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Clinical trials for Hyperalgesia

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    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

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    82 result(s) found for: Hyperalgesia. Displaying page 1 of 5.
    1  2  3  4  5  Next»
    EudraCT Number: 2008-008475-34 Sponsor Protocol Number: Remi-Sunburn-1 Start Date*: 2009-02-25
    Sponsor Name:Abteilung für Anaesthesie und Intensivmedizin, Medizinische Universität Wien
    Full Title: The effect of remifentanil on the reversal of established sunburn-induced hyperalgesia in human volunteers.
    Medical condition: This is a volunteer study in healthy volunteers. Pain research, reversal of hyperalgesia by IMP is studied
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2009-011599-31 Sponsor Protocol Number: RemiAnes1 Start Date*: 2009-06-26
    Sponsor Name:Abteilung für Anaesthesie und Intensivmedizin, Medizinische Universität Wien
    Full Title: The effect of high-dose remifentanil on the reversal of established capsaicin-induced hyperalgesia in human volunteers
    Medical condition: This is a volunteer study in healthy volunteers. Pain research, reversal of hyperalgesia by IMP ist studied
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2008-003605-13 Sponsor Protocol Number: Remi-Capsaicin-2 Start Date*: 2008-12-03
    Sponsor Name:Abteilung für Anaesthesie und Intensivmedizin, Medizinische Universität Wien
    Full Title: The effect of remifentanil on the reversal of established capsaicin-induced hyperalgesia in human volunteers
    Medical condition: This is a volunteer study in healthy volunteers. Pain research, reversal of hyperalgesia by IMP is studied.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2007-004549-14 Sponsor Protocol Number: Remi-Capsaicin-1 Start Date*: 2008-02-15
    Sponsor Name:Department of Anaesthesie, General Intensive Care and Pain Therapy, Medical University of Vienna [...]
    1. Department of Anaesthesie, General Intensive Care and Pain Therapy, Medical University of Vienna
    2.
    Full Title: A novel role for remifentanil: the reversal of established capsaicin-induced hyperalgesia.
    Medical condition: This is a volunteer study in healthy volunteers. Pain research, reversal of hyperalgesia by IMP is studied.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2017-003278-15 Sponsor Protocol Number: AGO/2017/005 Start Date*: 2017-12-14
    Sponsor Name:Ghent University Hospital
    Full Title: Hyperalgesia, Persistent Pain, and Fentanyl Dosing in On-Pump Coronary Artery Bypass Grafting
    Medical condition: Secondary wound hyperalgesia Persistent Pain
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2009-015780-14 Sponsor Protocol Number: High-Dose-RemiSun Start Date*: 2009-12-28
    Sponsor Name:Abteilung für Anästhesie und Intensivmedizin, Medizinische Universität Wien
    Full Title: The effect of high dose remifentanil on the reversal of established sunburn-induced hyperalgesia in human volunteers
    Medical condition: Volunteer study with 24 healthy volunteers to perform pain research and to study the reversal of hyperalgesia by IMP
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2012-005663-27 Sponsor Protocol Number: HDNX Start Date*: 2013-02-27
    Sponsor Name:HOC, Rigshospitalet
    Full Title: Effect of a late naloxone-infusion on secondary hyperalgesia after a first degree heat injury.
    Medical condition: First degree burn injury in healthy volunteers
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004852 10020573 Hyperalgesia LLT
    Population Age: Adults Gender: Male
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-001639-30 Sponsor Protocol Number: TramaPara8405 Start Date*: 2006-10-02
    Sponsor Name:Department of Anaesthesia&Intensive Care B, Vienna Medical University
    Full Title: Investigation of the antihyperalgesic effect of a combination of tramadol and paracetamol on primary and secondary hyperalgesia in an UV-B induced inflammatory skin pain model in healthy volunteers.
    Medical condition: This is a volunteer study in healthy volunteers.
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2015-003208-22 Sponsor Protocol Number: CaPsaPPP-01 Start Date*: 2015-11-06
    Sponsor Name:Wilhelminen hospital
    Full Title: Does a two-day pretreatment with capsaicin reduce postoperative hyperalgesia and pain in surgical patients A prospective, randomized, double-blind, placebo-controlled, parallel group, single-cente...
