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Clinical trials for Neostigmine

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    36 result(s) found for: Neostigmine. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2014-002021-35 Sponsor Protocol Number: ANR-1/14 Start Date*: 2014-09-23
    Sponsor Name:Fondazione IRCCS Istituto Nazionale dei Tumori
    Full Title: Decurarization After Thoracic Anesthesia - A prospective multicenter double-blind randomized trial comparing sugammadex vs neostigmine reversal after thoracic anesthesia
    Medical condition: Neuromuscular block is commonly adopted during general anesthesia to facilitate tracheal intubation, mechanical ventilation and surgical manipulation. At the end of anesthesia it very important to ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-002528-10 Sponsor Protocol Number: SIVAA01 Start Date*: 2017-07-06
    Sponsor Name:Vestfold Hospital Trust
    Full Title: TOF trial: A randomized double blinded controlled Trial comparing low dose Of sugammadex and neostigmine aFter use of rocuronium during general anesthesia in patients undergoing non-cardiac surgery
    Medical condition: The study population will include all patients >18 years scheduled for an elective surgical procedure undergoing general anesthesia with intravenous drugs and non-depolarizing NMBA (rocuronium), wi...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2019-002187-26 Sponsor Protocol Number: neostigmine2019 Start Date*: 2019-08-28
    Sponsor Name:KU Leuven - TARGID
    Full Title: A Prospective evaluation of the effect of a single dose of neostigmine in patients with patients with weak or absent esophageal peristalsis
    Medical condition: Patients with complaints of dysphagia and poor esophageal motility
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2007-005512-12 Sponsor Protocol Number: MVDV Start Date*: 2007-12-19
    Sponsor Name:University Hospitals Leuven
    Full Title: Een verbetering van de analgesie na episiotomie door epidurale toediening van neostigmine en clonidine.
    Medical condition: Combinedn spinal-epidural analgesia during labour.
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2019-000561-20 Sponsor Protocol Number: 020186 Start Date*: 2020-02-28
    Sponsor Name:Tampere University Hospital
    Full Title: Monitoring of neuromuscular blockade during general anaesthesia after reversal with neostigmine
    Medical condition: We are studying reappearence of nondepolarizing neuromuscular block after it has been antagonized with a combination of neostigmine and glycopyrrolate. We are trying to find the incidence of the ph...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2013-002078-30 Sponsor Protocol Number: REDNES06052013 Start Date*: 2013-08-08
    Sponsor Name:Onze-Lieve-Vrouw Ziekenhuis
    Full Title: Acceleromyography and diaphragm electromyographic activity during neostigmine or sugammadex enhanced recovery from moderate residual neuromuscular blockade after rocuronium 0.6 mg kg-1: a double bl...
    Medical condition: We will compare usual care (neostigmine) with sugammadex for reversal of a moderate rocuronium-induced neuromuscular blockade and assess the effect on diaphragmatic EMG activity of sugammadex versu...
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-001135-30 Sponsor Protocol Number: 19.4.301 Start Date*: 2005-10-18
    Sponsor Name:NV Organon
    Full Title: A multi-center, randomized, parallel group, comparative, active controlled, safety-assessor blinded, phase IIIa, pivotal trial, in adult subjects comparing Org 25969 with neostigmine as reversal ag...
    Medical condition: Not applicable
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) SE (Completed) GB (Completed) ES (Completed) IT (Completed) BE (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2014-005116-41 Sponsor Protocol Number: AOP0071 Start Date*: 2015-06-24
    Sponsor Name:University of Padova
    Full Title: Postoperative pulmonary function in patients undergoing laparoscopic sleeve gastrectomy after administration of sugammadex and neostigmine. A double-blind, randomized controlled trial.
    Medical condition: Reversal of rocuronium-induced neuromuscular blockade
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-005845-12 Sponsor Protocol Number: 11/2006 - MVdV Start Date*: 2007-01-08
    Sponsor Name:UZ leuven, Marc Van de Velde
    Full Title: Combined spinal-epidural anaesthesia during labour : has the epidural administration of clonidine and neostigmine a positive influence on the quality of analgesia ?
    Medical condition: combined spinal-epidural analgesia during labour
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2008-008434-36 Sponsor Protocol Number: VDV12/08 Start Date*: 2009-02-12
    Sponsor Name:Marc Van de Velde
    Full Title: Een gecombineerde spinale epidurale anesthesie bij arbeid : positieve invloed op kwaliteit van analgesie door epiduraal clonidine en neostigmine bij doorbraakpijn?
    Medical condition: Combined spinal-epidural analgesia during labour
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2008-008239-27 Sponsor Protocol Number: SUNDRO Start Date*: 2009-02-13
    Sponsor Name:Technische Universität München
    Full Title: Dosisfindungsstudie Sugammadex und Neostigmin bei geringer neuromuskulärer Restblockade (Sugammadex and Neostigmine dose finding study for reversal of residual neuromuscular blockade)
    Medical condition: Dose finding study for sugammadex and/or neostigmine at residual neuromuscular blockade (whereas residual neuromuscular blockade is defined as a TOF of 0.5 in this study).
