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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44339   clinical trials with a EudraCT protocol, of which   7369   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,339 result(s) found. Displaying page 281 of 2,217.
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    EudraCT Number: 2004-000763-98 Sponsor Protocol Number: HP184B/2002 Start Date*: 2004-12-08
    Sponsor Name:Aventis Pharmaceuticals Inc.
    Full Title: A phase II, double-blind, placebo-controlled, multicenter study to assess the efficacy and safety of HP184 at 100, 200 and 400 mg doses administered orally once daily for twenty-four weeks in adult...
    Medical condition: Chronic spinal cord injury
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2004-000786-35 Sponsor Protocol Number: ITAL-04-002 Start Date*: 2004-11-02
    Sponsor Name:ABBOTT
    Full Title: A phase III, open-label, randomized, comparative study of the antiviral efficacy of ARV therapy with Lopinavir/Ritonavir (LPV/r - Kaletra) in combination with Tenofovir versus SOC (Kaletra in combi...
    Medical condition: Treatment of HIV infection in naive HIV-1 positive patients
    Disease: Version SOC Term Classification Code Term Level
    6.1 10020162 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2004-000795-14 Sponsor Protocol Number: 0089 Start Date*: 2004-07-26
    Sponsor Name:AstraZeneca
    Full Title: A Multicentre, Randomised, Double-blind, Placebo-controlled, Study on the Use of Prophylactic Meropenem Therapy in Subjects with Severe Acute Necrotizing Pancreatitis
    Medical condition: severe acute necrotisng pancreatitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LV (Completed) LT (Completed)
    Trial results: View results
    EudraCT Number: 2004-000804-41 Sponsor Protocol Number: CECOG/NSCLC.3.2.002 Start Date*: 2004-12-30
    Sponsor Name:CECOG
    Full Title: Phase II Trial of Dose-Dense Paclitaxel and Cisplatin as Neo-Adjuvant Chemotherapy for Operable Stage II and IIIA Non-Small Cell Lung Cancer
    Medical condition: Operable Stage II and IIIA Non-Small Cell Lung Cancer
    Disease: Version SOC Term Classification Code Term Level
    7.0 10061873 NSLC
    Population Age: Adults Gender: Male, Female
    Trial protocol: HU (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2004-000930-35 Sponsor Protocol Number: MHE100901 Start Date*: 2005-05-26
    Sponsor Name:GLAXO SMITHKLINE
    Full Title: An open-label extension study to study 100185, to evaluate long-term safety, efficacy and optimal dosing frequency of 750mg intravenous mepolizumab in subjects with hypereosinophilic syndrome.
    Medical condition: HES
    Disease: Version SOC Term Classification Code Term Level
    14.1 10005329 - Blood and lymphatic system disorders 10048643 Hypereosinophilic syndrome PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2004-000671-34 Sponsor Protocol Number: CVAA489A2305 Start Date*: 2005-01-14
    Sponsor Name:Novartis Pharma AG
    Full Title: A randomized, double-blind, multicenter, active-controlled, parallel design trial to evaluate the safety and efficacy of the combination of valsartan/amlodipine 160/5 mg or 160/10 mg versus valsart...
    Medical condition: hypertension
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Completed) LV (Completed) LT (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-000673-57 Sponsor Protocol Number: PRO-RENAL-REG-063 Start Date*: 2004-11-15
    Sponsor Name:Baxter Healthcare S.A.
    Full Title: Efficacy and Safety of Epoetin-Omega i.v. for Treatment of Anemia in Hemodialyzed Patients Hyporesponsive to a Previous Epoetin Beta i.v. Treatment: a Randomized, Parallel Group Trial.
    Medical condition: Anaemia in End Stage Renal Disease (ESRD) Hemodialyzed Patients Hyporesponsive to a Previous Epoetin Beta i.v. Treatment
    Disease: Version SOC Term Classification Code Term Level
    7.0 10009120 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2004-002818-11 Sponsor Protocol Number: 2003AN004 Start Date*: 2004-12-08
    Sponsor Name:Heart of England NHS Foundation Trust
    Full Title: Magnesium Sulphate for the Prevention of Super Ventricular Dysrrhythmias following Non-Cardiac Thoracic Surgery
    Medical condition: Post Thoracotomy Super Ventricular Dysrhythmias
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2004-002824-16 Sponsor Protocol Number: 03-624 Start Date*: 2004-12-21
    Sponsor Name:Karolinska Universitetssjukhuset
    Full Title: Spinalt klonidin och baklofen som adjuvans till ryggmärgsstimulering vid terapiresistent smärta. (Möjlighet att förstärka den smärtlindrande effekten av alektrisk tyggmärgsstimulering med läkemedel...
