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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44351   clinical trials with a EudraCT protocol, of which   7378   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,351 result(s) found. Displaying page 24 of 2,218.
    EudraCT Number: 2005-000192-17 Sponsor Protocol Number: GO-80, V1 18 Mar 05 Start Date*: 2005-05-18
    Sponsor Name:Barts & The London NHS Trust
    Full Title: Gemcitabine and Oxaliplatin in the treatment of locally advanced or metastatic transitional cell carcinoma of the urinary tract in patients with impaired renal function and patients who have progr...
    Medical condition: Locally advanced or metastatic transitional cell carcinoma of the urinary tract
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-001881-33 Sponsor Protocol Number: AEO-2007-01 Start Date*: 2007-05-21
    Sponsor Name:Medicinsk gastroenterologisk afdeling, Aalborg sygehus S.
    Full Title: Undersøgelse af opioiders effekt på eksperimentel hyperalgesi i spiserør og hud samt på en iskæmisk muskelmodel, inklusiv et eksplorativt studie af morfins ændringer i hjernens smerte processering.
    Medical condition:
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-004834-33 Sponsor Protocol Number: ROB 803-09-002 Start Date*: 2007-07-05
    Sponsor Name:OxyPharma AB
    Full Title: A Phase II, Randomised, Double-blind, International, Multicentre, Placebo-controlled, Dose-ranging, Parallel-group Study to Evaluate the Efficacy and Safety of Orally Administered Rob 803 when Adde...
    Medical condition: Rheumatiod Arthritis
    Disease: Version SOC Term Classification Code Term Level
    8.1 10039073 Rheumatoid arthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LT (Completed) LV (Completed) GB (Completed) BE (Completed) BG (Completed) PL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-004840-21 Sponsor Protocol Number: RISED_C_00935 Start Date*: 2007-04-23
    Sponsor Name:sanofi-aventis Netherlands B.V.
    Full Title: Bone Histomorphometry, Microarchitecture and Matrix Structure and Properties in Patients Receiving Long-term Risedronate Treatment
    Medical condition: The objective of this study is to collect data on bone histomorphometry, architecture, turnover and material properties from iliac crest biopsies taken from postmenopausal women after > 5 year rise...
    Disease: Version SOC Term Classification Code Term Level
    8.1 10031285 Osteoporosis postmenopausal LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2006-004849-42 Sponsor Protocol Number: 88/2006/O/Sper Start Date*: 2006-11-02
    Sponsor Name:AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI
    Full Title: Cetuximab + Irinotecano vs chemoterapia standard nel carcinoma colo-rettale avanzato pretrattato non resecabile esprimente EGFR
    Medical condition: carcinoma colo-rettale avanzato
    Disease: Version SOC Term Classification Code Term Level
    9.1 10010023 Colorectal neoplasms malignant HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2008-002002-19 Sponsor Protocol Number: MODAGE MO 169 Start Date*: 2008-06-11
    Sponsor Name:BIOCODEX
    Full Title: Effets du moclobémide sur le profil d'activation cérébrale de patients dépressifs âgés lors de tâches cognitives et émotionnelles, en référence à des sujets témoins. Etude ouverte, multicentrique, ...
    Medical condition:
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-005033-11 Sponsor Protocol Number: SRx-501-01 Start Date*: 2008-03-27
    Sponsor Name:CombinatoRx, Inc
    Full Title: A Comparison Of The Safety And Bioavailability Of Modified-Release Formulations Of Levodopa-Carbidopa In Subjects With Parkinson’s Disease
    Medical condition: Patients with Parkinson's Disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-000905-12 Sponsor Protocol Number: CCD-0802-PR-0029 Start Date*: 2008-08-20
    Sponsor Name:CHIESI
    Full Title: A single dose, randomized, double blind, double dummy, placebo controlled, three-period crossover clinical study, comparing the onset of relief from methacholine induced bronchoconstriction with ...
