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Clinical trials for Bupivacaine

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   43871   clinical trials with a EudraCT protocol, of which   7290   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    162 result(s) found for: Bupivacaine. Displaying page 1 of 9.
    1  2  3  4  5  6  7  8  9  Next»
    EudraCT Number: 2010-020020-21 Sponsor Protocol Number: AN10/9307 Start Date*: 2011-07-12
    Sponsor Name:Leeds Teaching Hospitals Trust
    Full Title: Comparison of the ED95 dose of 0.075% and 0.1% bupivacaine for labour analgesia in primigravida
    Medical condition: Patients pregnant for the first time(primigravida)in early labour requesting epidural analgesia for pain relief.
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-002843-32 Sponsor Protocol Number: 54015 Start Date*: 2016-09-20
    Sponsor Name:
    Full Title: The haemodynamic effects of spinal anaesthesia with versus without sufentanil added to bupivacaine heavy
    Medical condition: Patient undergoing surgery for which they receive spinal anaesthesia
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-000961-22 Sponsor Protocol Number: 16/009U Start Date*: 2016-11-14
    Sponsor Name:Ziekenhuis Oost-Limburg
    Full Title: Quality of analgesia after ultrasound-guided specific blocks of the distal tibial and deep peroneal nerves with 15 mL of a 50:50 mixture bupivacaine 0.5% and liposome bupivacaine (Exparel®) )1.3% ...
    Medical condition: Hallux valgus
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2022-000857-10 Sponsor Protocol Number: NA Start Date*: 2022-05-16
    Sponsor Name:CHU de Liège
    Full Title: Isobaric versus hyperbaric intrathecal bupivacaine: influence of baricity on blood pression variation during elective total knee arthroplasty: a randomized clinical trial.
    Medical condition: Total knee arthroplasty
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-001719-39 Sponsor Protocol Number: INN-CB-002 Start Date*: 2008-07-23
    Sponsor Name:Innocoll Technologies
    Full Title: A Phase II, Single Dose, Blinded, Prospective Study to Investigate the Efficacy and Safety of the CollaRx® Bupivacaine Implant in Women following Abdominal Hysterectomy or other Nonlaparoscopic Ben...
    Medical condition: To investigate the efficacy and safety of the CollaRx Bupivacaine Implant in women following abdominal hysterectomy or other nonlaparoscopic benign gynecological procedure
    Disease: Version SOC Term Classification Code Term Level
    9.1 10044080 Total abdominal hysterectomy LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2015-001559-55 Sponsor Protocol Number: 15/022U Start Date*: 2015-05-28
    Sponsor Name:Ziekenhuis Oost-Limburg, Departement of Anesthesia
    Full Title: Quality of analgesia after interscalene block with 5 mL of bupivacaine 0.25% and 10 mL of Exparel® (133 mg) vs. 15 mL of 0.25% bupivacaine after arthroscopic shoulder surgery
    Medical condition: Postoperative pain after arthroscopic shoulder surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-006196-19 Sponsor Protocol Number: OC003SB Start Date*: 2012-02-28
    Sponsor Name:Clinical Research Centre, Hvidovre University Hospital
    Full Title: Clinical Trials with lozenge as local anaesthesia as treatment of oral pain in burning mouth syndrome and Sjögrens syndrome
    Medical condition: Oral pain caused by the illnesses burning mouth syndrome, Sjögren's syndrome and lichen planus
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2005-006096-12 Sponsor Protocol Number: 87179098 Start Date*: 2006-07-06
    Sponsor Name:Karolinska University Hospital, Huddinge
    Full Title: Can peroperative subcutaneous, injection of bupivacaine with adrenaline decrease the postoperative need or opiates after cesarean section?
    Medical condition: Postoperative pain after cesarean section.
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-003154-32 Sponsor Protocol Number: N/A Start Date*: 2017-09-18
    Sponsor Name:University of Leeds
    Full Title: SPAARK: Study of Peri-Articular Anaesthetic for Replacement of the Knee. The clinical and cost effectiveness of peri-articular liposomal bupivacaine compared with bupivacaine hydrochloride alone fo...
    Medical condition: Local anaesthetic for patients undergoing knee replacement surgery for arthritis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2010-021446-21 Sponsor Protocol Number: 00001 Start Date*: 2010-12-28
    Sponsor Name:Per Rosenberg
    Full Title: Laskimonsisäisesti annetun rasvaemulsion kyky sitoa bupivakaiinia verenkierrossa
    Medical condition: The study is performed on healthy volunteers, investigating lipid resuscitation from local anesthetic intoxication.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10066766 Acute drug intoxication LLT
    Population Age: Adults Gender: Male
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-002862-15 Sponsor Protocol Number: BupivacTons20 Start Date*: 2021-03-03
    Sponsor Name:Nordland Hospital. Bodø. Dep of Surgery
    Full Title: Can topical anaesthesia with bupivacaine reduce pain after tonsillectomy?
