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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44338   clinical trials with a EudraCT protocol, of which   7368   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,338 result(s) found. Displaying page 2,186 of 2,217.
    EudraCT Number: 2016-004390-41 Sponsor Protocol Number: BLU-667-1101 Start Date*: 2018-03-13
    Sponsor Name:Blueprint Medicines
    Full Title: A Phase 1/2 Study of the Highly-selective RET Inhibitor, BLU-667, in Patients with Thyroid Cancer, Non-Small Cell Lung Cancer (NSCLC) and Other Advanced Solid Tumors
    Medical condition: Thyroid Cancer, Non-Small Cell Lung Cancer (NSCLC) and Other Advanced Solid Tumors
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004864 10066914 Thyroid tumor LLT
    20.0 100000004864 10025044 Lung cancer LLT
    21.1 100000004864 10065252 Solid tumor LLT
    21.1 100000004864 10029514 Non-small cell lung cancer NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) DE (Completed) NL (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2016-002778-11 Sponsor Protocol Number: E7080-G000-218 Start Date*: 2017-06-12
    Sponsor Name:Eisai Ltd
    Full Title: A Randomized, Open-label (formerly Double-blind), Phase 2 Trial to Assess Safety and Efficacy of Lenvatinib at Two Different Starting Doses (18 mg vs. 14 mg QD) in Combination with Everolimus (5 mg...
    Medical condition: Advanced renal cell carcinoma
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10038389 Renal cancer PT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10038409 Renal cell carcinoma NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) GB (GB - no longer in EU/EEA) NL (Completed) GR (Completed) FI (Completed) PL (Completed) ES (Ongoing) PT (Completed) IT (Completed) RO (Ongoing)
    Trial results: View results
    EudraCT Number: 2004-000645-37 Sponsor Protocol Number: 20030205 Start Date*: 2004-09-02
    Sponsor Name:Amgen Inc
    Full Title: A Randomised, Multi-Center, Double-Blind, Placebo-Controlled, Dose-Finding Study of AMG 114 Administered by Subcutaneous Injection for the Treatment of Anemia in Subjects With Non-myeloid Malignanc...
    Medical condition: Treatment of anemia in cancer subjects with non-myeloid malignancies receiving multicycle chemotherapy
    Disease: Version SOC Term Classification Code Term Level
    7.0 10049105 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) ES (Ongoing) AT (Completed) DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-002369-19 Sponsor Protocol Number: 11.8.2004 Start Date*: 2004-10-12
    Sponsor Name:Hvidovre Hospital [...]
    1. Hvidovre Hospital
    2. Hvidovre Hospital
    Full Title: Behandling af savlen hos børn med cerebral parese ved anvendelse af botulinum toksin i spytkirtler
    Medical condition: Børn med cerebral parese har ofte problemer med savlen, primært på grund af nedsat synkefunktion.
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-000647-24 Sponsor Protocol Number: SKF 0411 Start Date*: 2004-08-16
    Sponsor Name:Dept. Oncology, Aarhus University Hospital
    Full Title: Fase II undersøgelse af kemo-embolisering af lokal avancerede primære hepatocellulære carcinomer
    Medical condition:
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-001103-35 Sponsor Protocol Number: NSGO -EC - 0302 Start Date*: 2004-08-20
    Sponsor Name:Nordic Society for Gynecologic Oncology
    Full Title: Exemestane in Advanced or Recurrent Endometrial Carcinoma. A multicentre non-randomized Phase II study
    Medical condition: Advanced or recurrent endometrial carcinoma
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-002623-41 Sponsor Protocol Number: endo 220604 Start Date*: 2004-09-10
    Sponsor Name:Anders Nyboe Andersen, klinikchef, dr. med., Fertilitetsklinikken afsnit 4071, Rigshospitalet
    Full Title: Anvendelse af aromatase-inhibitor (Arimidex) i kombination med GnRH agonist (Zoladex) som forbehandling til IVF hos patienter med ovariel endometriose
    Medical condition: endometriosis ovarii
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-003887-31 Sponsor Protocol Number: 2004/116 Start Date*: 2004-12-09
    Sponsor Name:Klinisk Farmakologisk Center og Med. Afd. M, Århus Sygehus, NBG
    Full Title: "Farmakodynamiske egenskaber af to langtidsvirkende insulinanaloger i sammenligning med NPH insulin"
    Medical condition: Healthy subjects.
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-003796-37 Sponsor Protocol Number: MELMIS Start Date*: 2005-01-26
    Sponsor Name:Dept. of surg.gastroent., Gentofte University Hospital, Copenhagen
    Full Title: Effekt af melatonin på forekomsten af postoperativ træthed og søvnforstyrrelser efter laparoskopisk kolecystektomi. En randomiseret dobbelt-blindet placebo kontrolleret undersøgelse.
