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Clinical trials for Pain

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   43871   clinical trials with a EudraCT protocol, of which   7290   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    5,431 result(s) found for: Pain. Displaying page 1 of 272.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2008-003596-46 Sponsor Protocol Number: 942/08 Start Date*: 2009-02-25
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: Multicenter, not-for-profit clinical study, in a open, controlled, randomized fashion to compare tolerability, safety and efficacy of two different treatment strategies for non malignant, persisten...
    Medical condition: non neoplastic cronic pain
    Disease: Version SOC Term Classification Code Term Level
    9.1 10033371 Pain PT
    9.1 10050819 Musculoskeletal chest pain PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2015-002972-26 Sponsor Protocol Number: LDN_7323 Start Date*: 2015-12-14
    Sponsor Name:Smerteklinikken
    Full Title: Low dose naltrexone for treatment of pain in patients with fibromyalgia - effect via central mechanism? A randomized, double-blinded, placebo-controlled, cross-over study
    Medical condition: Pain in patients with fibromylagia
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004867 10049475 Chronic pain LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2010-022794-34 Sponsor Protocol Number: 862-P-201 Start Date*: 2011-03-04
    Sponsor Name:Novartis Consumer Health
    Full Title: A randomized, double-blind, placebo-controlled, multi-center parallel group phase IV study to evaluate the efficacy and safety of Voltaren® Schmerzgel 1.16% gel in subjects with acute neck pain
    Medical condition: Acute neck pain, present for at least 12 hours. An acute condition is defined as pain shorter than 3 months [CPMP, 2002]. Neck pain is defined as stiffness and/or pain felt dorsally in the cervical...
    Disease: Version SOC Term Classification Code Term Level
    13.1 10028395 - Musculoskeletal and connective tissue disorders 10028836 Neck pain PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-005275-33 Sponsor Protocol Number: NL092007 Start Date*: 2009-08-25
    Sponsor Name:
    Full Title: Postoperative analgesia with continuous epidural bupivacaine/sufentanil versus bupivacaine/morphine in patients scheduled for major surgery.
    Medical condition: Pain scores and side-effects of the epidural analgesia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10033371 Pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-001833-16 Sponsor Protocol Number: PROTOCOLLO NPDEP0106 Start Date*: 2006-07-13
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: Multicentric, no-profit, open, controlled randomized clinical study to evaluate comparable tolerability and efficacy of two pharmacological treatments for persistent, non oncological pain in the el...
    Medical condition: persistent non oncological pain
    Disease: Version SOC Term Classification Code Term Level
    10033371 PT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-015589-74 Sponsor Protocol Number: NYC-IBU-1 Start Date*: 2009-10-02
    Sponsor Name:Nycomed Sweden Holding 2 AB
    Full Title: A controlled, randomized, double-blind, cross-over study of the onset of analgesic effect of two formulations of ibuprofen for the treatment of pain after oral surgery.
    Medical condition: Pain
    Disease: Version SOC Term Classification Code Term Level
    12.0 10033371 Pain LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2015-000751-25 Sponsor Protocol Number: AXS02II201501 Start Date*: 2016-05-02
    Sponsor Name:Jaro Karppinen
    Full Title: ZOLEDRONIC ACID, A LONG-ACTING BISPHOSPHONATE, FOR CHRONIC LOW BACK PAIN DUE TO MODIC CHANGES: A RANDOMIZED CONTROLLED TRIAL
    Medical condition: Chronic low back pain
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004859 10024891 Low back pain LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-002215-42 Sponsor Protocol Number: 22/13 Start Date*: Information not available in EudraCT
    Sponsor Name:IRCCS Burlo Garofolo
    Full Title: Single-blind randomized controlled trial for acute abdomen analgesia in Pediatric Emergency department
    Medical condition: Analgesia in pediatric acute abdominal pain
    Disease: Version SOC Term Classification Code Term Level
    17.0 10017947 - Gastrointestinal disorders 10000081 Abdominal pain PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-004517-24 Sponsor Protocol Number: Remi-Pain-01 Start Date*: 2016-05-17
    Sponsor Name:Wilhelminen hospital
    Full Title: A prospective, open-label, proof-of-concept pilot study of the effects of a single one-hour target-controlled remifentanil infusion on pain in 24 patients with persistent postsurgical pain.
