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Clinical trials for Aspirin

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   43873   clinical trials with a EudraCT protocol, of which   7293   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    390 result(s) found for: Aspirin. Displaying page 1 of 20.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2018-004285-34 Sponsor Protocol Number: STH20370 Start Date*: 2019-01-18
    Sponsor Name:Sheffield Teaching Hospitals NHS Foundation Trust
    Full Title: The impact of aspirin dose modification on the innate immune response - WILL lOWer dose aspirin Therapy ReducE the response to Endotoxin? – (WILLOW TREE)
    Medical condition: Acute coronary syndrome
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10051592 Acute coronary syndrome PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2019-000267-25 Sponsor Protocol Number: STH20412 Start Date*: 2020-03-17
    Sponsor Name:Sheffield Teaching Hospitals NHS Foundation Trust
    Full Title: Characterisation of a novel regimen of very low-dose aspirin combined with rivaroxaban in patients with chronic coronary syndromes: WILL lOWer dose aspirin be better with rivaroxaban in patients wi...
    Medical condition: Chronic coronary syndrome
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10011078 Coronary artery disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2006-001232-42 Sponsor Protocol Number: RGHT000270 Start Date*: 2006-06-14
    Sponsor Name:Royal Group of Hospitals Trust
    Full Title: The Pharmacogenetics of Aspirin Resistance
    Medical condition: Aspirin resistance: Vascular diseases are common problems and aspirin is used as an anti-platelet drug to prevent thrombosis. However, aspirin's anti-platelet effect may not be uniform in all patie...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-000024-13 Sponsor Protocol Number: aspirin v1 Start Date*: 2006-03-19
    Sponsor Name:Cardiff and Vale NHS Trust
    Full Title: Does Aggressive management with early high dose aspirin reduce the hypercoagulability of platelets following coronary artery bypass grafting?
    Medical condition: Aspirin is an antiplatelet drug that affects the ability of platelets in the blood to bind together and form clots. It is used routinely in patients with or at risk of heart disease and after surg...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2015-000499-89 Sponsor Protocol Number: DK0100 Start Date*: 2015-11-09
    Sponsor Name:Royal College Of Surgeons Ireland
    Full Title: To measure the effects of Aspirin loading dose of 300mgs in healthy controls using AA LTA and the Dynamic Platelet Function Assay (DPFA).
    Medical condition: Cardiovascular disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Completed)
    Trial results: View results
    EudraCT Number: 2008-001071-30 Sponsor Protocol Number: V1 Start Date*: 2010-01-21
    Sponsor Name:Medical University Vienna- Dept. of Pediatric Hemostaselology
    Full Title: Aspirin Resistance in Children after Interventional Cardiac Catheterization: The ARC Study
    Medical condition: children after interventional cardiac catheterization.
    Disease:
    Population Age: Newborns, Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2014-001332-11 Sponsor Protocol Number: IRELANDPILOTV1 Start Date*: 2014-07-30
    Sponsor Name:Royal College of Surgeons
    Full Title: Aspirin for Optimising Pregnancy Outcome in Pregestational Diabetes: Pilot for The IRELAND Study (Investigating the Role of Early Low-dose Aspirin iN preexisting Diabetes)
    Medical condition: Pregestational diabetes represents a high-risk for evolution of preeclampsia (PET), with rates of PET within this group at approximately 20%. The combination of diabetes and preeclampsia places the...
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: IE (Completed)
    Trial results: View results
    EudraCT Number: 2021-003897-30 Sponsor Protocol Number: AERD-COV19 Start Date*: 2022-05-30
    Sponsor Name:Jagiellonian University Medical College
    Full Title: Long-term aspirin therapy as a predictor of decreased susceptibility to SARS-CoV-2 infection in aspirin-exacerbated respiratory disease
    Medical condition: aspirin-exacerbated respiratory disease
    Disease: Version SOC Term Classification Code Term Level
    21.1 10038738 - Respiratory, thoracic and mediastinal disorders 10003534 Aspirin-sensitive asthma LLT
    20.0 10038738 - Respiratory, thoracic and mediastinal disorders 10075084 Aspirin-exacerbated respiratory disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-001589-13 Sponsor Protocol Number: N/A Start Date*: 2012-06-26
    Sponsor Name:Belfast Health and Social Care Trust
    Full Title: The effect of Aspirin on REducing iNflammation in human in vivo model of Acute lung injury (ARENA)
    Medical condition: The intended indication for the product under development is that of acute lung injury.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10038738 - Respiratory, thoracic and mediastinal disorders 10069351 Acute lung injury PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2018-001328-21 Sponsor Protocol Number: ABR65448 Start Date*: 2019-01-08
    Sponsor Name:Leiden University Medical Center
    Full Title: Chronotherapy with aspirin for reduction of cardiovascular disease
    Medical condition: The medical condioton to be investigated is recurrent cardiovascular disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2014-004739-38 Sponsor Protocol Number: NL51093.029.14 Start Date*: 2015-03-09
    Sponsor Name:VU Univeristy Medical Centre
    Full Title: Follow-up of the FRUIT-RCT; aspirin resistance and cardiovascular risk factors in women after recurrent hypertensive disorders in pregnancy
    Medical condition: Hypertensive disorders of pregnancy; aspirin resistance and cardiovascular risk factors.