    Medical condition: Ashtma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003553 Asthma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-000928-71 Sponsor Protocol Number: GOIRC02/2008-TWIST Start Date*: 2008-11-14
    Sponsor Name:GRUPPO ONCOLOGICO ITALIANO DI RICERCA
    Full Title: “TWIST”. RANDOMIZED PROSPECTIVE PHASE II STUDY OF TEMSIROLIMUS WITH OR WITHOUT LOW-DOSE INTERFERON ALPHA IN METASTATIC NON-CLEAR RENAL CELL CARCINOMA: GOIRC STUDY 02/2008
    Medical condition: Patients with advanced non-clear Cell Renal Carcinoma.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10050513 Metastatic renal cell carcinoma LLT
    9.1 10038458 Renal granular cell carcinoma PT
    9.1 10038414 Renal cell carcinoma stage IV PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-000942-29 Sponsor Protocol Number: 6520-0650-13 Start Date*: 2008-06-23
    Sponsor Name:Medice Arnzneimittel Pütter GmbH & Co. KG
    Full Title: Quality assurance of methylphenidate administration in adults with ADHS
    Medical condition: Aufmerksamkeitsdefizit/Hyperaktivitätsstörungen (ADHS) bei Erwachsenen
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-000259-33 Sponsor Protocol Number: 06-AnIt-06 Start Date*: 2007-08-16
    Sponsor Name:Department of Anesthesiology and Intensive Care, University Hospital Münster
    Full Title: Perioperative protective effects of lidocaine - clinical study on the route and timing of administration
    Medical condition: patients, scheduled for major elective colorectal surgery
    Disease: Version SOC Term Classification Code Term Level
    14.0 10042613 - Surgical and medical procedures 10040668 Sigmoid hemicolectomy LLT
    14.0 10042613 - Surgical and medical procedures 10009879 Colectomy total PT
    14.0 10042613 - Surgical and medical procedures 10059848 Proctocolectomy PT
    14.0 10042613 - Surgical and medical procedures 10019460 Hemicolectomy LLT
    14.0 10042613 - Surgical and medical procedures 10039153 Right hemicolectomy LLT
    14.0 10042613 - Surgical and medical procedures 10024107 Left hemicolectomy LLT
    14.0 10042613 - Surgical and medical procedures 10063950 Ileocolectomy PT
    14.0 10042613 - Surgical and medical procedures 10042609 Surgery PT
    14.0 10042613 - Surgical and medical procedures 10061778 Colectomy PT
    14.0 10042613 - Surgical and medical procedures 10044083 Total colectomy LLT
    14.0 10042613 - Surgical and medical procedures 10009878 Colectomy partial LLT
    14.0 10042613 - Surgical and medical procedures 10009880 Colectomy transverse LLT
    14.0 10042613 - Surgical and medical procedures 10033684 Panproctocolectomy LLT
    14.0 10042613 - Surgical and medical procedures 10044447 Transverse colectomy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-000271-42 Sponsor Protocol Number: 11012007 Start Date*: 2007-05-08
    Sponsor Name:Matti Eskelinen
    Full Title: OKSIKODONIN ANALGEETTINEN PITOISUUS PLASMASSA YHDESSÄ PARASETAMOLIN 1g TAI 2g IV KANSSA ANNETTUNA MAHAKIRURGISILLA POTILAILLA
    Medical condition: Tutkimukseen otetaan 24 sappileikkaukseen tulevaa perustervettä aikuispotilasta.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10017641 Gallbladder disease LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-002542-38 Sponsor Protocol Number: CAEB071A2210 Start Date*: 2007-11-28
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A randomized, double blind, placebo controlled, parallel group design study to explore the efficacy, safety and tolerability of AEB071 in patients with active, moderate to severe ulcerative colitis.
