Flag of the European Union EU Clinical Trials Register Help

Clinical trials for Heart surgery

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44339   clinical trials with a EudraCT protocol, of which   7369   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
    Advanced Search: Search tools
     
    628 result(s) found for: Heart surgery. Displaying page 1 of 32.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2015-004485-28 Sponsor Protocol Number: 38RC15.214 Start Date*: 2016-01-18
    Sponsor Name:Centre Hospitalier Universitaire de Grenoble
    Full Title:
    Medical condition: Patients should be operated for cardiac surgery with cardiac bypass and in sinus rhythm, and for which the fact of the existence of impaired left ventricular function or the heaviness of the surgic...
    Disease: Version SOC Term Classification Code Term Level
    18.1 10042613 - Surgical and medical procedures 10061026 Cardiac operation PT
    Population Age: Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2020-004178-23 Sponsor Protocol Number: T39/2021 Start Date*: 2021-04-14
    Sponsor Name:Turku University Hospital
    Full Title: Ultrasound Guided Repeated Bilateral Transversus Thoracis Muscle Plane Block (TTP) via catheter and postoperative pain in Cardiac Surgery
    Medical condition: cardiac disease necessitating surgery with sternotomy
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10046972 Valvular heart disease NOS LLT
    20.0 100000004849 10055218 Ischemic heart disease LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2007-001481-32 Sponsor Protocol Number: Effetto anti-infiammatorio insulin Start Date*: 2006-09-21
    Sponsor Name:AZIENDA OSPEDALIERA OSPEDALE POLICLINICO CONSORZIALE
    Full Title: Evaluation of the anti-inflammatory effect of continous insulin infusion in non-diabetic patients undergoing cardia surgery
    Medical condition: Patients candidate to cardiac surgery
    Disease: Version SOC Term Classification Code Term Level
    9.1 10007541 Cardiac disorders SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-013066-31 Sponsor Protocol Number: HSR-LEVO Start Date*: 2009-07-31
    Sponsor Name:FONDAZIONE CENTRO S. RAFFAELE DEL MONTE TABOR
    Full Title: “Levosimendan to reduce mortality in high risk cardiac surgery patients. A multicentre randomized controlled trial.”
    Medical condition: high risk cardiac surgery affected by low cardiac output syndrome (LCOs)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10007541 SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-000887-27 Sponsor Protocol Number: 1.0 Start Date*: 2013-05-23
    Sponsor Name:Medizinische Universität Wien
    Full Title: Pilot Trial: The effects of intravenous heme arginate on HO-1 expression and oxidative stress in the human heart
    Medical condition: ischemia reperfusion injury
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004849 10055224 Cardiac ischemia LLT
    14.1 100000004849 10023031 Ischemia coronary artery origin LLT
    14.1 100000004849 10023033 Ischemia myocardial LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2008-000561-28 Sponsor Protocol Number: SOSP- CLOP Start Date*: 2008-05-08
    Sponsor Name:AZIENDA OSPEDALIERA OSPEDALE NIGUARDA CA` GRANDA (A.O. DI RILIEVO NAZIONALE)
    Full Title: Urgent surgery in patients with a recently implanted coronary drug-eluting stent: a phase II study of bridging antiplatelet therapy with tirofiban during temporary withdrawal of clopidogrel.
    Medical condition: prevention of cardiac ischemic events in patients undergoing major or ocular surgery
    Disease: Version SOC Term Classification Code Term Level
    9.1 10007541 SOC
    9.1 10007541 SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2004-000100-40 Sponsor Protocol Number: f7card-1610 Start Date*: 2004-08-18
    Sponsor Name:Novo Nordisk A/S
    Full Title: Estudio multicentrico. aleatorizado, doble ciego, controlado con placebo y con escalada de dosis sobre la seguridad y la eficacia del factor VII recombinante activado (rFVIIa/NovoSeven) en el trata...
    Medical condition: Enfermedad de corazon/cirugia cardiaca.
