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Clinical trials for Methadone maintenance

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
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    The EU Clinical Trials Register currently displays   44339   clinical trials with a EudraCT protocol, of which   7369   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

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    16 result(s) found for: Methadone maintenance. Displaying page 1 of 1.
    EudraCT Number: 2005-000108-15 Sponsor Protocol Number: KCL/SLAM-CT2005-01 Start Date*: 2005-03-11
    Sponsor Name:Institute of Psychiatry, Kings College London & South London and Maudsley NHS Trust
    Full Title: Pharmacokinetic and pharmacodynamic properties of oral, intramuscular and intravenous methadone in methadone maintenance patients
    Medical condition: Opioid dependence
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Temporarily Halted)
    Trial results: (No results available)
    EudraCT Number: 2005-000240-82 Sponsor Protocol Number: P04279 Start Date*: 2005-05-05
    Sponsor Name:AESCA Pharma GesmbH
    Full Title: Randomized, controlled Study of Methadone and Buprenrphine in Hepatitis C patients in need of treatment
    Medical condition: hepatitis C patients with a history of intravenous drug abuse, who are willing to undergo methadone or buprenorphine substitution
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2004-003175-36 Sponsor Protocol Number: KCL/SLaM-CT2004-3 Start Date*: 2007-07-26
    Sponsor Name:Kings College London/South London and Maudsley NHS Foundation Trust
    Full Title: Randomised controlled trial of injectable opioid treatment for heroin dependence (RIOTT)
    Medical condition: Opioid dependence, ICD classification code F11.2 (ICD-10)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-004775-36 Sponsor Protocol Number: DETOX-11 Start Date*: 2012-01-30
    Sponsor Name:GET SRL
    Full Title: ''A Phase III, multicenter, open-label study, to evaluate the efficacy and safety of different dosage regimens of 0.2 mg lofexidine hydrochloride (DIMATEX) in the treatment of withdrawal symptoms d...
    Medical condition: Oppiate addicts(heroin, methadone and buprenorphine)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10037175 - Psychiatric disorders 10032707 Other specified drug dependence, continuous use LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2008-005028-10 Sponsor Protocol Number: FARM7PER7 Start Date*: 2008-10-14
    Sponsor Name:Universita' di Firenze; Dipartimento di Farmacologia Preclinica e Clinica
    Full Title: Methadone dose adjustments, plasma R-methadone levels and therapeutic outcome of opioid addiction
    Medical condition: Heroin dependence
    Disease: Version SOC Term Classification Code Term Level
    9.1 10029205 Nervous system disorders SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-004482-41 Sponsor Protocol Number: SUB3001 Start Date*: 2006-04-07
    Sponsor Name:Napp Pharmaceuticals Research Limited
    Full Title: A randomised, double blind, double-dummy, parallel group study to compare the efficacy and tolerability of morphine sulphate prolonged release capsules and methadone oral solution in once per day a...
    Medical condition: Subjects have a diagnosis of opiate addiction.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-002237-11 Sponsor Protocol Number: ARC Start Date*: 2012-12-17
    Sponsor Name:King's College London [...]
    1. King's College London
    2. South London and Maudsley NHS Foundation Trust
    Full Title: Effectiveness of Adaptive Opioid Agonist Maintenance Pharmacotherapy and Behavioural Therapy for Opioid Use Disorder.
    Medical condition: Opiate dependency disorder
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2015-002440-13 Sponsor Protocol Number: OMT-Satisfaction Start Date*: 2015-12-15
    Sponsor Name:Medical University Innsbruck
    Full Title: Treatment satisfaction and self-reported symptoms in patients under opioid maintenance therapy
    Medical condition: Opioid maintenance treatment (OMT) is an important factor in the medical care of opioid-dependent patients. Qualified OMT combined with general medical care and psychosocial support is effective in...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-002185-60 Sponsor Protocol Number: SUB9001 Start Date*: 2009-07-09
    Sponsor Name:Mundipharma Medical Company, Basel
    Full Title: RANDOMISED, CONTROLLED CLINICAL STUDY REGARDING THE FEASIBILITY OF CONVERTING OPIATE DEPENDENTS FROM METHADONE SUBSTITUTES TO SLOW RELEASE MORPHINE SULPHATE (SEVRE-LONG®)
    Medical condition: Patients with an opioid or multiple substance dependence (including opioids), actually enrolled in a methadone maintenance therapy in one of the study centres (ICD classifications F11.22, F19.22).