    Medical condition: Local pain after tonsillectomy, both at rest and during swallowing. Assessed by self-reporting at 1, 2, 3, 4, 5, 6 hours and 1,2,4 and 6 days after surgery.
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-000393-34 Sponsor Protocol Number: R03003 Start Date*: 2015-06-01
    Sponsor Name:Central Manchester University Hospitals NHS Foundation Trust
    Full Title: Clinical trial of the investigational medicinal product, local anaesthetic levo-bupivacaine in infants 3 - 6 months post natal age.
    Medical condition: Pain relief in infants undergoing surgical repair of bladder exstrophy
    Disease: Version SOC Term Classification Code Term Level
    18.0 10042613 - Surgical and medical procedures 10054799 Perioperative analgesia PT
    18.0 10042613 - Surgical and medical procedures 10036276 Postoperative analgesia PT
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-000538-19 Sponsor Protocol Number: CLIN004-0009 Start Date*: 2005-04-21
    Sponsor Name:DURECT Corporation
    Full Title: Protocol CLIN004−0009 (February 02, 2005): A Pharmacodynamic/Pharmacokinetic Study of SABER−Bupivacaine and/or Bupivacaine HCl Administered Intra−operatively During Open Inguinal Hernia Repair unde...
    Medical condition: Inguinal hernia repair
    Disease: Version SOC Term Classification Code Term Level
    10022020
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-011829-13 Sponsor Protocol Number: AN09/8905 Start Date*: 2009-11-02
    Sponsor Name:University of Leeds
    Full Title: What is the ED95 dose for bupivacaine for supraclavicular brachial plexus block using ultrasound?
    Medical condition: Patients presenting for routine upper limb surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-004307-20 Sponsor Protocol Number: Start Date*: 2012-02-09
    Sponsor Name:Reino Pöyhiä
    Full Title: Comparison of periosteal and subcutaneous infusions of articaine and bupivacaine in treatment of acute pain after sternotomy
    Medical condition: Patients undergoing elective open aortic or mitral valve, atrial septal defect or myxoma surgery
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10048935 Open heart surgery LLT
    14.1 10022117 - Injury, poisoning and procedural complications 10054711 Postoperative pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-011828-64 Sponsor Protocol Number: FRS-AN2009-03-26 Start Date*: 2009-08-03
    Sponsor Name:Anesthesiological dep., Hospital of Frederikssund
    Full Title: Spinalanæstesi til knæartroskopi: Kan tilsætning af Lidokain til Bupivacain forkorte blokadens varighed?
    Medical condition: Duration of nerve blockade after spinal anesthesia with either bupivacaine or a mixture of bupivacaine/lidocaine.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-003275-19 Sponsor Protocol Number: 402-C-322 Start Date*: 2013-01-29
    Sponsor Name:Pacira Pharmaceuticals, Inc.
    Full Title: A Phase 3, Multicenter, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Study to Assess the Efficacy and Safety of Intercostal Nerve Block with Liposome Bupivacaine in Subjects Undergo...
    Medical condition: Intercostal Nerve Block for Posterolateral Thoracotomy
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004865 10038286 Regional nerve block LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) PL (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2018-001191-38 Sponsor Protocol Number: TYKS/LeLiBu/1-2 Start Date*: 2020-03-03
    Sponsor Name:Turku University Hospital
    Full Title: Levobupivacaine versus Liposomal Bupivacaine (Exparel®) for Treatment of Pain and Disability in Lateral Epicondylitis – Off-Label, Investigator Initiated Randomized, Controlled, Double-Blind Cross-...
    Medical condition: Lateral epicondylitis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-003010-26 Sponsor Protocol Number: B076201627677 Start Date*: 2018-01-11
    Sponsor Name:Centre Hospitalier Universitaire Saint Pierre , ULB
    Full Title: Hyperbaric Bupivacaine Versus Hyperbaric Prilocaine 2% for Cesarean Section Under Spinal Anesthesia: a Randomised and Controlled Clinical Trial
    Medical condition: Parturients undergoing an elective caesarean section performed under spinal anaesthesia
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: BE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2015-002402-36 Sponsor Protocol Number: 651 Start Date*: 2015-08-27
    Sponsor Name:Sint Maartenskliniek
    Full Title: Pharmacokinetic Profile of Liposome Bupivacaine (Exparel®) after Perineural Admission in the Interscalene Groove for Primary Total Shoulder Arthroplasty.
    Medical condition: patients receiving a primary total shoulder arthroplasty
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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