    Medical condition: Persistent postsurgical pain/Chronic postoperative pain
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-020547-13 Sponsor Protocol Number: 201001 Start Date*: 2011-08-24
    Sponsor Name:Foot and Ankle Surgical center
    Full Title: A randomized study comparing etoricoxib and diclofenac sodium in post hallux valgus surgery pain
    Medical condition: Postoperative pain
    Disease: Version SOC Term Classification Code Term Level
    12.1 10056350 Pain management PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-000160-25 Sponsor Protocol Number: 14042006 Start Date*: 2007-01-29
    Sponsor Name:University of Kuopio
    Full Title: Tramadolin plasmapitoisuus lääkettä säännöllisesti käyttävillä potilailla
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    9.1 10033371 Pain LLT
    Population Age: Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-003110-40 Sponsor Protocol Number: LACOSAMIDE-2018 Start Date*: 2018-09-11
    Sponsor Name:Aarhus University
    Full Title: The effect of lacosamide in peripheral neuropathic pain: a randomized, double-blind, placebo-controlled, phenotype-stratified study
    Medical condition: Peripheral Neuropathic pain
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004852 10077974 Peripheral neuropathic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-005506-32 Sponsor Protocol Number: Dulo2006 Start Date*: 2007-03-05
    Sponsor Name:Danish Pain Research Center
    Full Title: Pain, anxiety and depression in neuropathic and non-neuropathic pain: Effect of monoamine modulation.
    Medical condition: Chronic pain: neuropathic pain and fibromyalgia
    Disease: Version SOC Term Classification Code Term Level
    8.1 10033371 Pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2008-001501-42 Sponsor Protocol Number: 220668 Start Date*: 2008-05-15
    Sponsor Name:Jukka Sairanen
    Full Title: Tacrolimus in the treatment of Painful Bladder Syndrome / Interstitial Cystitis
    Medical condition: Painful bladder syndrome / interstitial cystitis (PBS/IC)
    Disease: Version SOC Term Classification Code Term Level
    1 10005063 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-011233-27 Sponsor Protocol Number: 09/WNo02/7 Start Date*: 2009-09-10
    Sponsor Name:North Wales NHS Trust
    Full Title: Comparison of efficacy of concentration with volume of local anaesthetics in femoral-sciatic blocks for total knee replacement
    Medical condition: No medical condition or disease under investigation.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10002182 Analgesia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2008-000239-17 Sponsor Protocol Number: 08-PP-03 Start Date*: 2008-05-06
    Sponsor Name:CHU de NICE
    Full Title: Use of MEOPA by elderly with dementia
    Medical condition: PAIN DUE TO BEDSORE OR WOUND BY ELDERLY WITH DEMENTIA
    Disease: Version SOC Term Classification Code Term Level
    9.1 10056350 Pain management LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-011458-16 Sponsor Protocol Number: N/A Start Date*: 2009-09-10
    Sponsor Name:North Wales NHS Trust
    Full Title: Comparison of efficacy and side effects of intrathecal fentanyl with intrathecal morphine
    Medical condition: Analgesia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10002182 Analgesia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2015-000944-41 Sponsor Protocol Number: FenS-FenD Start Date*: 2015-04-20
    Sponsor Name:FONDAZIONE IRCCS "ISTITUTO NAZIONALE DEI TUMORI"
    Full Title: A PILOT STUDY TO TEST THE FEASIBILITY OF A TWO-ARM, DOUBLE BLIND, PARALLEL-GROUP, RANDOMIZED CONTROLLED TRIAL FOR THE COMPARISON OF THE DURATION OF THE ANALGESIC EFFICACY OF A SINGLE MATRIX TRANSDE...
    Medical condition: Patients with oncological pain
    Disease: Version SOC Term Classification Code Term Level
    20.0 10018065 - General disorders and administration site conditions 10033371 Pain PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2022-000902-82 Sponsor Protocol Number: D8000-003 Start Date*: 2022-05-24
    Sponsor Name:Alzecure Pharma AB
    Full Title: A Phase 2a, randomised, double-blind, placebo-controlled crossover study to explore the effects of ACD440 in patients with peripheral neuropathic pain with sensory hypersensitivity
    Medical condition: Peripheral neuropathic pain with sensory hypersensitivity
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004852 10077974 Peripheral neuropathic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-003259-20 Sponsor Protocol Number: VenlaTrama_1.0 Start Date*: 2011-09-08
    Sponsor Name:University of Turku
    Full Title: Effect of duloxetine and venlafaxine on the pharmacokinetics and pharmacodynamics of oral tramadol: A three-phase randomized balanced cross-over study in healthy volunteers
    Medical condition: Acute postoperative pain and chronic pain syndromes
    Disease: Version SOC Term Classification Code Term Level
    14.0 10018065 - General disorders and administration site conditions 10066714 Acute pain LLT
    14.0 10018065 - General disorders and administration site conditions 10049475 Chronic pain LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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