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Clinical trials for Continuous infusion

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44336   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    702 result(s) found for: Continuous infusion. Displaying page 1 of 36.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2017-000407-24 Sponsor Protocol Number: DEX-11-01 Start Date*: 2017-02-27
    Sponsor Name:Hospira Inc
    Full Title: A Phase II, Randomized, Open-Label, Single Center, Pharmacokinetic and Pharmacodynamic Study of Dexmedetomidine in Pediatric Subjects Aged 12 months through <24 months
    Medical condition: intubated and mechanically ventilated pediatric subjects that require sedation in an intensive care setting for a minimum of 6 hours but not to exceed 24 hours. Subjects eligible for enrollment a...
    Disease:
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2004-003479-35 Sponsor Protocol Number: 1 Start Date*: 2006-01-02
    Sponsor Name:Internal Medicine IV, Mecdical University of Vienna
    Full Title: PHARMACOKINETICS OF VORICONAZOLE DURING CONTINUOUS VENOVENOUS HEMODIAFILTRATION
    Medical condition: Intensive Care Patients with proven or suspected infection with fungal pathogens requiring parenteral therapy with voricaonzole who are undergoing continuous venovenous hemodiafiltration
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2017-002280-18 Sponsor Protocol Number: FIPRA#3 Start Date*: 2017-09-18
    Sponsor Name:Nordsjællands Hospital Hillerød
    Full Title: Catheter-based peripheral regional anaesthesia after orthopaedic surgery: Comparison of low dose, automated periodic infusions with conventional high dose, continuous infusion, and patient-initiat...
    Medical condition: Postoperative pain, after orthopaedic surgery.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10029173 Nerve block PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2017-000408-71 Sponsor Protocol Number: DEX-11-06 Start Date*: 2017-02-27
    Sponsor Name:Hospira Inc
    Full Title: A Phase II/Ill, Open-Label, Multicenter, Safety, and Efficacy Study of Dexmedetomidine in Preterm Subjects Ages 28 Weeks to < 36 Weeks Gestational Age
    Medical condition: Initially intubated and mechanically ventilated preterm subjects ... 28 weeks through < 36 weeks, gestational age, having a weight of > 1000 g, in an intensive care setting anticipated to require...
    Disease:
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2010-021050-20 Sponsor Protocol Number: AGO/2010/003 Start Date*: 2010-08-25
    Sponsor Name:Ghent University Hospital
    Full Title: Assessment of the optimal dosing of piperacillin-tazobactam in intensive care unit patients: extended versus continuous infusion
    Medical condition: Patients admitted on the intensive care unit (surgical and medical surgery)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2013-002807-32 Sponsor Protocol Number: CONTENT-0001 Start Date*: 2013-10-07
    Sponsor Name:Aarhus University Hospital, Department of Cardiology
    Full Title: Antibiotic treatment for patients with infectious endocarditis: continuous infusion, guided by therapeutic drug monitoring, versus intermittent infusions (the CONTENT study).
    Medical condition: Infectious Endocarditis
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004862 10000667 Acute and subacute infective endocarditis in diseases classified elsewhere LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2021-001019-95 Sponsor Protocol Number: COLIMICINA Start Date*: 2021-05-31
    Sponsor Name:FONDAZIONE POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI IRCCS UNIVERSITA' CATTOLICA DEL SACRO CUORE
    Full Title: Pharmacokinetic/pharmacodynamic aspects of colistin intravenous administration in critically ill patients suffering from hospital infections caused by multi-antibiotic-resistant germs and receiving...
    Medical condition: Critically ill patients suffering from hospital infections caused by multi-antibiotic-resistant germs and receiving continuous renal replacement therapy.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10053840 Bacterial sepsis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-004106-87 Sponsor Protocol Number: CAS CVVH Start Date*: 2007-10-23
    Sponsor Name:Meical University, Dpt. Internal Medicine, Div. of General Internal Medicine
    Full Title: CLINICAL PHARMACOKINETICS OF CASPOFUNGIN IN CRITICALLY ILL PATIENTS DURING CONTINUOUS VENO-VENOUS HEMOFILTRATION
    Medical condition: Plasma concentrations of Caspofungin will be measured in patients requiring treatment with Cancidas (Caspofungin) and continuous veno-venous hemofiltration
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2007-001590-29 Sponsor Protocol Number: 022007 Start Date*: 2007-07-06
    Sponsor Name:Herz-, Thorax- und Gefäßchirurgische Anästhesie und Intensivmedizin
    Full Title: Insulin aspart (NovoRapid®, Novo Nordisk) vs. human insulin (Actrapid®, Novo Nordisk) in intravenous treatment of high blood glucose concentrations in the ICU
    Medical condition: Therapy of hyperglycemia by intravenously applied insulin is going to be investigated. Hyperglycemia is very common in hospitalized, critically ill patients, even if they have not previously had di...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10042216 Stress induced hyperglycemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-005886-15 Sponsor Protocol Number: VASOCONTROL-I Start Date*: 2021-07-21
    Sponsor Name:University Medical Center Groningen
    Full Title: Evaluation of pharmacokinetic and –dynamic characteristics of norepinephrine for the augmentation of arterial blood pressure in healthy volunteers prior to and during general anesthesia
    Medical condition: Bloodpressure during anaesthesia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-002192-25 Sponsor Protocol Number: ABR-62110 Start Date*: 2017-12-06
    Sponsor Name:Center of Expertise in Palliative Care, Maastricht University Medical Centre
    Full Title: Neurotoxic adverse effects of morphine and oxycodone in continuous subcutaneous infusion for treatment of pain in terminal patients with diminished renal function: a Randomized Controlled Trial.
