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Clinical trials for Motilin

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44336   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    7 result(s) found for: Motilin. Displaying page 1 of 1.
    EudraCT Number: 2020-004442-11 Sponsor Protocol Number: JAZ-01 Start Date*: 2020-12-01
    Sponsor Name:Zealand University Hospital
    Full Title: The effect of Melatonin in patients with Low Anterior Resection Syndrome
    Medical condition: Low anterior resection syndrome
    Disease: Version SOC Term Classification Code Term Level
    20.1 10022117 - Injury, poisoning and procedural complications 10080023 Low anterior resection syndrome PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-004332-29 Sponsor Protocol Number: food_intake Start Date*: 2013-12-18
    Sponsor Name:UZLeuven
    Full Title: The influence of erythromycin and bitter administration on ad libitum food intake in healthy volunteers and patients
    Medical condition: The effect of erythromycin administration on voluntary food intake will be tested in healthy volunteers, obese patients and patients with unexplained weight loss
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2013-004411-53 Sponsor Protocol Number: Erythromycin_v5 Start Date*: 2014-05-15
    Sponsor Name:University of Leuven
    Full Title: Brain mechanisms underlying the effect of the motilin receptor agonist erythromycin on hunger in normal weight subjects
    Medical condition: The effect of erythromycin administration on hunger and brain responses will be tested in healthy volunteers
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2012-004600-35 Sponsor Protocol Number: Modifast3 Start Date*: 2012-12-19
    Sponsor Name:KULeuven
    Full Title: Effect of diet-induced weight loss on motilin, ghrelin, bitter taste perception, hunger and the migrating motor complex: a prospective study
    Medical condition: Gastrointestinal contractility and hormones will be studied in obese patients before and after weight loss induced by a diet
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-004438-32 Sponsor Protocol Number: MOT115816 Start Date*: 2012-04-25
    Sponsor Name:GlaxoSmithKline Research and Development Limited
    Full Title: A randomized, double-blind, placebo-controlled, parallel group, dose ranging study to assess the effect of repeat doses of GSK962040 on the pharmacokinetics of levodopa in subjects with Parkinson’s...
    Medical condition: Investigate the ability of the motilin receptor agonist GSK962040 to improve levodopa pharmacokinetics (PK) by enhancing GE via motilin receptor agonism.
    Disease: Version SOC Term Classification Code Term Level
    20.1 10017947 - Gastrointestinal disorders 10051153 Diabetic gastroparesis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) SE (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2010-023186-21 Sponsor Protocol Number: MOT114479 Start Date*: 2011-06-28
    Sponsor Name:GlaxoSmithKline Research and Development Ltd
    Full Title: A Randomized, Double-Blind, Placebo-Controlled Multicenter Phase II Study to Evaluate the Safety and Efficacy and Dose Response of 28 Days of Once-Daily Dosing of the Oral Motilin Receptor Agonist ...
    Medical condition: Diabetic gastroparesis
    Disease: Version SOC Term Classification Code Term Level
    14.1 10017947 - Gastrointestinal disorders 10051153 Diabetic gastroparesis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) SE (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-008175-34 Sponsor Protocol Number: MOT111809 Start Date*: 2009-03-31
    Sponsor Name:GlaxoSmithKline Research & Development Ltd
    Full Title: A Multicenter, Double-Blind, Randomized Placebo-Controlled Phase II Study to Evaluate the Pharmacodynamics, Safety, Tolerability, and Pharmacokinetics of Single Doses of the Oral Motilin Receptor A...
    Medical condition: Diabetic Gastroparesis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10051153 Diabetic gastroparesis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) SE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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