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Clinical trials for Type I Diabetes Mellitus

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   43925   clinical trials with a EudraCT protocol, of which   7306   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    455 result(s) found for: Type I Diabetes Mellitus. Displaying page 1 of 23.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2009-011672-29 Sponsor Protocol Number: NN1250-3585 Start Date*: 2009-11-25
    Sponsor Name:Novo Nordisk A/S
    Full Title: A trial investigating the efficacy and safety of NN1250 compared to insulin detemir in subjects with type 1 diabetes mellitus in a basal/bolus treatment regimen
    Medical condition: type 1 diabetes mellitus
    Disease: Version SOC Term Classification Code Term Level
    12.0 10045228 Type I diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) IT (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-012317-22 Sponsor Protocol Number: PBBT Start Date*: 2009-12-04
    Sponsor Name:AZIENDA OSPEDALIERO UNIVERSITARIA OSPEDALI RIUNITI UMBERTO I - G.M.LANCISI - G.SALESI
    Full Title: PEDIATRIC BASAL BOLUS THERAPY - Basal-Bolus regimen in the treatment of children with type 1 diabetes
    Medical condition: pre-puberal children with T1DM
    Disease: Version SOC Term Classification Code Term Level
    9.1 10023253 LLT
    9.1 10021211 LLT
    9.1 10045238 LLT
    9.1 10045228 LLT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-001291-19 Sponsor Protocol Number: BC3-CT-002 Start Date*: 2011-05-20
    Sponsor Name:Adocia SA
    Full Title: A phase IIa, double-blinded, randomized trial comparing the pharmacokinetics, pharmacodynamics and safety of BioChaperone® rhInsulin to fast-acting insulin analog in patients with Type 1 Diabetes m...
    Medical condition: Diabetes mellitus
    Disease: Version SOC Term Classification Code Term Level
    13.1 10027433 - Metabolism and nutrition disorders 10045228 Type I diabetes mellitus LLT
    13.1 10027433 - Metabolism and nutrition disorders 10012608 Diabetes mellitus insulin-dependent LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-001039-72 Sponsor Protocol Number: RP06 Start Date*: 2008-03-06
    Sponsor Name:Cambridge University Hospitals NHS Foundation Trust, jointly with University of Cambridge
    Full Title: Adolescent Type 1 Diabetes Cardio-Renal Intervention Trial
    Medical condition: Type 1 diabetes in adolescents
    Disease: Version SOC Term Classification Code Term Level
    14.0 10027433 - Metabolism and nutrition disorders 10012609 Diabetes mellitus juvenile onset LLT
    14.0 10027433 - Metabolism and nutrition disorders 10012608 Diabetes mellitus insulin-dependent LLT
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2017-001227-45 Sponsor Protocol Number: PHT/2017/20 Start Date*: 2017-06-12
    Sponsor Name:Portsmouth Hospitals NHS Trust
    Full Title: Comparison of ambulatory glucose profile prior to and during pancreatic enzyme replacement therapy in patients with diabetes and pancreatic exocrine insufficiency: a single-arm phase IV trial
    Medical condition: Type 1 diabetes and type 2 diabetes mellitus Pancreatic exocrine insufficiency
    Disease: Version SOC Term Classification Code Term Level
    20.0 10027433 - Metabolism and nutrition disorders 10067585 Type 2 diabetes mellitus PT
    20.1 10027433 - Metabolism and nutrition disorders 10045228 Type I diabetes mellitus LLT
    20.0 100000004856 10033628 Pancreatic insufficiency LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-002949-35 Sponsor Protocol Number: NN1250-1988 Start Date*: 2011-11-01
    Sponsor Name:Novo Nordisk A/S
    Full Title: This trial is a randomized, single-centre, double-blind, two-period cross-over glucose clamp trial to test for bioequivalence between two SIBA (IDeg) formulations in healthy subjects. This trial...
    Medical condition: Healthy volunteers (Diabetes Mellitus, Type 1 and Diabetes Mellitus, Type 2)
    Disease: Version SOC Term Classification Code Term Level
    14.0 10027433 - Metabolism and nutrition disorders 10045228 Type I diabetes mellitus LLT
    14.0 10027433 - Metabolism and nutrition disorders 10045242 Type II diabetes mellitus LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2012-000619-10 Sponsor Protocol Number: RUNMC-EX-BCM-2012 Start Date*: 2012-07-24
    Sponsor Name:Radboud University Nijmegen Medical Centre
    Full Title: Clinical proof-of-principle of the determination of the beta cell mass in vivo by SPECT imaging with the 111In-labeled GLP-1 analogue DTPA-[K40]-Exendin 4
    Medical condition: patients with long-standing type 1 diabetes
    Disease: Version SOC Term Classification Code Term Level
    14.1 10014698 - Endocrine disorders 10018424 Glucose metabolism disorders (incl diabetes mellitus) HLGT
    14.1 10014698 - Endocrine disorders 10012602 Diabetes mellitus (incl subtypes) HLT
    14.1 10027433 - Metabolism and nutrition disorders 10012601 Diabetes mellitus PT
    14.1 10027433 - Metabolism and nutrition disorders 10067584 Type 1 diabetes mellitus PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-001047-36 Sponsor Protocol Number: NN1218-4131 Start Date*: 2015-11-04
    Sponsor Name:Novo Nordisk A/S
    Full Title: Efficacy and Safety of Faster-acting Insulin Aspart compared to NovoRapid® both in combination with Insulin Degludec in Adults with Type 1 Diabetes
    Medical condition: Diabetes Mellitus, Type 1
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004861 10045228 Type I diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BG (Completed) DE (Completed) AT (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2010-022513-26 Sponsor Protocol Number: SKY1052-2-001 Start Date*: 2011-02-22
    Sponsor Name:SkyePharma AG
    Full Title: Randomised, single-blind, placebo controlled, four-period four-treatment cross-over design, proof of concept study to compare the pharmacodynamic, safety and pharmacokinetics of one single administ...
