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Clinical trials for Trophoblast

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44381   clinical trials with a EudraCT protocol, of which   7393   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
    Advanced Search: Search tools
     
    Query did not match any clinical trials.
    These are paediatric studies completed by 26 January 2007, in respect of products authorised in the Community (Article 45 of the Paediatric Regulation (EC) No 1901/2006).
    Note: Advanced search filters for country, trial phase, gender, rare disease, IMP with orphan designation in the indication and age ranges of in-utero, adult or elderly do not apply to these records.
    Study title: Single-dose methotrexate regimen in the treatment of low-risk gestational trophoblastic neoplasia
    Active substance: DACTINOMYCIN
    Study summary document link (including results):
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    Document reference: 25461
    Study title: Primary treatment of metastatic high-risk gestational trophoblastic neoplasia with EMA-CO chemotherapy.
    Active substance: DACTINOMYCIN
    Study summary document link (including results):
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    Document reference: 25428
    Study title: Relapse rate of patients with low-risk gestational trophoblastic tumor initially treated with single-agent chemotherapy
    Active substance: DACTINOMYCIN
    Study summary document link (including results):
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    Document reference: 25442
    Study title: Actinomycin D--the drug of choice for initial therapy of gestational trophoblastic disease.
    Active substance: DACTINOMYCIN
    Study summary document link (including results):
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    Document reference: 25285
    Study title: Treatment of high-risk gestational trophoblastic neoplasia with etoposide, methotrexate, actinomycin D, cyclophosphamide, and vincristine chemotherapy.
    Active substance: DACTINOMYCIN
    Study summary document link (including results):
    View full study record
    Document reference: 25490
    Study title: Weekly intramuscular methotrexate for nonmetastatic gestational trophoblastic disease.
    Active substance: DACTINOMYCIN
    Study summary document link (including results):
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    Document reference: 25512
    Study title: Comparison of pulse methotrexate and pulse dactinomycin in the treatment of low-risk gestational trophoblastic neoplasia.
    Active substance: DACTINOMYCIN
    Study summary document link (including results):
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    Document reference: 25321
    Study title: Doppler study of myometrium in invasive gestational trophoblastic disease.
    Active substance: DACTINOMYCIN
    Study summary document link (including results):
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    Document reference: 25333
    Study title: Early detection of persistent trophoblastic tumour by serum human chorionic gonadotrophin monitoring after molar pregnancy.
    Active substance: DACTINOMYCIN
    Study summary document link (including results):
    View full study record
    Document reference: 25336
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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