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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44341   clinical trials with a EudraCT protocol, of which   7370   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,341 result(s) found. Displaying page 157 of 2,218.
    EudraCT Number: 2007-006523-12 Sponsor Protocol Number: 19521952 Start Date*: 2009-08-12
    Sponsor Name:Julio Bobes
    Full Title: Mejora de la efectividad de los tratamientos de mantenimiento con naltrexona en adictos a opiáceos con la adicción de buprenorfina sublingual. Improvement of naltrexone maintenance treatment effec...
    Medical condition: Dependencia de opiáceos. Opiate dependence.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10012346 Dependence on opiates LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-005300-41 Sponsor Protocol Number: IC-DEL Start Date*: 2008-05-27
    Sponsor Name:University Medical Center Utrecht
    Full Title: Rivastigmine for delirium in Intensive Care patients, a double-blind, randomised, placebo-controlled, multi-center add-on trial
    Medical condition: Delirium
    Disease: Version SOC Term Classification Code Term Level
    9.1 10012218 Delirium LLT
    9.1 10012220 Delirium due to a general medical condition LLT
    9.1 10012226 Delirium, cause unknown LLT
    9.1 10013758 Drug-induced delirium LLT
    9.1 10012218 Delirium PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-005302-44 Sponsor Protocol Number: IPR110982 Start Date*: 2008-02-07
    Sponsor Name:GlaxoSmithKline Research & Development Limited
    Full Title: A randomised, double blind, 2-way crossover trial of 8 days repeat dosing with intranasal GSK256066 and azelastine hydrochloride in the Vienna Challenge Chamber in subjects with seasonal allergic r...
    Medical condition: Seasonal allergic rhinitis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10039776 Seasonal allergic rhinitis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2006-000799-33 Sponsor Protocol Number: 001 Start Date*: 2007-06-22
    Sponsor Name:Universitätsklinikum Essen
    Full Title: A Study of the efficacy and safety of Rizatriptan 10 mg PRD in the treatment of acute migraine in patients with non satisfactory response to previous pharmacologic treatment
    Medical condition: acute migraine
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-001969-15 Sponsor Protocol Number: 266-03/06 (AVT-02/2/DER/01) Start Date*: 2008-05-13
    Sponsor Name:Avontec GmbH
    Full Title: A multicenter, randomized, double-blind, placebo-controlled, intraindividual-comparison phase IIa trial to evaluate the efficacy and safety of 2% AVT-02 UE ointment in the topical treatment of mild...
    Medical condition: atopic dermatitis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003639 Atopic dermatitis LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-002410-35 Sponsor Protocol Number: 10 0330 02 - 0486 Start Date*: 2006-12-11
    Sponsor Name:Almirall Hermal GmbH
    Full Title: Double-blind, double-dummy, randomized, placebo-controlled, five-armed, multi-centre phase II/III study to evaluate the efficacy and safety of different concentrations of isotretinoin versus doxycy...
    Medical condition: Patients aded 18 and older suffering from papulopustular rosacea (subtype II) or moderate phymateous rosacea (moderate subtype III) with a minimum grade 4 in the 'Global physicians's assessment sco...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-004665-42 Sponsor Protocol Number: ST 200 DS 05-002 Start Date*: 2006-03-17
    Sponsor Name:SIGMA-TAU
    Full Title: Evaluation of the efficacy and tollerability of long-term somministration of Acetyl-l-carnitine in the treatment of HIV related lipodystrophy.Parallel group, randomized, double blind, controlled ve...
    Medical condition: HIV related LIPODYSTROPHY.
    Disease: Version SOC Term Classification Code Term Level
    6.1 10061624 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2005-004672-20 Sponsor Protocol Number: SYR-322-OLE-012 Start Date*: 2006-04-24
    Sponsor Name:Takeda Global Research & Development Center, Inc.,
    Full Title: A Long-Term, Open-Label Extension Study to Investigate the Long-Term Safety of SYR110322 (SYR-322) in Subjects with Type 2 Diabetes
    Medical condition: Type II diabetes mellitus.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) EE (Completed) SK (Completed) LV (Completed)
    Trial results: View results
    EudraCT Number: 2006-004290-97 Sponsor Protocol Number: ACCILTRA1 Start Date*: 2008-12-19
    Sponsor Name:Charité Universitätsmedizin Berlin, Department of Dermatology and Allergy
    Full Title: A Single-Centre, Open Label Study of the Safety and Tolerability of Rilonacept in Subjects Living in Germany with Muckle-Wells Syndrome (MWS), a Cryopyrin-Associated Periodic Syndrome, or Schnitzle...
    Medical condition: The medical condition to be investigated was first described by Muckle and Wells 1962. The Muckle-Wells syndrome (MWS) is rare and characterized by chronic recurrent urticaria, periodic arthritis, ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-004292-35 Sponsor Protocol Number: 06NB37 Start Date*: 2007-03-08
    Sponsor Name:Kings College Hospital NHS Foundation Trust
    Full Title: A pillot study to examine the safety and efficacy of intravitreal ranubizimab/dexamethasone administration and oral minocycline in addition to Visudyne (verteporfin) photdynamic therapy for subfove...
    Medical condition: Age related macular degeneration
    Disease: Version SOC Term Classification Code Term Level
    9.1 10064930 Age-related macular degeneration LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-000477-29 Sponsor Protocol Number: GPA02 Start Date*: 2006-05-11
    Sponsor Name:Sanofi Pasteur SA
    Full Title: Safety and immunogenicity of an intramuscular, inactivated, split-virion, pandemic influenza A/H5N1 vaccine in adults and the elderly.
