Flag of the European Union EU Clinical Trials Register Help

Clinical trials for Homocysteine

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   43881   clinical trials with a EudraCT protocol, of which   7295   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
    Advanced Search: Search tools
     
    31 result(s) found for: Homocysteine. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2015-004311-20 Sponsor Protocol Number: GU20151201 Start Date*: 2016-03-30
    Sponsor Name:Gothenburg University
    Full Title: Effect of vitamin B substitution on plasma NFL and neurocognitive performance in HIV-infected individuals with increased plasma homocysteine
    Medical condition: HIV
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-002306-29 Sponsor Protocol Number: RLH 2786 Start Date*: 2004-12-21
    Sponsor Name:Royal Liverpool and Broadgreen University Hospitals NHS Trust
    Full Title: Psoriasis, Folic Acid Supplementation and Plasma Homocysteine Levels
    Medical condition: Psoriasis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2005-000551-15 Sponsor Protocol Number: MTXa54 Start Date*: 2005-09-05
    Sponsor Name:University of Dundee
    Full Title: Effect of folic acid supplementation and allopurinol on endothelial function in patients with rheumatoid arthritis treated with methotrexate
    Medical condition: Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory polyarthritis associated with excess cardiovascular (CV) mortality. Hyperhomocysteinaemia is recognized as an independent CV risk fact...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2018-003619-23 Sponsor Protocol Number: 6630-4200-42 Start Date*: 2019-11-29
    Sponsor Name:MEDICE Arzneimittel Pütter GmbH & Co. KG
    Full Title: EFFICACY AND SAFETY OF A PARENTERALLY ADMINISTERED FIXED VITAMIN COMBINATION (VITAMIN B6, B12 AND FOLIC ACID) ON VITAMIN B12 STATUS AND METHYLATION CAPACITY IN COBALAMIN DEFICIENCY COMPARED TO ORAL...
    Medical condition: vitamin B12 deficiency
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-005666-37 Sponsor Protocol Number: PrefoDIP Start Date*: 2012-10-17
    Sponsor Name:ZAMBON ITALIA
    Full Title: Evaluation of the effect exerted by 5-methyltetrahydrofolate (5-MTHF) and folic acid in postmenopausal women
    Medical condition: The study evaluates the effects of different forms of folates on cardiovascular risk factors in postmenopausal patients
    Disease: Version SOC Term Classification Code Term Level
    14.1 10041244 - Social circumstances 10051775 Postmenopause PT
    Population Age: Adults Gender: Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-005643-26 Sponsor Protocol Number: PrefoCir2 Start Date*: 2012-03-15
    Sponsor Name:ZAMBON ITALIA
    Full Title: Cross-over pharmacokinetic study and pharmacodynamics of 2 different folate (5-MTHF and folic acid) in patients with liver cirrhosis with viral etiology. A randomized, open-label trial.
    Medical condition: In all cases of folate deficiency due to increased demand, poor absorption, inadequate dietary intake and reduced utilization of the vitamin in patients with viral liver cirrhosis.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10047457 Viral hepatitis C LLT
    14.1 10021881 - Infections and infestations 10047450 Viral hepatitis B LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-005698-31 Sponsor Protocol Number: 4/2005 Start Date*: 2006-09-12
    Sponsor Name:National Medical Center (Országos Gyógyintézeti Központ)
    Full Title: Efficacy of fenofibrate treatment on the insulin sensitivity and pancreas ß-cell function in obese patients with hypertriglyceridemia.
    Medical condition: Patients non-diabetic, obese with hypertriglyceridemia (previously untreated with fibrate).
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: HU (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-000451-34 Sponsor Protocol Number: FARM5XWMZ4 Start Date*: 2007-10-01
    Sponsor Name:AZIENDA OSPEDALIERA UNIVERSITARIA DELLA SECONDA UNIVERSITA` DEGLI STUDI DI NAPOLI
    Full Title: Therapy of hyperhomocysteinemia in hemodialysis patients:effects of acetylcysteine and folates.
    Medical condition: Hyperhomocysteinemia in hemodialysis.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10038359 SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-004399-35 Sponsor Protocol Number: Pfi-RW-2005-01 Start Date*: 2005-01-18
    Sponsor Name:North Glasgow Trust
    Full Title: The effects of eplerenone on left ventricular remodelling post-acute myocardial infarction: a double-blind placebo-controlled cardiac MR-based study.
    Medical condition: Post-myocardial infarction left ventricular dysfunction, in the absence of heart failure - clinical (i.e. Killip III or IV) or radiological - nor established diabetes mellitus.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-001578-28 Sponsor Protocol Number: MeES/05/Neb-EnD/001 Start Date*: 2006-01-17
    Sponsor Name:Berlin-Chemie AG Menarini Group
    Full Title: Comparison the effects of Nebivolol versus Metoprolol succinate on endothelial function and large artery stiffness. A parallel group, randomized, double-blind, active control phase IV clinical tria...
    Medical condition: Atherosclerosis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: EE (Completed)
    Trial results: View results
    EudraCT Number: 2013-000356-18 Sponsor Protocol Number: 25051974 Start Date*: 2023-12-21
