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Clinical trials for Aging

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    107 result(s) found for: Aging. Displaying page 1 of 6.
    1  2  3  4  5  6  Next»
    EudraCT Number: 2005-001315-22 Sponsor Protocol Number: GH003 Start Date*: 2006-03-09
    Sponsor Name:Ludwig Boltzmann Gesellschaft
    Full Title: The effect of the cholinesterase inhibitor donepezil on organic and functional deficits related to growth hormone deficiency in old age.
    Medical condition: We plan to study healthy aging subjects.
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-003299-15 Sponsor Protocol Number: METFORAGING Start Date*: 2021-10-19
    Sponsor Name:Fundación para la Investigación Biomédica del Hospital La Paz
    Full Title: A double blinded, phase II, placebo controlled, single center randomized clinical trial to evaluate metformin compared with placebo for reversal of accelerated biological aging in persons living wi...
    Medical condition: Patients with HIV and accelerated biological aging
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-000870-51 Sponsor Protocol Number: CMCS240281 Start Date*: 2013-02-25
    Sponsor Name:Unidad de Gestión Clínica de Endocrinología y Nutrición
    Full Title: RANDOMIZED CLINICAL TRIAL TO ASSESS THE EFFICACY OF TESTOSTERONE UNDECANOATE, METFORMIN, OR THE COMBINATION OF BOTH, FOR THE TREATMENT OF ISOLATED HYPOGONADOTROPIC HYPOGONADISM AND ERECTILE DYSFUNC...
    Medical condition: Isolated hypogonadotropic hypogonadism related to obesity
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-000434-21 Sponsor Protocol Number: LP1 Start Date*: 2005-06-15
    Sponsor Name:Kognitive Neurologie, Institut für Medizin, Forschungszentrum Jülich
    Full Title: Neurochemische Modulation von Exekutiv- und Gedächtnisfunktionen
    Medical condition: Progressive cognitive decline in physiological aging
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-002425-21 Sponsor Protocol Number: 11054 Start Date*: 2012-02-10
    Sponsor Name:University of Nottingham
    Full Title: Efficacy of Dehydroepiandrosterone to overcome the effect of ovarian aging
    Medical condition: Women having low ovarian reserve undergoing IVF/ICSI treatment
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-002147-10 Sponsor Protocol Number: FLU-MARK Start Date*: 2011-09-21
    Sponsor Name:Institute for Biomedical Aging Research
    Full Title: Influenza vaccination in old age: Immunological and biogerontological characterization of responders and non-responders
    Medical condition: This study will analyze cellular and humoral immune responses after seasonal vaccination against influenza. Healthy adults are vaccinated with a licensed trivalent inactivated vaccine without adjuv...
    Disease: Version SOC Term Classification Code Term Level
    14.0 10042613 - Surgical and medical procedures 10016794 Flu vaccination LLT
    14.0 10042613 - Surgical and medical procedures 10046859 Vaccination LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2015-000284-14 Sponsor Protocol Number: Start Date*: 2016-01-05
    Sponsor Name:University of Calgary
    Full Title: Assessment of Metoprolol in the Prevention of Vasovagal Syncope in Aging Subjects
    Medical condition: Vasovagal Syncope
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2015-002682-30 Sponsor Protocol Number: RALATOR Start Date*: 2015-09-30
    Sponsor Name:Fundació Lluita contra la SIDA
    Full Title: Raltegravir-based regimen versus raltegravir-based regimen plus atorvastatin for reducing ?inflamaging? (aging-related complication) in HIV-infected patients older than 60 years.
    Medical condition: aging-related inflamation in HIV-infected patients
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004862 10020175 HIV infection with other conditions LLT
    18.0 100000004862 10008919 Chronic HIV infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2004-001545-15 Sponsor Protocol Number: 307720 Start Date*: 2004-11-04
    Sponsor Name:Schering AG
    Full Title: Estudio multicéntrico, doble ciego, aleatorizado, controlado con placebo de Testogel® (testosterona 50–100mg) para evaluar su eficacia y seguridad en hombres que presentan síntomas típicos de defic...
    Medical condition: Déficit Androgénico parcial en la edad avanzada.
    Disease:
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: ES (Completed) IE (Completed)
    Trial results: View results
    EudraCT Number: 2016-002894-36 Sponsor Protocol Number: IXIARO-booster-senescence Start Date*: 2017-12-22
    Sponsor Name:Medical University of Vienna (MUW)
    Full Title: "An open, monocentric, uncontrolled phase 4 trial to characterise cellular and humoral immune responses following the first booster immunisation with the inactivated, purified Japanese Encephalitis...
    Medical condition: The condition under investigation is the naturally aging immune system. The aim of this study is to investigate the immune responses following a booster immunisation with the Japanese Encephalitis ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-000891-54 Sponsor Protocol Number: REBOOT-II Start Date*: 2016-11-28
    Sponsor Name:Aging Research Center, Karolinska Institutet and Stockholm University
    Full Title: Effects of enhanced dopaminergic neurotransmission on working memory training efficiency in the healthy elderly - A prospective, single center, randomized, double blind, placebo controlled, paralle...
