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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44352   clinical trials with a EudraCT protocol, of which   7380   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    10,988 result(s) found. Displaying page 9 of 550.
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    EudraCT Number: 2004-004761-15 Sponsor Protocol Number: 1 Start Date*: 2005-10-12
    Sponsor Name:City University
    Full Title: Rapid Ejaculation: An exploration of the pharmacological and behavioural therapies in men living in East London and a preliminary trial of these treatment modalities
    Medical condition: Premature ejaculation
    Disease:
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-001214-40 Sponsor Protocol Number: cro085 Start Date*: 2007-08-17
    Sponsor Name:Imperial College London
    Full Title: A trial to compare the effects of nebivolol versus atenolol on various cardiovascular measurements including insulin sensitivity
    Medical condition: Hypertension
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-001222-83 Sponsor Protocol Number: HHSC/001 Start Date*: 2005-12-09
    Sponsor Name:Imperial College London
    Full Title: A phase I/II safety and tolerability dose escalation study following the autologous infusion of expanded adult haemopoietic stem cells to patients with liver insufficiency
    Medical condition: Chronic liver insufficiency
    Disease: Version SOC Term Classification Code Term Level
    9.1 10024667 Liver cirrhosis LLT
    9.1 10024670 Liver disorder LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-000101-54 Sponsor Protocol Number: 8162 Start Date*: 2006-02-10
    Sponsor Name:University Hospitals Leicester, Leicester General Hospital
    Full Title: A randomized, observer-blind, dose-ranging, single-centre, study to evaluate the safety, tolerability and immunogenicity of adjuvanted and non-adjuvanted influenza A/Hong Kong/1073/99 (H9N2) vaccin...
    Medical condition: Vaccine study to assess the safety and immunogenicity of whole virus, alum-adjuvanted whole virus and virosomal A/HongKong/1073/99 (H9N2) vaccine in healthy adult volunteers
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-000115-10 Sponsor Protocol Number: SPON CU 086 Start Date*: 2005-10-14
    Sponsor Name:Cardiff University
    Full Title: A randomised, double blind, placebo-controlled, cross-over study of the effects of dehydroepiandrosterone replacement on vascular function in patients with primary and secondary adrenal insufficiency.
    Medical condition: Primary and secondary adrenal failure
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-000120-17 Sponsor Protocol Number: APL-510-009 Start Date*: 2005-03-24
    Sponsor Name:Alliance Pharmaceuticals Ltd
    Full Title: A double-blind placebo-controlled cross-over study to determine if melatonin can improve the length of day time sleep in subjects with transient misalignment of the sleep-wake cycle as a result of ...
    Medical condition: Transient misalignment of the sleep-wake cycle as a result of working night shifts (insomnia in night shift workers)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-002272-41 Sponsor Protocol Number: S194-INT-04 Start Date*: 2004-12-07
    Sponsor Name:Stiefel Laboratories International Division
    Full Title: A Multi-Centre, Single-Blind, Parallel Group, Clinical Evaluation of the Efficacy and Safety of Duac Gel (A Gel containing Clindamycin Phosphate [Equivalent to 1% Clindamycin] and 5% Benzoyl Peroxi...
    Medical condition: Acne Vulgaris
    Disease: Version SOC Term Classification Code Term Level
    10000519
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-004962-33 Sponsor Protocol Number: M14P5 Start Date*: 2005-03-09
    Sponsor Name:Chiron S.r.l.
    Full Title: A Phase IV, Single Centre, Open-label Study to Investigate the Kinetics of the B Cell Response to the First and the Third Immunization with Chiron Meningococcal C Conjugate Vaccine Menjugate® Admin...
    Medical condition: Healthy subjects without known medicial conditions will be vaccinated against Neisseria meningitidis serogroup C. Active prevention of meningococcal C disease caused by Neisseria meningitidis serog...
    Disease:
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-000047-26 Sponsor Protocol Number: AN05-7301 Start Date*: 2006-03-10
    Sponsor Name:Leeds Teaching Hospitals NHS Trust
    Full Title: A randomized controlled trial of caudal epidural or intravenous fentanyl on the post-operative analgesia requirements after transurethral endoscopic resection of prostate, bladder neck or bladder t...
    Medical condition: Bladder spasm following endoscopic resection for: Bladder tumour Prostate hypertrophy Prostate cancer
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2004-002538-20 Sponsor Protocol Number: EORTC 62027 Start Date*: 2006-02-24
    Sponsor Name:European Organisation for Research and Treatment of Cancer
    Full Title: Phase 2 study of Glivec (Imatinib) in locally advanced and/or metastatic soft tissue sarcomas expressing the t(17;22)(q22;q13) translocation resulting in a COL1A1/PDGF rearrangement i.e. DermatoFib...
