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Clinical trials for Heart disease

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    2,671 result(s) found for: Heart disease. Displaying page 1 of 134.
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    EudraCT Number: 2017-002712-14 Sponsor Protocol Number: AK2017-4 Start Date*: 2017-11-21
    Sponsor Name:Rigshospitalet, Department of Physiology, Nuclear Medicine and PET
    Full Title: Phase II: 68Ga-NODAGA-E[c(RGDyK)]2 Angiogenese PET for imaging angiogenesis in ischaemic heart disease
    Medical condition: Ischaemic heart disease
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10023024 Ischaemic heart disease LLT
    20.0 10007541 - Cardiac disorders 10008937 Chronic ischemic heart disease, unspecified LLT
    20.0 10007541 - Cardiac disorders 10055218 Ischemic heart disease LLT
    20.0 10007541 - Cardiac disorders 10008936 Chronic ischaemic heart disease, unspecified LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2013-000887-27 Sponsor Protocol Number: 1.0 Start Date*: 2013-05-23
    Sponsor Name:Medizinische Universität Wien
    Full Title: Pilot Trial: The effects of intravenous heme arginate on HO-1 expression and oxidative stress in the human heart
    Medical condition: ischemia reperfusion injury
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004849 10055224 Cardiac ischemia LLT
    14.1 100000004849 10023031 Ischemia coronary artery origin LLT
    14.1 100000004849 10023033 Ischemia myocardial LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2008-001850-42 Sponsor Protocol Number: MSC3 Start Date*: 2008-06-16
    Sponsor Name:The Heart Centre, Rigshospitalet
    Full Title: Autolog mesenkymal stromal cellebehandling af patienter med hjertesvigt.
    Medical condition: Congestive heart failure
    Disease: Version SOC Term Classification Code Term Level
    9.1 10010684 Congestive heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2020-004178-23 Sponsor Protocol Number: T39/2021 Start Date*: 2021-04-14
    Sponsor Name:Turku University Hospital
    Full Title: Ultrasound Guided Repeated Bilateral Transversus Thoracis Muscle Plane Block (TTP) via catheter and postoperative pain in Cardiac Surgery
    Medical condition: cardiac disease necessitating surgery with sternotomy
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10046972 Valvular heart disease NOS LLT
    20.0 100000004849 10055218 Ischemic heart disease LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2007-005789-11 Sponsor Protocol Number: atorv02 Start Date*: 2008-03-11
    Sponsor Name:RUNMC
    Full Title: Does atorvastatin have an acute and prolonged inhibitory effect on ischemia-reperfusion injury in humans in-vivo?
    Medical condition: ischemia-reperfusion injury
    Disease: Version SOC Term Classification Code Term Level
    9.1 10023033 Ischemia myocardial LLT
    Population Age: Adults Gender: Male
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2009-017625-20 Sponsor Protocol Number: NAROSYD Start Date*: 2010-06-22
    Sponsor Name:Pawel Florkiewicz
    Full Title: Continuous ropivacaine infusion in treatment of postoperative pain in cardiac surgery.
    Medical condition: Research is to verify whether continuous infusion of ropivacaine reduces post-operative analgesic requirement after cardiac surgery.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10019316 Heart valve disorders LLT
    12.1 10052895 Coronary artery insufficiency LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-005359-18 Sponsor Protocol Number: RIVENDEL Start Date*: 2013-01-22
    Sponsor Name:UNIVERSITA' CAMPUS BIOMEDICO
    Full Title: Heart Rate reduction by IVabradine for improvement of ENDothELial function in patients with coronary artery disease: the RIVENDEL study
    Medical condition: PATIENTS WITH CAD AFTER CORONARY ANGIOPLASTY
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10007541 Cardiac disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-001443-22 Sponsor Protocol Number: rivascolarizzazione miocardica Start Date*: 2006-09-21
    Sponsor Name:AZIENDA OSPEDALIERA OSPEDALE POLICLINICO CONSORZIALE
    Full Title: Effects of the administrartion of two different dosages of eparin on activation of coagulation pathway and of fibrinolisis and on platenet function in patients with myocardial revascolarization ope...
    Medical condition: Patients who are suitable candidates for off-pump myocardial revascularization
    Disease: Version SOC Term Classification Code Term Level
    9.1 10007541 Cardiac disorders SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-007287-42 Sponsor Protocol Number: IVA-TCMD Start Date*: 2009-04-17
    Sponsor Name:AZIENDA OSPEDALIERA DI PARMA
    Full Title: Ivabradine in multislice CT: comparison with metoprolol in the reduction of motion artefacts and in the improvement of diagnostic care.
