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Clinical trials for Paracetamol

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44349   clinical trials with a EudraCT protocol, of which   7376   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    436 result(s) found for: Paracetamol. Displaying page 2 of 22.
    « Previous 1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2015-004217-24 Sponsor Protocol Number: s58396 Start Date*: 2015-11-30
    Sponsor Name:UZ Leuven
    Full Title: Pharmacokinetic study of paracetamol in patients over 80 years old admitted to an acute geriatric ward
    Medical condition: Pyrexia Pain
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2013-004908-20 Sponsor Protocol Number: PARAMRI Start Date*: 2013-12-23
    Sponsor Name:UZ Brussel [...]
    1. UZ Brussel
    2. UZ Brussel
    Full Title: Cerebral effect of paracetamol measured by f-MRI
    Medical condition: healthy volunteers
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2015-003177-14 Sponsor Protocol Number: IBUPAR-Trial Start Date*: 2016-04-06
    Sponsor Name:
    Full Title: Paracetamol versus ibuprofen in preterm infants with a hemodynamically significant patent ductus arteriosus: a randomized clinical trial.
    Medical condition: Persistent ductus arteriosus haemodynamically significant
    Disease:
    Population Age: Preterm newborn infants, Under 18 Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-005086-20 Sponsor Protocol Number: CHDR1117 Start Date*: 2011-11-22
    Sponsor Name:Centre for Human Drug Research (CHDR)
    Full Title: Effects of paracetamol on nociception in adolescents.
    Medical condition: Nociceptive pain (disorders)
    Disease:
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2011-000923-33 Sponsor Protocol Number: HepB/APAP/2011 Start Date*: 2011-07-14
    Sponsor Name:Rijksinstituut voor Volksgezondheid en Milieu (RIVM)
    Full Title: Effects of paracetamol use on the immune response after hepatitis B vaccination
    Medical condition: No medical conditions will be studied. The association between timing of the use of paracetamol during hepatitis B vaccination and the development of an antibody response will be studied in student...
    Disease: Version SOC Term Classification Code Term Level
    13.1 10042613 - Surgical and medical procedures 10054181 Hepatitis B immunization LLT
    13.1 10022891 - Investigations 10033765 Paracetamol normal LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-000427-26 Sponsor Protocol Number: Start Date*: 2009-06-25
    Sponsor Name:Queen Victoria Hospital NHS Foundation Trust
    Full Title: A Comparison of Pre−Medication with Oral Paracetamol versus Intravenous Paracetamol Given at Time of Induction for Postoperative Analgesia Following Wisdom Tooth Extraction
    Medical condition: Pain post wisdom tooth extraction
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-005575-14 Sponsor Protocol Number: R-01270-A015 Start Date*: 2006-08-08
    Sponsor Name:Baxter R&D Europe S.C.R.L
    Full Title: A randomized, double-blind, placebo-controlled, single-dose, parallel-group comparison of the analgesic efficacy, safety and local tolerability of intravenous paracetamol 1% solution Bioren (test),...
    Medical condition: Post-surgical dental pain after removal of one or more impacted 3rd mandibular molar(s), associated with moderate to severe pain.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2018-002226-22 Sponsor Protocol Number: 2.0 Start Date*: 2019-04-30
    Sponsor Name:Medical University of Vienna
    Full Title: The Impact of Target Temperature Management on Drug Metabolism
    Medical condition: Patients after successful cardiopulmonary resuscitation who undergo target temperature management for 24h hours
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2018-000565-36 Sponsor Protocol Number: 38/2018 Start Date*: 2018-06-05
    Sponsor Name:University of Oulu
    Full Title: Paracetamol and ibuprofen/indomethacin in closing persistent ductus arteriosus
    Medical condition: Patent ductus arteriosus of a premature infant
    Disease:
    Population Age: Preterm newborn infants, Under 18 Gender: Male, Female
    Trial protocol: FI (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2018-000388-10 Sponsor Protocol Number: WADA_17C09 Start Date*: 2019-06-11
    Sponsor Name:Daniel Sanabria
    Full Title: Clinical trial on the effects of the tramadol and paracetamol on physical, cognitive and brain performance during cycling
    Medical condition: Sports doping
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-000197-38 Sponsor Protocol Number: AC15006 Start Date*: 2016-08-04
    Sponsor Name:University of Edinburgh [...]
    1. University of Edinburgh
    2. NHS Lothian
    Full Title: A double blind randomised parallel group trial of paracetamol versus placebo in conjunction with strong opioids for cancer related pain.
