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Clinical trials for Microcirculation

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    68 result(s) found for: Microcirculation. Displaying page 1 of 4.
    1  2  3  4  Next»
    EudraCT Number: 2012-005651-17 Sponsor Protocol Number: plexusogsirkulasjon Start Date*: 2013-06-13
    Sponsor Name:Oslo Universitetssykehus
    Full Title: Plexus brachialis block and circulation. Comparing effects on skin microcirculation and macro circulation of lidocain brachial plexus block with versus without epinephrine.
    Medical condition: human microcirculation and haemodynamic changes (macrosirculation) in healthy volunteers.
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-004582-14 Sponsor Protocol Number: XENOMICRO Start Date*: 2014-01-28
    Sponsor Name:Department of Anesthesiology and Perioperative Medicine
    Full Title: Haemodynamic effects of xenon or sevoflurane anesthesia on microcirculation
    Medical condition: Patients with ASA III classification (left ventricular failure) undergoing implantation of a defibrillator.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-005685-30 Sponsor Protocol Number: 2015-005685-30 Start Date*: 2016-04-08
    Sponsor Name:Hôpital Erasme
    Full Title: Evaluation of microcirculation alterations in cardiac surgery, by FMD (Flow Mediated vasoDilation), Near Infrared Spectrophotometry (NIRS) and biological analysis
    Medical condition: Cardiac pathology eligible for surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-017789-22 Sponsor Protocol Number: OPHT-080210 Start Date*: 2010-05-19
    Sponsor Name:Ursapharm Arzneimittel GmbH
    Full Title: A randomized, placebo-controlled study investigating the effects of moxaverine on ocular blood flow after oral administration in healthy subjects
    Medical condition: healthy subjects
    Disease: Version SOC Term Classification Code Term Level
    12.1 10038881 Retinal microcirculation disorder LLT
    12.1 10030067 Ocular vascular disorders NEC HLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2013-001743-31 Sponsor Protocol Number: NL43882.029.13 Start Date*: 2013-08-06
    Sponsor Name:VU University Medical Center
    Full Title: The cardiovascular effects of hyperoxia during and shortly after CABG surgery
    Medical condition: During and after coronary artery bypass graft operation we will investigate the cardiovascular effects of hyperoxia on blood pressure, cardiac function, microcirculation and ischemia/reperfusion.
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004866 10051615 Atherosclerotic cardiovascular disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-002834-36 Sponsor Protocol Number: Retro-001 Start Date*: 2012-09-13
    Sponsor Name:UMCG
    Full Title: Evaluation of the effects of the addition of atropine during propofol/remifentanil induction of anesthesia on hemodynamics, microvascular blood flow and tissue oxygenenation in patients undergoing ...
    Medical condition: ophthalmic surgery
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-008367-95 Sponsor Protocol Number: Kalani1 Start Date*: 2009-03-31
    Sponsor Name:Karolinska Institutet, Inst för kliniska vetenskaper, Danderyds sjukhus
    Full Title: Effect of exenatid on microcirculation in patients with type 2 diabetes mellitus and coronary artery disease
    Medical condition: Patients with type 2 diabetes and coronary artery disease.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-000173-39 Sponsor Protocol Number: Kin-Net-2013-33-Ger Start Date*: 2014-12-08
    Sponsor Name:Jan van Breemen Research Institute Reade and VU University Medical Centre
    Full Title: The effect of IL-1 inhibition by anakinra in acute gout - A proof of concept study-
    Medical condition: Gout
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-003958-94 Sponsor Protocol Number: CVAH631BDE06 Start Date*: 2005-12-02
    Sponsor Name:Novartis Phama GmbH
    Full Title: A randomized, open-label, multicenter, cross-over trial to evaluate the efficacy of a 20 week treatment of Valsartan 320 mg (Diovan) versus Atenolol 100 mg in combination with Hydrochlorothiazide o...