    Medical condition: Soft tissue sarcomas are a family of malignant diseases originating from mesenchymal cells. Two types of theses sarcomas, dermatofibrosarcoma protuberans (DFSP) and giant cell fibriblastoma(GCF), a...
    Disease: Version SOC Term Classification Code Term Level
    7.0 10057070 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-002997-31 Sponsor Protocol Number: SCH/05/015 Start Date*: 2006-08-10
    Sponsor Name:Sheffield Children's NHS Trust
    Full Title: A multi-centre randomised trial of insulin detemir in pre-diabetes associated with cystic fibrosis.
    Medical condition: Individuals with cystic fibrosis develop diabetes. They exhibit abnormal glucose handling (impaired glucose tolerance), poor growth and a decline in lung function before overt diabetes develops. E...
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-002612-28 Sponsor Protocol Number: CHTF919D2301E1 Start Date*: 2004-11-17
    Sponsor Name:Novartis Pharmaceuticals UK Ltd
    Full Title: A one year, open label, multi-center, extension study to CHTF919D2301 to assess the long term safety of tegaserod 6 mg bid given orally in female patients with symptoms of dyspepsia
    Medical condition: dyspepsia
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-000635-15 Sponsor Protocol Number: 307970 Start Date*: 2005-09-07
    Sponsor Name:Schering AG
    Full Title: Randomized, multicentre, prospective, two-arm, open-label Phase II study to investigate the efficacy and safety of two ZK219477 i.v. infusions (3-hour infusion of 16mg/m2 versus 0.5-hour infusion o...
    Medical condition: Recurrent ovarian cancer
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-004905-27 Sponsor Protocol Number: CBD VP 132/05 Start Date*: 2008-02-01
    Sponsor Name:Dstl
    Full Title: Pharmacokinetic Interactions between Ciprofloxacin and Chloroquine / Proguanil Prophylaxis
    Medical condition: Chloroquine/proguanil is used for malaria chemoprophylaxis in areas where chloroquine-resistant Plasmodium falciparum malaria is prevalent, except in regions of Africa where chloroquine/proguanil i...
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-002702-63 Sponsor Protocol Number: 2006RD003 Start Date*: 2007-03-08
    Sponsor Name:South Manchester University Hospital NHS Trust
    Full Title: Does oral Ranitidine improve magnetic resonance cholangio-pancreatogram images allowing clinically useful improvement?
    Medical condition: Image quality improvement in Magnetic Resonance Cholangio-Pancreatogram scans
    Disease: Version SOC Term Classification Code Term Level
    8.1 10058641 Nuclear magnetic resonance imaging abdominal LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-006424-18 Sponsor Protocol Number: EC/2006/117/PGMS Start Date*: 2007-03-01
    Sponsor Name:University of Surrey
    Full Title: THE EFFECT OF RIMONABANT ON ENERGY EXPENDITURE, FATTY ACID METABOLISM, TRIACYLGLYCEROL METABOLISM AND BODY FAT DISTRIBUTION
    Medical condition: Obesity
    Disease: Version SOC Term Classification Code Term Level
    8.1 10029883 Obesity LLT
    Population Age: Adults Gender: Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2005-001384-60 Sponsor Protocol Number: C2380329 Start Date*: 2005-07-14
    Sponsor Name:GlaxoSmithKline Consumer Healthcare
    Full Title: An exploratory, observational cohort study investigating commercially available treatments which may reduce the scab stage of recurrent herpes labialis
    Medical condition: Recurrent herpes labialis (RHL)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-005227-42 Sponsor Protocol Number: PM1108357 Start Date*: 2007-08-30
    Sponsor Name:GlaxoSmithKline Research & Development Ltd
    Full Title: A double-blind, placebo-controlled, parallel study to evaluate the effects of GW-856553 on endothelial function/ vascular compliance in subjects with dyslipidaemia.
    Medical condition: GW-856553 is under development as a potential anti-atherosclerosis agent for reduction of major cardiovascular events in high risk patient populations
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-000106-24 Sponsor Protocol Number: RAA2006/004 Start Date*: 2006-06-26
    Sponsor Name:Kings College London (IOP)
    Full Title: Using genotype to tailor prescribing of nicotine replacement therapy: a randomised controlled trial assessing impact upon adherence
    Medical condition: Smoking addiction
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-005956-34 Sponsor Protocol Number: 0822-011 Start Date*: 2007-03-14
    Sponsor Name:Merck Sharp & Dohme Ltd
    Full Title: A Phase IIa Randomized, Placebo-Controlled Clinical Trial to Study the Safety and Efficacy of MK-0822 in Patients with Osteoarthritis
    Medical condition: Osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    8.1 10031161 Osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
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    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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