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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44380   clinical trials with a EudraCT protocol, of which   7392   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,380 result(s) found. Displaying page 24 of 2,219.
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    EudraCT Number: 2008-000928-71 Sponsor Protocol Number: GOIRC02/2008-TWIST Start Date*: 2008-11-14
    Sponsor Name:GRUPPO ONCOLOGICO ITALIANO DI RICERCA
    Full Title: “TWIST”. RANDOMIZED PROSPECTIVE PHASE II STUDY OF TEMSIROLIMUS WITH OR WITHOUT LOW-DOSE INTERFERON ALPHA IN METASTATIC NON-CLEAR RENAL CELL CARCINOMA: GOIRC STUDY 02/2008
    Medical condition: Patients with advanced non-clear Cell Renal Carcinoma.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10050513 Metastatic renal cell carcinoma LLT
    9.1 10038458 Renal granular cell carcinoma PT
    9.1 10038414 Renal cell carcinoma stage IV PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-000942-29 Sponsor Protocol Number: 6520-0650-13 Start Date*: 2008-06-23
    Sponsor Name:Medice Arnzneimittel Pütter GmbH & Co. KG
    Full Title: Quality assurance of methylphenidate administration in adults with ADHS
    Medical condition: Aufmerksamkeitsdefizit/Hyperaktivitätsstörungen (ADHS) bei Erwachsenen
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-000259-33 Sponsor Protocol Number: 06-AnIt-06 Start Date*: 2007-08-16
    Sponsor Name:Department of Anesthesiology and Intensive Care, University Hospital Münster
    Full Title: Perioperative protective effects of lidocaine - clinical study on the route and timing of administration
    Medical condition: patients, scheduled for major elective colorectal surgery
    Disease: Version SOC Term Classification Code Term Level
    14.0 10042613 - Surgical and medical procedures 10040668 Sigmoid hemicolectomy LLT
    14.0 10042613 - Surgical and medical procedures 10009879 Colectomy total PT
    14.0 10042613 - Surgical and medical procedures 10059848 Proctocolectomy PT
    14.0 10042613 - Surgical and medical procedures 10019460 Hemicolectomy LLT
    14.0 10042613 - Surgical and medical procedures 10039153 Right hemicolectomy LLT
    14.0 10042613 - Surgical and medical procedures 10024107 Left hemicolectomy LLT
    14.0 10042613 - Surgical and medical procedures 10063950 Ileocolectomy PT
    14.0 10042613 - Surgical and medical procedures 10042609 Surgery PT
    14.0 10042613 - Surgical and medical procedures 10061778 Colectomy PT
    14.0 10042613 - Surgical and medical procedures 10044083 Total colectomy LLT
    14.0 10042613 - Surgical and medical procedures 10009878 Colectomy partial LLT
    14.0 10042613 - Surgical and medical procedures 10009880 Colectomy transverse LLT
    14.0 10042613 - Surgical and medical procedures 10033684 Panproctocolectomy LLT
    14.0 10042613 - Surgical and medical procedures 10044447 Transverse colectomy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-000271-42 Sponsor Protocol Number: 11012007 Start Date*: 2007-05-08
    Sponsor Name:Matti Eskelinen
    Full Title: OKSIKODONIN ANALGEETTINEN PITOISUUS PLASMASSA YHDESSÄ PARASETAMOLIN 1g TAI 2g IV KANSSA ANNETTUNA MAHAKIRURGISILLA POTILAILLA
    Medical condition: Tutkimukseen otetaan 24 sappileikkaukseen tulevaa perustervettä aikuispotilasta.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10017641 Gallbladder disease LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-002542-38 Sponsor Protocol Number: CAEB071A2210 Start Date*: 2007-11-28
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A randomized, double blind, placebo controlled, parallel group design study to explore the efficacy, safety and tolerability of AEB071 in patients with active, moderate to severe ulcerative colitis.