    Medical condition: postoperativ fatigue og søvnforstyrrelser
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-003595-11 Sponsor Protocol Number: 2004-06-DP-119-RKF-25 Start Date*: 2005-03-18
    Sponsor Name:Canadian Cardiovascular Collaboration, Population Health Research Institute, McMaster University
    Full Title: PeriOperative ISchemic Evaluation study
    Medical condition: Perioperative cardiac events frequently complicate non-cardiac surgery resulting in significant morbidity, mortality and cost. There is no clear evidence from RCTs on how to lower perioperative ca...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed) ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-003777-90 Sponsor Protocol Number: 93687386 Start Date*: 2005-10-28
    Sponsor Name:Organisation name was not entered [...]
    1. Organisation name was not entered
    2. Anæstesiklinikken, Frederiksberg Hospital
    Full Title: Har magnesiumsulfat (MgSO4) en smertelindrende effekt ved total hoftealloplastik?
    Medical condition: Ptt. som skal have en total hoftealloplastik.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-002653-31 Sponsor Protocol Number: VF20040171 Start Date*: 2004-11-25
    Sponsor Name:Odense University hospital
    Full Title: CAPHI. Profylactic effect of Ca2+ sensitizer versus phosphodiesterase inhibitor infusion at CAGB patients with preoperative low ejection fraction. A prospective randomised clinical trial.
    Medical condition: Perioperative use of Milrinon to CAGB patients has shown to reduce postoperative complications. Levosimendan improves cardiac performance without interfering with the calcium turnover and there by ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-004801-11 Sponsor Protocol Number: 04-081 Start Date*: 2005-02-14
    Sponsor Name:Zealand Pharma A/S
    Full Title: A Phase II, Multicenter, Double-Blind, Efficacy, Safety, and Tolerability Study of ZP120 Administered as Short Term I.V. Infusion as Add-On Therapy in Patients with Subacute Decompensated Chronic H...
    Medical condition: Subacute decompensated chronic heart failure NYHA Class III-IV
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-004139-74 Sponsor Protocol Number: PB1 Start Date*: 2005-04-20
    Sponsor Name:Neurologisk afdeling F
    Full Title: Parkinson’s Disease: PET scan and evaluation of memantines pharmacological effect. (Parkinsons sygdom bedømt med PET skanning, herunder memantins farmakologiske effekt.)
    Medical condition: Parkinson's Disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-004670-88 Sponsor Protocol Number: 4975-2-007-2 Start Date*: 2005-05-23
    Sponsor Name:AlgoRx Pharmaceuticals, Inc.
    Full Title: A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Analgesic Efficacy, Safety and Tolerability of ALGRX 4975 in Subjects after Inguinal Hernia Repair
    Medical condition: Inguinal Hernia
    Disease: Version SOC Term Classification Code Term Level
    7.1 10022020 LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-004452-39 Sponsor Protocol Number: PDT-01-2004 Start Date*: 2005-01-24
    Sponsor Name:Christel B. Lajer, Dep. of Otolaryngology head and neck surgery, Rigshospitalet
    Full Title: Photodynamic therapy as palliative treatment for recurrent squamous cell carcinom of the head and neck region
    Medical condition: Recurrent squamous cell carcinoma of the head and neck Region
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-001086-34 Sponsor Protocol Number: IGG-PRINTO-001 Start Date*: 2005-10-21
    Sponsor Name:Istituto Giannina Gaslini-PRINTO
    Full Title: A randomised trial of 6 months versus 12 months withdrawal of methotrexate in patiebts with juvenile idiopathic arthritis in clinical remission.Ensayo aleatorizado de retirada de Metotrexate a los ...
    Medical condition: The present study was designed for the follow up of two groups of patients with JIA, in whom remission was achieved using MTX. In group 1 treatment with MTX will be discontinued as early as 6 month...
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: ES (Ongoing) IT (Completed) DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-000541-11 Sponsor Protocol Number: P-7282 Start Date*: 2005-03-31
    Sponsor Name:Slidgigtinstituttet A/S
    Full Title: Glukosaminsulfat og hyperkolesterolæmi
    Medical condition: Osteoarthritis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-000309-75 Sponsor Protocol Number: Start Date*: 2005-08-26
    Sponsor Name:Christian Geisler, Rigshospitalet, dept. Haematology 4042
    Full Title: HOVON 68 CLL: A randomized phase III study in prevously untreated patients with biological high risk CLL: Fludarabine + cyclophosphamide (FC) versus FC + low-dose alemtuzumab.
    Medical condition: Chronic lymphocytic leukaemia (CLL) in biological high-risk group: Unmutated and/or with deletion 17p and/or deletion 11q and/or trisomy 12.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed) SE (Ongoing) FI (Completed) BE (Completed) CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-004908-21 Sponsor Protocol Number: D0170C00006 Start Date*: 2005-02-28
    Sponsor Name:AstraZeneca AB
    Full Title: A Phase II, double-blind, randomized, cross-over, international, multicentre study to evaluate the analgesic efficacy of 3 weeks oral administration of AZD4282 300 mg b.i.d. compared with placebo i...
    Medical condition: Diagnosis of postherpetic neuralgia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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