    Disease: Version SOC Term Classification Code Term Level
    9.1 10057286 Neuromuscular blockade reversal LLT
    9.1 10057286 Neuromuscular blockade reversal PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-013499-29 Sponsor Protocol Number: SUNDRO20 Start Date*: Information not available in EudraCT
    Sponsor Name:Technische Universität München
    Full Title: Dosisfindungsstudie für Sugammadex und Neostigmin zur Reversierung einer geringen neuromuskulären Restblockade (train of four ratio 0,2) [Sugammadex and Neostigmine dose finding study for reversal ...
    Medical condition: Dose finding study for sugammadex and/or neostigmine at residual neuromuscular blockade (whereas residual neuromuscular blockade is defined as a TOF of 0.2 in this study).
    Disease: Version SOC Term Classification Code Term Level
    9.1 10057286 Neuromuscular blockade reversal LLT
    9.1 10057286 Neuromuscular blockade reversal PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-001792-35 Sponsor Protocol Number: 19.4.310 Start Date*: 2005-09-28
    Sponsor Name:NV Organon
    Full Title: Comparison of rocuronium and Org 25969 with cis-atracurium and neostigmine when neuromuscular block is reversed at reappearance of T2
    Medical condition: Not applicable
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2014-005156-26 Sponsor Protocol Number: PRIN-SUGAR-2014 Start Date*: 2015-05-27
    Sponsor Name:Dr. Enrique Alday
    Full Title: Effects of neuromuscular block reversal with sugammadex vs neostigmine on postoperative respiratory outcomes after major abdominal surgery. A randomized controlled trial.
    Medical condition: Patients of both sexes proposed for major abdominal surgery under general anesthesia plus epidural
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-007951-14 Sponsor Protocol Number: 19.4.318 Start Date*: 2008-05-05
    Sponsor Name:NV Organon
    Full Title: A multi-center, randomized, parallel-group, comparative, active-controlled, safety-assessor blinded trial in adult subjects comparing the efficacy and safety of sugammadex administered at 1-2 PTC w...
    Medical condition: Not applicable
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) GB (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-006304-37 Sponsor Protocol Number: 19.4.324 Start Date*: 2008-03-19
    Sponsor Name:NV Organon
    Full Title: A multi-center, randomized, parallel-group, active-controlled, safety-assessor blinded trial, comparing the efficacy and safety of 2.0 mg.kg-1 sugammadex with 50 μg.kg-1 neostigmine administered at...
    Medical condition: Not applicable
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2011-000401-50 Sponsor Protocol Number: CT-PED-2010-01 Start Date*: 2011-08-09
    Sponsor Name:Fundación para la Formación e Investigación Sanitarias de la Región de Murcia
    Full Title: Efficacy and safety of reversal with Sugammadex (BRIDION®) from deep Neuromuscular Blockade induced by rocuronium in children
    Medical condition: Neuromuscular Blockade induced by Rocuronium
    Disease: Version SOC Term Classification Code Term Level
    14.0 10042613 - Surgical and medical procedures 10057286 Neuromuscular blockade reversal PT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-004666-34 Sponsor Protocol Number: AITT2014/1 Start Date*: 2014-03-17
    Sponsor Name:University of Debrecen, Medical and Health Science Center, Department of Anaesthesiology and Intensive Therapy
    Full Title: Reversal of vecuronium induced residual neuromuscular block using sugammadex: a prospective, dobule-blind, randomized, controlled, dosefinding study
    Medical condition: The effect of sugammadex dose on residual neuromuscular blockade will be investigated, therefore patients suffering from various conditions undergoing surgery in general anaesthesia with muscle rel...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-005222-19 Sponsor Protocol Number: BREATH Start Date*: 2016-07-14
    Sponsor Name:Leiden University Medical Center
    Full Title: Effect of neuromuscular blockade and reversal by sugammadex versus neostigmine on breathing when hypoxic or hypercapnic in volunteers
    Medical condition: Postoperative ventilatory control
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004855 10038680 Respiratory depression postoper LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-000692-92 Sponsor Protocol Number: MK-8616-089 Start Date*: 2019-02-01
    Sponsor Name:Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.
    Full Title: A Phase 4 Double-Blinded, Randomized, Active Comparator-Controlled Clinical Trial to Study the Efficacy, Safety, and Pharmacokinetics of Sugammadex (MK-8616) for Reversal of Neuromuscular Blockade ...
    Medical condition: Reversal of neuromuscular blockade (NMB)
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004865 10018061 General anesthesia LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: AT (Completed) ES (Completed) FI (Completed) BE (Completed) DK (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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