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Clinical trials for Anti-inflammatory

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    567 result(s) found for: Anti-inflammatory. Displaying page 1 of 29.
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    EudraCT Number: 2004-000283-27 Sponsor Protocol Number: VX04-765-201 Start Date*: 2004-07-19
    Sponsor Name:Vertex Pharmaceuticals Incorporated
    Full Title: A Pilot Open-Label Study to Investigate the Safety and Anti-inflammatory Effects of VX-765, an Orally Administered Interleukin-1β Converting Enzyme Inhibitor, in Patients with Muckle-Wells Syndrome
    Medical condition: Muckle-Wells syndrome
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2014-000361-52 Sponsor Protocol Number: prucalopride/VNS1 Start Date*: 2014-05-15
    Sponsor Name:KULeuven
    Full Title: Pilot study: Anti-inflammatory effect of preoperative stimulation of the enteric nervous system: a potential new therapeutic intervention to shorten gastroparesis
    Medical condition: Patients undergoing pancreaduodenectomy due to benign or malignant tumor drug will be studied for prokinetic or anti-inflammatory effects, because they are known to influence gastrointestinal mo...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-003296-30 Sponsor Protocol Number: 00172 Start Date*: 2015-11-11
    Sponsor Name:Raimo Tuuminen
    Full Title: Efficacy of steroid and nonsteroidal anti-inflammatory eye drops in management of post-operative inflammation and prevention of pseudophakic cystic macular edema after uncomplicated cataract surgery
    Medical condition: Cataract senilis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-005313-79 Sponsor Protocol Number: 00175 Start Date*: 2017-01-05
    Sponsor Name:Raimo Tuuminen
    Full Title: Non-steroidal anti-inflammatory medication in cataract surgery
    Medical condition: Cataract senilis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-005084-29 Sponsor Protocol Number: 1 Start Date*: 2006-03-23
    Sponsor Name:Chief Scientitst Office
    Full Title: The effect of intensive lipid lowering on markers of inflammation in patients with stable coronary artery disease.
    Medical condition: Patients with cardiovascular risk factors and stable coronary artery disease, with a fasting total cholesterol level ≥5 mmol/l.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2005-001466-14 Sponsor Protocol Number: MEN002 Start Date*: 2005-05-26
    Sponsor Name:University of Dundee
    Full Title: A Proof of Concept Study to Investigate the use of Simvastatin as a Putative Anti-inflammatory Agent in Asthma
    Medical condition: Asthma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-003041-14 Sponsor Protocol Number: 565 Start Date*: 2005-09-20
    Sponsor Name:Department of Clinical Pharmacology, Medical University of Vienna
    Full Title: Anti-inflammatory effect of statins in the human endotoxin model
    Medical condition: Healthy volunteers are tested in an endotoxemia model
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2016-004514-10 Sponsor Protocol Number: 00173 Start Date*: 2017-03-08
    Sponsor Name:Raimo Tuuminen
    Full Title: Pre and post-operative corticosteroid and NSAID combination treatment in cataract surgery of diabetic patient
    Medical condition: Cataract senilis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-004784-40 Sponsor Protocol Number: 00176 Start Date*: 2017-03-03
    Sponsor Name:Raimo Tuuminen
    Full Title: Anti-inflammatory medication in cataract surgery of pseudoexfoliation eyes
    Medical condition: Cataract senilis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-002173-22 Sponsor Protocol Number: 201800406 Start Date*: 2018-12-04
    Sponsor Name:University Medical Center Groningen
    Full Title: Anti-inflammatory effects of tiotropium in patients with stable COPD
    Medical condition: Chronic obstructive pulmonary disease (COPD)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-005534-19 Sponsor Protocol Number: FRIA_FATSURG_1 Start Date*: 2012-01-31
    Sponsor Name:Vrije Universiteit Brussel
    Full Title: The effect of peri-operative anti-inflammatory treatment on postoperative muscle weakness and muscle fatigue in elderly elective surgery patients: a double blinded randomized placebo-controlled trial.
    Medical condition: Post-operative muscle weakness, fatigue and inflammation.
