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Clinical trials for Toxic

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44339   clinical trials with a EudraCT protocol, of which   7369   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    Query did not match any clinical trials.
    These are paediatric studies completed by 26 January 2007, in respect of products authorised in the Community (Article 45 of the Paediatric Regulation (EC) No 1901/2006).
    Note: Advanced search filters for country, trial phase, gender, rare disease, IMP with orphan designation in the indication and age ranges of in-utero, adult or elderly do not apply to these records.
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    Study title: Tolérance de 5 jours par voie orale chez le raton et le rat adulte suivie d’une période sans traitement de 15 jours (documentation toxicologique du dossier d’AMM du 30/10/87 du spectral enfant solution buvable 40mg/ml) - Briffaux - 02/10/1987
    Active substance: ACEBUTOLOL
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    Document reference: 46194
    Study title: Evaluation of anthroposophic supportive medicine on treatment -related toxicity in children receiving cancer therapy.
    Active substance: acqueous extract(1:20) from fresh herb of white-berry mistletoe (Viscum album L.): HELIXOR® A: produced from mistletoe growing on fir (Viscum album L. abietis), HELIXOR® M: produced from mistletoe growing on apple tree (Viscum album L. mali), HELIXOR® P: produced from mistletoe growing on pine (Viscum album L. pini)
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    Document reference: 39775
    Study title: Aluminium toxicity in childhood - Sedman A. - 1992 (Pediatr Nephrol 1992; 6(4): 383-393) Publication in Clinical Overview - Aluminium hydroxide and combination - Anaemia Microcytic - Caratas M. - 2006Aluminium toxicity in childhood - Sedman A. - 1992 (Pediatr Nephrol 1992; 6(4): 383-393) Publication in Clinical Overview - Aluminium hydroxide and combination - Anaemia Microcytic - Caratas M. - 2006
    Active substance: ALGELDRATE + MAGNESIUM HYDROXIDE + SIMETICONE/ ALDEGRATE+ MAGNESIUM HYDROXIDE
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    Document reference: 46412
    Study title: Aluminium toxicity in childhood. Pediatric nephrology, Jul 1992, vol.6, no. 4, p. 383-93, 68 refs, ISSN:0931-041 X. Sedman-A.Aluminium toxicity in childhood. Pediatric nephrology, Jul 1992, vol.6, no. 4, p. 383-93, 68 refs, ISSN:0931-041 X. Sedman-A.
    Active substance: ALGELDRATE + MAGNESIUM HYDROXIDE + SIMETICONE/ ALDEGRATE+ MAGNESIUM HYDROXIDE
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    Document reference: 46408
    Study title: Intraperitoneal Deferoxamine Therapy for Aluminium Intoxication in a Child Undergoing Continuous Ambulatory Peritoneal Dialysis. Andreoli-S-P, Dunn-D, DeMyer-W, Sherrard-D-J, Bergstein-J-M. J-Pediatr (107,No.5,760-63,1985) Coden:JOPDAB ISSN:0022-3476.Intraperitoneal Deferoxamine Therapy for Aluminium Intoxication in a Child Undergoing Continuous Ambulatory Peritoneal Dialysis. Andreoli-S-P, Dunn-D, DeMyer-W, Sherrard-D-J, Bergstein-J-M. J-Pediatr (107,No.5,760-63,1985) Coden:JOPDAB ISSN:0022-3476.
    Active substance: ALGELDRATE + MAGNESIUM HYDROXIDE + SIMETICONE/ ALDEGRATE+ MAGNESIUM HYDROXIDE
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    Document reference: 46409
    Study title: Intraperitoneal deferoxamine therapy for aluminium intoxication in achild undergoing continuous ambulatory peritoneal dialysis - Andreoli SP - 1985 (J. of Pediatrics; 107 (5): 760-764)Intraperitoneal deferoxamine therapy for aluminium intoxication in achild undergoing continuous ambulatory peritoneal dialysis - Andreoli SP - 1985 (J. of Pediatrics; 107 (5): 760-764)
    Active substance: ALGELDRATE + MAGNESIUM HYDROXIDE + SIMETICONE/ ALDEGRATE+ MAGNESIUM HYDROXIDE
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    Document reference: 46417
    Study title: Oral toxicity study in juvenile rats
    Active substance: ALFUZOCIN (HYDROCHLORIDE)
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    Document reference: 46380
    Study title: Aluminium toxicity in childhood - Sedman A. - 1992 (Pediatr Nephrol 1992; 6(4): 383-393) Publication in Clinical Overview - Aluminium hydroxide and combination - Anaemia Microcytic - Caratas M. - 2006Aluminium toxicity in childhood - Sedman A. - 1992 (Pediatr Nephrol 1992; 6(4): 383-393) Publication in Clinical Overview - Aluminium hydroxide and combination - Anaemia Microcytic - Caratas M. - 2006
    Active substance: ALUMINIUM HYDROXIDE AND MAGNESIUM HYDROXIDE
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    Document reference: 46469
