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Clinical trials for Healthy Elderly Volunteers

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44352   clinical trials with a EudraCT protocol, of which   7379   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    50 result(s) found for: Healthy Elderly Volunteers. Displaying page 1 of 3.
    1  2  3  Next»
    EudraCT Number: 2011-001756-12 Sponsor Protocol Number: UCL-2010-412 Start Date*: 2012-04-27
    Sponsor Name:Cliniques Universitaires Saint Luc - UCL
    Full Title: Surrogate markers evaluation in pre-demented Alzheimer’s disease patients and healthy elderly controls
    Medical condition: Healthy volunteers and Mild Cognitive Impaired patients
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-004305-25 Sponsor Protocol Number: EPU P25 Start Date*: 2006-09-15
    Sponsor Name:Maastricht University
    Full Title: Residual effects of zopiclone 7.5 mg and temazepam 20 mg on cognition and actual driving performance in healthy elderly
    Medical condition: Healthy elderly volunteers
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2022-003248-28 Sponsor Protocol Number: DDD22WATER Start Date*: 2022-12-20
    Sponsor Name:KU Leuven - Drug Delivery and Disposition
    Full Title: The effect of sparkling water on the systemic pharmacokinetics of paracetamol in elderly
    Medical condition: Healthy volunteers, 70+ years of age (administration of an antipyretic, analgesic drug)
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2016-001900-47 Sponsor Protocol Number: 57719 Start Date*: 2017-06-08
    Sponsor Name:Maastricht University Medical Centre +
    Full Title: The effect of lidocaine infusion on ad libitum food intake and satiety in healthy volunteers
    Medical condition: food intake and satiety
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-004129-89 Sponsor Protocol Number: Motor-Neuromod_01, Part I-III Start Date*: 2005-09-19
    Sponsor Name:Universitätsklinikum Münster
    Full Title: Potentiation of procedural motor learning by pharmacological neuromodulation and brain stimulation
    Medical condition: Healthy volunteers Patients in the chronic stage (> 1 year) after stroke
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2014-001545-25 Sponsor Protocol Number: CHDR1409 Start Date*: 2014-07-02
    Sponsor Name:Centre for Human Drug Research
    Full Title: Randomized, double-blind, placebo-controlled, three way crossover, double dummy, single centre study evaluating the effect of haloperidol 2 mg and lorazepam 1 mg on posturography and underlying sys...
    Medical condition: Healthy volunteers (balance disorders)
    Disease: Version SOC Term Classification Code Term Level
    17.0 10029205 - Nervous system disorders 10049848 Balance disorder PT
    17.0 10029205 - Nervous system disorders 10004070 Balance difficulty LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-000438-11 Sponsor Protocol Number: V44P10S Start Date*: 2006-05-05
    Sponsor Name:Chiron Behring GmbH & Co KG
    Full Title: A Phase III, Multicenter, Uncontrolled, Open-label study to evaluate Safety and Immunogenicity of Begrivac, preservative free inactivated Split Influenza Vaccine, using the Strain Composition 2006/...
    Medical condition: no medical condition; healthy volunteers will be recruited into clinical trial for annual approval of Influenza vaccine with new strain composition according to WHO and EMEA recommendation and CPMP...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-001300-37 Sponsor Protocol Number: S201.3.125 Start Date*: 2006-07-11
    Sponsor Name:Solvay Pharmaceuticals B.V.
    Full Title: Immunogenicity and reactogenicity of the trivalent influenza subunit vaccine Influvac® for the season 2006/2007. An open, baseline-controlled study in two groups of healthy subjects: adult subjects...
    Medical condition: Prophylaxis of influenza, especially in those who run an increased risk of associated complications.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2013-002797-42 Sponsor Protocol Number: ANST-2013-Alcohol Start Date*: 2013-09-11
    Sponsor Name:Leiden University Medical Centre
    Full Title: Alcohol and Oxycodone - The influence of the combination of alcohol and an opioid on ventilation in healthy young and elderly volunteers - the 'A&O' study
    Medical condition: Respiratory depression
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-010565-23 Sponsor Protocol Number: V44_13S Start Date*: 2009-05-06
    Sponsor Name:Novartis Vaccines and Diagnostics GmbH & Co. KG
    Full Title: A Phase III, multicenter, uncontrolled, open-label study to evaluate safety and immunogenicity of Begrivac®, preservative free, inactivated split influenza vaccine, using the strain composition 200...
    Medical condition: no medical condition, healthy volunteers will be recruited into the clinical trial for annual approval of influenza vaccine with the new strain composition according WHO and EMEA recommendation and...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-001404-20 Sponsor Protocol Number: V58P1S Start Date*: 2007-05-14
    Sponsor Name:Novartis Vaccines and Diagnostics GmbH & Co. KG
    Full Title: A Phase III, multicenter, uncontrolled, open-label study to evaluate safety and immunogenicity of a single intramuscular dose of a trivalent subunit influenza vaccine produced in mammalian cell cul...
    Medical condition: No medical condition; healthy volunteers will be recruited into clinical trial for annual approval of Influenza vaccine with new strain composition according to WHO and EMEA recommendation and CPMP...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-001403-38 Sponsor Protocol Number: V44P11S Start Date*: 2007-05-10
    Sponsor Name:Novartis Vaccines and Diagnostics GmbH & Co. KG
    Full Title: A Phase III, multicenter, uncontrolled, open-label study to evaluate safety and immunogenicity of Begrivac®, preservative free, inactivated split influenza vaccine, using the strain composition 200...
