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Clinical trials for Topical cream formulation

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44338   clinical trials with a EudraCT protocol, of which   7368   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    35 result(s) found for: Topical cream formulation. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2008-002317-40 Sponsor Protocol Number: 280210BS Start Date*: 2008-10-17
    Sponsor Name:Perrigo Israel Pharmaceuticals Ltd.
    Full Title: A phase IIa, multi-center, randomized, double-blind, vehicle-controlled study to determine antipsoriatic efficacy and safety of topical CEP-701 (lestaurtinib) cream formulations in patients with ps...
    Medical condition: Chronic plaque type psoriasis of mild to moderate severity, at least one plaque with a treatment area of approximately 25 - 50 cm2
    Disease: Version SOC Term Classification Code Term Level
    9.1 10050576 Psoriasis vulgaris LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-002112-26 Sponsor Protocol Number: 139B7 Start Date*: 2007-05-21
    Sponsor Name:YORK Pharma GmbH
    Full Title: Open, single-arm phase-III study to investigate the percutaneous absorption of abafungin after topical dermal application of Abafungin cream 1.0 % (YORK Pharma GmbH) in 20 patients with tinea pedis...
    Medical condition: Tinea pedis interdigital
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-007037-39 Sponsor Protocol Number: BF-37-CT-002 Start Date*: 2008-02-14
    Sponsor Name:Biofrontera Bioscience GmbH
    Full Title: A Phase II Proof-of-Concept, Randomized, Double-blind, Vehicle-controlled Study, Including an Open-label Comparison to an Active Control, To Assess the Efficacy and Safety/Tolerability of Topical R...
    Medical condition: Patients with stable plaque-type psoriasis with plaques of sufficient size of at least 2 cm in diameter for five comparable treatment areas
    Disease: Version SOC Term Classification Code Term Level
    9.1 10050576 Psoriasis vulgaris LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2022-001374-60 Sponsor Protocol Number: MOB-02 Start Date*: 2022-07-21
    Sponsor Name:BCN Peptides
    Full Title: A randomized, double blinded, placebo controlled clinical trial to evaluate the antipruritic efficacy of the topical application of PARENTIDE cream in histamine-induced itch in healthy volunteers
    Medical condition: Treatment of pruritus or uticaria
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-002141-24 Sponsor Protocol Number: H 527000 - 0805 Start Date*: 2008-05-26
    Sponsor Name:Almirall Hermal GmbH
    Full Title: A phase II, single-center, randomized, controlled, observer-blind study to determine the non-inferiority of a topical mometasone formulation vs a marketed comparator by evaluation of the anti-psori...
    Medical condition: volunteers with psoriasis vulgaris in a cronic stable phase and stable plaques with an area sufficient for 3 treatment fields
    Disease: Version SOC Term Classification Code Term Level
    9.1 10050576 Psoriasis vulgaris LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-007173-20 Sponsor Protocol Number: V00071CR202 Start Date*: 2009-02-19
    Sponsor Name:Pierre Fabre Dermatologie represented by Institut de Recherche Pierre Fabre
    Full Title: Assessment of the activity of a new cream containing betamethasone dipropionate at 0.010%, 0.025% and 0.050% versus reference products using a vasoconstriction assay in healthy subjects.
    Medical condition: Topical treatment of inflammatory dermatosis linked to cutaneous dryness
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2018-000685-12 Sponsor Protocol Number: MC2-01-C6 Start Date*: Information not available in EudraCT
    Sponsor Name:MC2 Therapeutics Ltd
    Full Title: A Multicentre, Open-label, Single-group Maximal Use Trial, Evaluating the Safety and Pharmacokinetic Profile of the Active Ingredients and their Metabolites after application of MC2-01 Cream in Ado...
    Medical condition: Extensive Psoriasis Vulgaris
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004858 10050576 Psoriasis vulgaris LLT
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) CZ (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2011-004610-42 Sponsor Protocol Number: QA351 Start Date*: 2012-01-24
    Sponsor Name:London School of Hygiene and Tropical Medicine
    Full Title: Evaluation of topical ibuprofen and steroid in the reduction of local reactions and symptoms from an Aedes aegypti mosquito bite
    Medical condition: Inflamatory reaction to a mosquito bite
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-021193-11 Sponsor Protocol Number: HT-07 Start Date*: 2010-09-14
    Sponsor Name:Helperby Thearapeutics Ltd
    Full Title: A randomised, open-labelled, multiple dose study of HT61 formulations applied to the anterior nares plus chlorhexidine body and hair washes in subjects with nasal carriage of Staphylococcus aureus
    Medical condition: Nasal carriage of Staphylococcus aureus (including MRSA)
    Disease: Version SOC Term Classification Code Term Level
    13 10067914 Staphylococcal colonisation LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-002842-20 Sponsor Protocol Number: 241012BS Start Date*: 2005-09-29
    Sponsor Name:York Pharma GmbH
    Full Title: Phase II dose ranging study to evaluate the anti-mycotic efficacy of topical Abafungin formulations in patients with tinea pedis.