    Study title: Study N° 430 : Analysis of Amikacin Study 430, Pharmacokinetics, Efficacy and Toxicity of Amikacin Sulfate in the NeonateStudy N° 430 : Analysis of Amikacin Study 430, Pharmacokinetics, Efficacy and Toxicity of Amikacin Sulfate in the Neonate
    Active substance: AMICACIN SULPHATE
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    Document reference: 46560
    Study title: The dialysis dementia syndrome and aluminium intoxication - Sideman S - 1982 (Nephron 1982; 31(1): 1-10) - Publication in Clinical Overview - Aluminium Hydroxide and combination - Dementia - Caratas M - 2006 -The dialysis dementia syndrome and aluminium intoxication - Sideman S - 1982 (Nephron 1982; 31(1): 1-10) - Publication in Clinical Overview - Aluminium Hydroxide and combination - Dementia - Caratas M - 2006 -
    Active substance: ALGELDRATE + MAGNESIUM HYDROXIDE + SIMETICONE/ ALDEGRATE+ MAGNESIUM HYDROXIDE
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    Document reference: 46420
    Study title: Intraperitoneal deferoxamine therapy for aluminium intoxication in achild undergoing continuous ambulatory peritoneal dialysis - Andreoli SP - 1985 (J. of Pediatrics; 107 (5): 760-764)Intraperitoneal deferoxamine therapy for aluminium intoxication in achild undergoing continuous ambulatory peritoneal dialysis - Andreoli SP - 1985 (J. of Pediatrics; 107 (5): 760-764)
    Active substance: ALUMINIUM HYDROXIDE AND MAGNESIUM HYDROXIDE
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    Document reference: 46474
    Study title: The dialysis dementia syndrome and aluminium intoxication - Sideman S - 1982 (Nephron 1982; 31(1): 1-10) - Publication in Clinical Overview - Aluminium Hydroxide and combination - Dementia - Caratas M - 2006 -The dialysis dementia syndrome and aluminium intoxication - Sideman S - 1982 (Nephron 1982; 31(1): 1-10) - Publication in Clinical Overview - Aluminium Hydroxide and combination - Dementia - Caratas M - 2006 -
    Active substance: ALUMINIUM HYDROXIDE AND MAGNESIUM HYDROXIDE
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    Document reference: 46478
    Study title: Amantadine neurotoxicity in a pediatric patient with renal insufficiency.Amantadine neurotoxicity in a pediatric patient with renal insufficiency.
    Active substance: AMANTADINE
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    Document reference: 46499
    Study title: "Acute pulmonary toxicity in an infant from intravenous amiodarone. - Daniels CJ et al. - 1997 (Am. Cardiol., 80 (8): 1113-1116) ; - Publication in CES EXPCRC-CES0172-EN01, CES EXPCRC-CES0173-EN01, CES EXPCRC-CES0206-EN01 -" "Acute pulmonary toxicity in an infant from intravenous amiodarone. - Daniels CJ et al. - 1997 (Am. Cardiol., 80 (8): 1113-1116) ; - Publication in CES EXPCRC-CES0172-EN01, CES EXPCRC-CES0173-EN01, CES EXPCRC-CES0206-EN01 -"
    Active substance: AMIODARONE
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    Document reference: 45209
    Study title: "Optimizing oral dosing and monitoring of noncardiac toxicities with chronic amiodarone therapy. - Tsikouris JP et al. - 2000 (Connecticut Medecine, 64: 35-38) ; - Publication in CES EXPCRC-CES0172-EN01, CES EXPCRC-CES0173-EN01, CES EXPCRC-CES0206-EN01 -" "Optimizing oral dosing and monitoring of noncardiac toxicities with chronic amiodarone therapy. - Tsikouris JP et al. - 2000 (Connecticut Medecine, 64: 35-38) ; - Publication in CES EXPCRC-CES0172-EN01, CES EXPCRC-CES0173-EN01, CES EXPCRC-CES0206-EN01 -"
    Active substance: AMIODARONE
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    Document reference: 45185
    Study title: Acute toxicity of KWD2183 in young rats after single oral administration
    Active substance: BAMBUTEROL HYDROCHLORIDE
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    Document reference: 22123
    Study title: General toxicity of KWD2183 given orally to young rats for three months
    Active substance: BAMBUTEROL HYDROCHLORIDE
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    Document reference: 22124
    Study title: General toxicity of bambuterol (KWD2183) given orally to young rats for three months. Plasma concentration study. (Appendix 4:2 to report T2030)
    Active substance: BAMBUTEROL HYDROCHLORIDE
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    Document reference: 22125
    Study title: Reversal of antiparkinsonian drug toxicity by physostigmine: a controlled study.
    Active substance: BENZATROPINE
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    Document reference: 22253
    Study title: Reversal of antiparkinsonian drug toxicity by physostigmine: a controlled study.
    Active substance: BENZATROPINE
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    Document reference: 41957
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    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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