    Sponsor Name:Stichting Apotheek der Haarlemse Ziekenhuizen
    Full Title: Effect of repeated intranasal cobalamin administration on cobalamin deficiency in elderly
    Medical condition: Cobalamin (vitamin B12) deficiency
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-005773-35 Sponsor Protocol Number: 2008-005773-35 Start Date*: Information not available in EudraCT
    Sponsor Name:AZIENDA OSPEDALIERA DI PADOVA
    Full Title: AUTOLOUGUS STEM CELLS TRANSPLANTATION AFTER LINFOCYTE DEPLETION AS A NEW THERAPY FOR THE AGGRESSIVE AND DRUG RESISTANT FORMS OF MULTIPLE SLEROSIS IN THE ADULTS AND CHILDREN.
    Medical condition: MULTIPLE SCLEROSIS
    Disease: Version SOC Term Classification Code Term Level
    15.1 100000004852 10028053 MS LLT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-022363-35 Sponsor Protocol Number: mnp_001 Start Date*: 2011-02-18
    Sponsor Name:Clinical research lab for neurodegeneration, Dept. of Neurology, St. Josef-Hospital, Ruhr-University
    Full Title: Impact of Levodopa vs. Rotigotine on stress hormones and NGF in patients with Parkinson's Disease: A randomised, placebo-controlled double-blind trial.
    Medical condition: Parkinson's disease
    Disease: Version SOC Term Classification Code Term Level
    12.1 10013113 Disease Parkinson's LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-000490-37 Sponsor Protocol Number: PR001 Start Date*: 2008-02-26
    Sponsor Name:OSPEDALE S. RAFFAELE
    Full Title: Pharmacological treatment with memantine of oscilloscopy in patients suffering from multiple sclerosis: randomized,double blind placebo controlled study.
    Medical condition: multiple sclerosis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10028053 MS LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2019-004791-19 Sponsor Protocol Number: CACN00177-100D Start Date*: 2020-05-11
    Sponsor Name:Aeglea Biotherapeutics, Inc.
    Full Title: A Phase 1/2 Multiple Ascending-Dose Study in Subjects With Homocystinuria Due to Cystathionine β-Synthase (CBS) Deficiency to Investigate the Safety, Pharmacokinetics, and Pharmacodynamics of ACN00177
    Medical condition: Homocystinuria Due to Cystathionine β-Synthase (CBS) Deficiency
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10020365 Homocystinuria PT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2005-003583-31 Sponsor Protocol Number: BCBe/05/Neb-Pao/088 Start Date*: 2006-04-12
    Sponsor Name:Berlin-Chemie AG
    Full Title: NEBIVOLOL OR METOPROLOL IN ARTERIAL OCCLUSIVE DISEASE A DOUBLE-BLIND, RANDOMISED CLINICAL Deutscher Titel: Nebivolol im Vergleich zu Metoprolol bei peripherer arterieller Verschlusskrankheit Eine ...
    Medical condition: Intermittent claudication (peripheral arterial disease) Fontaine’s stage II Deutsch: Periphere arterielle Verschlusskrankheit, Fontaine Staidum II
    Disease: Version SOC Term Classification Code Term Level
    8.0 10062585 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2019-001061-32 Sponsor Protocol Number: mRNA-3704-P101 Start Date*: 2019-10-25
    Sponsor Name:ModernaTX, Inc.
    Full Title: A Global, Phase 1/2, Open Label, Dose Escalation Study to Evaluate the Safety, Pharmacodynamics, and Pharmacokinetics of mRNA-3704 in Patients with Isolated Methylmalonic Acidemia Due to Methylmalo...
    Medical condition: Isolated Methylmalonic Acidemia Due to Methylmalonyl-CoA Mutase Deficiency
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-003779-75 Sponsor Protocol Number: ENDURANCE Start Date*: 2018-06-07
    Sponsor Name:Hospital Universitario La Paz
    Full Title: Randomized clinical trial to assess the impact of treatment with empagliflozine on systemic inflammatory and renal parameters in patients with Diabetes Mellitus type 2 and ischemic heart disease.
    Medical condition: Type 2 Diabetes Mellitus
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-002736-10 Sponsor Protocol Number: MVPV1 Start Date*: 2006-01-20
    Sponsor Name:Royal Marsden Hospital
    Full Title: Open, Randomised Phase II Study Assessing The Toxicity And Efficacy Of Platinum-Based Chemotherapy With Vitamin Supplementation In The Treatment Of Lung Cancer
    Medical condition: Non-small cell lung cancer Small-cell lung cancer Malignant Mesothelioma (ICD classification code:C45.9)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-000614-21 Sponsor Protocol Number: 7168K01 Start Date*: 2007-08-09
    Sponsor Name:Zambon Group S.p.A
    Full Title: A multicentre, open-label study to evaluate the efficacy and safety of 5-MTHF administration, added on to the individual established therapy, on plasma homocysteine levels in patients with congenit...
    Medical condition: homocystinuria
    Disease: Version SOC Term Classification Code Term Level
    8.1 10020365 pref
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: AT (Completed) SK (Completed) HU (Completed) GB (Prematurely Ended)
    Trial results: View results
    Download Options:
    Number of Trials to download:
    Download Content:
    Download Format:
    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
    1  2  Next»
    Query did not match any studies.
    For support, Contact us.
    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

    European Medicines Agency © 1995-Mon May 20 00:30:36 CEST 2024 | Domenico Scarlattilaan 6, 1083 HS Amsterdam, The Netherlands
    EMA HMA