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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44379   clinical trials with a EudraCT protocol, of which   7391   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Study title: AN 04949071 Medline 20070101. TI (Stimulation of the appetite in children: comparison between the action of cyproheptadine and a placebo). TT Stimulation de l'appetit chez l'enfant: comparaison entre l'action de la cyproheptadine et d'un placebo. SO Revue medicale de la Suisse romande, {Rev-Med-Suisse-Romande}, Aug 1971, vol. 91, no. 8, p. 567-72, ISSN: 0035-3655. AU Juillard-E. YR 1971.AN 04949071 Medline 20070101. TI (Stimulation of the appetite in children: comparison between the action of cyproheptadine and a placebo). TT Stimulation de l'appetit chez l'enfant: comparaison entre l'action de la cyproheptadine et d'un placebo. SO Revue medicale de la Suisse romande, {Rev-Med-Suisse-Romande}, Aug 1971, vol. 91, no. 8, p. 567-72, ISSN: 0035-3655. AU Juillard-E. YR 1971.

    Type of medicine: Medicines containing chemical active substances
    Therapeutic area: Pathological Conditions, Signs and Symptoms [C23]  
    Brands: Please see report, Please see report
    MAH holders: Please see report
    Assessment:
    Active substance: CYPROHEPTADINE
    ATC code:
    Document link:
    Document date:
    Study number:
    EudraCT number:
    Scope of study: Clinical
    Population of study subjects: Preterm newborn Infants Newborn infants (1 to 27 days) Infants and toddlers (28 days to 24 months) Children (2 to 11 years) Adolescents (12 to 18 years)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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