    Disease: Version SOC Term Classification Code Term Level
    10061026
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed) SE (Prematurely Ended) GB (Prematurely Ended) IT (Prematurely Ended) DK (Completed)
    Trial results: View results
    EudraCT Number: 2012-003396-20 Sponsor Protocol Number: MMUH-Conway01 Start Date*: 2012-11-26
    Sponsor Name:Cardiothoracic Surgery, Mater Misericordiae University Hospital
    Full Title: Is the optimal dose of preoperative statin associated with decreased end organ injury and better clinical outcome post cardiopulmonary bypass?
    Medical condition: Patient listed for open heart surgery involving cardiopulmonary bypass.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-004877-38 Sponsor Protocol Number: PREVENT-MINS Start Date*: 2021-06-18
    Sponsor Name:Uniwersytet Jagielloński - Collegium Medicum
    Full Title: Ivabradine for PREVENTion of Myocardial Injury after Noncardiac Surgery (MINS) - PREVENT-MINS Trial
    Medical condition: Myocardial Injury after Noncardiac Surgery
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10028601 Myocardial ischemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2009-017625-20 Sponsor Protocol Number: NAROSYD Start Date*: 2010-06-22
    Sponsor Name:Pawel Florkiewicz
    Full Title: Continuous ropivacaine infusion in treatment of postoperative pain in cardiac surgery.
    Medical condition: Research is to verify whether continuous infusion of ropivacaine reduces post-operative analgesic requirement after cardiac surgery.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10019316 Heart valve disorders LLT
    12.1 10052895 Coronary artery insufficiency LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-022389-28 Sponsor Protocol Number: 25862 Start Date*: 2010-11-12
    Sponsor Name:Lars Søndergaard
    Full Title: Treatment with Endothelinantagonist to tcpc patients; a multicenter, randomized, Prospective study measuring maximal O2 uptake in ergometer bicycle test. [TEMPO-study].
    Medical condition: Patients with a univentricular heart, who have recieved paliating surgery in the form of TCPC operation
    Disease: Version SOC Term Classification Code Term Level
    14.1 10010331 - Congenital, familial and genetic disorders 10021076 Hypoplastic left heart syndrome PT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-004343-80 Sponsor Protocol Number: 545.12 Start Date*: 2012-09-20
    Sponsor Name:OSPEDALE PEDIATRICO BAMBINO GESU' DI ROMA
    Full Title: STUDY PHASE III, RANDOMIZED, DOUBLE-BLIND CONTROLLED TO EVALUATE THE EFFECTIVENESS OF FUROSEMIDE IN CONTINUOUS INFUSION VS ethacrynic acid IN CONTINUOUS INFUSION IN CHILDREN SUBJECT TO A heart sur...
    Medical condition: ALL CHILDREN AGE 'LESS THAN 10 YEARS OF AGE' WITH CONGENITAL HEART PROCEDURE SUBJECT TO cardiac surgery in whom the diuretic ARE GIVEN IN ACCORDANCE WITH THE FOLLOWING CONTINUOUS INFUSION PROTOCOL ...
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10007541 Cardiac disorders SOC
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-002803-17 Sponsor Protocol Number: 2340 Start Date*: 2008-09-04
    Sponsor Name:Med. Univ. Wien, Klinik Innere Medizin I, Intensivstation
    Full Title: PROPHYLACTIC, DOUBLE BLIND, PLACEBO CONTROLLED RANDOMIZED USE OF HOMEOPATHY FOR PREVENTION OF ATRIAL FIBRILLATION IN PATIENTS WITH AORTOCORONARY BYPASS OR HEART VALVE SURGERY WITH HEART-LUNG MACHINE
    Medical condition: Patients suffering from atrial fibrillation following heart surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-000818-78 Sponsor Protocol Number: 7-010-MR Start Date*: 2008-09-25
    Sponsor Name:POLICLINICO SAN DONATO IRCSS
    Full Title: Efficacy of fenoldopam mesilate in controlling splanchnic ischemia during cardiopulmonary bypass
    Medical condition: Patients to be submitted to cardiac surgery with expected prolonged CPB time
    Disease: Version SOC Term Classification Code Term Level
    9.1 10048935 Open heart surgery LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2010-021844-17 Sponsor Protocol Number: 33197 Start Date*: 2010-12-17
    Sponsor Name:Erasmus Medical Centre
    Full Title: Perioperative esmolol infusion for haemodynamic stability during major vascular surgery.