    Medical condition: Cancer related pain.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004867 10069398 Breakthrough cancer pain LLT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10058019 Cancer pain PT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10058019 Cancer pain PT
    Population Age: Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2020-005123-36 Sponsor Protocol Number: PARASTOP Start Date*: 2021-07-05
    Sponsor Name:Oslo University Hospital
    Full Title: A randomized, double-blind, parallel-group non-inferiority phase III withdrawal trial of paracetamol versus placebo in conjunction with opioids for moderate to severe cancer-related pain
    Medical condition: Adult patients with metastatic cancer disease, cancer-related pain treated with regular strong opioids, receiving paracetamol (1 gram three or four times a day) and with average pain intensity past...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2004-002137-39 Sponsor Protocol Number: V1 25/07/04 Start Date*: 2004-09-17
    Sponsor Name:
    Full Title: A randomised controlled trial of the combined use of paracetamol and ibuprofen to treat febrile children
    Medical condition: Fevers in childhood not asscoaited with severe disease in the immunocompenetent or fever in the immunocompromised host.
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2005-001639-30 Sponsor Protocol Number: TramaPara8405 Start Date*: 2006-10-02
    Sponsor Name:Department of Anaesthesia&Intensive Care B, Vienna Medical University
    Full Title: Investigation of the antihyperalgesic effect of a combination of tramadol and paracetamol on primary and secondary hyperalgesia in an UV-B induced inflammatory skin pain model in healthy volunteers.
    Medical condition: This is a volunteer study in healthy volunteers.
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2009-014892-31 Sponsor Protocol Number: MAIVECMOPAIN Start Date*: 2009-11-10
    Sponsor Name:ErasmusMC - Sophia
    Full Title: Morphine intravenous vs. Paracetamol intravenous in children on ECMO
    Medical condition: Patients treated with Extra Corporal Membrane Oxygenation (ECMO) receive morphine as standardised analgesic drug. Morphine is associated with several side effects. In these patients a non-opioid dr...
    Disease:
    Population Age: Preterm newborn infants, Newborns, Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-002213-12 Sponsor Protocol Number: I10 005 Start Date*: Information not available in EudraCT
    Sponsor Name:CHU de Limoges
    Full Title: Paracetamol and setrons : drug interactions in the management of pain after tonsillectomy in children
    Medical condition: Pain
    Disease: Version SOC Term Classification Code Term Level
    14.0 10022117 - Injury, poisoning and procedural complications 10049749 Post procedural pain LLT
    14.0 10022117 - Injury, poisoning and procedural complications 10064882 Procedural pain PT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: View results
    EudraCT Number: 2013-000247-58 Sponsor Protocol Number: PKZW-NZW201301 Start Date*: 2013-09-30
    Sponsor Name:KU Leuven Departement Ontwikkeling en Regeneratie
    Full Title: Pharmacokinetics of drugs used by pregnant women (paracetamol/macrolide antibiotics): in vivo pharmacokinetic study of pregnant versus non-pregnant women.
    Medical condition: 1) Pregnant women who, due to medical indication, need to take one of the experimental drugs (paracetamol, azithromycin or erythromycin) in the second or third trimester of there pregnancy 2) The s...
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2006-004790-10 Sponsor Protocol Number: A2720382 Start Date*: 2007-06-06
    Sponsor Name:GlaxoSmithKline Consumer Healthcare
    Full Title: A Proof-of-Principle Analgesic Adjuvant Pilot Study in Post-Operative Dental Pain
    Medical condition: Analgesia induced by dental extraction
    Disease: Version SOC Term Classification Code Term Level
    8.1 10044049 Dental pain and sensation disorders HLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2018-000138-37 Sponsor Protocol Number: FMLD-HUNGRIA-2-42_FIII Start Date*: 2018-04-25
    Sponsor Name:Laboratorios Farmalíder S.A.
    Full Title: PHASE III CLINICAL TRIAL FOR THE EVALUATION OF THE EFFICACY AND SAFETY OF A PARACETAMOL + IBUPROFEN COMBINATION IN PATIENTS WITH PRIMARY DYSMENORRHOEA
    Medical condition: DYSMENORRHOEA
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-002668-42 Sponsor Protocol Number: TRA-IV-17-1 Start Date*: 2017-10-11
    Sponsor Name:Laboratoires SMB S.A.
    Full Title: A randomised, interventional, double blind, crossover, controlled study to assess the effect of the administration of paracetamol on tramadol adverse events.
    Medical condition: healthy volunteers (symptomatic treatment of pain)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BG (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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