    Medical condition: Ulcerative colitis
    Disease: Version SOC Term Classification Code Term Level
    14.0 10017947 - Gastrointestinal disorders 10045365 Ulcerative colitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended) DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-005254-68 Sponsor Protocol Number: GEL/TAMO-2006 Start Date*: 2007-04-13
    Sponsor Name:GEL/TAMO (Cooperative Spanish Group of Lymphoma/Autologous bone marrow transplant).
    Full Title: Treatment with R-MegaCHOP and early rescue with R-IFE and autologous stem cells transplant (ASCT) according response measured by positron emission tomography (PET) in patients with diffuse large B-...
    Medical condition: Diffuse Large B-Cell Lymphoma (DLBCL)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-005152-16 Sponsor Protocol Number: BV-2007/04 Start Date*: 2008-10-07
    Sponsor Name:OM Pharma SA
    Full Title: Multicentre, randomised, double-blind, placebo-controlled study of the efficacy and safety of Broncho-Vaxom in adults suffering from chronic rhinosinusitis
    Medical condition: Chronic rhinosinusitis
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10052106 Rhinosinusitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2007-005163-94 Sponsor Protocol Number: BAY81-8781/12946 Start Date*: 2010-10-08
    Sponsor Name:Bayer HealthCare AG
    Full Title: A prospective, randomized, verum controlled, open label, parallel group multi-center phase III clinical trial to demonstrate the superiority of 500 or 250 mg Aspirin® i.v. (BAY 81-8781) treatment v...
    Medical condition: Acute coronary syndrome (ACS)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10051592 Acute coronary syndrome PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-005164-27 Sponsor Protocol Number: 260981 Start Date*: 2008-02-22
    Sponsor Name:research office urology VUmc
    Full Title: Botulinum toxin A intravesical injections in the treatment of Bladder Pain Syndrome/ Interstitial Cystitis
    Medical condition: Interstitial Cystitis (IC) is a syndrome characterized by bladder pain associated with urgency, frequency, nocturia, dysuria and sterile urine. The patho-physiology remains largely unclear. No univ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-005169-36 Sponsor Protocol Number: NKV110721 Start Date*: 2008-02-07
    Sponsor Name:GlaxoSmithKline Research and Development Limited
    Full Title: NKV110721, A Study of Single Dose Intravenous Casopitant in Combination with Ondansetron and Dexamethasone for the Prevention of Oxaliplatin-Induced Nausea and Vomiting
    Medical condition: Prevention of nausea and vomiting due to first cycle of oxaliplatin based chemotherapy in patients with colorectal cancer receiving a combination with 5-fluorouracil and leucovorin, or in combinati...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) CZ (Completed) DE (Completed) HU (Completed) IT (Completed) SK (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2005-002494-75 Sponsor Protocol Number: CL3-12911-018 Start Date*: 2006-04-26
    Sponsor Name:Institut de Recherches Internationales Servier
    Full Title: The efficacy and safety of two doses of strontium ranelate (1g and 2g per day) versus placebo administered orally for 3 years in the treatment of knee osteoarthritis. A prospective multicentre, int...
    Medical condition: Osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    7.0 10031161 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed) BE (Completed) GB (Completed) ES (Completed) IT (Completed) DK (Completed) PT (Completed) LT (Completed) EE (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2007-000971-41 Sponsor Protocol Number: GGCP032/07 Start Date*: 2007-07-03
    Sponsor Name:Grupo Gallego de Cáncer de Pulmón
    Full Title: Estudio fase II de bevacizumab en combinación con vinorelbina y cisplatino, como tratamiento de primera línea de pacientes con cáncer de pulmón no microcítico,no epidermoide, estadio IIIB con derra...
    Medical condition: Cáncer de pulmón no microcítico(CPNM), no epidermoide, estadio IIIB con derrame pleural o IV / on-small cell, non-squamous lung cancer, stage IIIb with pleural effusion or stage IV.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10029522 Non-small cell lung cancer stage IV PT
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10029521 Non-small cell lung cancer stage IIIB PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-002218-13 Sponsor Protocol Number: 25289 Start Date*: 2004-11-09
    Sponsor Name:INDUSTRIA FARMACEUTICA SERONO
    Full Title: A phase III, multicenter, randomized, open, comparative study to evaluate if the addition of r-hLH (Luveris) ti FSH from day 8 of ovarian stimulation is able to decrease total FSH dose and to impro...
