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Clinical trials for Concentration effect

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44363   clinical trials with a EudraCT protocol, of which   7387   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    1,460 result(s) found for: Concentration effect. Displaying page 1 of 73.
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    EudraCT Number: 2017-005068-16 Sponsor Protocol Number: 221181 Start Date*: 2018-02-14
    Sponsor Name:University Hospital of Aarhus
    Full Title: Measurement of Acetylsalicylic acid Concentration and Effect - MACE
    Medical condition: Healthy volunteers (Prophylaxis of arterial thrombosis)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10022891 - Investigations 10022891 Investigations SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2019-005011-73 Sponsor Protocol Number: PI2019_843_0018 Start Date*: 2020-03-11
    Sponsor Name:CHU Amiens-Picardie
    Full Title: Determination of a trough serum concentration of ofloxacin associated to increase in side effects frequency in elderly treated for bone and joint infection
    Medical condition: bone and joint infection
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-003281-84 Sponsor Protocol Number: EXCRETE Start Date*: 2018-03-27
    Sponsor Name:Academical Medical Centre, department of internal
    Full Title: The Effect of UrsodeoXyCholicacid (UDCA) and ezetimibe on total faecal steRol ExcreTion and plasma lipid lEvels
    Medical condition: Familial hypercholesterolemia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-000576-33 Sponsor Protocol Number: RBN 542 Start Date*: 2006-06-13
    Sponsor Name:St Helens & Knowsley Hospitals NHS Trust [...]
    1. St Helens & Knowsley Hospitals NHS Trust
    2. Universtiy of Liverpool
    Full Title: Pilot Study to investigate the role of Glutamine in the early protective stress response
    Medical condition: Critical Illness
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-000882-36 Sponsor Protocol Number: PAD20001 Start Date*: 2004-08-05
    Sponsor Name:GlaxoSmithKine Research & Development Limited
    Full Title: A multi-centre, two-staged with interim analysis, parallel, randomised, double blind, placebo-controlled, dose ranging study of the safety, tolerability, and effects on plasma high-density lipoprot...
    Medical condition: Treatment of dyslipidaemia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) FI (Completed) LT (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2020-003174-50 Sponsor Protocol Number: ALBUCEF Start Date*: 2021-01-28
    Sponsor Name:Medical University of Vienna Department of Cardiac Thoracic Vascular Anesthesia and Intensive Care Medicine
    Full Title: The Effect of Albumin Levels on Pharmacokinetics of Cefazolin in Adult Cardiac Surgery: A Prospective, Randomized, Open-label, Parallel-group Pharmacokinetic Study
    Medical condition: effect of hypoalbuminemia on pharmacokinetics of cefazolin
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2006-001146-13 Sponsor Protocol Number: A 001 Start Date*: 2006-05-18
    Sponsor Name:University Hospital of Heidelberg
    Full Title: "Investigation of Caspofungin Plasma Concentration and Pharmacokinetic for the Improvement of the Antifungal Therapy in Patients of Surgical Intensive Care Unit"
    Medical condition: hospitalised patients
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2019-002910-37 Sponsor Protocol Number: TEA Start Date*: 2019-10-07
    Sponsor Name:Erasmus MC
    Full Title: Study on the pharmacokinetic interaction between green tea and tamoxifen in patients with breast cancer. “the TEA study”
    Medical condition: Breast cancer
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-001777-13 Sponsor Protocol Number: 1H_lac_acc Start Date*: 2014-09-10
    Sponsor Name:Radboud umc
    Full Title: The effect of insulin-induced hypoglycemia on brain lactate accumulation and regional cerebral blood flow in patients with type 1 diabetes mellitus with and without hypoglycemia unawareness and non...