    Medical condition: patients with coronary arteries desease, who need Tc multislice for diagnostic reasons
    Disease: Version SOC Term Classification Code Term Level
    9.1 10007541 SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2022-002688-31 Sponsor Protocol Number: ICOR-2022-04-LEVOMEMS Start Date*: 2023-01-25
    Sponsor Name:Germans Trias i Pujol Health Research Institute
    Full Title: LEVO-MEMS: COMPARISION OF THE HAEMODINAMIC PROFILE OF DOBUTAMIN AND LEVOSIMENDAN IN THE CURRENT THERAPEUTICAL CONTEXT
    Medical condition: Heart failure patients with depressed left ventricular ejection fraction
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10019279 Heart failure LLT
    20.0 100000004849 10010684 Congestive heart failure LLT
    20.0 100000004849 10019284 Heart failure, congestive LLT
    20.0 100000004849 10024106 Left heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-016958-41 Sponsor Protocol Number: FO002 Start Date*: 2010-02-28
    Sponsor Name:AZIENDA OSPEDALIERA OSPEDALE NIGUARDA CA` GRANDA (A.O. DI RILIEVO NAZIONALE)
    Full Title: Early LEvosimendan Vs usual care in Advanced chronic hearT failurE
    Medical condition: Advanced chronic heart failure
    Disease: Version SOC Term Classification Code Term Level
    9.1 10007541 SOC
    9.1 10007541 SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-002149-20 Sponsor Protocol Number: RE-01-DIAGN.INTERV.CARD. - CIN Start Date*: 2007-04-18
    Sponsor Name:AZIENDA OSPEDALIERA ARCISPEDALE S. MARIA NUOVA
    Full Title: Contrast indiced nephropaty (CIN) in patients undergoing primary angioplasty for acute myocardial infarction. Randomized trial on the effects of hydration with saline or sodium bicarbonate.
    Medical condition: AMI
    Disease: Version SOC Term Classification Code Term Level
    6.1 10007541 SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-001481-32 Sponsor Protocol Number: Effetto anti-infiammatorio insulin Start Date*: 2006-09-21
    Sponsor Name:AZIENDA OSPEDALIERA OSPEDALE POLICLINICO CONSORZIALE
    Full Title: Evaluation of the anti-inflammatory effect of continous insulin infusion in non-diabetic patients undergoing cardia surgery
    Medical condition: Patients candidate to cardiac surgery
    Disease: Version SOC Term Classification Code Term Level
    9.1 10007541 Cardiac disorders SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-022952-22 Sponsor Protocol Number: GIU-LU-RO Start Date*: 2010-10-22
    Sponsor Name:AZIENDA OSPEDALIERA MAGGIORE DELLA CARITA` DI NOVARA
    Full Title: N-Acetytilcysteine Versus placebo for the prevention of Acute Reduction in Renal function after primary Angioplasty (NoVARA)
    Medical condition: patient with ST elevation myocardial acute infarction
    Disease: Version SOC Term Classification Code Term Level
    9.1 10007541 SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-002553-50 Sponsor Protocol Number: 29/2005/O- CP18549 Start Date*: 2005-05-24
    Sponsor Name:AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI
    Full Title: non disponibile
    Medical condition: non disponibile
    Disease: Version SOC Term Classification Code Term Level
    6.1 10007541 SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-004337-33 Sponsor Protocol Number: APAF/01 Start Date*: 2004-11-12
    Sponsor Name:OSPEDALE S. RAFFAELE
    Full Title: RANDOMIZED COMPARISON OF CIRCUMFERENTIAL PULMONARY VEIN ABLATION VERSUS ANTIARRHYTHMIC THERAPY FOR CURING PATIENTS WITH PAROXYSMAL ATRIAL FIBRILLATION. (APAF STUDY)
    Medical condition: APPLICATION OF CIRCUMFERENTIAL PULMONARY VEIN ABLATION IN THE TREATMENT OF PAROXYSMAL ATRIAL FIBRILLATION
    Disease: Version SOC Term Classification Code Term Level
    6.1 10007541 SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2009-013066-31 Sponsor Protocol Number: HSR-LEVO Start Date*: 2009-07-31
    Sponsor Name:FONDAZIONE CENTRO S. RAFFAELE DEL MONTE TABOR
    Full Title: “Levosimendan to reduce mortality in high risk cardiac surgery patients. A multicentre randomized controlled trial.”
    Medical condition: high risk cardiac surgery affected by low cardiac output syndrome (LCOs)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10007541 SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-020117-87 Sponsor Protocol Number: REACT-ON Terapia Start Date*: 2010-05-03
    Sponsor Name:FONDAZIONE SALVATORE MAUGERI - CLINICA DEL LAVORO E DELLA RIABILITAZIONE
    Full Title: REACT ON (REscuing ACTivity Of Na-channels) STUDY Study and correction of abnormalities of nonsense mutations in Brugada Syndrome.
    Medical condition: Brugada syndrome
    Disease: Version SOC Term Classification Code Term Level
    9.1 10007541 SOC
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2010-022389-28 Sponsor Protocol Number: 25862 Start Date*: 2010-11-12
    Sponsor Name:Lars Søndergaard
    Full Title: Treatment with Endothelinantagonist to tcpc patients; a multicenter, randomized, Prospective study measuring maximal O2 uptake in ergometer bicycle test. [TEMPO-study].
    Medical condition: Patients with a univentricular heart, who have recieved paliating surgery in the form of TCPC operation
    Disease: Version SOC Term Classification Code Term Level
    14.1 10010331 - Congenital, familial and genetic disorders 10021076 Hypoplastic left heart syndrome PT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-000561-28 Sponsor Protocol Number: SOSP- CLOP Start Date*: 2008-05-08
    Sponsor Name:AZIENDA OSPEDALIERA OSPEDALE NIGUARDA CA` GRANDA (A.O. DI RILIEVO NAZIONALE)
    Full Title: Urgent surgery in patients with a recently implanted coronary drug-eluting stent: a phase II study of bridging antiplatelet therapy with tirofiban during temporary withdrawal of clopidogrel.
    Medical condition: prevention of cardiac ischemic events in patients undergoing major or ocular surgery
    Disease: Version SOC Term Classification Code Term Level
    9.1 10007541 SOC
    9.1 10007541 SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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