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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44336   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,336 result(s) found. Displaying page 487 of 2,217.
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    EudraCT Number: 2005-001487-32 Sponsor Protocol Number: 2538 Start Date*: 2005-12-14
    Sponsor Name:Linköping University
    Full Title: Evaluation of Corticosteroids on Idiopathic Sudden Sensorineural Hearing Loss
    Medical condition: Idiopatic Sudden Sensorineural Hearing Loss
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-001497-27 Sponsor Protocol Number: BY1023/M3-713 Start Date*: 2005-08-12
    Sponsor Name:ALTANA Pharma AG
    Full Title: Effect of pantoprazole on sleep-related breathing disorders
    Medical condition: Sleep-related breathing disorders
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-017503-29 Sponsor Protocol Number: CACZ885H2356E1 Start Date*: 2010-03-23
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A randomized, controlled extension study of CACZ885H2356 on the treatment and prevention of gout flares in patients with frequent flares for whom NSAIDs and/ or colchicine are contraindicated, not ...
    Medical condition: Treatment and prevention of gout flares in patients with frequent flares for whom NSAIDs and/ or colchicine are contraindicated, not tolerated or ineffective
    Disease: Version SOC Term Classification Code Term Level
    12.1 10018627 Gout LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LT (Completed) BE (Completed) LV (Completed) DE (Completed) EE (Completed) SE (Completed)
    Trial results: View results
    EudraCT Number: 2009-014681-25 Sponsor Protocol Number: DC 0982 GE 203 1B Start Date*: 2009-10-21
    Sponsor Name:PIERRE FABRE MEDICAMENT-IRPF-IDPF
    Full Title: Pharmacodynamic and clinical assessment of DC 982 GE (2,4 or 6 capsules per day) in patients with chronic venous disorders : randomised, placebo-controlled, dose effect, double blind, parallel gro...
    Medical condition: Treatment of venous lymphatic insufficiency symptoms related to chronic venous disorders.
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: FR (Completed) EE (Completed) LT (Completed)
    Trial results: View results
    EudraCT Number: 2009-014719-11 Sponsor Protocol Number: 2009/08 H1N1 Start Date*: 2009-09-18
    Sponsor Name:University of Oxford
    Full Title: Open Label, Randomized, Parallel-Group, Multi-Center Study to Evaluate the Safety, Tolerability and Immunogenicity of Baxter H1N1 vaccine and GlaxoSmithKline H1N1 vaccine in children 6 months to 12...
    Medical condition: Prophylaxis of influenza in an officially declared pandemic situation.
    Disease: Version SOC Term Classification Code Term Level
    12.0 10059429 Influenza immunisation LLT
    12.0 10059637 Influenza antibody test LLT
    12.0 10059642 Influenza antibody test positive LLT
    12.0 10059643 Influenza antibody test negative LLT
    12.0 10060063 Influenza serology LLT
    12.0 10060078 Influenza serology positive LLT
    12.0 10060079 Influenza serology negative LLT
    12.0 10022000 Influenza LLT
    12.0 10022002 Influenza A virus infection LLT
    12.0 10022001 Influenza (epidemic) LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-021266-30 Sponsor Protocol Number: A1481283 Start Date*: 2011-12-14
    Sponsor Name:Pfizer Inc., 235 East 42nd Street, New York, NY 10017
    Full Title: A FOLLOW UP INVESTIGATION FOR PATIENTS COMPLETING STUDY A1481276 TO INVESTIGATE DEVELOPMENTAL PROGRESS 12 AND 24 MONTHS FOLLOWING COMPLETION OF SILDENAFIL TREATMENT
    Medical condition: Persistent pulmonary hypertension of the newborn (PPHN)
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004850 10053592 Newborn persistent pulmonary hypertension LLT
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-021295-28 Sponsor Protocol Number: ottavi Start Date*: 2010-09-30
    Sponsor Name:AZIENDA OSPEDALIERA MAGGIORE DELLA CARITA` DI NOVARA
    Full Title: therapy antiedemigena through administration of corticosteroidi after surgical extraction of the teeth of the judgment.