    Medical condition: - The subject is in the terminal phase, i.e. death in the near future is expected by the treating physician; - The subject has a diminished renal function, defined as an eGFR < 50 ml/min/1.73m2; - ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2012-000904-14 Sponsor Protocol Number: MICA_HDF Start Date*: 2012-07-19
    Sponsor Name:Medizinische Universität Wien
    Full Title: PHARMACOKINETICS OF MICAFUNGIN DURING CONTINUOUS VENOVENOUS HEMOFILTRATION
    Medical condition: Suspected or proven candida infection requiring parenteral antifungal therapy
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004862 10042941 Systemic fungal infection NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2011-004702-17 Sponsor Protocol Number: 1804 Start Date*: 2012-01-09
    Sponsor Name:Department of Anaesthesia
    Full Title: Comparison of Ultrasound - Guided Continuous Rectus Sheath Blockade and Continuous Preperitoneal Wound Catheter Infiltration of Local Anaesthetic for Postoperative Analgesia following Laparotomy.
    Medical condition: This study will involve the continuous infusion of local anaesthetic, into either the rectus sheath space, or the preperitoneal space, in order to achieve optimal analgesia for patients who have un...
    Disease: Version SOC Term Classification Code Term Level
    14.0 10042613 - Surgical and medical procedures 10036236 Postoperative pain relief LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-002987-17 Sponsor Protocol Number: LINE_IC_2015 Start Date*: 2016-02-08
    Sponsor Name:Helena Barrasa
    Full Title: Linezolid continuous infusion: optimizing the dosage regimen in critically ill patients through a pharmacokinetic / pharmacodynamic analysis
    Medical condition: Infection
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-020087-38 Sponsor Protocol Number: 2.8022010 Start Date*: 2010-11-25
    Sponsor Name:South Tees Hospitals NHS Foundation Trust
    Full Title: Comparison of the Effects of Intermittent Boluses to Simple Continuous Infusion on Patient Global Perceived Effect in Intrathecal Therapy for Pain.
    Medical condition: Severe, chronic pain in patients who require intrathecal analgesia
    Disease: Version SOC Term Classification Code Term Level
    12.1 10049475 Chronic Pain LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2013-000899-16 Sponsor Protocol Number: UMM022013TG Start Date*: 2013-10-16
    Sponsor Name:Department of Pharmacy Unversitätsmedizin Mainz
    Full Title: Investigation of pharmacokinetics of Linezolid and Meropenem in patients receiving continuous renal replacement therapy
    Medical condition: Sepsis and acute renal failure (ARF) are pathological entities that commonly co-exist in patients admitted to intensive care. Antibiotic dosing in septic patients with ARF can be complicated and ma...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-003403-29 Sponsor Protocol Number: TMP-SMT-CVVH Start Date*: 2014-09-26
    Sponsor Name:Innsbruck Medical University
    Full Title: Pharmacokinetics of trimethoprim-sulfametrole in critically ill patients on continuous veno-venous haemofiltration
    Medical condition: Life-threatening infection treated with trimethoprim-sulfametrole (Rokiprim) in critically ill patients on and off continuous veno-venous haemfiltration
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2006-003737-33 Sponsor Protocol Number: 2006-07 Start Date*: 2006-10-05
    Sponsor Name:Örebro University Hospital
    Full Title: Continuous Intraperitoneal Infusion of Local Anesthetics vs. Patient Controlled Intraperitoneal injection for Postoperative Pain relief following Abdominal Hysterectomy. A randomized, double-blind ...
    Medical condition: Postoperative pain after open abdominal hysterectomy
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-005131-15 Sponsor Protocol Number: 2008/0828 Start Date*: 2008-12-19
    Sponsor Name:CHRU de Lille
    Full Title: ETUDE DE LA PHARMACOCINETIQUE DE L’ASSOCIATION PIPERACILLINE – TAZOBACTAM EN UTILISATION INTRA-VEINEUSE CONTINUE CHEZ L’ENFANT NEUTROPENIQUE FEBRILE .
    Medical condition: febrile episodes in neutropenic patients
    Disease: Version SOC Term Classification Code Term Level
    9.1 10053223 Febrile aplasia LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2005-006172-35 Sponsor Protocol Number: 2005/EMER/18 Start Date*: 2006-07-17
    Sponsor Name:North Hampshire Hospital NHS Trust
    Full Title: A Randomised, Prospective, Double Blinded, Placebo Controlled Trial to Determine the Efficacy of Continuous Infusion Ankle Block Compared to Standard Single Bolus Block in the Management of Postope...
    Medical condition: Any Orthopaedic condition which would require ankle or hind foot surgery under Mr. James Calder at North Hampshire Hospital, Basingstoke.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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