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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44352   clinical trials with a EudraCT protocol, of which   7379   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    10,988 result(s) found. Displaying page 144 of 550.
    «« First « Previous 140  141  142  143  144  145  146  147  148  Next» Last»»
    EudraCT Number: 2010-021515-17 Sponsor Protocol Number: N/A Start Date*: 2010-09-30
    Sponsor Name:Imperial College London
    Full Title: RiFL: Rifaxamin in Fatty Liver Disease. Does Modulation of Gut Microbiota Reduce Hepatic Inflammation in Non-Alcoholic Steatohepatitis (NASH)?
    Medical condition: Non-alcoholic steatohepatitis (NASH)
    Disease: Version SOC Term Classification Code Term Level
    12.1 10053219 non-alcoholic steatohepatitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-022817-24 Sponsor Protocol Number: OVG 2010/03 Start Date*: 2010-10-18
    Sponsor Name:University of Oxford
    Full Title: A multi-centre, open-label, clinical, phase 4 trial, following on from a head-to-head comparison study of two H1N1 influenza vaccines in children, to compare firstly, the persistence of antibody ag...
    Medical condition: Prevention of Influenza infections
    Disease: Version SOC Term Classification Code Term Level
    12.0 10059429 Influenza immunisation LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-005717-38 Sponsor Protocol Number: D8480C00046 Start Date*: 2006-08-15
    Sponsor Name:AstraZeneca AB
    Full Title: An Open-Label, Phase II Study to Evaluate the Biological Activity of AZD2171, as Measured by FDG-PET Response, in Patients with Metastatic Gastro-Intestinal Stromal Tumours (GIST) Resistant or Into...
    Medical condition: Metastatic Gastro-Intestinal Stromal Tumours
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-007322-19 Sponsor Protocol Number: RPC190 Start Date*: 2009-07-07
    Sponsor Name:Queen Victoria Hospital NHS Foundation Trust
    Full Title: A Comparison of Remifentanil Patient-Controlled Analgesia vs. Oral Morphine Analgesia for Dressing Changes in Burns Patients.
    Medical condition: Pain experienced by patients with pre-existing burns presenting to the burns outpatients unit requiring two or more dressing changes
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-003727-23 Sponsor Protocol Number: RRK3563 Start Date*: 2008-12-16
    Sponsor Name:University Hospital Birmingham NHS Foundation Trust
    Full Title: Does phosphate binding with sevelamer carbonate improve cardiovascular structure and function in patients with early chronic kidney disease?
    Medical condition: Chronic kidney disease stage 3 (eGFR 30-59 ml/min/1.73m2)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10064848 Chronic kidney disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-021813-22 Sponsor Protocol Number: 781875 Start Date*: 2010-12-23
    Sponsor Name:Central Manchester University Hospitals NHS Foundation Trust
    Full Title: The Anticoagulation of Calf Thrombosis (ACT) Study: A randomised controlled trial comparing standardised anticoagulation versus conservative therapy in the treatment of below knee deep vein thrombo...
    Medical condition: DVT of the calf / below knee region.
    Disease: Version SOC Term Classification Code Term Level
    12 10013878 DVT of calf LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-012928-89 Sponsor Protocol Number: 1.1042009 Start Date*: 2009-10-21
    Sponsor Name:South Tees NHS Trust
    Full Title: Intrathecal injection of a single dose of Ziconotide (Prialt®) to evaluate the option of continuous administration via implanted pump. A Pilot Study
    Medical condition: Severe, Chronic pain in patients who require intrathecal analgesia
    Disease: Version SOC Term Classification Code Term Level
    101 10049475 Chronic pain LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-019647-19 Sponsor Protocol Number: MAC_001 Start Date*: 2011-02-04
    Sponsor Name:University of Oxford
    Full Title: A double blind randomised placebo controlled trial of montelukast in the treatment of acute persistent cough in young people and adults (aged 16-49) in primary care
    Medical condition: Acute persistent cough with no established diagnosis
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-008441-38 Sponsor Protocol Number: ISRCTN76912190 Start Date*: 2011-02-17
    Sponsor Name:London School Of Hygiene and Tropical Medicine
    Full Title: Tranexamic acid for the treatment of postpartum haemorrhage: An international randomised, double blind, placebo controlled trial
    Medical condition: Postpartum haemorrhage
    Disease: Version SOC Term Classification Code Term Level
    13.1 10036417 Post-partum haemorrhage LLT
    Population Age: Adolescents, Under 18, Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-007984-17 Sponsor Protocol Number: PETC1002 Start Date*: 2009-03-02
    Sponsor Name:Moorfields Eye Hospital NHS Foundation Trust
    Full Title: Pilot randomised placebo-controlled double-masked clinical trial of subconjunctival Bevacizumab on eyes with recent onset of corneal neovascularisation
    Medical condition: Corneal neovascularisation
    Disease: Version SOC Term Classification Code Term Level
    9.1 10055665 Corneal neovascularisation LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-007319-33 Sponsor Protocol Number: OP08/8679 Start Date*: 2009-02-19
    Sponsor Name:Leeds Teaching Hospitals NHS Trust
    Full Title: Do genes predict response to treatment in age-related macular degeneration?