    Medical condition: This study is going to be performed on patients afferent to the service of Chirurgia Maxillo Facciale dell’Ospedale Maggiore della Carita` di Novara subject to eights bony included extraction.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10042613 SOC
    Population Age: In utero, Preterm newborn infants, Newborns, Infants and toddlers, Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-015898-12 Sponsor Protocol Number: GLPG0259-CL-201 Start Date*: 2010-12-10
    Sponsor Name:Galápagos NV
    Full Title: Randomized, Double-Blind, Placebo-Controlled, Multicenter, Exploratory Phase II Study to Compare Three Dose Regimens of GLPG0259 vs Placebo, in Combination with Methotrexate, Administered for 12 We...
    Medical condition: Patients with active rheumatoid arthritis and an inadequate response to Methotrexate
    Disease: Version SOC Term Classification Code Term Level
    13.1 10028395 - Musculoskeletal and connective tissue disorders 10039073 Rheumatoid arthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2009-015902-20 Sponsor Protocol Number: GHB-CS07 Start Date*: 2009-11-04
    Sponsor Name:AVIR Green Hills Biotechnology Research Development Trade AG
    Full Title: Randomized, double-blind, placebo-controlled, Phase IIa dose finding study of single dose GHB11L1 in healthy adults
    Medical condition: GHB-CS07 is a healthy volunteer trial. The intended indication for the investigational medicinal product (GHB11L1) is prevention of influenza A (H1N1).
    Disease: Version SOC Term Classification Code Term Level
    12.0 10022002 Influenza A virus infection LLT
    Population Age: Adults Gender: Male
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-015927-94 Sponsor Protocol Number: PCOS NASH LIRAGLUTIDE Start Date*: 2010-02-08
    Sponsor Name:Hull and East Yorkshire NHS Trust
    Full Title: Are early and late cardiovascular risk markers in women with Polycystic Ovary Syndrome increased with concomitant Nonalcoholic Steatohepatitis and can this be modified with Liraglutide?
    Medical condition: Polycystic Ovary Syndrome Non-alcoholic Steatohepatitis
    Disease: Version SOC Term Classification Code Term Level
    12.0 10065161 Polycystic ovarian syndrome LLT
    12.0 10053219 Non-alcoholic steatohepatitis LLT
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-008529-32 Sponsor Protocol Number: OUPneumo-141108 Start Date*: 2009-01-08
    Sponsor Name:U.O.PNEUMOLOGIA- AZ. USL1 DI MASSA E CARRARA
    Full Title: Evaluation of erdosteine effect on systemic inflamation biomarkers during COPD exacerbations
    Medical condition: COPD exacerbation
    Disease: Version SOC Term Classification Code Term Level
    9.1 10038738 SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-016300-23 Sponsor Protocol Number: RAA 2009-007 Start Date*: 2009-12-14
    Sponsor Name:King's College London
    Full Title: Pilot double blind randomised placebo controlled crossover trial of Hyoscine for the treatment of Clozapine induced nocturnal sialorrhoea.
    Medical condition: Sialorrhoea in patients treated with clozapine.
    Disease: Version SOC Term Classification Code Term Level
    12.0 10059812 Sialorrhoea LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-016317-20 Sponsor Protocol Number: SCA_LITIO_12 Start Date*: 2009-10-26
    Sponsor Name:UNIVERSITA` DEGLI STUDI DI NAPOLI FEDERICO II
    Full Title: PILOT STUDY TO ASSESS SAFETY AND TOLERABILITY OF LITHIUM ON SPINOCEREBELLAR ATAXIA OF TYPE 2
    Medical condition: Spinocerebellar ataxia type 2
    Disease: Version SOC Term Classification Code Term Level
    9.1 10031722 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-017356-28 Sponsor Protocol Number: PAW004 Start Date*: 2010-04-21
    Sponsor Name:University of Dundee
    Full Title: Evaluation of Beta Blockers for the Treatment of Asthma. A randomised controlled trial of propranolol.
