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Clinical trials for Large intestine

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    247 result(s) found for: Large intestine. Displaying page 1 of 13.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2012-002327-15 Sponsor Protocol Number: KFE12.05 Start Date*: 2013-02-27
    Sponsor Name:Odense University Hospital
    Full Title: Phase II study with temozolomide and capecitabine for patients with refractory colorectal cancer
    Medical condition: Patients with refractory colorectal cancer
    Disease: Version SOC Term Classification Code Term Level
    16.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10010023 Colorectal neoplasms malignant HLT
    16.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10061451 Colorectal cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2007-007059-14 Sponsor Protocol Number: GlutOxa2007 Start Date*: 2007-11-15
    Sponsor Name:AZIENDA DI RILIEVO NAZIONALE E DI ALTA SPECIALIZZAZIONE OSPEDALE CIVICO E BENFRATELLI, G.DI CRISTINA E M.ASCOLI
    Full Title: Role of the Glutatione reduced in the prevention of neuro-toxicity from Oxaliplatino.
    Medical condition: Patients with neoplasia malignant.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10010023 Colorectal neoplasms malignant HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-001179-13 Sponsor Protocol Number: 16891 Start Date*: 2008-01-24
    Sponsor Name:Dutch Cancer Society
    Full Title: Neo-adjuvant Simvastatin therapy in colorectal cancer
    Medical condition: Colorectal cancer
    Disease: Version SOC Term Classification Code Term Level
    9.1 10010023 Colorectal neoplasms malignant HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-004200-36 Sponsor Protocol Number: BRTA-0100-014 Start Date*: 2005-12-02
    Sponsor Name:NERVIANO MEDICAL SCIENCES
    Full Title: Phase II exploratory study of brostallicin PNU-166196A as third/fourth line chemoterapy in adult patients with advanced/metastatic colorectal cancer CRC .
    Medical condition: Use for the treatment of advanced/metastatic colorectal cancer, as third/fourth line chemioterapy.
    Disease: Version SOC Term Classification Code Term Level
    6.1 10010023 HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-011763-37 Sponsor Protocol Number: ADAVEGF-01 Start Date*: 2009-07-22
    Sponsor Name:ISTITUTO CLINICO HUMANITAS
    Full Title: THE ANTI-ANGIOGENIC EFFECTS OF ADALIMUMAB IN CROHN`S DISEASE
    Medical condition: Crohn`s Disease
    Disease: Version SOC Term Classification Code Term Level
    9.1 10038283 Regional enteritis of small intestine with large intestine LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-004849-42 Sponsor Protocol Number: 88/2006/O/Sper Start Date*: 2006-11-02
    Sponsor Name:AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI
    Full Title: Cetuximab + Irinotecano vs chemoterapia standard nel carcinoma colo-rettale avanzato pretrattato non resecabile esprimente EGFR
    Medical condition: carcinoma colo-rettale avanzato
    Disease: Version SOC Term Classification Code Term Level
    9.1 10010023 Colorectal neoplasms malignant HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2012-002128-33 Sponsor Protocol Number: 004-IRCC-10IIS-12 Start Date*: 2012-05-29
    Sponsor Name:FONDAZIONE DEL PIEMONTE PER L'ONCOLOGIA IRCC DI CANDIOLO
    Full Title: Open-Label, Phase II Study of Trastuzumab in Combination with Lapatinib or Pertuzumab in Combination with Trastuzumab in Patients with HER2-positive Metastatic Colorectal Cancer: the HERACLES Trial...
    Medical condition: Metastatic colorectal carcinoma (mCRC)
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004864 10010023 Colorectal neoplasms malignant HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-005603-32 Sponsor Protocol Number: K357 Start Date*: 2012-09-17
    Sponsor Name:German Cancer Research Center (DKFZ)
    Full Title: Use of acetylsalicylic acid (ASA) for enhanced early detection of colorectal neoplasms
    Medical condition: Early detection of Colorectal neoplasms
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004864 10010023 Colorectal neoplasms malignant HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2012-002766-13 Sponsor Protocol Number: 1088/12 Start Date*: 2013-01-24
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: A phase 2 study of temozolomide in patients affected by metastatic colonrectal cancer with hypermethylation of 06-methylguanine-dna-methyltransferase
    Medical condition: metastatic colonrectal cancer
    Disease: Version SOC Term Classification Code Term Level
    15.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10010023 Colorectal neoplasms malignant HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-001986-18 Sponsor Protocol Number: CMEK162X2116 Start Date*: 2013-11-12
    Sponsor Name:Array BioPharma Inc.
