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Clinical trials for Modulation

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    252 result(s) found for: Modulation. Displaying page 1 of 13.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2013-002143-29 Sponsor Protocol Number: 10378/13 Start Date*: 2013-08-03
    Sponsor Name:POLICLINICO GEMELLI
    Full Title: Pharmacological modulation of inflammation and platelet activation in inflammatory bowel diseases
    Medical condition:
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2014-002481-78 Sponsor Protocol Number: EBI-EA230-LPS-2014 Start Date*: 2014-10-07
    Sponsor Name:Exponential Biotherapies Inc
    Full Title: Randomized double blind placebo-controlled clinical safety, tolerability and pharmacokinetic/-dynamic study on the effects of escalating single intravenous doses of EA-230 on the innate immune resp...
    Medical condition: Systemic inflammatory respons (SIRS) and associated acute kidney injury (AKI)
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2011-006302-28 Sponsor Protocol Number: OXYGENE Start Date*: 2012-07-11
    Sponsor Name:UNIVERSITA' DEGLI STUDI DI PARMA
    Full Title: Dopamine modulation of oxytocin prosocial effects
    Medical condition: HEALTHY VOLUNTEERS. FOR PATIENTS WITH AUTISM OR SCHIZOPHRENIA
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2015-005383-42 Sponsor Protocol Number: BREATH Start Date*: 2016-05-19
    Sponsor Name:FONDAZIONE TOSCANA GABRIELE MONASTERIO
    Full Title: Use of buspiron in chemioreflex modulation and central apnea treatment in heart failure patients (BREATH: BuspiRon for chEmoreflex modulation and central Apnea treatment in Heart failure patients)....
    Medical condition: patient with central apneas syndrome and heart failure
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10011949 Decompensation cardiac LLT
    20.0 100000004852 10040978 Sleep apnoeas HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2020-001285-11 Sponsor Protocol Number: P20.XXX Start Date*: 2021-01-12
    Sponsor Name:Leiden University Medical Center
    Full Title: A Randomized, open label, Non-inferiority trial on the efficacy of Lacosamide versus Duloxetine in Patients with Chemotherapy-induced Polyneuropathy – A strategy trial
    Medical condition: Chemotherapy-induced polyneuropathy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2014-005701-20 Sponsor Protocol Number: ANST2015_1 Start Date*: 2015-05-20
    Sponsor Name:Leiden University Medical Center
    Full Title: Shifting pain modulation towards anti-nociceptivity: Mechanism-specific pharmacological prevention of post sternotomy pain: the MASTER study
    Medical condition: chronic pain
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-003574-26 Sponsor Protocol Number: ucihsjd5 Start Date*: 2008-04-09
    Sponsor Name:Hospital Sant Joan de Deu
    Full Title: MODULACIÓN DE LA RESPUESTA INFLAMATORIA SISTÉMICA EN NIÑOS CRÍTICAMENTE ENFERMOS TRAS LA SUPLEMENTACIÓN CON GLUTAMINA MODULATION OF THE SYSTEMIC INFLAMMATORY RESPONSE IN CRITICAL ILL CHILDREN AFTE...
    Medical condition: MODULACIÓN DE LA RESPUESTA INFLAMATORIA SISTÉMICA EN NIÑOS CRÍTICAMENTE ENFERMOS TRAS LA SUPLEMENTACIÓN CON GLUTAMINA MODULATION OF THE SYSTEMIC INFLAMMATORY RESPONSE IN CRITICAL ILL CHILDREN AFTE...
    Disease:
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-000434-21 Sponsor Protocol Number: LP1 Start Date*: 2005-06-15
    Sponsor Name:Kognitive Neurologie, Institut für Medizin, Forschungszentrum Jülich
    Full Title: Neurochemische Modulation von Exekutiv- und Gedächtnisfunktionen
    Medical condition: Progressive cognitive decline in physiological aging
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-004208-37 Sponsor Protocol Number: S63190 Start Date*: 2020-08-03
    Sponsor Name:UZ Leuven
    Full Title: Drug repurposing - Statins as microbiota modulating agents in ulcerative colitis
    Medical condition: There are two population groups, 20 healthy volunteers and at least 165 individuals diagnosed with IBD. Either with remission to mild/moderate active ulcerative colitis or remission to mild Crohn's...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2013-001212-30 Sponsor Protocol Number: GW/MB/42964 Start Date*: 2013-07-04
    Sponsor Name:
    Full Title: Modulation of immune function by parenteral fish oil in patients with Crohn’s disease and high inherent Tumor Necrosis Factor-alfa production, a randomized, single blinded, cross-over study
    Medical condition: Crohn's disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-003617-33 Sponsor Protocol Number: 03-2005 Start Date*: Information not available in EudraCT
    Sponsor Name:Charité
    Full Title: A Randomised Cross-Over Study to Explore the Pathophysiological Mechanisms Involved in the Treatment of Actinic Keratoses with Solaraze
    Medical condition: actinic keratosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-004372-39 Sponsor Protocol Number: SKS-HIV-002 Start Date*: 2007-11-05
    Sponsor Name:Department of Infectious Diseases, Aarhus University Hospital, Skejby
    Full Title: Effect and safety of switching from zidovudin to either tenofovir or abacavir in patients suffering from HIV. An open label study.
