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Clinical trials for Orthodontic Treatment

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44394   clinical trials with a EudraCT protocol, of which   7406   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    7 result(s) found for: Orthodontic Treatment. Displaying page 1 of 1.
    EudraCT Number: 2008-005522-36 Sponsor Protocol Number: RD1 Start Date*: 2009-04-03
    Sponsor Name:RUH (Bath) NHS Trust
    Full Title: Chewing gum and orthodontic pain relief
    Medical condition: One of the most frequent side effects of orthodontic treatment with fixed braces is pain. This usually begins 2 to 3 hours after the fitting or adjustment of orthodontic appliances and may last up ...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10050879 Orthodontic appliance wearer LLT
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2005-005184-29 Sponsor Protocol Number: P305-R-EG04 Start Date*: 2006-02-21
    Sponsor Name:GABA GmbH
    Full Title: Prevention of incipient carious lesions (white spot lesions) in patients with fixed orthodontic appliances following the application of elmex® gelée
    Medical condition: incipient carious lesions (white spot lesions)
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2010-020538-24 Sponsor Protocol Number: GASAS-1002X Start Date*: 2011-02-16
    Sponsor Name:GABA International AG
    Full Title: White spot lesion development in post-orthodontic patients following weekly application of a 1.25% fluoride gel compared to placebo over 6 months
    Medical condition: To monitor the white spot lesion development and dental status under weekly applied 1.25% fluoride gel compared to placebo in patients after orthodontic treatment with multibracket appliances
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-000254-13 Sponsor Protocol Number: RD/613/07 Start Date*: 2008-10-14
    Sponsor Name:Gwent Healthcare NHS Trust
    Full Title: A double blind randomised placebo controlled study assessing the effect of intra-operative local anaesthetic administration on postoperative pain in adolescent children undergoing oral surgery unde...
    Medical condition: Postoperative pain following oral surgery in 12 to 16 year olds
    Disease: Version SOC Term Classification Code Term Level
    9.1 10024759 Local anaesthetic LLT
    9.1 10054711 Postoperative pain LLT
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-003548-22 Sponsor Protocol Number: LAEBBA0005 Start Date*: 2014-03-03
    Sponsor Name:Johnson & Johnson Consumer & Personal Products Worldwide, Division of Johnson & Johnson Consumer Companies, Inc
    Full Title: Four Week Clinical Efficacy of An Ethyl Lauroyl Arginate HCL (LAE) Mouth Rinse: Effect on Gingivitis
    Medical condition: Gingivitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2015-004306-42 Sponsor Protocol Number: 2016-1 Start Date*: 2016-01-27
    Sponsor Name:Stomatološka klinika UKC, Ljubljana
    Full Title: Comparison of the efficacy of treatment of chronic periodontitis with scaling and root-planning alone or in combination with azithromycin - a prospective, double blind, randomised clinical trial
    Medical condition: Number of remaining deep pockets after treatment of patients with chornic periodontitis
    Disease: Version SOC Term Classification Code Term Level
    18.1 10021881 - Infections and infestations 10060945 Bacterial infection PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: SI (Completed)
    Trial results: View results
    EudraCT Number: 2012-000260-17 Sponsor Protocol Number: Intermed_Chlorhexidine_sol_0.2%_ Start Date*: 2012-09-07
    Sponsor Name:IOULIA & IRENE TSETI PHARMACEUTICAL LABORATORIES S.A.-INTERMED S.A.
    Full Title: A therapeutic equivalence study, comparing two chlorhexidine digluconate formulations, the test formulation Chlorel® Or. T. Sol. 0,2% w / v and the reference formulation Corsodyl® 0.2% w / v Mint M...
    Medical condition: Therapeutic equivalence study, comparing two chlorhexidine digluconate formulations indicated for inhibition of the formation of dental plaque, as an aid in the treatment and prevention of gingivi...
    Disease: Version SOC Term Classification Code Term Level
    15.0 10042613 - Surgical and medical procedures 10063390 Oral hygiene LLT
    15.0 10017947 - Gastrointestinal disorders 10058078 Tooth plaque LLT
    15.0 10021881 - Infections and infestations 10018294 Gingivitis infection LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GR (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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