    Full Title: A phase Ib/II, open-label, multi-center, dose escalation study of MEK162 in combination with panitumumab in adult patients with mutant RAS or wild-type RAS metastatic colorectal cancer
    Medical condition: Mutant RAS or wild-type (WT) RAS metastatic colorectal cancer
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10052358 Colorectal cancer metastatic PT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10010023 Colorectal neoplasms malignant HLT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10010030 Colorectal cancer recurrent PT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10061451 Colorectal cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) BE (Completed) IT (Prematurely Ended) NL (Completed) DE (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2008-001499-55 Sponsor Protocol Number: RESCORE Start Date*: 2008-05-08
    Sponsor Name:Turku PET Centre
    Full Title: Treatment Monitoring of Advanced Colorectal cancer with 18F-FDG PET/CT
    Medical condition: Advanced colorectal cancer
    Disease: Version SOC Term Classification Code Term Level
    9.1 10010029 Colorectal cancer NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-005451-15 Sponsor Protocol Number: IPR/12 Start Date*: 2006-12-29
    Sponsor Name:MOLMED
    Full Title: NGR006 A phase II study of NGR-hTNF administered as single agent every 3 weeks in patients affected by colorectal cancer CRC , previously treated with fluoropyrimidine, oxaliplatin and irinotecan...
    Medical condition: Patients affected by advanced or metastatic colorectal cancer CRC.
    Disease: Version SOC Term Classification Code Term Level
    10061451 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-017384-42 Sponsor Protocol Number: 838 Start Date*: 2010-05-17
    Sponsor Name:Academisch ziekenhuis Leiden acting under the name of Leids Universitair Medisch Centrum
    Full Title: Safety and efficacy of the addition of simvastatin to cetuximab in k-ras mutant advanced or metastatic colorectal cancer patients. A single-arm, multicenter, phase II study using a Simon two stage ...
    Medical condition: k-ras mutant advanced or metastatic colorectal cancer failing prior 5-FU, oxaliplatin, and irinotecan containing regimens.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10061451 Colorectal cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-017620-11 Sponsor Protocol Number: KINURA-2 Start Date*: 2011-06-14
    Sponsor Name:Scheper Ziekenhuis
    Full Title: Onderzoek naar de farmacokinetiek van uracil na orale toediening bij patiënten met colorectaal carcinoom.
    Medical condition: Colorectal cancer
    Disease: Version SOC Term Classification Code Term Level
    12.1 10010036 Colorectal carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-002981-11 Sponsor Protocol Number: ThromboCa Start Date*: 2013-09-24
    Sponsor Name:Medizinische Universität Wien, Klinik für Innere Medizin III, Abteilung für Gastroenterologie und Hepatologie
    Full Title: Iron Deficiency, Platelet Phenotype and Thromboembolism in Cancer Patients
    Medical condition: colorectal cancer, iron deficiency
    Disease: Version SOC Term Classification Code Term Level
    16.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10061451 Colorectal cancer PT
    16.0 10027433 - Metabolism and nutrition disorders 10022970 Iron deficiency PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-002101-65 Sponsor Protocol Number: PI17/01109 Start Date*: 2018-11-19
    Sponsor Name:Ángel Lanas Arbeloa-Instituto de Investigación Sanitaria Aragón
    Full Title: Assessment of direct biomarkers of aspirin action to develop a precision chemoprevention therapy of colorectal cancer
    Medical condition: Colorectal cancer with a recent confirmed diagnosis (less than 48h)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10061451 Colorectal cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-003831-21 Sponsor Protocol Number: 2277/2007 Start Date*: 2007-07-18
    Sponsor Name:AZIENDA OSPEDALIERA PISANA
    Full Title: PHARMACOKINETIC PERSPECTIVE STUDY IN COLORECTAL CANCER PATIENTS AND CANDIDATE FOR FLUOROPYRIMIDINE THERAPY: 5-FLUORO TEST
    Medical condition: Colo-rectal adenocarcinoma.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10061451 Colorectal cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-003458-81 Sponsor Protocol Number: GOLF-IG2 Start Date*: 2005-06-28
    Sponsor Name:AZIENDA OSPEDALIERA SENESE
    Full Title: A randomized phase III trial on first line metastatic colorectal carcinoma GOLFIG gemcitabine FOLFOX-4 GM-CSF and interleukin 2 chemo-immunotherapy vs standard FOLFOX-4 chemotherapy
    Medical condition: CHEMIO-IMMUNOTHERAPY IN ADVANCED COLON-CANCER
    Disease: Version SOC Term Classification Code Term Level
    10061451 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-001648-79 Sponsor Protocol Number: KFE13.10 Start Date*: 2013-07-22
    Sponsor Name:Odense University Hospital
    Full Title: Epirubicin as 2nd line treatment to patients with TOP2A gene amplified and oxaliplatin refractory metastatic colerectal cancer
    Medical condition: TOP2A gene amplified and oxaliplatin refractory metastatic colorectal cancer
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10061451 Colorectal cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2009-009863-75 Sponsor Protocol Number: CEAEP_2009-05-29 Start Date*: 2009-08-26
    Sponsor Name:Karolinska Institutet/ Hospital
    Full Title: El-porCEA: Assessment of safety and immunogenicity of intradermal electroporation of tetwtCEA DNA in patients with colorectal cancer.
    Medical condition: Colorectal carcinoma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10010036 Colorectal carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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