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Clinical trials for Solid Tumor

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44380   clinical trials with a EudraCT protocol, of which   7392   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    Query did not match any clinical trials.
    These are paediatric studies completed by 26 January 2007, in respect of products authorised in the Community (Article 45 of the Paediatric Regulation (EC) No 1901/2006).
    Note: Advanced search filters for country, trial phase, gender, rare disease, IMP with orphan designation in the indication and age ranges of in-utero, adult or elderly do not apply to these records.
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    Study title: Phase II Study of Arsenic Trioxide in Neuroblastoma and other Pediatric solid tumors.
    Active substance: arsenic trioxide
    Study summary document link (including results): Trisenox CTI 1059.xls
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    Document reference: 39686
    Study title: Mathew P et al Phase I study of oral etoposide in children with refractory solid tumors J Clin Oncol 1994 Jul;12(7):1452-7
    Active substance: ETOPOSIDE
    Study summary document link (including results):
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    Document reference: 26760
    Study title: Mathew P et al, Phase I study of oral etoposide in children with refractory solid tumors, J Clin Oncol 1994 Jul;12(7):1452-7
    Active substance: ETOPOSIDE
    Study summary document link (including results):
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    Document reference: 26814
    Study title: Santana VM et al Escalating sequential high-dose carboplatin and etoposide with autologous marrow support in children with relapsed solid tumors Bone Marrow Transplant 1992 Nov;10(5):457-62
    Active substance: ETOPOSIDE
    Study summary document link (including results):
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    Document reference: 26750
    Study title: Santana VM et al, Escalating sequential high-dose carboplatin and etoposide with autologous marrow support in children with relapsed solid tumors, Bone Marrow Transplant 1992 Nov;10(5):457-62
    Active substance: ETOPOSIDE
    Study summary document link (including results):
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    Document reference: 26804
    Study title: Gadner H et al High-dose melphalan, etoposide, and carboplatin (MEC) +/- fractionated total body irradiation for treatment of advanced solid tumors Pediatr Hematol Oncol 1992 Apr-Jun;9(2):v-viii. No abstract available
    Active substance: ETOPOSIDE
    Study summary document link (including results):
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    Document reference: 26751
    Study title: Gadner H et al, High-dose melphalan, etoposide, and carboplatin (MEC) +/- fractionated total body irradiation for treatment of advanced solid tumors, Pediatr Hematol Oncol 1992 Apr-Jun;9(2):v-viii. No abstract available
    Active substance: ETOPOSIDE
    Study summary document link (including results):
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    Document reference: 26805
    Study title: Kung FH et al Ifosfamide/etoposide combination in the treatment of recurrent malignant solid tumors of childhood. A Pediatric Oncology Group Phase II study Cancer 1993 Mar 1;71(5):1898-903
    Active substance: ETOPOSIDE
    Study summary document link (including results):
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    Document reference: 26762
    Study title: Kung FH et al, Ifosfamide/carboplatin/etoposide (ICE) for recurrent malignant solid tumors of, childhood: a Pediatric Oncology Group Phase I/II study, J Pediatr Hematol Oncol. 1995 Aug;17(3):265-9
    Active substance: ETOPOSIDE
    Study summary document link (including results):
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    Document reference: 26948
    Study title: Kung FH et al, Ifosfamide/etoposide combination in the treatment of recurrent malignant solid tumors of childhood. A Pediatric Oncology Group Phase II study, Cancer 1993 Mar 1;71(5):1898-903
    Active substance: ETOPOSIDE
    Study summary document link (including results):
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    Document reference: 26816
    Study title: Pratt CB et al Response of pediatric malignant solid tumors following ifosfamide or ifosfamide/carboplatin/etoposide: a single hospital experience.Med Pediatr Oncol 1996 Sep;27(3):145-8
    Active substance: ETOPOSIDE
    Study summary document link (including results):
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    Document reference: 26759
    Study title: Pratt CB et al, Response of pediatric malignant solid tumors following ifosfamide or ifosfamide/carboplatin/etoposide: a single hospital experience., Med Pediatr Oncol 1996 Sep;27(3):145-8
    Active substance: ETOPOSIDE
    Study summary document link (including results):
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    Document reference: 26813
    Study title: Loss JF et al Outcome of pediatric recurrent and refractory malignant solid tumors following ifosfamide/carboplatin/etoposide (ICE): A phase II study in a pediatric oncology centre in Brazil Pediatr Blood Cancer 2004 Feb;42(2):139-44
    Active substance: ETOPOSIDE
    Study summary document link (including results):
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    Document reference: 26755
    Study title: Cairo MS et al Prospective randomized trial between two doses of granulocyte colony-stimulating factor after ifosfamide, carboplatin, and etoposide in children with recurrent or refractory solid tumors: a children's cancer group report J Pediatr Hematol Oncol 2001 Jan;23(1):30-8
    Active substance: ETOPOSIDE
    Study summary document link (including results):
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    Document reference: 26757
    Study title: Cairo MS et al, Prospective randomized trial between two doses of granulocyte colony-stimulating factor after ifosfamide, carboplatin, and etoposide in children with recurrent or refractory solid tumors: a children's cancer group report, J Pediatr Hematol Oncol 2001 Jan;23(1):30-8
    Active substance: ETOPOSIDE
    Study summary document link (including results):
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    Document reference: 26811
    Study title: Carpenter PA et al A dose-intensive, cyclophosphamide-based regimen for the treatment of recurrent/progressive or advanced solid tumors of childhood: a report from the Australia and New Zealand Children's Cancer Study Group Cancer 1997 Aug 1;80(3):489-96
    Active substance: ETOPOSIDE
    Study summary document link (including results):
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    Document reference: 26748
    Study title: Loss JF et al, Outcome of pediatric recurrent and refractory malignant solid tumors following ifosfamide/carboplatin/etoposide (ICE): A phase II study in a pediatric oncology centre in Brazil, Pediatr Blood Cancer 2004 Feb;42(2):139-44
    Active substance: ETOPOSIDE
    Study summary document link (including results):
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    Document reference: 26809
    Study title: White L et al Dose-intensive cyclophosphamide with etoposide and vincristine for pediatric solid tumors: a phase I/II pilot study by the Australia and New Zealand Childhood Cancer Study Group J Clin Oncol 1994 Mar;12(3):522-31
    Active substance: ETOPOSIDE
    Study summary document link (including results):
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    Document reference: 26761
    Study title: White L et al, Dose-intensive cyclophosphamide with etoposide and vincristine for pediatric solid tumors: a phase I/II pilot study by the Australia and New Zealand Childhood Cancer Study Group, J Clin Oncol 1994 Mar;12(3):522-31
    Active substance: ETOPOSIDE
    Study summary document link (including results):
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    Document reference: 26815
    Study title: Mantadakis E et al Fractionated cyclophosphamide and etoposide for children with advanced or refractory solid tumors: a phase II window study J Clin Oncol 2000 Jul;18(13):2576-81
    Active substance: ETOPOSIDE
    Study summary document link (including results):
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    Document reference: 26753
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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