    Medical condition: Type 1 Diabetes Mellitus and Hypoglycemia Unawareness
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-001243-27 Sponsor Protocol Number: 77108 Start Date*: 2021-12-09
    Sponsor Name:Radboudumc
    Full Title: Effect of oral magnesium supplementation on insulin sensitivity in people with type 2 diabetes
    Medical condition: People with type 2 diabetes mellitus who are treated with insulin and have a low serum magnesium concentration
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2019-001314-41 Sponsor Protocol Number: 69501 Start Date*: 2019-05-06
    Sponsor Name:
    Full Title: Kinetics of ivacaftor at Switch Orkambi Symkevi study
    Medical condition: Cystic fibrosis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2012-004622-14 Sponsor Protocol Number: LPS_concmed_controlled Start Date*: 2013-02-01
    Sponsor Name:Radboud University Nijmegen Medical Centre
    Full Title: Concentration/meditation as a novel means to limit inflammation: a randomized controlled pilot study
    Medical condition: Possibe future indications: inflammatory conditions in general, auto-immune diseases
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2017-001439-37 Sponsor Protocol Number: MACSevoPregabalin Start Date*: 2019-09-16
    Sponsor Name:Medical University of Vienna, Department of Anaesthesia, General Critical Care and Pain Management
    Full Title: The effect of pregabalin on the minimal alveolar concentration of sevoflurane
    Medical condition: This study aims to investigate the effect of clinically used doses of Pregabalin on the minimum alveolar concentration of sevoflurane to provide more information to clinicians using this adjunctive...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2019-002232-82 Sponsor Protocol Number: KIH18001 Start Date*: 2019-07-25
    Sponsor Name:Karolinska Institutet
    Full Title: Downstream targets of SSRI effect in treatment of Major Depressive Disorder
    Medical condition: Major depressive disorder (MDD)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2012-003011-58 Sponsor Protocol Number: CACZ885M2301S2 Start Date*: 2012-12-10
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A randomized, double-blind, placebo-controlled, event-driven trial of quarterly subcutaneous canakinumab in the prevention of recurrent cardiovascular events among stable post-myocardial infarction...
    Medical condition: atherosclerosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) HU (Completed) IT (Prematurely Ended) SK (Completed)
    Trial results: View results
    EudraCT Number: 2020-002621-29 Sponsor Protocol Number: tacpat Start Date*: 2021-06-08
    Sponsor Name:oslo university hospital
    Full Title: Effect of patiromer on pharmacokinetics of immunosuppressive drugs in renal transplant recipients
    Medical condition: hyperkalemia transplantation immunosuppression
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-001281-11 Sponsor Protocol Number: 20CH065 Start Date*: 2020-03-30
    Sponsor Name:CHU de Saint Etienne
    Full Title: Evaluation of the concentration/viral effect relationship of hydroxychloroquine in COVID-19 patients in the intensive care unit.
    Medical condition: covid-19
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004848 10070267 SARS virus test positive LLT
    21.1 10042613 - Surgical and medical procedures 10022519 Intensive care PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2014-005200-13 Sponsor Protocol Number: SafePed002 Start Date*: 2015-07-09
    Sponsor Name:Ghent University
    Full Title: study of the pharmacokinetics and pharmacodynamics of desmopressin oral lyophilisate - route of administration in the pediatric patient population - SAFEPEDRUG
    Medical condition: therapeutic population: monosympthomatic enuresis nocturna diagnostic population: children with a history of a urinary tract infection or suspicion of renal damage who need a renal concentration...
    Disease:
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2013-003418-42 Sponsor Protocol Number: WOE_2013_TUE Start Date*: 2015-03-23
    Sponsor Name:Wörwag Pharma GmbH & Co. KG
    Full Title: Effect of Mg-Orotate administration on cardiocirculatory Performance, the muscular concentration of phosphocreatine and the adaptation of muscle cellular level: A double blind, randomized, placebo-...
    Medical condition: Evaluation of cardiocirculatory performance using clinical and relevant muscle laboratory parameters while taking Mg-Orotate and application of workouts
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2013-002274-41 Sponsor Protocol Number: MCL-metoprolol-CR Start Date*: 2013-07-11
    Sponsor Name:Medisch Centrum Leeuwaarden
    Full Title: The effect of Roux-en-Y gastric bypass on the rate and extent of absorption of metoprolol from a controlled release tablet in female bariatric patient volunteers: a single oral dose study before an...
    Medical condition: Roux-en-Y gastric bypass
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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