 1995 Jun;13(6):1368-76 |
Active substance: CYCLOPHOSPHAMIDE |
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Document reference: 24760 |
Study title: Tubergen DG et al. Comparison of treatment regimens for pediatric lymphoblastic non-Hodgkin's lymphoma: a Childrens Cancer Group study. J Clin Oncol. 1995 Jun;13(6):1368-76Tubergen DG et al. Comparison of treatment regimens for pediatric lymphoblastic non-Hodgkin's lymphoma: a Childrens Cancer Group study. J Clin Oncol. 1995 Jun;13(6):1368-76 |
Active substance: CYCLOPHOSPHAMIDE |
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Document reference: 25149 |