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Clinical trials for Hypoxia

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44365   clinical trials with a EudraCT protocol, of which   7389   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    161 result(s) found for: Hypoxia. Displaying page 1 of 9.
    1  2  3  4  5  6  7  8  9  Next»
    EudraCT Number: 2008-005985-30 Sponsor Protocol Number: rosucaf2 Start Date*: 2009-01-22
    Sponsor Name:Department of Pharmacology-Toxicology
    Full Title: Is augmentation of PORH by rosuvastatin adenosine-receptor mediated?
    Medical condition: mechanism of influence of statins on human adaptive mechanisms in hypoxic circumstances
    Disease: Version SOC Term Classification Code Term Level
    9.1 10021143 Hypoxia LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-003363-25 Sponsor Protocol Number: NA Start Date*: 2020-08-18
    Sponsor Name:Department of Intensive Care, Rigshospitalet
    Full Title: Higher vs. Lower Doses of Dexamethasone in Patients with COVID-19 and Severe Hypoxia: the COVID STEROID 2 trial
    Medical condition: Adult patients with COVID-19 and severe hypoxia.
    Disease: Version SOC Term Classification Code Term Level
    23.1 100000004862 10084401 COVID-19 respiratory infection LLT
    21.1 10038738 - Respiratory, thoracic and mediastinal disorders 10021143 Hypoxia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2019-000804-14 Sponsor Protocol Number: OPHT-070119 Start Date*: 2019-05-10
    Sponsor Name:Medical University of Vienna, Department of Clinical Pharmacology
    Full Title: The effect of hyperoxia and hypoxia on fluorescence lifetime imaging ophthalmoscopy in healthy subjects
    Medical condition: healthy volunteers
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-014260-19 Sponsor Protocol Number: CH/2009/3187 Start Date*: 2010-01-29
    Sponsor Name:University Hospital Bristol NHS Foundation Trust
    Full Title: A feasibility study of adding xenon to cooling therapy in babies at high risk of brain injury following poor condition at birth
    Medical condition: Neonatal hypoxia-ischaemia (HI). There is no exact MedDRA term for this. The closest MedDRA terms matching this are neonatal asphyxia and neonatal hypoxia.
    Disease: Version SOC Term Classification Code Term Level
    12 10028923 Neonatal asphyxia LLT
    12 10028923 Neonatal asphyxia PT
    12 10028946 Neonatal hypoxia and asphyxia HLT
    12 10050081 Neonatal hypoxia LLT
    12 10050081 Neonatal hypoxia PT
    Population Age: Newborns, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-002251-33 Sponsor Protocol Number: 01 Start Date*: 2006-10-10
    Sponsor Name:University of Vienna
    Full Title: Hypoxia Imaging with the novel Radiopharmaceutical 18F Fluoroazomycin Arabinoside (FAZA)- Prognostic impact in Cervical Cancer .
    Medical condition: Twenty-five patients with cervical carcinoma (T2Nx or TxN1) will be included in the present study. In addition to the routine pre-therapeutical staging of cervical cancer, 18FAZA PET will be perfor...
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2016-003621-41 Sponsor Protocol Number: DESIRED Start Date*: 2016-12-05
    Sponsor Name:Department of Endocrinology, Metabolism and Diabetes, Karolinska University Hospital
    Full Title: Desferal administration to improve the impaired reaction to hypoxia in diabetes (DESIRED) A randomised, double-blind, placebo-controlled, cross-over study
    Medical condition: The study will investigate the effect of deferoxamine on the impaired reaction to hypoxia in patients with diabetes mellitus type 1.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2020-001375-32 Sponsor Protocol Number: PreToVid Start Date*: 2020-04-03
    Sponsor Name:UMCG
    Full Title: Pre-emptive tocilizumab in hypoxic COVID-19 patients, a prospective randomized trial
    Medical condition: Hypoxia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2008-000540-14 Sponsor Protocol Number: HIGHCARE Start Date*: 2008-05-20
    Sponsor Name:ISTITUTO AUXOLOGICO ITALIANO
    Full Title: Role of the renin-angiotensin system in the cardiovascular, metabolic, neurologic and respiratory response to hypobaric hypoxia during sustained exposure to high altitude.
    Medical condition: This study is aimed at the investigation of adaptative physiological mechanisms at high altitude and not at the development of new therapeutic indications.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10007541 Cardiac disorders SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-002390-21 Sponsor Protocol Number: Oxygen_Inflammation Start Date*: 2013-09-03
    Sponsor Name:Radboud University Nijmegen Medical Centre
    Full Title: Effects of oxygen status on endotoxemia induced inflammation and Hypoxia Inducible Factor 1-a. A pilot proof of principle study.
    Medical condition: Possible future indications: inflammatory conditions in general, autoimmune diseases
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2012-001049-42 Sponsor Protocol Number: Start Date*: 2012-07-05
    Sponsor Name:Department of Oncology, Rigshospitalet
    Full Title: MRI-perfusion and FLT- and FET-PET during bevacizumab monotherapy for patients with recurrent Glioblastoma Multiforme
    Medical condition: Recurrent Glioblastoma multiforme
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2021-000592-36 Sponsor Protocol Number: CGRPAMS03 Start Date*: 2023-07-10
    Sponsor Name:Universitätsklinikum Essen
    Full Title: Calcitonin Gene-Related Peptide Receptor Antagonists for Prevention of Acute Mountain Sickness
    Medical condition: Acute Mountain Sickness (AMS) is a constellation of symptoms (headache, anorexia, nausea, vomiting, lightheadedness, and fatigue) occuring in unacclimatized mountaineers ascending too fast, too high
    Disease: Version SOC Term Classification Code Term Level
    20.0 10022117 - Injury, poisoning and procedural complications 10020045 High altitude illness LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2010-019225-33 Sponsor Protocol Number: 31630 Start Date*: 2010-05-18
    Sponsor Name:
    Full Title: A Randomized Phase II Study Of Reirradiation And Hyperthermia Versus Reirradiation And Hyperthermia Plus Chemotherapy For Locally Recurrent Breast Cancer In Previously Irradiated Area
    Medical condition: All patients with a local regional recurrence of invasive breast cancer in previously irradiated area with measurable lesions not suitable for resection are eligible for this trial. Patients with m...