    Medical condition: Vaccination of adults (18-60 years) and elderly (>60 years) with pandemic flu H5N1 vaccine.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-000497-80 Sponsor Protocol Number: H7U-MC-IDAV Start Date*: 2007-07-27
    Sponsor Name:Eli Lilly and Company Ltd
    Full Title: A Phase 3, Open-Label, Parallel-Group Study to Evaluate the Efficacy of Preprandial Human Insulin Inhalation Powder (HIIP) Compared to Preprandial Injectable Insulin in Patients with Type 1 Diabete...
    Medical condition: Male or female nonsmoking patients 18 years of age or older who have had type 1 diabetes mellitus for at least 24 months at study entry and are taking at least 2 or 3 preprandial injections per day...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) DE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2006-000506-22 Sponsor Protocol Number: DRI6624 Start Date*: 2006-05-24
    Sponsor Name:Sanofi aventis recherche & développement
    Full Title: A randomized, double-blind, triple-dummy, dose-ranging study, including an active control of unfractionated heparin and eptifibatide, to evaluate the clinical efficacy and safety of otamixaban, in ...
    Medical condition: Coronary desease in patients with non-ST elevation acute coronary syndrome and planned early invasive strategy
    Disease: Version SOC Term Classification Code Term Level
    8.1 10051592 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) AT (Completed) DK (Completed) DE (Completed) SK (Completed) HU (Completed) FI (Completed) EE (Completed) IT (Completed) PT (Completed) GR (Completed)
    Trial results: View results
    EudraCT Number: 2005-004051-35 Sponsor Protocol Number: INSTEM_HHU_2005 Start Date*: 2006-09-01
    Sponsor Name:University Hospital Düsseldorf
    Full Title: Intramyocardial Application of Stem Cells in combination with transmyocardial Laser Revascularisation (TMLR) in CABG Patients
    Medical condition: Other forms of chronic ischaemic heart disease
    Disease: Version SOC Term Classification Code Term Level
    70 10032058 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-004389-15 Sponsor Protocol Number: STH14192 Start Date*: 2007-04-05
    Sponsor Name:Sheffield Teaching Hospitals NHS Foundation Trust
    Full Title: The use of Single dose intravenous paracetamol "Perfalgan" in Early extubation cardiac surgery
    Medical condition: Extubation time following coronary artery bypass surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2004-001225-16 Sponsor Protocol Number: 3001077 Start Date*: 2004-10-28
    Sponsor Name:Orion Pharma
    Full Title: Survival of patients with acute heart failure in need of intravenous inotropic support; a multicentre parallel- group, randomised, double- blind, double- dummy study of levosimendan versus dobutami...
    Medical condition: Acutely decompensated heart failure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2007-002819-99 Sponsor Protocol Number: Pr BOUAZIZ - PSS 2007 Start Date*: 2007-12-18
    Sponsor Name:Centre Hospitalier Universitaire de Nancy
    Full Title: L’administration d’ondansetron dans le cadre d’une prophylaxie des nausées et vomissements postopératoires réduirait-il l’effet analgésique du paracétamol ?
    Medical condition: analgésie But de l'étude : évaluer cliniquement l’action inhibitrice de l’ondansetron administré en prophylaxie des nausées et vomissements postopératoires sur l’effet analgésique du paracétamol en...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10021415 Immediate postoperative analgesia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-002662-19 Sponsor Protocol Number: 20060111 Start Date*: 2006-10-23
    Sponsor Name:Amgen Inc.
    Full Title: ADVANCE - A Randomized Study to Evaluate the Effects of Cinacalcet Plus Low Dose Vitamin D on Vascular Calcification in Subjects with Chronic Kidney Disease (CKD) Receiving Hemodialysis
    Medical condition: Secondary hyperparathyroidism (HPT) in subjects with chronic kidney disease (CKD) receiving hemodialysis.
    Disease: Version SOC Term Classification Code Term Level
    8.1 10020708 Hyperparathyroidism secondary LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) HU (Completed) DE (Completed) IT (Completed) PT (Completed)
    Trial results: View results
    EudraCT Number: 2006-002669-38 Sponsor Protocol Number: 0822-016 Start Date*: 2006-12-07
    Sponsor Name:Merck & Co Inc.
    Full Title: A Phase II Study to Assess the Safety, Tolerability, and Efficacy of MK-0822 (Cathepsin-K Inhibitor) in the Treatment of Women with Breast Cancer and Established Bone Metastases (MBD)
    Medical condition: Metastatic Bone Disease (MBD)
    Disease: Version SOC Term Classification Code Term Level
    8.1 10027452 Metastases to bone LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DE (Completed) NO (Completed) DK (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2005-005998-29 Sponsor Protocol Number: ICGHCL 2004 Start Date*: 2004-09-26
    Sponsor Name:AZIENDA OSPEDALIERA SENESE
    Full Title: FIVE- VERSUS SEVEN-DAY SUBCUTANEOUS ADMINISTRATION OF CLADRIBINE IN HAIRY CELL LEUKEMIA
    Medical condition: Patients with histologically verified HCL classical HCL presence of HCs in the bone marrow and in the peripheral blood detected by positive TRAP staining and positive DBA44 and/or co-expression o...
    Disease: Version SOC Term Classification Code Term Level
    10019053 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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