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-001410-16 Sponsor Protocol Number: 25032013 Start Date*: 2013-07-01
    Sponsor Name:Netherlands Heart Foundation
    Full Title: Effects of low-dose aspirin taken at bedtime vs. on awakening on circadian rhythm of platelet function in healthy subjects
    Medical condition: platelet reactivity
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-004849-33 Sponsor Protocol Number: Asp-Fam-01 Start Date*: 2005-12-21
    Sponsor Name:NHS Greater Glasgow
    Full Title: Prevention of oesophagitis, gastric and duodenal lesions in patients taking antithrombotic low-dose aspirin with famotidine
    Medical condition: Peptic ulceration induced by low-dose aspirin
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2016-000515-32 Sponsor Protocol Number: 2016-623 Start Date*: 2016-04-12
    Sponsor Name:Per Løgstrup Poulsen
    Full Title: Antiplatelet and vascular effects of aspirin in healthy persons and patients with type 2 diabetes.
    Medical condition: Type 2 diabetes and Healthy volunteers
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004861 10012594 Diabetes LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2004-000612-54 Sponsor Protocol Number: 0782-003 Start Date*: 2004-09-11
    Sponsor Name:Merck Sharp & Dohme (Sweden) AB
    Full Title: A Multicenter, Randomized, Parallel-Group, Active-Controlled Double-Blind Study Conducted Under In-House Blinding Conditions to Determine the Incidence of Gastroduodenal Ulcers in Patients With Ost...
    Medical condition: Osteoarthritis (OA) ICD: M19.9 MedDRA: 10031161 Rheumatoid Arthritis (RA) ICD: M06.9 MedDRA: 10039037
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2021-005550-28 Sponsor Protocol Number: NL79129.018.21 Start Date*: 2022-04-14
    Sponsor Name:Amsterdam UMC
    Full Title: Less Bleeding by Omitting Aspirin in Non-ST-segment Elevation Acute Coronary Syndrome Patients
    Medical condition: non-ST-segment elevation acute coronary syndrome
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2008-007875-26 Sponsor Protocol Number: ED08/8782 Start Date*: 2009-08-17
    Sponsor Name:University of Leeds
    Full Title: Modulation of Clot Structure and Platelet Function by Aspirin in Individuals with Diabetes: the role of aspirin dose and Glycaemic control
    Medical condition: Type 1 Diabetes Mellitus
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-005622-31 Sponsor Protocol Number: MEN008 Start Date*: 2006-03-10
    Sponsor Name:University of Dundee
    Full Title: A Proof Of Concept Study To Investigate The Potential Role Of Acetylsalicyclic Acid (Aspirin) As An Anti-Inflammatory Agent For The Treatment Of Asthma
    Medical condition: Asthma
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-003186-40 Sponsor Protocol Number: DM-ASA 001 Start Date*: 2007-09-05
    Sponsor Name:Karolinska Institute
    Full Title: Evaluation of antiplatelet effects of different dosages of aspirin in type 2 diabetic patients.
    Medical condition: Patients with type 2 diabetes mellitus with an indication for aspirin treatment or already on aspirin treatment.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2009-017176-25 Sponsor Protocol Number: WMLREC and BBC LREC Start Date*: 2010-09-08
    Sponsor Name:Sandwell and West Birmingham NHS Trust
    Full Title: Aspirin resistance and heart disease
    Medical condition: Index group 1 : coronary artery disease Index group 2: atrial fibrillation Control group 1: Diabetes/hypertension/hypercholesterolaemia Control group 2: Healthy subjects
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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