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Clinical trials for Nasal decongestant

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44339   clinical trials with a EudraCT protocol, of which   7369   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    10 result(s) found for: Nasal decongestant. Displaying page 1 of 1.
    EudraCT Number: 2019-003254-91 Sponsor Protocol Number: AGO/2019/005 Start Date*: 2020-08-18
    Sponsor Name:Ghent University Hospital
    Full Title: Characterisation and intervention study in patients with long-term use of nasal decongestants.
    Medical condition: rhinitis medicamentosa
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Trial now transitioned)
    Trial results: View results
    EudraCT Number: 2005-004309-27 Sponsor Protocol Number: P04579 Start Date*: 2005-12-28
    Sponsor Name:Schering Plough Research Institute
    Full Title: Cross-Over Study of the Decongestant Effect of Phenylephrine Compared With Placebo and Pseudoephedrine as Active Control in SAR Subjects Exposed to Pollen in the Vienna Challenge Chamber
    Medical condition: Seasonal Allergic Rhinitis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2011-002443-10 Sponsor Protocol Number: 2011035 Start Date*: 2011-06-23
    Sponsor Name:Procter & Gamble Technical Centres Ltd., UK
    Full Title: A Randomized, Open-Label, Single-Dose, Parallel Group Study to Evaluate the Utility of Magnetic Resonance Imaging (MRI) in Demonstrating the Nasal Decongestant Efficacy of an Active Control (Vicks®...
    Medical condition: Nasal Congestion due to the common cold or hay fever
    Disease: Version SOC Term Classification Code Term Level
    13.1 10038738 - Respiratory, thoracic and mediastinal disorders 10028735 Nasal congestion PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2015-002796-23 Sponsor Protocol Number: RHINO-CZ-2015-01 Start Date*: 2015-09-10
    Sponsor Name:Laboratoire de la Mer
    Full Title: Multicenter, parallel, randomized, single-blind trial comparing the efficacy and tolerability of Rhinaction®, an osmotic decongestant nasal spray containing essential oils versus Olynth® 0.1%, a va...
    Medical condition: Acute rhinitis Adults aged ≥18years old suffering from acute rhinitis with symptoms present for up to 72h. The purpose of this study is to demonstrate the efficacy and compare safety and tolerab...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-003194-82 Sponsor Protocol Number: VAI03 Start Date*: 2007-09-05
    Sponsor Name:University of Dundee
    Full Title: A proof of concept study to evaluate differential tachyphylaxis of α1 and α2 adrenoreceptor mediated decongestant response to oxymetazoline and its acute reversal by corticosteroid in healthy volun...
    Medical condition: This is a proof of concept trial on Healthy Volunteers to evaluate the tolerance of nasal adrenoreceptors to prolonged decongestant use and upregulation by intranasal steroids. The medical conditio...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10043087 Tachyphylaxis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2019-004936-52 Sponsor Protocol Number: CASK0119 Start Date*: 2020-04-17
    Sponsor Name:Cassella-med GmbH & Co KG
    Full Title: Prospective, controlled, randomized double-blind study to determine the sensory perception of two nasal sprays using the model of treatment of post-operative complaints after surgery on the nasal m...
    Medical condition: Post-operative nasal blockage following surgical interventions of the nasal cavity.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-006690-25 Sponsor Protocol Number: OTCS-CE-301 Start Date*: 2007-02-09
    Sponsor Name:Novartis Consumer Health SA
    Full Title: A Double-Blind, Randomized, Parallel Group, Placebo Controlled Study, Evaluating the Decongestant Effect, Time to Onset, Duration of Effect and Impact on Sleep and General Well-being of Otrivin F2 ...
    Medical condition: nasal congestion associated with the common cold
    Disease: Version SOC Term Classification Code Term Level
    9.1 10010106 Common cold LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-001883-39 Sponsor Protocol Number: P02561 Start Date*: 2004-09-21
    Sponsor Name:Schering Plough Reserach Institute
    Full Title: Study to Evaluate the Effect of the Coadministration of SCH 497079 (a Histamine 3 [H3] Receptor Antagonist) Plus Desloratadine on Nasal Congestion in Subjects With Seasonal Allergic Rhinitis Who Ha...
    Medical condition: Seasonal Allergic Rhinitis
    Disease: Version SOC Term Classification Code Term Level
    7.0 10039776 LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2018-004621-89 Sponsor Protocol Number: LYR-210-2018-002 Start Date*: 2019-07-29
    Sponsor Name:Lyra Therapeutics, Inc.
    Full Title: A Phase II, Randomized, Blinded, Sham Procedure-Controlled, Parallel-Group Trial to Evaluate the Efficacy, Safety and Tolerability of LYR-210 in Adult Subjects with Chronic Sinusitis (LANTERN Study)
    Medical condition: Chronic sinusitis
    Disease: Version SOC Term Classification Code Term Level
    20.1 10021881 - Infections and infestations 10009137 Chronic sinusitis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) AT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-000260-24 Sponsor Protocol Number: NAC600-ZI-L-01-06 Start Date*: 2007-05-21
    Sponsor Name:ZAMBON ITALIA
    Full Title: EVALUATION OF THE CLINICAL AND MICROBIOLOGICAL EFFICACY OF N-ACETILCISTEINA 600 MG, IN COMBINATION TO CEFPODOXIMA PROXETILE, IN THE THERAPY OF THE INFECTIONS OF THE HIGH RESPIRATORY WAYS IN ADULT P...
    Medical condition: Infection of the high respiratory ways in adult patients
    Disease: Version SOC Term Classification Code Term Level
    9.1 10004054 Bacterial upper respiratory tract infections HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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