    Medical condition: No medical condition, healthy volunteers will be recruited into clinical trial for annual approval of influenza vaccine with the new strain composition according WHO and EMEA recommendation and CPM...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-000887-18 Sponsor Protocol Number: V44P12S Start Date*: 2008-05-13
    Sponsor Name:Novartis Vaccines and Diagnostics GmbH & Co KG
    Full Title: A Phase III, multicenter, uncontrolled, open-label study to evaluate safety and immunogenicity of Begrivac®, preservative free, inactivated split influenza vaccine, using the strain composition 200...
    Medical condition: No medical condition, healthy volunteers will be recruited into clinical trial for annual approval of influenza vaccine with the new strain composition accordng WHO and EMEA recommendation and CPMP...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-014810-87 Sponsor Protocol Number: CL2-NEURO-005 Start Date*: 2010-07-22
    Sponsor Name:INSTITUT DE RECHERCHES INTERNATIONALES SERVIER
    Full Title: Effect of Memantine 20 mg (Ebixa) and Donepezil 5 mg (Aricept) on motor cortex plasticity induced by paired associative stimulation using transcranial magnetic stimulation (TMS) in patients sufferi...
    Medical condition: - Patients suffering from Mild Cognitive Impairment (memory problems, objective memory disorder, absence of other cognitive disorders or repercussions on daily life, normal general cognitive functi...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-017052-27 Sponsor Protocol Number: 200910H1N1MHH Start Date*: 2010-02-09
    Sponsor Name:Medizinische Hochschule Hannover
    Full Title: A Phase II Study to Evaluate the Immunogenicity, Safety and Tolerability of a H1N1 Influenza Vaccine in Immunocompromised Adults Who Have Undergone Solid Organ Transplantation or Bone Marrow Transp...
    Medical condition: Vaccination for H1N1sw of immunocompromised adults who have undergone solid organ or bone marrow transplantation and of healthy adults
    Disease: Version SOC Term Classification Code Term Level
    12.1 10022000 Influenza LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2004-004232-31 Sponsor Protocol Number: A6061025 Start Date*: 2004-11-29
    Sponsor Name:Pfizer Ltd
    Full Title: A double-blind (third party open), placebo-controlled, parallel group, multiple dose study to investigate the safety, toleration and pharmacokinetics of [S,S]-Reboxetine in young and elderly health...
    Medical condition: Postherpetic Neuralgia
    Disease: Version SOC Term Classification Code Term Level
    10036376 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-018371-18 Sponsor Protocol Number: V44_14S Start Date*: 2010-04-22
    Sponsor Name:Novartis Vaccines and Diagnostics GmbH
    Full Title: A Phase III, multicenter, uncontrolled, open-label study to evaluate safety and immunogenicity of Begrivac®, preservative free, inactivated split influenza vaccine, using the strain composition 201...
    Medical condition: no medical condition, healthy volunteers will be recruited into the clinical trial for annual approval of influenza vaccine with the new strain composition according WHO and EMEA recommendation and...
    Disease: Version SOC Term Classification Code Term Level
    12.1 10022000 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2012-000085-38 Sponsor Protocol Number: V70_39S Start Date*: 2012-03-08
    Sponsor Name:NOVARTIS VACCINES AND DIAGNOSTICS S.R.L.
    Full Title: A Phase II, Open Label, Uncontrolled, Multi Center Study to Evaluate Safety and Immunogenicity of FLUAD Surface Antigen, Inactivated, Adjuvanted with MF59C.1 Influenza Vaccine, Formulation 2012-201...
    Medical condition: Clinical Trial on healthy volunteers (Active immunisation against influenza in the elderly (65 years of age and over), especially for those with an increased risk of associated complications (i.e. ...
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10022000 Influenza PT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended) BE (Completed)
    Trial results: View results
    EudraCT Number: 2010-024613-31 Sponsor Protocol Number: V58_25S Start Date*: 2011-06-17
    Sponsor Name:Novartis Vaccines and Diagnostics GmbH
    Full Title: A Phase III Open Label, Uncontrolled, Multi Center Study to Evaluate Safety and Immunogenicity of a Surface, Antigen, Inactivated, Influenza Vaccine Produced in Mammalian Cell Culture (Optaflu®),...
    Medical condition: no medical condition, healthy volunteers will be recruited into the clincial trial for annual approval of influenza vaccine with the new strain composition according WHO and EMEA recommendation and...
    Disease: Version SOC Term Classification Code Term Level
    13.1 10021881 - Infections and infestations 10022000 Influenza PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2011-006277-25 Sponsor Protocol Number: V58_32S Start Date*: 2012-06-27
    Sponsor Name:Novartis Vaccines and Diagnostics GmbH
    Full Title: A Phase III Open Label, Uncontrolled, Multi Center Study to Evaluate Safety and Immunogenicity of a Surface, Antigen, Inactivated, Influenza Vaccine Produced in Mammalian Cell Culture (Optaflu®),...
    Medical condition: no medical condition, healthy volunteers will be recruited into the clincial trial for annual approval of influenza vaccine with the new strain composition according WHO and EMEA recommendation and...
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10022000 Influenza PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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