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Clinical trials for Bone grafting

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44347   clinical trials with a EudraCT protocol, of which   7375   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    21 result(s) found for: Bone grafting. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2012-005664-10 Sponsor Protocol Number: BMP2/1 Start Date*: 2015-09-30
    Sponsor Name:UZ Leuven Orthopedic research
    Full Title: InductOs® (rhBMP-2; dibotermin alfa) vs. autologous bone grafting for the treatment of nonunion of the docking site in tibial bone transport
    Medical condition: fractured non-healing tibia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2006-001725-25 Sponsor Protocol Number: RSA-HIP220306 Start Date*: 2007-08-09
    Sponsor Name:GREATER GLASGOW HEALTH BOARD
    Full Title: REVISION HP REPLACEMENT - ACETABULAR IMPACTION GRAFTING - A RADIOSTEREOMETRIC COMPARISON BETWEEN FRESH FROZEN ALLOGRAFT AND MARROW-DEPLETED BONE WITH CALCIUM PHOSPHATE PLUS OR MINUS BONE MORPHOGENI...
    Medical condition: REVISION HIP REPLACEMENT
    Disease: Version SOC Term Classification Code Term Level
    9.1 10057128 Revision of hip arthroplasty LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2021-001708-14 Sponsor Protocol Number: ABOGRAFT-01 Start Date*: 2021-06-29
    Sponsor Name:Region Östergötland
    Full Title: Antibiotic Impregnated Bone Graft to reduce infection in hip replacement. The ABOGRAFT trial
    Medical condition: Patients scheduled for any type of hip arthroplasty requiring bone grafting
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2018-004046-41 Sponsor Protocol Number: 273551 Start Date*: 2021-12-09
    Sponsor Name:University of Bergen,
    Full Title: A multicentre clinical trial; Alveolar bone augmentation using Mesenchymal Stem Cells and biphasic calcium phosphate granules prior to dental implants
    Medical condition: Patients in need of dental implant(s) in the upper and lower jaws with presence of bone defects with loss in vertical height and < than 4 mm in lateral width
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-003688-30 Sponsor Protocol Number: CS I-040101/02 Start Date*: 2007-02-27
    Sponsor Name:Kuros Biosurgery AG
    Full Title: A phase 2 randomized, controlled, open-label (dose-blinded), multi-center, dose-finding study of the safety and efficacy of I-0401 in the treatment of patients with fractures of the tibial plateau ...
    Medical condition: Fractures of the tibial plateau requiring grafting
    Disease: Version SOC Term Classification Code Term Level
    13.1 10028395 - Musculoskeletal and connective tissue disorders 10024956 Lower limb fractures HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) DE (Completed) ES (Completed) IT (Completed) FR (Completed) HU (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-001227-39 Sponsor Protocol Number: 779322 Start Date*: 2019-12-11
    Sponsor Name:University of Bergen, Faculty of Medicin, Department of Clinical Dentistry
    Full Title: A randomized controlled clinical trial to assess the efficacy of a combination of autologous mesenchymal stem cells and biomaterial in jaw bone regeneration prior to dental implant placement in com...
    Medical condition: Patients in need of dental implant(s) in the upper and lower jaws with presence of bone defects with loss in vertical height and < than 4 mm in lateral width
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004859 10005958 Bone disorder NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed) NO (Completed) ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-001286-42 Sponsor Protocol Number: ABI 55-0603-1 Start Date*: 2006-09-20
    Sponsor Name:Aastrom Biosciences, Inc
    Full Title: Multi-center, Multi-national Clinical Trial of the Application of Tissue Repair Cell (TRC) Therapy of Osteonecrosis in the Femur Head
    Medical condition: Osteonecrosis of the femur head
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-002002-46 Sponsor Protocol Number: 2012-BMP1-2 Start Date*: 2013-05-07
    Sponsor Name:Universitätsklinik für Zahn-, Mund- und Kieferheilkunde, Med Uni Graz, Department für zahnärztliche Chirurgie
    Full Title: A phase III, randomized, controlled clinical pilot trial of lateral ridge augmentation using autogenous bone blocks or xenogenic bone block grafts loaded with recombinant human bone morphogenic pro...