    Medical condition: Ulcerative colitis
    Disease: Version SOC Term Classification Code Term Level
    14.0 10017947 - Gastrointestinal disorders 10045365 Ulcerative colitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended) DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-005254-68 Sponsor Protocol Number: GEL/TAMO-2006 Start Date*: 2007-04-13
    Sponsor Name:GEL/TAMO (Cooperative Spanish Group of Lymphoma/Autologous bone marrow transplant).
    Full Title: Treatment with R-MegaCHOP and early rescue with R-IFE and autologous stem cells transplant (ASCT) according response measured by positron emission tomography (PET) in patients with diffuse large B-...
    Medical condition: Diffuse Large B-Cell Lymphoma (DLBCL)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-005152-16 Sponsor Protocol Number: BV-2007/04 Start Date*: 2008-10-07
    Sponsor Name:OM Pharma SA
    Full Title: Multicentre, randomised, double-blind, placebo-controlled study of the efficacy and safety of Broncho-Vaxom in adults suffering from chronic rhinosinusitis
    Medical condition: Chronic rhinosinusitis
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10052106 Rhinosinusitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2007-005163-94 Sponsor Protocol Number: BAY81-8781/12946 Start Date*: 2010-10-08
    Sponsor Name:Bayer HealthCare AG
    Full Title: A prospective, randomized, verum controlled, open label, parallel group multi-center phase III clinical trial to demonstrate the superiority of 500 or 250 mg Aspirin® i.v. (BAY 81-8781) treatment v...
    Medical condition: Acute coronary syndrome (ACS)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10051592 Acute coronary syndrome PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-005164-27 Sponsor Protocol Number: 260981 Start Date*: 2008-02-22
    Sponsor Name:research office urology VUmc
    Full Title: Botulinum toxin A intravesical injections in the treatment of Bladder Pain Syndrome/ Interstitial Cystitis
    Medical condition: Interstitial Cystitis (IC) is a syndrome characterized by bladder pain associated with urgency, frequency, nocturia, dysuria and sterile urine. The patho-physiology remains largely unclear. No univ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-005169-36 Sponsor Protocol Number: NKV110721 Start Date*: 2008-02-07
    Sponsor Name:GlaxoSmithKline Research and Development Limited
    Full Title: NKV110721, A Study of Single Dose Intravenous Casopitant in Combination with Ondansetron and Dexamethasone for the Prevention of Oxaliplatin-Induced Nausea and Vomiting
    Medical condition: Prevention of nausea and vomiting due to first cycle of oxaliplatin based chemotherapy in patients with colorectal cancer receiving a combination with 5-fluorouracil and leucovorin, or in combinati...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) CZ (Completed) DE (Completed) HU (Completed) IT (Completed) SK (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2005-002494-75 Sponsor Protocol Number: CL3-12911-018 Start Date*: 2006-04-26
    Sponsor Name:Institut de Recherches Internationales Servier
    Full Title: The efficacy and safety of two doses of strontium ranelate (1g and 2g per day) versus placebo administered orally for 3 years in the treatment of knee osteoarthritis. A prospective multicentre, int...
    Medical condition: Osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    7.0 10031161 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed) BE (Completed) GB (Completed) ES (Completed) IT (Completed) DK (Completed) PT (Completed) LT (Completed) EE (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2007-000971-41 Sponsor Protocol Number: GGCP032/07 Start Date*: 2007-07-03
    Sponsor Name:Grupo Gallego de Cáncer de Pulmón
    Full Title: Estudio fase II de bevacizumab en combinación con vinorelbina y cisplatino, como tratamiento de primera línea de pacientes con cáncer de pulmón no microcítico,no epidermoide, estadio IIIB con derra...
    Medical condition: Cáncer de pulmón no microcítico(CPNM), no epidermoide, estadio IIIB con derrame pleural o IV / on-small cell, non-squamous lung cancer, stage IIIb with pleural effusion or stage IV.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10029522 Non-small cell lung cancer stage IV PT
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10029521 Non-small cell lung cancer stage IIIB PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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