    Medical condition: HIV
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2010-023044-32 Sponsor Protocol Number: DCS-fMRIPanik Start Date*: 2011-08-10
    Sponsor Name:Charité Universitaetsmedizin Berlin
    Full Title: Mechanisms of action in exposure therapy: Decoding the neural basis of fear extinction and its pharmacological modulation in patients with panic disorder
    Medical condition: panic disorder and agoraphobia
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2004-004066-32 Sponsor Protocol Number: OB/ERYTH 2004-004066-32 Start Date*: 2006-02-01
    Sponsor Name:Silvia Delgado Aros
    Full Title: Reducción de la Ingesta Calórica en la Obesidad Mediante Modulación Farmacológica del Vaciamiento Gástrico Reduction of Caloric Intake in Obesity through Pharmacological Modulation of Gastric Empt...
    Medical condition: Obesidad/Sobrepeso Obesity/Overweight
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2011-000397-59 Sponsor Protocol Number: none Start Date*: 2011-03-21
    Sponsor Name:
    Full Title: Prevention of post-ERCP acute pancreatitis by heme-oxygenase activation through the administration of hemin: a prospective, randomized double blind controlled trial.
    Medical condition: Prevention of post-ERCP acute pancreatitis. So, patient with indications of ERCP (endoscopic retrograde cholangiopanreatography) will be included. These patients suffer from bilio-pancreatic disord...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-000024-34 Sponsor Protocol Number: CH-MAX-FACC-TR-12 Start Date*: 2015-01-13
    Sponsor Name:AOU di Bologna, Policlinico S.Orsola-Malpighi
    Full Title: Use of PRP from umbilical cord in post-extractive sites
    Medical condition: • Patients who require extraction of dental elements and subsequent implant rehabilitation in the same site.
    Disease: Version SOC Term Classification Code Term Level
    17.0 10028395 - Musculoskeletal and connective tissue disorders 10068975 Bone atrophy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-001970-28 Sponsor Protocol Number: CMV-001 Start Date*: 2012-11-20
    Sponsor Name:University of Birmingham
    Full Title: Does CMV reactivation cause functional impairment of CMV specific CD4+ T-cells? The potential for valaciclovir to prevent CMV-mediated adverse modulation of the immune system in patients with ANCA-...
    Medical condition: This study will investigate the modulation of the immune system by Cytomegalovirus (CMV) in ANCA-associated vasculitis. Specifically the study will investigate the potential for valaciclovir to ...
    Disease: Version SOC Term Classification Code Term Level
    15.0 10021881 - Infections and infestations 10011831 Cytomegalovirus infection PT
    15.0 10021428 - Immune system disorders 10050894 Anti-neutrophil cytoplasmic antibody positive vasculitis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2005-000408-16 Sponsor Protocol Number: HS-PM-013 Start Date*: 2005-04-05
    Sponsor Name:Karolinska University Hospital, Huddinge
    Full Title: Caffeine-mediated modulation of human experimental pain models
    Medical condition: Healthy human volunteer subjects
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-003822-80 Sponsor Protocol Number: 04/035 Start Date*: 2005-01-12
    Sponsor Name:The Leeds Teaching Hospitals NHS Trust
    Full Title: Modulation of Sympathetic Nerve Activity By Pioglitazone In Type 2 Diabetes Mellitus
    Medical condition: Type 2 diabetes mellitus
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2008-006776-29 Sponsor Protocol Number: 081016 Start Date*: 2009-02-18
    Sponsor Name:Karolinska Institutet
    Full Title: NO som behandling vid knäproteskirurgi. Studie med avseende på anti-inflammatorisk modulation hos patienter som genomgår operation med ryggbedövning.
    Medical condition: Patienter som skall genomgå knäprotesoperation och skall ha bedövning i form av ryggbedövning (spinalanestes/epiduralanestesi).
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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