    Medical condition: Difference of percepetion/acceptance in patients trated with autogonous bone blocks or xenogenic bone block loaded with BMP2 to create a sufficent bonesituation Difference in quantity and quality...
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10064143 Dental implantation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2012-003139-50 Sponsor Protocol Number: Maxillo1 Start Date*: Information not available in EudraCT
    Sponsor Name:University of Bergen, Faculty of medicin and dentistry, Dep. of Clinical Dentistry
    Full Title: International, multicenter phase II uncontrolled prospective clinical trial: Jaw bone reconstruction using a combination of biomaterial and autologous mesenchymal stem cells prior to dental impla...
    Medical condition: Men and women aged 18 years or more requiring jaw bone reconstruction prior to dental implant placement based on clinical and radiological examinations (CBCT Cone beam CT imaging). Areas suitable ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-006652-35 Sponsor Protocol Number: ML 20958 Start Date*: 2007-09-28
    Sponsor Name:Queen Mary University of London
    Full Title: A pilot study to evaluate of the impact on bone density during treatment with mycophenolate mofetil, daclizumab in combination with ciclosporin converted to sirolimus with steroid as mainstay immun...
    Medical condition: Renal Transplantation
    Disease: Version SOC Term Classification Code Term Level
    9.1 10038533 Renal transplant PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2018-000299-13 Sponsor Protocol Number: NVD003-CLN01 Start Date*: 2018-05-17
    Sponsor Name:Novadip Biosciences
    Full Title: A prospective multicentre single-arm study in adults to evaluate the safety and preliminary efficacy of the autologous 3D osteogenic implant NVD-003 for bone reconstruction for the treatment of rec...
    Medical condition: Patients with documented recalcitrant lower limb nonunion, meaning a single, meta- and/or diaphyseal nonunion defect of femur or tibia after at least one failed reconstructive surgical attempt.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Trial now transitioned) LU (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2008-002807-21 Sponsor Protocol Number: VitaD-1 Start Date*: 2008-10-15
    Sponsor Name:MUW, Universitätsklinik für Innere Medizin III, Abteilung für Nephrologie und Dialyse
    Full Title: VITA-D: Cholecalciferol substitution in vitamin D deficient kidney transplant recipients: A randomized, placebo-controlled study to evaluate the posttransplant outcome
    Medical condition: Vitamin D deficiency in kidney transplant recipients
    Disease: Version SOC Term Classification Code Term Level
    9.1 10047626 Vitamin D deficiency LLT
    9.1 10023438 Kidney transplant LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2022-001282-12 Sponsor Protocol Number: NVD003-CLN02-CPT Start Date*: 2022-08-02
    Sponsor Name:Novadip Biosciences
    Full Title: A proof-of-concept study with NVD-003, an autologous osteogenic bone graft, in the treatment of congenital pseudarthrosis of the tibia in pediatric patients
    Medical condition: congenital pseudarthrosis of the tibia (CPT)
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: BE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2004-005055-33 Sponsor Protocol Number: ML17443 Start Date*: 2005-09-01
    Sponsor Name:Barts and the London NHS Trust
    Full Title: Evaluating the safety and efficacy of mycophenolate mofetil, daclizumab and a single, initial week of corticosteroids in combination with tacrolimus or sirolimus with continued steroid as mainstay ...
    Medical condition: Renal Transplantation
    Disease: Version SOC Term Classification Code Term Level
    7.1 10038533 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-001845-34 Sponsor Protocol Number: AMBIHOW Start Date*: 2011-09-15
    Sponsor Name:AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI
    Full Title: LIPOSOMAL AMPHOTERICIN B (AMBISOME) 10 mg/kg once a week for 10 weeks as maintenance antifungal therapy for Proven/Probable Invasive Fungal Infection in hematologic patients with Acute Myeloid Leuk...
