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Clinical trials for Cough reflex

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    11 result(s) found for: Cough reflex. Displaying page 1 of 1.
    EudraCT Number: 2017-003980-36 Sponsor Protocol Number: IIT15419 Start Date*: 2018-01-26
    Sponsor Name:Hull and East Yorkshire Hospitals NHS Trust
    Full Title: A single-Centre, open-label, exploratory study of the effect of 20 mg ambroxol hydrochloride on cough reflex sensitivity in patients with acute cough.
    Medical condition: acute cough assouciated with URTI
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004855 10066522 Acute cough LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2014-005074-11 Sponsor Protocol Number: 14/GAR/002 Start Date*: 2015-04-29
    Sponsor Name:University Hospital South Manchester NHS Foundation Trust
    Full Title: The Role of GABAb receptor mechanisms in cough: Double-blind randomised controlled trial of Lesogaberan in Chronic cough patients with positive and negative symptom association probabilities
    Medical condition: Chronic cough
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004855 10066656 Chronic cough LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2015-002034-47 Sponsor Protocol Number: AF219-014 Start Date*: 2015-10-12
    Sponsor Name:Afferent Pharmaceuticals, Inc.
    Full Title: A Study to Assess the Effect of AF-219 on Cough Reflex Sensitivity in Both Healthy and Chronic Cough Subjects
    Medical condition: Chronic cough
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2013-002728-17 Sponsor Protocol Number: GRC17536-204 Start Date*: 2013-09-24
    Sponsor Name:Glenmark Pharmaceuticals SA
    Full Title: A Phase 2a, Multi-Centre, Randomised, Double-Blind, Parallel Group, Placebo-Controlled Study to Evaluate Efficacy, Safety and Tolerability of Inhaled GRC 17536, Administered for 4 Weeks, in Patient...
    Medical condition: Refractory Chronic Cough.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10038738 - Respiratory, thoracic and mediastinal disorders 10038738 Respiratory, thoracic and mediastinal disorders SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2015-000464-34 Sponsor Protocol Number: AF219-015 Start Date*: 2015-04-29
    Sponsor Name:Afferent Pharmaceuticals, Inc.
    Full Title: A Study to Assess the Effect of AF-219 on Cough Reflex Sensitivity in Both Healthy and Chronic Cough Subjects
    Medical condition: Chronic Cough
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-002165-39 Sponsor Protocol Number: P04887 Start Date*: 2006-11-30
    Sponsor Name:Schering Plough Research Institute, a division of Schering Corporation
    Full Title: Study of the Efficacy and Safety of SCH486757 in Subjects With Chronic Idiopathic Cough
    Medical condition: Chronic Idiopathic Cough
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-002164-26 Sponsor Protocol Number: P04888 Start Date*: 2006-11-10
    Sponsor Name:Schering Plough Research Institute, a division of Schering Corporation
    Full Title: Study of the Efficacy and Safety of SCH619734 in Subjects with Chronic Idiopathic Cough
    Medical condition: Chronic Idiopathic Cough
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2015-001736-38 Sponsor Protocol Number: Academed100215 Start Date*: 2015-08-26
    Sponsor Name:Hull and East Yorkshire Hospitals NHS trust
    Full Title: The utility of feNO in the differential diagnosis of chronic cough: The response to anti-inflammatory therapy with prednisolone and montelukast
    Medical condition: Chronic cough is a common and poorly diagnosed condition. Younger patients tend to receive a diagnosis of asthma, whereas older patients are increasingly identified has having gastroesophageal refl...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2016-004463-39 Sponsor Protocol Number: 221921 Start Date*: 2019-03-06
    Sponsor Name:Sahlgrenska University Hospital, Department of Internal Medicine/Respiratory Medicine and Allergology [...]
    1. Sahlgrenska University Hospital, Department of Internal Medicine/Respiratory Medicine and Allergology
    2. University of Gothenburg
    Full Title: Influence on cough and airway symptoms by oral capsaicin (capscium oleoresin ) – a phase II, randomised, placebo-controlled clinical study in patients with chronic idiopathic cough
    Medical condition: Chronic idiopathic cough
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-004891-20 Sponsor Protocol Number: PNV117270 Start Date*: 2013-09-06
    Sponsor Name:GlaxoSmithKline Research and Development Ltd
    Full Title: A randomised, double-blind (sponsor-unblind), placebo controlled, cross-over study to investigate the efficacy, effect on cough reflex sensitivity, safety, tolerability and pharmacokinetics of inha...
    Medical condition: chronic idiopathic cough
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004855 10066656 Chronic cough LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2018-004744-31 Sponsor Protocol Number: TR12 Start Date*: 2019-06-24
    Sponsor Name:Trevi Therapeutics, Inc.
    Full Title: A Phase 2, Double-Blind, Randomized, Placebo-Controlled, Two-Treatment, Two-Period Crossover Efficacy and Safety Study in Idiopathic Pulmonary Fibrosis With Nalbuphine ER Tablets for the Treatment ...
    Medical condition: Treatment of Cough in Idiopathic Pulmonary Fibrosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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