interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development
EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
Clinical Trials Information System (CTIS).
The EU Clinical Trials Register currently displays
44334
clinical trials with a EudraCT protocol, of which
7366
are clinical trials conducted with subjects less than 18 years old.
The register also displays information on
18700
older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).
Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see
Frequently Asked Questions ).
2 result(s) found for: Multiple endocrine neoplasia type 2B.
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EudraCT Number: 2022-002173-28
Sponsor Protocol Number: C4391002
Start Date*: 2023-01-25
Sponsor Name:Pfizer Inc.
Full Title: PHASE 1B/2, OPEN-LABEL, MULTICENTER, DOSE ESCALATION AND DOSE EXPANSION STUDY TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, PHARMACODYNAMICS, AND ANTITUMOR ACTIVITY OF PF-07220060 IN COMB...
Medical condition: HR-positive HER2-negative metastatic/advanced BC
Disease:
Version
SOC Term
Classification Code
Term
Level
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10006187
Breast cancer
PT
20.1
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10055113
Breast cancer metastatic
PT
Population Age: Adults, Elderly
Gender: Male, Female
Trial protocol:BG(Trial now transitioned)CZ(Trial now transitioned)ES(Ongoing)
Trial results:(No results available)
EudraCT Number: 2022-001679-15
Sponsor Protocol Number: C4161001
Start Date*: 2022-09-30
Sponsor Name:Pfizer Inc.
Full Title: PHASE 1/2A DOSE ESCALATION, FINDING AND EXPANSION STUDY EVALUATING SAFETY, TOLERABILITY, PHARMACOKINETICS, PHARMACODYNAMICS AND ANTI TUMOR ACTIVITY OF PF-07104091 AS A SINGLE AGENT AND IN COMBINATI...
Medical condition: HR+ HER2- Metastatic Breast Cancer, Ovarian Cancer, Small Cell Lung Cancer (Part 1 also had Triple Negative BC and Non Small Cell Lung Cancer)
Disease:
Version
SOC Term
Classification Code
Term
Level
21.1
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10072737
Advanced breast cancer
LLT
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10033128
Ovarian cancer
PT
21.1
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
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