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Clinical trials for Cognition

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   43881   clinical trials with a EudraCT protocol, of which   7295   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    494 result(s) found for: Cognition. Displaying page 1 of 25.
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    EudraCT Number: 2006-004435-30 Sponsor Protocol Number: SC06-02 Start Date*: 2006-10-31
    Sponsor Name:FONDAZIONE SANTA LUCIA
    Full Title: Protocol of study for the evaluation of the efficacy of rivastigmine on cognitive and behavioural disorders, following traumatic brain injury TBI in chronic patients.
    Medical condition: Patients with cognitive and behavioural disorders following severe TBI and other severe acquired brain injury Glasgow Coma Scale GCS lower or equal 8
    Disease: Version SOC Term Classification Code Term Level
    9.1 10057668 Cognitive disorder LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-003331-10 Sponsor Protocol Number: HC03 Start Date*: 2017-10-16
    Sponsor Name:Leiden University
    Full Title: Acute effects of 40 mg cortisol on emotion and cognition.
    Medical condition: None.
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2011-002070-23 Sponsor Protocol Number: EEGrofl Start Date*: 2011-10-12
    Sponsor Name:Maastricht University Medical Center
    Full Title: Effects of roflumilast on cognition in healthy adults: a behaviour-EEG study
    Medical condition: None; this proof-of-principle study will examine the cognition enhancing effects of roflumilast in healthy subjects
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2014-000254-11 Sponsor Protocol Number: 33375 Start Date*: 2014-03-28
    Sponsor Name:Department of Neurology
    Full Title: ROLE OF ENDOTHELIAL INFLAMMATION IN DEMYELINATING DISEASES OF THE CENTRAL NERVOUS SYSTEM
    Medical condition: Mulple Sclerosis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2005-005989-37 Sponsor Protocol Number: 308841 Start Date*: 2006-03-29
    Sponsor Name:Schering Oy
    Full Title: CogniMS: observational study to assess cognition in patients with early Multiple Sclerosis
    Medical condition: Observational Study to assess cognition in patients with early Multiple Sclerosis. Relapsing-Remitting MS-patients diagnosed within 2 years and who have started the Betaferon treatment (interferon-...
    Disease:
    Population Age: Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-024659-10 Sponsor Protocol Number: 2010-024659-10 Start Date*: 2011-08-03
    Sponsor Name:Rigshospitalet
    Full Title: Can stimulation of the nNOS system in muscle disease with nNOS insufficiency improve heart and skeletal muscle function and cognition?
    Medical condition: Muscular dystrophy with nNOS insufficiency
    Disease: Version SOC Term Classification Code Term Level
    14.0 10028395 - Musculoskeletal and connective tissue disorders 10028301 Muscle disorder NOS LLT
    Population Age: Adults Gender: Male
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2020-005073-28 Sponsor Protocol Number: ParKMetil/001 Start Date*: 2021-12-28
    Sponsor Name:Universidad Rey Juan Carlos
    Full Title: Double-blind, randomized, crossover design for evaluation of efficacy and safety of methylphenidate in cognition in patients with Parkinson's disease using electrophysiological measures
    Medical condition: Cognition
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-012340-16 Sponsor Protocol Number: EPU P49 Start Date*: 2009-07-20
    Sponsor Name:Maastricht University
    Full Title: Effects of morning versus evening dose of hydroxyzine 50 mg on cognition in healthy subjects
    Medical condition: To assess the morning versus evening dose effect of hydroxyzine 50 mg on cognition in healthy volunteers
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-000504-37 Sponsor Protocol Number: 2020PI215 Start Date*: 2021-04-01
    Sponsor Name:CHRU DE NANCY
    Full Title: Characterization by PET-CT with 18F-FDG of brain lesions in young subjects with sequential psycho-cognitive disorders following severe COVID19
    Medical condition: young subjects with sequential psycho-cognitive disorders in the aftermath of severe COVID-19
    Disease: Version SOC Term Classification Code Term Level
    23.1 100000004863 10084547 Exposure to COVID-19 LLT
    21.1 10029205 - Nervous system disorders 10057668 Cognitive disorder PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-001572-19 Sponsor Protocol Number: 14122A Start Date*: 2011-12-21
    Sponsor Name:H. Lundbeck A/S
    Full Title: Randomised, double-blind, parallel-group, placebo-controlled, fixed dose study on the efficacy of Lu AA21004 on cognitive dysfunction in adult patients with Major Depressive Disorder (MDD)
    Medical condition: -Cognitive dysfunction -Major Depressive Disorder (MDD)
    Disease: Version SOC Term Classification Code Term Level
    14.0 10029205 - Nervous system disorders 10057668 Cognitive disorder PT
    14.0 10037175 - Psychiatric disorders 10025453 Major depressive disorder NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SK (Completed) FI (Completed) LV (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-005841-13 Sponsor Protocol Number: 65705 Start Date*: 2007-01-25
    Sponsor Name:Gedeon Richter Plc
    Full Title: Multicenter, open-label study to investigate the efficacy and safety of Cavinton Forte (vinpocetine) tablet in patients with mild cognitive impairment (MCI).