    Medical condition: Proven/Probable Invasive Fungal Infection in hematologic patients with Acute Myeloid Leukaemia and/or in Allogeneic Hematopoietic Stem Cell Transplant recipients.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10061730 Bone marrow transplant PT
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10000886 Acute myeloid leukemia LLT
    14.1 10005329 - Blood and lymphatic system disorders 10028484 Mycoses fungoides HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-005526-22 Sponsor Protocol Number: V4 Start Date*: 2012-05-14
    Sponsor Name:Medizinische Universität Wien
    Full Title: Tissue concentration of cefazolin and linezolid in sternal spongiosa in elective coronary artery bypass grafting: an in-vivo microdialysis study
    Medical condition: perioperative antibiotic prophylaxis during coronary artery bypass grafting
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10036894 Prophylactic antibiotic therapy LLT
    14.1 10042613 - Surgical and medical procedures 10011077 Coronary artery bypass PT
    14.1 10042613 - Surgical and medical procedures 10064736 Antibiotic prophylaxis PT
    14.1 10007541 - Cardiac disorders 10011078 Coronary artery disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-003561-15 Sponsor Protocol Number: MYSTEP1 Start Date*: 2016-08-30
    Sponsor Name:University Hospital of Tuebingen
    Full Title: Safety and Tolerance of Immunomodulating Therapy with Donor-specific Mesenchymal Stem Cells in Pediatric Living-Donor Liver Transplantation
    Medical condition: Side effects of life-long immunosuppressive medication account for major morbidity after pediatric liver transplantation and impair quality of life. In-vivo and in-vitro studies have shown that MSC...
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004865 10024716 Liver transplantation LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-024297-19 Sponsor Protocol Number: TJB1016P1 Start Date*: 2011-09-13
    Sponsor Name:CHU de Liege
    Full Title: Allogeneic hematopoietic cell transplantation from HLA-matched donors after reduced-intensity conditioning: a phase II randomized study comparing 2 GVHD prophylaxis regimen
    Medical condition: Hematologic malignancies treated by reduced-intensity conditioning allogeneic transplants.
    Disease: Version SOC Term Classification Code Term Level
    18.0 10042613 - Surgical and medical procedures 10001756 Allogenic bone marrow transplantation therapy PT
    18.0 100000004870 10018799 GVHD LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-003914-38 Sponsor Protocol Number: 2021-003914-38 Start Date*: 2022-02-14
    Sponsor Name:Fundación Pública Andaluza para la Gestión de la Investigación
    Full Title: Efficacy and safety of different antimicrobial DURATions for the treatment of infections associated with Osteosynthesis Material implanted after long bone fractures (DURATIOM). Phase 4 pragmatic mu...
    Medical condition: Patients with long bone fractures who have had osteosynthesis material implanted to stabilize and assist fracture healing and meet the criteria for Infections associated with osteosynthesis material
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10021881 Infections and infestations SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-002495-20 Sponsor Protocol Number: 000108 Start Date*: 2018-02-15
    Sponsor Name:Ferring Pharmaceuticals A/S
    Full Title: A Multi-Center, Randomized, Assessor-Blind, Controlled Trial Comparing the Occurrence of Major Adverse Cardiovascular Events (MACEs) in Patients with Prostate Cancer and Cardiovascular Disease Rece...
    Medical condition: Advanced Prostate Cancer
    Disease: Version SOC Term Classification Code Term Level
    21.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10071119 Hormone-dependent prostate cancer PT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: SK (Completed) CZ (Completed) DE (Completed) GB (GB - no longer in EU/EEA) FR (Completed) GR (Completed) FI (Completed) PL (Completed)
    Trial results: View results
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