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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44341   clinical trials with a EudraCT protocol, of which   7370   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,341 result(s) found. Displaying page 70 of 2,218.
    EudraCT Number: 2008-001122-13 Sponsor Protocol Number: BP21850 Start Date*: 2009-05-08
    Sponsor Name:F. Hoffmann-La Roche Ltd
    Full Title: Multi-center, randomized, double-blind, 5-arm parallel group, placebo controlled 4 week study to investigate the safety, tolerability and efficacy of two doses each (near to maximum tolerated dose ...
    Medical condition: Type 2 Diabetes (T2D)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10012613 Diabetes mellitus non-insulin-dependent LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2008-001125-34 Sponsor Protocol Number: 012008S Start Date*: 2008-05-08
    Sponsor Name:Arvi Yli-Hankala
    Full Title: Leikkauksen jälkeisen kivun voimakkuus propofoli- tai sevofluraanianestesian jälkeen.
    Medical condition: Potilaat tulevat tähystyksessä tehtävään kohdunpoistoleikkaukseen.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10021151 Hysterectomy LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-001128-30 Sponsor Protocol Number: BIIT001 Start Date*: 2008-05-07
    Sponsor Name:SE Dept. of Psychiatry and Psychotherapy
    Full Title: EFFICACY OF SERTINDOLE AS COMPARED TO OLANZAPINE OR RISPERIDONE ON PREATTENTIONAL AND ATTENTION-DEPENDENT FUNCTIONS IN PATIENTS WITH CHRONIC SCHIZOPHRENIA. A COGNITIVE AND FMRI STUDY.
    Medical condition: schizophrenia
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-001158-42 Sponsor Protocol Number: 014-012/08 Start Date*: 2008-05-21
    Sponsor Name:Dermatologikum Hamburg
    Full Title: Proof-of-concept study: Prüfung der Wirksamkeit und der Verträglichkeit von Botulinum-Toxin (Xeomin®) bei der Behandlung von Krähenfüßen im Vergleich zu Vistabel® im intraindividuellen Vergleich
    Medical condition: Moderate to severe crow`s feet
    Disease: Version SOC Term Classification Code Term Level
    9.1 10052611 Crow's feet LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-005619-16 Sponsor Protocol Number: Start Date*: 2009-10-07
    Sponsor Name:Erasmus Medical Center
    Full Title: Impact of anti-tumor necrosis factors antibodies treatment on fertility of inflammatory bowel diseases male patients
    Medical condition: Fertility influenced by antiTNF treatment
    Disease: Version SOC Term Classification Code Term Level
    9.1 10016469 Fertility investigations LLT
    Population Age: Adults Gender: Male
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-005638-56 Sponsor Protocol Number: 0805603 Start Date*: 2009-02-16
    Sponsor Name:CHU de TOULOUSE
    Full Title: Protocole IFM 2008 : Primo-traitement des patients de moins de 65 ans atteints de myélome
    Medical condition: Myelome, Myelome multiple
    Disease: Version SOC Term Classification Code Term Level
    9.1 10028566 Myeloma LLT
    9.1 10028228 Multiple myeloma LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-012983-14 Sponsor Protocol Number: DMS32212R Start Date*: 2009-10-21
    Sponsor Name:BioNumerik Pharmaceuticals, Inc.
    Full Title: Randomized, multicenter, double-blind, phase 3 trial of Tavocept versus Placebo in patients with newly diagnosed or relapsed advanced (stage IIIB/IV) primary adenocarcinoma of the lung treated with...
    Medical condition: Newly diagnosed or relapsed advanced (Stage IIIB/IV) primary adenocarcinoma of the lung
    Disease: Version SOC Term Classification Code Term Level
    9.1 10025031 Lung adenocarcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Prematurely Ended) BG (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-014448-13 Sponsor Protocol Number: 113572 Start Date*: 2009-09-02
    Sponsor Name:GlaxoSmithKline Biologicals
    Full Title: A phase III, randomised, single-blind study to evaluate the immunogenicity and safety of sequential administration of a licensed seasonal trivalent vaccine and the pandemic H1N1 influenza candidate...
    Medical condition: Immunization against A/California/7/2009 (H1N1)v-like influenza in male and female subjects aged 61 years or above.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-012499-28 Sponsor Protocol Number: HLS01/2009 Start Date*: 2009-08-07
    Sponsor Name:AZIENDA OSPEDALIERA L. SACCO (A.O. DI RILIEVO NAZIONALE)
    Full Title: Efficacy of the treatment with hydroxychloroquine in non responders HIV-infected HAART-treated patients
    Medical condition: HIV infection (immunological nonresponders).
    Disease: Version SOC Term Classification Code Term Level
    9.1 10008922 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-014313-27 Sponsor Protocol Number: RAL-IC Start Date*: 2009-11-11
    Sponsor Name:Fundació Lluita contra la SIDA
    Full Title: ESTUDIO PILOTO PARA COMPARAR LOS PARÁMETROS FARMACOCINÉTICOS EN PLASMA E INTRACELULARES DE RALTEGRAVIR ADMINISTRADO UNA VEZ AL DÍA EN PACIENTES ADULTOS INFECTADOS POR EL VIH.