    Disease: Version SOC Term Classification Code Term Level
    12.1 10008456 Chemotherapy single agent systemic LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2013-004478-80 Sponsor Protocol Number: Issue1 Start Date*: 2014-01-08
    Sponsor Name:University Hospital Bristol NHS Foundation Trust
    Full Title: XENON AND COOLING THERAPY IN BABIES AT HIGH RISK OF BRAIN INJURY FOLLOWING POOR CONDITION AT BIRTH: A RANDOMISED OUTCOME STUDY (COOLXENON3 STUDY)
    Medical condition: Neonatal hypoxia-ischaemia (HI). There is no exact MedDRA term for this. The closest MedDRA terms matching this are neonatal asphyxia and neonatal hypoxia.
    Disease: Version SOC Term Classification Code Term Level
    16.1 10038738 - Respiratory, thoracic and mediastinal disorders 10028923 Neonatal asphyxia PT
    16.1 100000004868 10028946 Neonatal hypoxia and asphyxia HLT
    16.1 10038738 - Respiratory, thoracic and mediastinal disorders 10050081 Neonatal hypoxia PT
    Population Age: Newborns, Under 18 Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2015-005222-19 Sponsor Protocol Number: BREATH Start Date*: 2016-07-14
    Sponsor Name:Leiden University Medical Center
    Full Title: Effect of neuromuscular blockade and reversal by sugammadex versus neostigmine on breathing when hypoxic or hypercapnic in volunteers
    Medical condition: Postoperative ventilatory control
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004855 10038680 Respiratory depression postoper LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-001395-15 Sponsor Protocol Number: Awaiting Start Date*: 2020-04-06
    Sponsor Name:Deparment of Intensive Care, Rigshospitalet
    Full Title: Low dose hydrocortisone in patients with COVID-19 and severe hypoxia – the COVID STEROID trial
    Medical condition: Adult patients with COVID-19 and severe hypoxia.
    Disease: Version SOC Term Classification Code Term Level
    23.0 100000004862 10053983 Corona virus infection LLT
    21.1 10038738 - Respiratory, thoracic and mediastinal disorders 10021143 Hypoxia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-003781-17 Sponsor Protocol Number: CCM S78/407 Start Date*: 2007-07-16
    Sponsor Name:FONDAZIONE MONZINO CENTRO CARDIOLOGICO
    Full Title: COMPARED EFFECTS OF THREE DIFFERENT BETA BLOCKERS (CARVEDILOL, BISOPROLOL AND NEBIVOLOL) ON EXERCISE CAPACITY, PULMONARY FUNCTION AND RESPONSE TO HYPOXIA IN CHRONIC HEART FAILURE
    Medical condition: chronic heart failure
    Disease: Version SOC Term Classification Code Term Level
    6.1 10007558 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-002119-41 Sponsor Protocol Number: CE2261 Start Date*: 2014-11-12
    Sponsor Name:Institut Jules Bordet
    Full Title: Influence of a new model of relative hypoxia on the evolution of erythropoietin and haemoglobin in patients undergoing breast reconstruction by a Deep Inferior Epigastric Perforator Flap.
    Medical condition: Anaemia induced post operatively by hemodilution and surgical blood loss
    Disease: Version SOC Term Classification Code Term Level
    17.0 10022891 - Investigations 10053795 Blood erythropoietin increased PT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-000224-17 Sponsor Protocol Number: 11-36-14/12 Start Date*: 2014-09-15
    Sponsor Name:MAASTRO Clinic
    Full Title: Non invasive imaging of [18F]HX4 with Positron-Emission-Tomography (PET) in Cervix Cancer.
    Medical condition: Eligible patients with squamous cell carcinoma, adenocarcinoma or adenosquamous carcinoma (FIGO stage IB – IVA), to be treated with curative radiation treatment either or not combined with concurr...
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2011-001812-80 Sponsor Protocol Number: 11-12-23/03-intern-6470 Start Date*: 2011-11-25
    Sponsor Name:Maastro Clinic
    Full Title: Non invasive imaging of [18F]HX4 with Positron-Emission-Tomography (PET) in Head and Neck Cancer.
    Medical condition: Patients with histological or cytological confirmed squamous cell carcinomas of the oral cavity, oropharynx, hypopharynx, larynx, T2-T3-T4, any N, M0
    Disease: Version SOC Term Classification Code Term Level
    14.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10067821 Head and neck cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2010-022842-26 Sponsor Protocol Number: UMCNONCO201004 Start Date*: 2010-11-25
    Sponsor Name:University Medical Centre Nijmegen
    Full Title: Autophagy inhibition using hydrochloroquine in breast cancer patients: a pilot study
    Medical condition: proven invasive adenocarcinoma of the breast
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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