    Medical condition: No medical condition is under investigation. The project investigates normal age-related decline in intellectual abilities.
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-000650-21 Sponsor Protocol Number: PHARMADIPOAGE Start Date*: 2018-10-31
    Sponsor Name:Universidad Autónoma de Madrid
    Full Title: CLINICAL TRIAL FOR EVALUATION OF THE ADIPOQUINAS: NEW PHARMACOLOGICAL TARGETS TO PREVENT VASCULAR AGING
    Medical condition: PREDIABETES
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004861 10065542 Prediabetes LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-020357-14 Sponsor Protocol Number: CCFM154/310 Start Date*: 2011-05-16
    Sponsor Name:FONDAZIONE MONZINO CENTRO CARDIOLOGICO
    Full Title: EFFECTS OF BETA 2 RECEPTOR BLOCKADE ON PULMONARY FUNCTION IN A HUMAN MODEL OF ACUTE HYDRIC OVERLOAD
    Medical condition: BETA BLOCKADE AND LUNG FUNCTION
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-002788-25 Sponsor Protocol Number: Mirtazapine Combi Start Date*: 2005-08-18
    Sponsor Name:Department of Psychiatry and Psychotherapy, University of Erlangen-Nuremberg
    Full Title: Hippocampal volume in young adults with moderate to severe depression before and after combined antidepressant therapy
    Medical condition: moderate to severe depression (episodes and recurrent diseases)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-002060-17 Sponsor Protocol Number: 2015/077/HP Start Date*: 2015-08-21
    Sponsor Name:CHU - Hôpitaux de Rouen
    Full Title: Effect of pharmacological heart rate reduction on visco-elastic properties of the arterial wall - Impact of aging
    Medical condition: Healthy subjects between 25 and 65 years old
    Disease: Version SOC Term Classification Code Term Level
    18.0 10022891 - Investigations 10007574 Cardiac imaging procedures HLT
    18.0 10022891 - Investigations 10052677 Vascular imaging PT
    18.0 10007541 - Cardiac disorders 10006093 Bradycardia PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-002053-20 Sponsor Protocol Number: DC00065/91579 Start Date*: 2008-09-15
    Sponsor Name:Bayer Healthcare AG
    Full Title: A 54 week treatment, randomized, multi center, double blind, placebo controlled study to assess the safety and efficacy of NEBIDO 1000 mg (4 ml) in elderly men with symptomatic late onset hypogonad...
    Medical condition: Symptomatic late onset hypogonadism
    Disease: Version SOC Term Classification Code Term Level
    9.1 10021011 Hypogonadism male LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: LV (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-000266-11 Sponsor Protocol Number: 2012-772 Start Date*: 2014-05-27
    Sponsor Name:HOSPICES CIVILS DE LYON
    Full Title: Multicenter, randomized trial of carboplatin +/- paclitaxel in vulnerable elderly patients with stage III-IV advanced ovarian cancer.
    Medical condition: Vulnerable elderly women with newly diagnosed stage III-IV ovarian cancer after an initial debulking surgery or with a planned interval debulking surgery.
    Disease:
    Population Age: Elderly Gender: Female
    Trial protocol: IT (Completed) IE (Completed) DK (Prematurely Ended) FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-004170-25 Sponsor Protocol Number: MH-110 Start Date*: Information not available in EudraCT
    Sponsor Name:Bracco Imaging S.p.A.
    Full Title: A PHASE III, MULTI-CENTER, OPEN-LABEL STUDY TO EVALUATE SAFETY AND EFFICACY OF MULTIHANCE® AT THE DOSE OF 0.10 mmol/kg IN MAGNETIC RESONANCE IMAGING OF THE CENTRAL NERVOUS SYSTEM IN PEDIATRIC PA...
    Medical condition: imaging diagnosis of highly suspected or known brain and/or spine disease, which are known to impair the Blood Brain Barrier Function
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DE (Completed) BE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2011-001995-20 Sponsor Protocol Number: 2205p Start Date*: 2011-03-14
    Sponsor Name:AZIENDA OSPEDALIERA DI PADOVA
    Full Title: A pilot study on educational aproach to improve compliance to medical precriptions in transplantation recipients.
    Medical condition: Patients who underwent liver or renal transplantation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2014-003841-86 Sponsor Protocol Number: Y-52-52120-214 Start Date*: 2015-04-30
    Sponsor Name:Ipsen Innovation
    Full Title: A phase III, randomised, double blind, placebo controlled and open label phase, multicentre study to investigate the efficacy and safety of BTX-A-HAC NG in the treatment of moderate to severe glabe...
    Medical condition: Moderate to severe Glabellar lines
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004858 10052609 Glabellar frown lines LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) GB (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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