    Disease: Version SOC Term Classification Code Term Level
    9.1 10052970 Drug withdrawal maintenance therapy LLT
    9.1 10052730 Drug withdrawal therapies HLT
    9.1 10043413 Therapeutic procedures and supportive care NEC HLGT
    9.1 10012346 Dependence on opiates LLT
    9.1 10013663 Drug dependence LLT
    9.1 10064465 Substance-related disorders HLT
    9.1 10037176 Psychiatric disorders NEC HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2013-004024-11 Sponsor Protocol Number: 60-60600-97-103 Start Date*: 2014-07-23
    Sponsor Name:Academic Psychiatric Center - AMC-UvA
    Full Title: New pharmacotherapeutic treatment options for crack-cocaine dependent people in the Netherlands: A double-blind, placebo-controlled randomized feasibility study of sustained release dexamphetamine
    Medical condition: cocaine dependence (according DSM-IV)
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004873 10009817 Cocaine dependence LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2010-018326-39 Sponsor Protocol Number: CB-2010-01 Start Date*: 2010-04-20
    Sponsor Name:Department of Genito-Urinary Medicine and Infectious Diseases
    Full Title: An open-label, randomised pilot study comparing the efficacy, safety and tolerability of raltegravir with protease inhibitor-based therapy in treatment-naïve, HIV/Hepatitis C co-infected injecting ...
    Medical condition: HIV-1/Hepatitis C co-infected patients
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10020161 HIV infection PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2018-004460-63 Sponsor Protocol Number: EXPO Start Date*: 2019-07-01
    Sponsor Name:South London and Maudsley NHS Foundation Trust [...]
    1. South London and Maudsley NHS Foundation Trust
    2. King's College London
    Full Title: Extended-release Pharmacotherapy for Opioid Use Disorder (EXPO): An Open Label Randomised Controlled Trial of Injectable Depot Maintenance Buprenorphine versus Standard-Of-Care Oral Maintenance Opi...
    Medical condition: Opiod addiction
    Disease: Version SOC Term Classification Code Term Level
    23.1 10037175 - Psychiatric disorders 10013658 Drug addiction LLT
    20.0 10037175 - Psychiatric disorders 10037175 Psychiatric disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2005-002544-25 Sponsor Protocol Number: CL_700_002_PRO-AME3 Start Date*: 2006-01-02
    Sponsor Name:LAB Pharma Ltd
    Full Title: A Multicentre, Multinational, Open-Label Trial (including Double-Blind, Placebo-Controlled Cross-Over Extension Part) to Evaluate the Time to Significant Pain Relief with Fentanyl TAIFUN® in the Tr...
    Medical condition: Patients with cancer having episodes of breakthrough pain
    Disease: Version SOC Term Classification Code Term Level
    7.1 10058019 canc
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-019981-94 Sponsor Protocol Number: ADOP Start Date*: 2010-09-21
    Sponsor Name:HUS/ Neuropsykiatrian poliklinikka
    Full Title: Attention Deficit Hyperactivity Disorder (ADHD) and opioid maintenance therapy. A randomized, placebo-controlled study of the efficacy of atomoxetine for treating adult ADHD in patients receiving o...
    Medical condition: Patients will be recruited from out-patient clinics treating opioid dependent patients with buprenorphine or methadone maintenance therapy. Patients will be screened for ADHD symptoms. Based on the...
    Disease: Version SOC Term Classification Code Term Level
    12.1 10064104 ADHD LLT
    Population Age: Gender: Male, Female
    Trial protocol: FI (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2011-001088-28 Sponsor Protocol Number: BRIO Start Date*: 2016-01-14
    Sponsor Name:South London and Maudsley NHS Foundation Trust [...]
    1. South London and Maudsley NHS Foundation Trust
    2. King's College London
    Full Title: Feasibility, efficacy and acceptability of injected buprenorphine as treatment for opiate users who persist in injecting illicit heroin through opiate maintenance treatment
    Medical condition: Addiction to illicit heroin
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004873 10019935 Heroin addiction LLT
    18.1 100000004873 10001127 Addiction to drugs LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2022-001997-70 Sponsor Protocol Number: EXCELLENCE/0421/0543v1 Start Date*: 2022-11-16
    Sponsor Name:University of Cyprus
    Full Title: Efficacy of Ketamine for the Prevention of Relapse in Patients with Opioid-Use Disorders (OUD)
    Medical condition: Methadone and buprenorphine comprise a first-line, evidence-based opioid substitution treatment (OST) for OUD patients. Unfortunately, retention and adherence to OST treatment is currently a major ...
    Disease: Version SOC Term Classification Code Term Level
    20.1 10037175 - Psychiatric disorders 10019935 Heroin addiction LLT
    20.1 10037175 - Psychiatric disorders 10030900 Opium addiction LLT
    20.0 10037175 - Psychiatric disorders 10012378 Depression PT
    21.1 10037175 - Psychiatric disorders 10057840 Major depression PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: CY (Trial now transitioned)
    Trial results: (No results available)
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