    Medical condition: postoperative secondary mechanical hyperalgesia and postoperative pain
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-005211-28 Sponsor Protocol Number: 20041221 Start Date*: 2005-07-20
    Sponsor Name:Department of Anesthesiology, University Hospital of Erlangen
    Full Title: A double-blind placebo-controlled four period crossover study of paracetamol and tramadol in the electrical hyperalgesia model of central sensitisation in healthy volunteers
    Medical condition: The primary aim of the present study is to investigate the effects of intravenous paracetamol and tramadol and their combination on the experimentally-induced central sensitization in an electrical...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2004-004953-24 Sponsor Protocol Number: 20041202 Start Date*: 2005-07-20
    Sponsor Name:Department of Anesthesiology, University Hospital Erlangen
    Full Title: A double-blind placebo-controlled two period crossover study of pregabalin and aprepitant in the electrical hyperalgesia model of central sensitisation in healthy volunteers
    Medical condition: The primary aim of the present study is therefore to investigate the effects of oral pregabalin and aprepitant on experimentally-induced central sensitization in the electrical hyperalgesia model, ...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-004796-35 Sponsor Protocol Number: EPICLO2006 Start Date*: 2007-04-20
    Sponsor Name:R&D Department, Box 146, Addenbrooke's Hospital
    Full Title: A study of effect of epidural clonidine on postoperative pain relief, hyperalgesia and chronic pain in patients undergoing colorectal surgery
    Medical condition: 1. Postoperative pain and hyperalgesia following laparotomy for colorectal surgery 2. Chronic pain following laparotomy for colorectal surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-004426-93 Sponsor Protocol Number: lido_caps_sb_200509 Start Date*: 2005-10-28
    Sponsor Name:Department of Anaesthesia and General Intensive Care Medicine
    Full Title: Investigation of antihyperalgesic effect...
    Medical condition: volunteer study with healthy volunteers using the intradermal capsaicin injection and UV-B sunburn as models of hyperalgesia
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2011-002734-39 Sponsor Protocol Number: 010911 Start Date*: 2012-03-09
    Sponsor Name:Oslo University Hospital
    Full Title: Opioid Induced Hyperalgesia: possible to avoid by gradual reduction compared to acute withdrawal from remifentanil?
    Medical condition: Opioid Induced Hyperalgesia
    Disease: Version SOC Term Classification Code Term Level
    14.0 10018065 - General disorders and administration site conditions 10033376 Pain aggravated LLT
    Population Age: Adults Gender: Male
    Trial protocol: NO (Completed)
    Trial results: View results
    EudraCT Number: 2006-000875-14 Sponsor Protocol Number: ALS-7-05-A-401 Start Date*: 2006-07-06
    Sponsor Name:AIR LIQUIDE SANTE INTERNATIONAL
    Full Title: Short-, and long-term effects of the intra-operative nitrous oxide administration on the remifentanil-induced post-operative hyperalgesia, morphine consumption and long-term quality of life
    Medical condition:
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed) AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-020042-94 Sponsor Protocol Number: LS07-040 Start Date*: 2010-09-02
    Sponsor Name:Medizinische Universität Wien, Universitätsklinik für Anästhesie, Allgemeine Intensivmedizin
    Full Title: The Effect of High-dose Remifentanil on the Reversal of Neuropathic Pain in Postherpetic Patients
    Medical condition: Post herpetic hyperalgesia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2012-000839-54 Sponsor Protocol Number: SMi-MW-12 Start Date*: 2012-06-07
    Sponsor Name:Rigshospitalet
    Full Title: The effect of late naloxon-infusion on secondary hyperalgesia after a first degree burn injury
    Medical condition: Induced pain in volunteers
    Disease: Version SOC Term Classification Code Term Level
    14.1 10018065 - General disorders and administration site conditions 10033371 Pain PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-005627-32 Sponsor Protocol Number: IIVOP Start Date*: 2014-06-12
    Sponsor Name:Cambridge University Hospitals NHS Foundation Trust and the University of Cambridge
    Full Title: A randomised, double blind, placebo controlled crossover study of the influence of the HCN channel blocker ivabradine in a healthy volunteer pain model - an enriched population study
    Medical condition: Neuropathic Pain
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004852 10054095 Neuropathic pain LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-005426-19 Sponsor Protocol Number: 51237 Start Date*: 2016-02-09
    Sponsor Name:Rigshospitalet, Copenhagen University Hospitals
    Full Title: "Effect of High-dose Target-controlled Naloxone Infusion on Pain and Hyperalgesia in Patients following Recovery from Impacted Mandibular Third Molar Extraction. A Randomized, Placebo-controlled, ...
    Medical condition: Healthy volunteers (n = 94) are included. The main study includes 14 subjects who have had an uncomplicated, impacted mandibular, third molar extraction 4-5 weeks prior to participation in the stud...
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004867 10049475 Chronic pain LLT
    Population Age: Adults Gender: Male
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-000595-37 Sponsor Protocol Number: 1111111 Start Date*: 2020-12-02
    Sponsor Name:Fakultní nemocnice v Motole
    Full Title: Pharmacokinetics and pharmacodynamics of levobupivacaine during continuous caudal epidural analgesia in newborns
    Medical condition: The primary aim of study is to determine PK and PD of levobupivacaine in newborns (premature included). And discover or decline of LA cumulation. The secondary aim of the study is to obtain enough ...
    Disease:
    Population Age: Preterm newborn infants, Newborns, Under 18 Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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