    Medical condition: Essential mild-to-moderate hypertension
    Disease: Version SOC Term Classification Code Term Level
    M15 10020772 LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2014-002036-14 Sponsor Protocol Number: V3.10.5.2014 Start Date*: 2014-08-08
    Sponsor Name:Lars Bo Svendsen
    Full Title: The effect of epidural anaesthesia on systemic and splanchnic hemodynamic during gastroesophageal resections, a randomized controlled trial
    Medical condition: The effect of epidural anaesthesia on systemic and splanchnic hemodynamic during gastroesophageal cancer resection
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004864 10066354 Adenocarcinoma of the gastroesophageal junction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2017-000724-10 Sponsor Protocol Number: 60978 Start Date*: 2018-07-04
    Sponsor Name:Academic Medical Center
    Full Title: Targeting esophageal cancer with HDL nanoparticles: an imaging study
    Medical condition: Primary esophageal cancer
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-003621-33 Sponsor Protocol Number: ESR-15-10793 Start Date*: 2016-02-25
    Sponsor Name:Fundación Interhospitalaria de Investigación Cardiovascular
    Full Title: PRotective Effect on the coronary microcirculation of patients with DIabetes by Clopidogrel or Ticagrelor:A randomized multicenter clinical trial using intracoronary multimodal physiology
    Medical condition: Ischemic Heart Disease in Diabetic patients
    Disease: Version SOC Term Classification Code Term Level
    18.1 10007541 - Cardiac disorders 10072685 Microvascular coronary artery disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2013-002189-38 Sponsor Protocol Number: 44945 Start Date*: 2017-10-11
    Sponsor Name:Erasmus Medical Center
    Full Title: OPTIMIZING PERIPHERAL CIRCULATION WITH VASODILATOR THERAPY IN CRITICALLY ILL PATIENTS WITH CIRCULATORY SHOCK: A PILOT STUDY
    Medical condition: Circulatory shock
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-006266-29 Sponsor Protocol Number: 2504/2008 Start Date*: 2008-11-20
    Sponsor Name:AZIENDA OSPEDALIERA PISANA
    Full Title: Optimal Strategy for Coronary Artery Reperfusion
    Medical condition: Acute coronary syndrome ST-elevation patients
    Disease: Version SOC Term Classification Code Term Level
    9.1 10051592 Acute coronary syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-006115-23 Sponsor Protocol Number: BCBe/07/Neb-Space/102 Start Date*: 2008-04-03
    Sponsor Name:Berlin-Chemie AG
    Full Title: Effects of nebivolol on the cardiovascular functions, thermoregulation and blood flow during real and simulated conditions of microgravity
    Medical condition: Effects on the cardiovascular functions, thermoregulation and blood flow during microgravity
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2021-003310-39 Sponsor Protocol Number: 2021_CHUSTP_DAPAMICRO Start Date*: 2021-10-29
    Sponsor Name:CHU Saint Pierre
    Full Title: Effect of the antidiabetic drug DAPAgliflozin on the coronary macrovascular and MICROvascular function in type 2 diabetic patients (DAPAMICRO)
    Medical condition: Coronary macrovascular and microvascular function of type 2 diabetic patients with stable coronary artery disease and acute coronary syndrome (excluding ST elevation myocardial infarction).
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2010-023767-18 Sponsor Protocol Number: TPO 736 Start Date*: 2011-01-17
    Sponsor Name:Medisch Centrum Leeuwarden
    Full Title: Evaluatie van het effect van ketanserin i.v. op de sublinguale microcirculatie middels SDF-imaging bij septische patienten op de Intensive Care
    Medical condition: severe sepsis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-001359-60 Sponsor Protocol Number: Vasobrain01 Start Date*: 2015-06-16
    Sponsor Name:Aarhus University Hospital
    Full Title: Influence of vasopressors on brain oxygenation and microcirculation in anesthetized patients with cerebral tumors
    Medical condition: Brain oxygenation and microcirculation under administration of Efedrin and Metaoxedrin in patients with cerebral tumor.
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004864 10007050 Cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2008-001319-39 Sponsor Protocol Number: 18/2008/U/Sper Start Date*: 2008-04-11
    Sponsor Name:AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI
    Full Title: PROtection of coronary Microcirculation by Iloprost: Safety and Efficacy in Percutaneous Coronary Intervention
    Medical condition: Coronary heart disease with stable angina or non-ST elevation myocardial infarction (NSTEMI)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10051592 Acute coronary syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2019-002821-31 Sponsor Protocol Number: AKST4290-206 Start Date*: 2019-10-10
    Sponsor Name:Alkahest, Inc
    Full Title: The Effect of AKST4290 on Choroidal Blood Flow in Patients with Neovascular Age-Related Macular Degeneration
    Medical condition: Age-related macular degeneration
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004853 10075568 Wet age-related macular degeneration LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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