    Medical condition: Mild cognitive impairment
    Disease: Version SOC Term Classification Code Term Level
    9.1 10009846 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: View results
    EudraCT Number: 2009-014283-19 Sponsor Protocol Number: 575/09 Start Date*: 2009-08-04
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: Effect of remifentanil on postoperative cognitive function in patients undergoing major abdominal surgery
    Medical condition: Elderly patients with risk of post operative cognitive dysfunction.
    Disease: Version SOC Term Classification Code Term Level
    12.0 10009845 Cognitive disturbance LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-003390-95 Sponsor Protocol Number: WN28745 Start Date*: 2014-02-26
    Sponsor Name:F. Hoffmann-La Roche Ltd
    Full Title: A Phase III, randomized, double-blind, placebo-controlled, parallel-group, multicenter efficacy and safety study of Gantenerumab in patients with Mild Alzheimer’s disease: Part II: Open-label exten...
    Medical condition: MILD ALZHEIMER’S DISEASE
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004852 10001897 Alzheimer's disease (incl subtypes) HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) DE (Completed) SE (Completed) ES (Completed) PT (Completed) IT (Completed) NL (Completed) BE (Completed) HU (Completed) FI (Completed) BG (Completed) DK (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2018-004729-97 Sponsor Protocol Number: 2018-PWL Start Date*: 2019-08-16
    Sponsor Name:Dutch Growth Research Foundation
    Full Title: Randomized, controlled growth hormone study in children and adolescents with a Prader-Willi-like phenotype, followed by a two year open-label growth hormone study - effects on body composition, gro...
    Medical condition: Prader-Willi-like phenotype
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004848 10018747 Growth hormone LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-003945-40 Sponsor Protocol Number: EPU-P112 Start Date*: 2019-04-10
    Sponsor Name:Maastricht University
    Full Title: EFFECTS OF VAPORISED CANNABIS, WITH AND WITHOUT CBD, ON DRIVING AND COGNITION
    Medical condition: This study will look at the differential effects of variations in cannabis chemovars on driving ability and cognition
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-000517-31 Sponsor Protocol Number: ANST_2014_KET Start Date*: 2014-06-10
    Sponsor Name:Leiden University Medical Center
    Full Title: Effect of perioperative ketamine on postoperative outcome – a randomized placebo-controlled trial
    Medical condition: Postoperative cognitive state
    Disease: Version SOC Term Classification Code Term Level
    17.0 10022117 - Injury, poisoning and procedural complications 10049987 Confusion postoperative PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-005010-37 Sponsor Protocol Number: 62 Start Date*: 2005-08-16
    Sponsor Name:Suffolk Mental Health Partnerships Trust
    Full Title: Enhancing cognition in bipolar disorder
    Medical condition: Bipolar affective disorder, currently in remission
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-003102-10 Sponsor Protocol Number: modafinil01 Start Date*: 2009-01-23
    Sponsor Name:fonds NutsOhra
    Full Title: The effect of modafinil on fatigue, cognition and functional connectivity in low-grade glioma patients: a double-blind randomized trial.
    Medical condition: fatigue in low-grade glioma patients
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-000101-24 Sponsor Protocol Number: 200453 Start Date*: 2013-09-05
    Sponsor Name:University of Helsinki
    Full Title: The effect of antiherpes medication with valaciclovir on cognition and function in patients with Alzheimer disease The HEVALITZ Study - Pilot study
    Medical condition: Alzheimer disease
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: FI (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-004109-27 Sponsor Protocol Number: 2.12.05 Start Date*: 2006-03-24
    Sponsor Name:Neuropsychiatric clinic
    Full Title: A double-blind, placebo-controlled multi-centre trial of memantine in patients with Parkinsons’ disease dementia or dementia with Lewy bodies
    Medical condition: Parkinsons disease (PD)and dementia with Lewy bodies (DLB) are both common disease of the elderly. The majority of patients who survive for more than 10 years with PD eventually develope dementia ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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