    Medical condition: Choroidal neovascularisation secondary to age-related macular degeneration (ARMD)
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-021630-63 Sponsor Protocol Number: GA1001 Start Date*: 2011-03-28
    Sponsor Name:Reckitt Benckiser
    Full Title: A randomised, double blind placebo controlled study in patients with reflux symptoms to assess suppression of gastro-oesophageal reflux by ‘Gaviscon Double Action Peppermint liquid’ using the BRAVO...
    Medical condition: Gastro-oesophageal reflux disease (GORD)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2005-004833-17 Sponsor Protocol Number: CBD VP 128/05 Start Date*: 2009-05-01
    Sponsor Name:Dstl
    Full Title: Assessment of the effect of prior anthrax vaccine precipitated (AVP) vaccination on the immune response to booster AVP vaccination.
    Medical condition: Vaccination against potential exposure to anthrax (Bacillus anthracis).
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-016223-56 Sponsor Protocol Number: 2478-INT-001 Start Date*: 2010-09-02
    Sponsor Name:Kyowa Hakko Kirin Pharma, Inc.
    Full Title: An Open-Label, Dose Escalation, Multicenter Phase 1/2 Study of KW-2478 in Combination with Bortezomib in Subjects with Relapsed and/or Refractory Multiple Myeloma
    Medical condition: Multiple Myeloma
    Disease: Version SOC Term Classification Code Term Level
    13.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10028228 Multiple myeloma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-000087-83 Sponsor Protocol Number: 2929 Start Date*: 2008-12-19
    Sponsor Name:University of Liverpool [...]
    1. University of Liverpool
    2. The Royal Liverpool and Broadgreen University Hospitals NHS Trust
    Full Title: EUROPAC2 trial to investigate the efficacy of ANTOX(vers) 1.2 and MGCT (magnesiocard) for the treatment of hereditary pancreatitis and idiopathic chronic pancreatitis.
    Medical condition: Hereditary Pancreatitis and Idiopathic Chronic Pancreatitis
    Disease: Version SOC Term Classification Code Term Level
    13.1 10017947 - Gastrointestinal disorders 10033646 Acute and chronic pancreatitis HLT
    13.1 10010331 - Congenital, familial and genetic disorders 10056976 Hereditary pancreatitis PT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2007-000493-23 Sponsor Protocol Number: A2260335 Start Date*: 2007-04-05
    Sponsor Name:GlaxoSmithKline Consumer Healthcare
    Full Title: A Comparison of Two Analgesic Products for the Treatment of Headache
    Medical condition: Treatment of tension headache
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-023910-30 Sponsor Protocol Number: RR10/9592 Start Date*: 2011-03-23
    Sponsor Name:University of Leeds
    Full Title: A Prospective, Single-centre, Randomised Study Evaluating the Clinical, Imaging and Immunological Depth of Remission Achieved by Very Early versus Delayed Etanercept in patients with Rheumatoid Art...
    Medical condition: Rheumatoid Arthritis
    Disease: Version SOC Term Classification Code Term Level
    13.1 10028395 - Musculoskeletal and connective tissue disorders 10039073 Rheumatoid arthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-012043-42 Sponsor Protocol Number: RSCH 01/10 Start Date*: 2011-07-11
    Sponsor Name:Royal Surrey County Hospital NHS Trust
    Full Title: The Effect of a Human Surgical Sealant on Range of Motion in Total Knee Replacement
    Medical condition: Use of human surgical sealant during total knee replacement and if this affects knee movement for the 1st year after surgery.
    Disease: Version SOC Term Classification Code Term Level
    13.1 10042613 - Surgical and medical procedures 10057129 Revision of total knee arthroplasty LLT
    13.1 10042613 - Surgical and medical procedures 10044094 Total knee replacement LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-002405-47 Sponsor Protocol Number: The CogNaive Study Start Date*: 2007-07-31
    Sponsor Name:Imperial College
    Full Title: A randomised prospective study assessing changes in neuro-cognitive function, using a computerised test battery, in treatment naïve HIV-1 positive subjects commencing two different antiretroviral r...
    Medical condition: HIV
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-021886-63 Sponsor Protocol Number: RD2010-48 Start Date*: 2011-07-14
    Sponsor Name:East and North Hertfordshire NHS Trust [...]
    1. East and North Hertfordshire NHS Trust
    2.
    Full Title: A trial of Prostate Radiotherapy in Conjunction with Carbogen and Nicotinamide (PROCON)
    Medical condition: Prostate Cancer
    Disease: Version SOC Term Classification Code Term Level
    14.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10060862 Prostate cancer PT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: GB (Completed)
    Trial results: (No results available)
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    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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