    Medical condition: Reduction of the FSH dose needed to obtain/retrieve each oocyte after administration of Luveris to FSH at day 8 of ovarian stimulation.
    Disease: Version SOC Term Classification Code Term Level
    6.1 10021928 PT
    Population Age: Adults Gender: Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2007-004553-29 Sponsor Protocol Number: ML21287 Start Date*: 2007-10-23
    Sponsor Name:Roche
    Full Title: Essai en ouvert, randomisé et multicentrique évaluant l’efficacité et la tolérance de l’association de l’Enfuvirtide en cure d’induction de 3 mois à un traitement optimisé (TO) comprenant au moins ...
    Medical condition: Patients séropositifs VIH-1 en échec de lignes de traitements antirétroviraux antérieurs
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020161 HIV infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-000144-14 Sponsor Protocol Number: N01276 Start Date*: 2008-07-14
    Sponsor Name:UCB Inc
    Full Title: An international, double-blind, randomized, multi-center, parallel group, historical-control conversion to monotherapy study to evaluate the efficacy and safety of brivaracetam in subjects (≥ 16 to...
    Medical condition: Partial onset seizures with or without secondary generalization.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10015037 Epilepsy LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) CZ (Prematurely Ended) DE (Prematurely Ended) SE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-001913-41 Sponsor Protocol Number: C87085 Start Date*: 2007-12-12
    Sponsor Name:UCB Celltech
    Full Title: A phase IIIb, multinational, randomized, double-blind, placebo-controlled trial to assess the efficacy and safety of certolizumab pegol, a pegylated Fab' fragment of a humanized anti-TNF-alpha mono...
    Medical condition: Crohn`s disease
    Disease: Version SOC Term Classification Code Term Level
    9.1 10011401 Crohn's disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Prematurely Ended) HU (Completed) LV (Completed) BE (Completed) EE (Completed) IT (Completed) DE (Completed) CZ (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2005-003749-15 Sponsor Protocol Number: RES/0186/7211 Start Date*: 2006-02-02
    Sponsor Name:Merck, Sharp & Dohme-Clinical Pharmacology,Europe
    Full Title: Investigation of the effectiveness of oral lorazepam in managing preoperative dental anxiety in phobic dental patients-A pilot study
    Medical condition: Pre operative dental anxiety, in phobic dental patients.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2005-003750-10 Sponsor Protocol Number: NA Start Date*: 2005-09-12
    Sponsor Name:VästraGötaland
    Full Title: Growth hormone and androgens in the treatment of glucocorticoid induced protein catabolism
    Medical condition: Chronic treatment with glucocorticoids (GCs) regardless of indication leads to marked protein catabolism that causes substantial debilitation which includes muscle wasting, weakness, skin fragility...
    Disease:
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-005755-42 Sponsor Protocol Number: GEIS 15 Start Date*: 2008-01-28
    Sponsor Name:Grupo Español de Investigación en Sarcomas
    Full Title: ENSAYO CLÍNICO FASE II DE TRATAMIENTO NEOADYUVANTE CON IFOSFAMIDA A DOSIS ALTAS Y RADIOTERAPIA CONCOMITANTE EN SARCOMAS DE PARTES BLANDAS E IDENTIFICACION DE MARCADORES PREDICTORES DE RESPUESTA
    Medical condition: Sarcomas de Partes Blandas de tronco y extremidades
    Disease: Version SOC Term Classification Code Term Level
    9.1 10041299 Soft tissue sarcomas HLGT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-005777-57 Sponsor Protocol Number: NE-01 Start Date*: 2008-05-13
    Sponsor Name:Hospital Errikos Dunant- Department of Hematology
    Full Title: A comparative study of low molecular weight IV iron dextran (CosmoFer®) versus per os iron for the treatment of anaemia in patients with haematological malignancies receiving epoietin treatment
    Medical condition: Fe deficiency anaemia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10002034 Anaemia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Prematurely Ended)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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