    Medical condition: patients
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-009379-36 Sponsor Protocol Number: 281015BS Start Date*: 2009-04-17
    Sponsor Name:Marinomed Biotechnologie GmbH
    Full Title: A phase II, single-center, randomized, controlled, observer-blind study with intra-individual comparisons within two parallel groups to assess the efficacy of a topical Aescin formulation in the tr...
    Medical condition: subjects with proven nickel allergy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2012-000746-36 Sponsor Protocol Number: P-100797-01 Start Date*: 2012-03-28
    Sponsor Name:Ferrer Internacional, S.A.
    Full Title: A phase I open-label multiple dose study to examine the systemic bioavailability and safety of twice daily topical applications of ozenoxacin 1% cream formulation in patients with impetigo
    Medical condition: Impetigo
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10021531 Impetigo PT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: (No results available)
    EudraCT Number: 2012-002998-62 Sponsor Protocol Number: ROF-PSOR_104 Start Date*: 2012-12-13
    Sponsor Name:Takeda Pharma A/S
    Full Title: A Randomized, Single-Center, Observer-Blind, Vehicle- and Active Comparator-Controlled Phase 1b Study to Assess the Effect and Local Safety and Tolerability Of Roflumilast and BYK321084 – Phosphod...
    Medical condition: Mild to moderate, chronical, stable Psoriasis vulgaris
    Disease: Version SOC Term Classification Code Term Level
    15.1 10040785 - Skin and subcutaneous tissue disorders 10037153 Psoriasis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-005430-12 Sponsor Protocol Number: TPD103280 Start Date*: 2006-04-04
    Sponsor Name:GlaxoSmithKline Research & Development Limited
    Full Title: Randomised, double-blind, placebo-controlled study of topical GW842470X formulation in adult patients with moderate atopic dermatitis
    Medical condition: Atopic Dermatitis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-001263-32 Sponsor Protocol Number: 241011BS Start Date*: 2006-07-21
    Sponsor Name:York Pharma GmbH
    Full Title: Phase III study to evaluate the anti-mycotic efficacy of a topical Abafungin formulation in patients with tinea pedis
    Medical condition: Patients with tinea pedis interdigitalis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) DE (Completed) IS (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-002531-18 Sponsor Protocol Number: 69HCL16_0062 Start Date*: 2018-10-31
    Sponsor Name:Hospices Civils de Lyon
    Full Title: Topical Everolimus versus placebo for the treatment of facial angiofibromas in patients with tuberous sclerosis complex. A phase II/III, multicentre, randomized, double-blind, placebo-controlled st...
    Medical condition: angiofibromas
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10002429 Angiofibroma PT
    Population Age: Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-021207-25 Sponsor Protocol Number: CT327PV0109 Start Date*: 2010-08-23
    Sponsor Name:Creabilis Sàrl
    Full Title: CT 327 in the treatment of psoriasis vulgaris: A Randomized, Double-Blind, Placebo Controlled Phase II, Multi-Centre, Study of the Efficacy and Safety of CT 327, a topical cream formulation of Pegy...
    Medical condition: Psoriasis Vulgaris
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2013-003501-25 Sponsor Protocol Number: ECM2013 Start Date*: 2014-02-20
    Sponsor Name:Mesoestetic Pharma group S.L.
    Full Title: Efficacy and safety of a 4% hydroquinone cream (Melanoderm 4%) for the treatment of melasma: a randomized controlled split-face study.
    Medical condition: Facial melasma
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004858 10027161 Melasma LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-000182-38 Sponsor Protocol Number: ACYCLOVIR LP 01/06 Start Date*: 2007-07-26
    Sponsor Name:MIPHARM
    Full Title: EFFICACY AND SAFETY OF A NEW TOPICAL FORMULATION OF ACYCLOVIR GEL (LP) IN THE TREATMENT OF HERPES SIMPLEX LABIALIS A RANDOMIZED, Single-BLIND, MULTICENTER, CONTROLLED CLINICAL TRIAL ve...
    Medical condition: Subjects with a clinical diagnosis of Herpes Simplex Labialis on the perioral area.
    Disease: Version SOC Term Classification Code Term Level
    6.1 10019948 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended) GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-005344-83 Sponsor Protocol Number: PBD-0313 Start Date*: 2007-02-09
    Sponsor Name:Probiodrug AG
    Full Title: A Randomized, Double-blind, Placebo and Active Treatment-Controlled Study in Psoriatic Patients to Assess the Tolerability, Pharmacokinetics and Efficacy of a Cream Formulation Containing 3% of P32/98
    Medical condition: Psoriasis is a common inherited autoimmune disease that affects 2-3% of the world-wide population. There are several recognized forms of psoriasis, such as plaque psoriasis, which is also known as ...
    Disease: Version SOC Term Classification Code Term Level
    8.1 10037153 Psoriasis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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