    Medical condition: Type 1 Diabetes Mellitus
    Disease: Version SOC Term Classification Code Term Level
    12.1 10012601 Diabetes mellitus LLT
    12.1 10012608 Diabetes mellitus insulin-dependent LLT
    12.1 10012610 Diabetes mellitus loss of control LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2010-021057-39 Sponsor Protocol Number: NN2211-1800 Start Date*: 2010-11-11
    Sponsor Name:Novo Nordisk A/S
    Full Title: A Randomized, Double-blind, Placebo Controlled Trial to Assess Safety/Tolerability, Pharmacokinetics & Pharmacodynamics of Liraglutide in Paediatric (10 – 17 years old) Subjects with Type 2 Diabetes
    Medical condition: Type 2 Diabetes
    Disease: Version SOC Term Classification Code Term Level
    14.1 10027433 - Metabolism and nutrition disorders 10067585 Type 2 diabetes mellitus PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed) SI (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2007-005899-13 Sponsor Protocol Number: GEN-084-OL Start Date*: 2008-06-24
    Sponsor Name:Generex Biotechnology Corp.
    Full Title: A 26-Week, Open-Label, Randomized, Active Comparator Study of Generex Oral-lyn™ Spray and Injected Human Insulin In Subjects With Type-1 Diabetes Mellitus
    Medical condition: type 1 diabetes mellitus
    Disease: Version SOC Term Classification Code Term Level
    9.1 10045228 Type I diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BG (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-003122-27 Sponsor Protocol Number: 767/11 Start Date*: 2011-11-01
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: Assessment of aspirin response in patients with Type 1 diabetes mellitus: a pilot study
    Medical condition: type 1 diabetes
    Disease: Version SOC Term Classification Code Term Level
    14.1 10027433 - Metabolism and nutrition disorders 10045228 Type I diabetes mellitus LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-003144-12 Sponsor Protocol Number: DBC-14LIPOINJ01 Start Date*: 2014-09-15
    Sponsor Name:Profil Institut für Stoffwechselforschung GmbH
    Full Title: A trial to compare the pharmacokinetics and pharmacodynamics of insulin lispro administered s.c. into lipohypertrophic or normal abdominal adipose tissue in subjects with diabetes mellitus type 1
    Medical condition: Diabetes mellitus
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004861 10045228 Type I diabetes mellitus LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-015398-11 Sponsor Protocol Number: PKPD_SQ_1 Start Date*: 2009-11-03
    Sponsor Name:Radboud University Nijmegen Medical Centre
    Full Title: Pharmacokinetic and pharmacodynamic profile of rapid-acting insulin injected by needle-free jet-injection
    Medical condition: type 1 diabetes mellitus
    Disease: Version SOC Term Classification Code Term Level
    12.0 10045228 Type I diabetes mellitus LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2011-002104-32 Sponsor Protocol Number: NN1218-3888 Start Date*: 2014-11-14
    Sponsor Name:Novo Nordisk A/S
    Full Title: A trial investigating the pharmacokinetic properties of FIAsp in children, adolescents and adults with type 1 diabetes
    Medical condition: Diabetes Mellitus, Type 1
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004861 10045228 Type I diabetes mellitus LLT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-008306-43 Sponsor Protocol Number: NN1250-1995 Start Date*: Information not available in EudraCT
    Sponsor Name:Novo Nordisk A/S
    Full Title: A Trial Investigating the Pharmacokinetic Properties of NN1250 in Children, Adolescents and Adults with Type 1 Diabetes
    Medical condition: Type I diabetes mellitus
    Disease: Version SOC Term Classification Code Term Level
    12.0 10045228 Type I diabetes mellitus LLT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2014-002267-15 Sponsor Protocol Number: GluST1_vers4_2014 Start Date*: 2014-07-31
    Sponsor Name:Hvidovre Hospital
    Full Title: Treatment of hypoglycemia with glucagon among patients with type 1 diabetes mellitus
    Medical condition: Patients with type 1 diabetes mellitus
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004861 10012608 Diabetes mellitus insulin-dependent LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-000322-11 Sponsor Protocol Number: HEPPI-02 Start Date*: 2015-03-23
    Sponsor Name:Medizinische Universität Graz; Universitätsklinik für Innere Medizin; Abteilung für Endokrinologie und Stoffwechsel
    Full Title: Assessment of the Duration of Glucagon’s Waning Effect on the Hepatic Glucose Production in Type 1 Diabetes Patients
    Medical condition: Diabetes mellitus type 1
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004861 10012608 Diabetes mellitus insulin-dependent LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-000949-77 Sponsor Protocol Number: BC3-CT008 Start Date*: 2014-05-12
    Sponsor Name:Adocia
    Full Title: A double-blinded, randomised, four -period crossover euglycemic clamp trial investigating the dose-response and dose-exposure relationship of BC222 insulin lispro in three different doses in subje...
    Medical condition: Diabetes mellitus type 1
    Disease: Version SOC Term Classification Code Term Level
    16.1 10027433 - Metabolism and nutrition disorders 10067584 Type 1 diabetes mellitus PT
    Population Age: Adults Gender: Male
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2017-002014-31 Sponsor Protocol Number: NN1218-4371 Start Date*: 2017-10-26
    Sponsor Name:Novo Nordisk A/S
    Full Title: A trial comparing the pharmacokinetic properties of fast-acting insulin aspart between children, adolescents and adults with type 1 diabetes
    Medical condition: Diabetes Mellitus, Type 1
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004861 10045228 Type I diabetes mellitus LLT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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