    Medical condition: Infección VIH-1
    Disease: Version SOC Term Classification Code Term Level
    9 10008919 Chronic HIV infection LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2008-005325-10 Sponsor Protocol Number: DC2008exe001 Start Date*: 2009-04-08
    Sponsor Name:VU University Medical Center
    Full Title: The effect of exenatide compared to insulin glargine on cardiac function and metabolism in type 2 diabetic patients with congestive heart failure (NYHA II): a randomized-controlled trial
    Medical condition: Cardiac function and metabolism in type 2 diabetic patients with congestive heart failure
    Disease: Version SOC Term Classification Code Term Level
    9.1 10045242 Type II diabetes mellitus LLT
    9.1 10010684 Congestive heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-001367-11 Sponsor Protocol Number: CIBERehd-ALICANTE-02/08 Start Date*: 2008-07-31
    Sponsor Name:UNIDAD HEPATICA. CIBERehd. HOSPITAL GENERAL UNIVERSITARIO DE ALICANTE
    Full Title: Estudio piloto, en fase IV para evaluar la influencia de la asociación de descontaminación intestinal selectiva (DIS) con norfloxacino a antibioterapia estándar sobre la traslocación bacteriana y ...
    Medical condition: PERITONITIS BACETERIANA ESPONTÁNEA (SPONTANEOUS BACTERIAL PERITONITIS)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10061135 Spontaneous bacterial peritonitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-002565-39 Sponsor Protocol Number: 2006015 Start Date*: 2006-11-27
    Sponsor Name:South Tees Acute Hospitals NHS Trust
    Full Title: Effects of the Modification of the Daily Flow Rate with a Constant Daily Dose on Patient's Reported Analgesia in Intathecal Therapy
    Medical condition: Chronic Pain.
    Disease: Version SOC Term Classification Code Term Level
    8.1 10049475 Chronic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-015589-74 Sponsor Protocol Number: NYC-IBU-1 Start Date*: 2009-10-02
    Sponsor Name:Nycomed Sweden Holding 2 AB
    Full Title: A controlled, randomized, double-blind, cross-over study of the onset of analgesic effect of two formulations of ibuprofen for the treatment of pain after oral surgery.
    Medical condition: Pain
    Disease: Version SOC Term Classification Code Term Level
    12.0 10033371 Pain LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2006-006436-22 Sponsor Protocol Number: BAY a 1040 - BAY 68-9291/12313 Start Date*: 2007-08-29
    Sponsor Name:BAYER
    Full Title: A multicenter Study Evaluating the Efficacy of Nifedipine GITS ヨ Telmisartan Combination in Blood Pressure Control and Beyond: comparison of two strategies.
    Medical condition: Hypertension
    Disease: Version SOC Term Classification Code Term Level
    6.1 10020772 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2006-006439-39 Sponsor Protocol Number: Packat ver 5 Start Date*: 2007-04-25
    Sponsor Name:Lund University Hospital
    Full Title: Bisfosfonatbehandling av bentransplantat vid höftrevisionhöftplastikrevision utvärderat med radiostereofotogrametri. En randomiserad, dubbel-blind studie hos patienter opererade för osteolys och as...
    Medical condition: Revision of hip prostheses with osteolysis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-006441-14 Sponsor Protocol Number: CRIT124DDE04 Start Date*: 2007-04-18
    Sponsor Name:Novartis Pharma GmbH
    Full Title: A randomized, rater-blinded cross-over multicenter study comparing the clinical efficacy of Ritalin® LA (methylphenidate) treatment (20 or 40 mg orally o.d.) in children with ADHD under different b...
    Medical condition: attention deficit hyperactivity disorder (ADHD)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10064104 ADHD LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-002628-27 Sponsor Protocol Number: CAIN457A2206 Start Date*: 2009-01-15
    Sponsor Name:Novartis Pharma Services AG
    Full Title: Randomized, double-blind, placebo-controlled, multi-center, proof-of-concept study to assess the efficacy of AIN457 in patients with psoriatic arthritis
    Medical condition: Psoriatic arthritis (PsA), which belongs to seronegative spondyloarthropathies (SpA).
    Disease: Version SOC Term Classification Code Term Level
    9.1 10037160 Psoriatic arthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended) DE (Prematurely Ended) NL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-002655-24 Sponsor Protocol Number: SMR-1850/2PX-SP-02 Start Date*: 2008-09-30
    Sponsor Name:SantoSolve A/S
    Full Title: A randomised, double-blind, placebo (vehicle) controlled, parallel group study of the efficacy, safety and tolerability of topical 2PX (strontium chloride hexahydrate) in patients with chronic, mod...
    Medical condition: Post amputation patients (at least 6 months prior to visit 1) with chronic moderate-to-severe lower limb stump pain, defined as average stump pain on a daily basis (≥40 on a 100 mm pain VAS scale) ...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10023931 Late amputation stump complication LLT
    Population Age: Gender: Male, Female
    Trial protocol: DK (Completed) GB (Prematurely Ended) DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-007580-24 Sponsor Protocol Number: EB70 Start Date*: 2008-02-08
    Sponsor Name:Emotional Brain
    Full Title: A double blind, randomized, 3-arm placebo controlled study to investigate the subjective and physiological efficacy and safety of Lybrido and Lybridos in the domestic setting in healthy female subj...
    Medical condition: Hypoactive sexual desire disorder and female sexual arousal disorder
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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