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Clinical trials for Blepharospasm

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44364   clinical trials with a EudraCT protocol, of which   7388   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    5 result(s) found for: Blepharospasm. Displaying page 1 of 1.
    EudraCT Number: 2012-004821-26 Sponsor Protocol Number: MRZ60201_3074_1 Start Date*: 2013-04-01
    Sponsor Name:Merz Pharmaceuticals GmbH
    Full Title: Prospective, double-blind, placebo-controlled, randomized, parallel-group, multi-center study with an open-label extension period to investigate the efficacy and safety of two different doses of NT...
    Medical condition: Bilateral Blepharospasm (BEB)
    Disease: Version SOC Term Classification Code Term Level
    15.1 10015919 - Eye disorders 10005159 Blepharospasm PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Completed)
    Trial results: View results
    EudraCT Number: 2007-000697-23 Sponsor Protocol Number: MRZ 60201-0703/1 Start Date*: 2007-07-10
    Sponsor Name:Merz Pharmaceuticals GmbH
    Full Title: Prospective, single-arm, single-center, open-label trial to investigate the tolerability of NT 201 and quality of life of patients in the treatment of blepharospasm with shortened injection intervals
    Medical condition: Blepharospasm
    Disease: Version SOC Term Classification Code Term Level
    9.1 10005159 Blepharospasm LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-018345-64 Sponsor Protocol Number: 38/10 Start Date*: 2011-03-23
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: Evaluation of the efficacy of Xeomin in the treatment of cervical dystonia (CD) and blepharospasmus (BS) in patients who did not respond to treatment with Botox.
    Medical condition: cervical dystonia, blepharospasmus (BS)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10005159 PT
    9.1 10064124 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-006170-10 Sponsor Protocol Number: ALLBL001 Start Date*: 2006-06-22
    Sponsor Name:Allergan Limited
    Full Title: A Double-Blind, Randomised, Parallel group, Safety and Efficacy Pilot Study Comparing Two Botulinum Toxin Type-A Products in the Treatment of Blepharospasm
    Medical condition: Blepharospasm is a focal dystonia characterised by excessive involuntary contraction of the orbicularis oculi muscles. In severe cases, tonic eyelid closure can lead to functional blindness and can...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2011-002174-23 Sponsor Protocol Number: SMART_5 Start Date*: 2011-11-21
    Sponsor Name:Lofarma S.p.A.
    Full Title: A dose Finding Study of the Efficacy of LAIS Grass tablets in patients suffering from grass pollen-induced allergic rhinoconjunctivitis
    Medical condition: allergic rhinoconjunctivitis
    Disease: Version SOC Term Classification Code Term Level
    14.0 10015919 - Eye disorders 10001728 Allergic rhinoconjunctivitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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