    Medical condition: Neuropathic pain patients with insufficient pain-relief of trial spinal cord stimulation.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-002070-36 Sponsor Protocol Number: GLU-005 Start Date*: 2004-12-22
    Sponsor Name:Metcon Medicin AB
    Full Title: Efficacy of MM005-Granulae as prophylaxis for nocturnal hypoglycemia in insulin treated Type 1 diabetic subjects. A double-blind, randomized, placebo-controlled phase II multi-center study in three...
    Medical condition: Diabetes type I
    Disease: Version SOC Term Classification Code Term Level
    6,1 10045228 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2004-002114-11 Sponsor Protocol Number: SER-LEV-2004-01 Start Date*: 2005-05-09
    Sponsor Name:Infociencia Clinical Research
    Full Title: A double blind, randomized, placebo-controlled, cross-over study to evaluate the effects of Levetiracetam on membrane excitability properties of afferent myelinated and unmyelinated fibers and chan...
    Medical condition: Neuropathic pain due to a traumatic nerve lesion
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-004401-26 Sponsor Protocol Number: CT-830-04-0004 Start Date*: 2005-03-21
    Sponsor Name:STADA R&D GmbH
    Full Title: Evaluation of the Safety of a Formulation Containing Epoetin (Epoetin STADA) Administered Intravenously for the Maintenance Treatment of Renal Anemia: an Open Follow-up Trial. Study code (CRO) 411-...
    Medical condition: Anemia caused by terminal renal insufficiency
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2004-004439-70 Sponsor Protocol Number: TOC100224 Start Date*: 2005-05-20
    Sponsor Name:GlaxSmithKline Research & Development
    Full Title: A Randomised, Observer-blind, Multicentre, Non-inferiority, Comparative Study of the Safety and Efficacy of Topical 1% SB-275833 Ointment, Applied Twice Daily for 5 Days, versus Topical 2% Sodium F...
    Medical condition: Impetigo
    Disease: Version SOC Term Classification Code Term Level
    7.1 10021531 PT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2004-004448-30 Sponsor Protocol Number: 1009/04 Start Date*: 2005-01-17
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: METRONOMIC THERAPY ,ORAL SOMMINISTRATION OF LOW DOSES OF CYCLOPHOSPHAMIDE AND DEXAMETHASONE IN PATIENTS WITH HORMONE-REFRACTORY PROSTATE CARCINOMA
    Medical condition: HORMONE-REFRACTORY PROSTATE CARCINOMA
    Disease: Version SOC Term Classification Code Term Level
    6.1 10029096 PT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-000073-64 Sponsor Protocol Number: 003 Start Date*: 2004-09-03
    Sponsor Name:Merck & Co., Inc./Suomen MSD Oy
    Full Title: A Randomized, Double-Blind, Placebo-Controlled, Parallel Groups Study to Assess the Effects of L-000124467 on Disease Activity in Patients with Relapsing-Remitting Multiple Sclerosis as Measured by...
    Medical condition: Aaltomainen MS-tauti
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2004-000089-11 Sponsor Protocol Number: AX-CL-09 Start Date*: 2004-12-15
    Sponsor Name:Axonyx Inc
    Full Title: A randomised, double-blind, placebo-controlled study to evaluate the safety and efficacy of two different doses of phenserine-tartrate in patients with probable mild to moderate Alzheimer’s disease
    Medical condition: Alzheimer's Disease is caused by a loss of nerve cells in the brain, particularly in the areas associated with memory and learning. The onset of Alzheimer's also affects the levels of a certain neu...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-001623-38 Sponsor Protocol Number: 060103 Start Date*: 2004-11-05
    Sponsor Name:Baxter AG
    Full Title: Phase 3B Recombinant Antihemophilic Factor Manufactured and Formulated without added Human or Animal Proteins (rAHF-PFM): Evaluation of Immunogenicity, Efficacy, and Safety in Previously Untreated ...
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    9.1 10060612 Hemophilia A LLT
    Population Age: Newborns, Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2004-005010-37 Sponsor Protocol Number: 62 Start Date*: 2005-08-16
    Sponsor Name:Suffolk Mental Health Partnerships Trust
    Full Title: Enhancing cognition in bipolar disorder
    Medical condition: Bipolar affective disorder, currently in remission
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-005016-93 Sponsor Protocol Number: Start Date*: 2005-04-01
    Sponsor Name:Vrinnevi Hospital
    Full Title: Oral immunoglobulin - a novel treatment of children with Crohn´s disease
    Medical condition: Children with the chronic inflammatory bowel Crohn´s disease in an active phase
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-005023-18 Sponsor Protocol Number: V232-054-00 Start Date*: 2005-06-09
    Sponsor Name:Merck Sharp & Dohme (Sweden) AB
    Full Title: Study in Healthy Young Adults to Assess the Safety, Tolerability, and Immunogenicity of a Recombinant Hepatitis B Vaccine Manufactured by a Process Upgrade
    Medical condition: Acute hepatitis B without delta-agent and without hepatic coma
    Disease: Version SOC Term Classification Code Term Level
    7.1 10019731 LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed) FI (Completed)
    Trial results: View results
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    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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