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-003187-31 Sponsor Protocol Number: GN09CA403 Start Date*: 2015-03-19
    Sponsor Name:NHS Greater Glasgow & Clyde
    Full Title: Misoprostol for the Healing of Small Bowel Ulceration in Patients with Obscure Blood Loss while Taking Low-Dose Aspirin or Non-Steroidal Anti-inflammatory Drugs [MASTERS Trial]
    Medical condition: Small bowel ulcers associated with iron deficiency anaemia or obscure blood loss in patients using aspirin or non-steroidal anti-inflammatory drugs
    Disease: Version SOC Term Classification Code Term Level
    20.0 10005329 - Blood and lymphatic system disorders 10066761 Acute anaemia LLT
    20.0 10005329 - Blood and lymphatic system disorders 10057220 Acute post haemorrhagic anaemia LLT
    20.0 10005329 - Blood and lymphatic system disorders 10002034 Anaemia PT
    20.0 10005329 - Blood and lymphatic system disorders 10002034 Anaemia PT
    20.1 10005329 - Blood and lymphatic system disorders 10002083 Anaemia- Hypochromic microcytic picture LLT
    20.0 10005329 - Blood and lymphatic system disorders 10002062 Anaemia iron deficiency LLT
    20.0 10022891 - Investigations 10014816 Endoscopy small intestine PT
    20.0 10022891 - Investigations 10014816 Endoscopy small intestine PT
    20.1 10022891 - Investigations 10014817 Endoscopy small intestine abnormal PT
    20.1 10022891 - Investigations 10014818 Endoscopy small intestine normal PT
    20.1 10017947 - Gastrointestinal disorders 10041133 Small intestine ulcer PT
    20.1 10017947 - Gastrointestinal disorders 10041133 Small intestine ulcer PT
    20.1 10017947 - Gastrointestinal disorders 10041134 Small intestine ulcer haemorrhagic LLT
    20.1 10017947 - Gastrointestinal disorders 10055339 Small intestine ulcer hemorrhagic LLT
    20.0 10017947 - Gastrointestinal disorders 10045335 Ulcer small intestine LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2019-001762-14 Sponsor Protocol Number: 69765 Start Date*: 2020-07-29
    Sponsor Name:University Medical Center Groningen
    Full Title: Evaluation of the anti-inflammatory effects of glycopyrronium added to indacaterol/mometasone on the allergen-induced late asthmatic response
    Medical condition: Asthma
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-000164-42 Sponsor Protocol Number: 2016RC01 Start Date*: 2016-08-17
    Sponsor Name:Tayside Medical Sciences Centre on behalf of University of Dundee
    Full Title: JAB02 Repurposing allopurinol as a novel anti-inflammatory treatment for persistent allergic asthma.
    Medical condition: Asthma
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004855 10001705 Allergic asthma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2004-002769-18 Sponsor Protocol Number: MKC101614 Start Date*: 2005-05-03
    Sponsor Name:GlaxoSmithKline R&D
    Full Title: A 28-day, randomised, double-blind, placebo-controlled study to assess the safety, tolerability, anti-inflammatory effect and steadystate pharmacokinetics of SB-681323 7.5 mg per day in patients wi...
    Medical condition: Chronic Obstructive Pulmonary Disease (COPD)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) GB (Completed) DK (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-014408-71 Sponsor Protocol Number: 07/H0406/157 Start Date*: 2009-10-08
    Sponsor Name:UHL NHS Trust
    Full Title: Biomarkers to target antibiotic and systemic corticosteroid therapy in COPD exacerbations
    Medical condition: Exacerbations of chronic obstructive pulmonary disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-005622-31 Sponsor Protocol Number: MEN008 Start Date*: 2006-03-10
    Sponsor Name:University of Dundee
    Full Title: A Proof Of Concept Study To Investigate The Potential Role Of Acetylsalicyclic Acid (Aspirin) As An Anti-Inflammatory Agent For The Treatment Of Asthma
    Medical condition: Asthma
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-005287-24 Sponsor Protocol Number: BAR104 Start Date*: 2005-06-28
    Sponsor Name:Univ.-Kl. f.Augenheilkunde und Optometrie Wien
    Full Title: Effect of diclofenac-sodium, unpreserved diclofenac-sodium or ketorolac on the inflammatory response after cataract surgery
    Medical condition: intraocular inflammatory reaction after cataract-surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2004-005194-27 Sponsor Protocol Number: 240672 Start Date*: 2005-03-09
    Sponsor Name:Department of Neurology, Medical University of Vienna
    Full Title: Anti-inflammatory and/or antinociceptive effects of botulinum toxin A in an experimental inflammatory human skin pain model: a randomised, double blinded, placebo controlled study
    Medical condition: not applicable In this trial a potential antinociceptive potency af the IMP (Dysport) will be testet i9n a human inflammatory pain model. The present study will only include heathy volunteers.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: View results
    EudraCT Number: 2016-003802-14 Sponsor Protocol Number: CRC-PSO-SKINPEN-A-27 Start Date*: 2016-11-25
    Sponsor Name:Charité - Universitätsmedizin Berlin
    Full Title: Skin penetration of anti-inflammatory compounds in lesional compared to non-lesional skin of psoriasis patients
    Medical condition: Psoriasis vulgaris
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004858 10050576 Psoriasis vulgaris LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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