    Medical condition: asthma
    Disease: Version SOC Term Classification Code Term Level
    12.1 10003553 Asthma LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-002845-36 Sponsor Protocol Number: PK200609 Start Date*: 2006-11-14
    Sponsor Name:Newcastle upon Tyne Hospitals NHS Foundation Trust
    Full Title: Pharmacokinetics and pharmacogenetics of anticancer drugs in infants and young children
    Medical condition: Any childhood cancer.
    Disease:
    Population Age: Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-002847-96 Sponsor Protocol Number: DRI6012 Start Date*: Information not available in EudraCT
    Sponsor Name:Sanofi aventis US Inc.
    Full Title: A 13-week Multinational, Randomized, Double-Blind, Placebo-Controlled, Dose-Response Trial Assessing the Safety, Tolerability and Efficacy of AVE0010 in Metformin-Treated Subjects with Type 2 Diabe...
    Medical condition: The current study is designed to confirm the already observed clinically meaningful pharmacodynamic effect of AVE0010 on glycemic control, as measured by HbA1c, and to determine the clinically rele...
    Disease: Version SOC Term Classification Code Term Level
    8.1 10012613 Diabetes mellitus non-insulin-dependent LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BG (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-020399-41 Sponsor Protocol Number: CZOL446H2337E1 Start Date*: 2013-03-25
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A 1-year, multicenter, open-label extension to CZOL446H2337 to evaluate safety and efficacy of zoledronic acid twice yearly in osteoporotic children treated with glucocorticoids
    Medical condition: Treatment of osteoporosis in a paediatric population (aged 5 to 19 years old) treated with systemic glucocorticoids (i.v. or oral)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10031282 Osteoporosis PT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2010-020401-32 Sponsor Protocol Number: darbepoetina Start Date*: 2010-01-25
    Sponsor Name:AZIENDA OSPEDALIERA OSPEDALE POLICLINICO CONSORZIALE
    Full Title: IDENTIFICATION OF OXIDATIVE-STRESS AND MICROINFLAMMATION GENES MODULATED BY ERYTHROPOIETIN ADMINISTRATION IN PATIENTS WITH RENAL TRANSPLANT AND CHRONIC RENAL FAILURE. PERSPECTIVES FOR ERYTHROPOITIN...
    Medical condition: PATIENTS WITH RENAL TRANSPLANT AND CHRONIC RENAL FAILURE
    Disease: Version SOC Term Classification Code Term Level
    9.1 10038359 SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-020220-22 Sponsor Protocol Number: H6D-MC-LVIR Start Date*: 2010-12-21
    Sponsor Name:Eli Lilly and Company
    Full Title: A Randomized, Double-Blind, Placebo Controlled Study to Evaluate the Effect of Tadalafil Once Daily for 8 Weeks on Prostatic Blood Flow and Perfusion Parameters in Men with Signs and Symptoms of Be...
    Medical condition: Benign Prostatic Hyperplasia (BPH)
    Disease: Version SOC Term Classification Code Term Level
    14.0 10038604 - Reproductive system and breast disorders 10004446 Benign prostatic hyperplasia PT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: BE (Completed) AT (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2009-017782-30 Sponsor Protocol Number: Lucentis in CRVO Start Date*: 2010-03-22
    Sponsor Name:Medizinische Universität Graz, Universitäts-Augenklinik
    Full Title: Treatment of macular edema due to central retinal vein occlusion with ranibizumab (Lucentis®).
    Medical condition: This case-series is designed to evaluate the safety and efficacy of intravitreal ranibizumab (Lucentis®) in the treatment of macular edema due to central retinal vein occlusion.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10007972 Central retinal vein occlusion LLT
    12.1 10054467 Macular edema LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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