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Clinical trials for Pathophysiology

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44380   clinical trials with a EudraCT protocol, of which   7392   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
    Advanced Search: Search tools
     
    Query did not match any clinical trials.
    These are paediatric studies completed by 26 January 2007, in respect of products authorised in the Community (Article 45 of the Paediatric Regulation (EC) No 1901/2006).
    Note: Advanced search filters for country, trial phase, gender, rare disease, IMP with orphan designation in the indication and age ranges of in-utero, adult or elderly do not apply to these records.
    Study title: Welte, K. and Dale, D. Pathophysiology and treatment of severe chronic neutropenia Annals of Hematology 72(4): 158-65.Welte, K. and Dale, D. Pathophysiology and treatment of severe chronic neutropenia Annals of Hematology 72(4): 158-65.
    Active substance: FILGASTRIM
    Study summary document link (including results):
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    Document reference: 27284
    Study title: FINESCHI-S, OKOLICSANYI-L. L. OKOLICSANYI, CATTEDRA DI GASTROENTEROLOGIA, ISTITUTO DI SEMEIOTICA MEDIC A, VIA A. GRAMSCI 14, 43100 PARMA, ITALY. PATHOPHYSIOLOGY AND TREATMENT OF IRRITABLE BOWEL SYNDROME. ARGOMENTI DI GASTROENTEROLOGIA CLINICA {ARGOMENTI-GASTROENTEROL- CLIN}, 1999 VOL/ISS/PG. 12/2 (49-59),FINESCHI-S, OKOLICSANYI-L. L. OKOLICSANYI, CATTEDRA DI GASTROENTEROLOGIA, ISTITUTO DI SEMEIOTICA MEDIC A, VIA A. GRAMSCI 14, 43100 PARMA, ITALY. PATHOPHYSIOLOGY AND TREATMENT OF IRRITABLE BOWEL SYNDROME. ARGOMENTI DI GASTROENTEROLOGIA CLINICA {ARGOMENTI-GASTROENTEROL- CLIN}, 1999 VOL/ISS/PG. 12/2 (49-59),
    Active substance: TRIMEBUTINE
    Study summary document link (including results):
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    Document reference: 46753
    Study title: Endocrine disorders in newborn - Bongiovanni AM et al - 1981 - In Avery GB (Ed): Neonatalogy: Pathophysiology and Management of the Newborn, 2nd Ed. JB Lippincott, Philadelphia, 1981; pp 1104-1127) - Publication in the Comprehensive Summary of Hydrocortison in dated 27/06/1995 -
    Active substance: HYDROCORTIZONE
    Study summary document link (including results):
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    Document reference: 29162
    Study title: Neonatology: Pathophysiology and Management of the Newborn - Avery GB - 1981 (2nd ed. JB Lippincott Company, Philadelphia, PA, 1981) - Publication in the Comprehensive Summary of Hydrocortisone dated 27/06/1995 -
    Active substance: HYDROCORTIZONE
    Study summary document link (including results):
    View full study record
    Document reference: 29163
    Study title: Dyslipidemia in pediatric renal disease: epidemiology, pathophysiology and management
    Active substance: PRAVASTATIN
    Study summary document link (including results):
    View full study record
    Document reference: 46093
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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