    Medical condition: cardiac complications during and after vascular surgery
    Disease: Version SOC Term Classification Code Term Level
    12.1 10028601 Myocardial ischemia LLT
    Population Age: Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-001752-43 Sponsor Protocol Number: SEVO-AIFA-FARM6H73Z9 Start Date*: 2008-07-17
    Sponsor Name:OSPEDALE S. RAFFAELE
    Full Title: CARDIAC PROTECTION WITH SEVOFLURANE IN PATIENTS WITH HIGH RISK UNDERGOING HEART SURGERY. RANDOMIZED, CONTROLLED STUDY.
    Medical condition: adult patients affected by cardiac valve and heart patology undergoing elective surgery
    Disease: Version SOC Term Classification Code Term Level
    9.1 10061406 Cardiac valve disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2007-000390-31 Sponsor Protocol Number: HyperHAES-PÄD-CARDIO-02 Start Date*: 2007-10-30
    Sponsor Name:Universitätsklinikum Erlangen
    Full Title: Application of hypertonic hyperoncotic solutions for improvement of cardiac output after open heart surgery in children - monocentric, randomised, placebo controlled, double-blind clinical trial (p...
    Medical condition: Children after open-heart surgery for congenital cardiac disease
    Disease: Version SOC Term Classification Code Term Level
    9.1 10019273 Heart disease congenital LLT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-021263-33 Sponsor Protocol Number: 3001101 Start Date*: 2011-05-24
    Sponsor Name:Sykehuset i Vestfold HF
    Full Title: PERIOPERATIVE LEVOSIMENDAN INFUSION IN PATIENTS WITH HEART FAILURE UNDERGOING NON-CARDIAC SURGERY: A PROSPECTIVE, RANDOMISED, PLACEBO-CONTROLLED, DOUBLE-BLIND, MULTICENTER STUDY
    Medical condition: Patients with serious cardiac failure scheduled for non-cardiac surgery
    Disease: Version SOC Term Classification Code Term Level
    14.1 10022117 - Injury, poisoning and procedural complications 10006387 Broken hip LLT
    14.1 10007541 - Cardiac disorders 10007559 Cardiac failure congestive PT
    14.1 10007541 - Cardiac disorders 10007554 Cardiac failure PT
    14.1 10007541 - Cardiac disorders 10066498 Cardiac failure chronic aggravated LLT
    14.1 10007541 - Cardiac disorders 10007558 Cardiac failure chronic PT
    14.1 10007541 - Cardiac disorders 10024102 Left cardiac failure LLT
    14.1 10007541 - Cardiac disorders 10007561 Cardiac failure left LLT
    14.1 10007541 - Cardiac disorders 10007555 Cardiac failure (NOS) LLT
    14.1 10007541 - Cardiac disorders 10007564 Cardiac failure, congestive LLT
    14.1 10007541 - Cardiac disorders 10007562 Cardiac failure NOS LLT
    14.1 10022117 - Injury, poisoning and procedural complications 10020100 Hip fracture PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-015013-46 Sponsor Protocol Number: AnaesthesiaResearch024 Start Date*: 2009-12-14
    Sponsor Name:Alfred Health
    Full Title: The ATACAS Trial: Aspirin and Tranexamic Acid for Coronary Artery Surgery Trial
    Medical condition: Coronary Artery Bypass Grafting
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-005757-30 Sponsor Protocol Number: MIRACL IN CABG Start Date*: 2007-07-30
    Sponsor Name:AZIENDA OSPEDALIERO UNIVERSITARIA OSPEDALI RIUNITI UMBERTO I - G.M.LANCISI - G.SALESI
    Full Title: MIRACL IN CABG - Statins in cardiac surgery. Effect of doses on inflammatory response and early results
    Medical condition: Pts with coronary disease undergoing coronary artery bypass graft surgery.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10028600 Myocardial ischaemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    Download Options:
    Number of Trials to download:
    Download Content:
    Download Format:
    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    Query did not match any studies.
    For support, Contact us.
    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

    European Medicines Agency © 1995-Fri May 30 05:36:19 CEST 2025 | Domenico Scarlattilaan 6, 1083 HS Amsterdam, The Netherlands
    EMA HMA