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Clinical trials for Cancer

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44349   clinical trials with a EudraCT protocol, of which   7376   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    10,212 result(s) found for: Cancer. Displaying page 201 of 511.
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    EudraCT Number: 2009-011377-33 Sponsor Protocol Number: 08_CLPHA_55 Start Date*: 2009-06-25
    Sponsor Name:The Christie NHS Foundation Trust
    Full Title: AN ASSESSMENT OF IMAGING AND CIRCULATING BIOMARKERS IN PATIENTS WITH METASTATIC COLORECTAL CARCINOMA TREATED WITH THE ANTI-VEGF MONOCLONAL ANTIBODY BEVACIZUMAB
    Medical condition: Metastatic colorectal cancer
    Disease: Version SOC Term Classification Code Term Level
    14.0 10042613 - Surgical and medical procedures 10056417 Monoclonal antibody unconjugated therapy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-002385-20 Sponsor Protocol Number: CAO/ARO/AIO-04 Start Date*: 2006-06-28
    Sponsor Name:Strahlenklinik, Universitätsklinikum Erlangen, insoweit handelnd für den Freistaat Bayern
    Full Title: Prospective randomised multicenter phase-III-study: Preoperative radiochemotherapy and adjuvant chemotherapy with 5-Fluorouracil plus oxaliplatin versus preoperative radiochemotherapy and adjuvant...
    Medical condition: Male or femal patients suffering from histologically proven carcinoma of the rectum (tumor ≤ 12cm from the anal verge, with clinically staged T3/4 or any node-positive disease
    Disease: Version SOC Term Classification Code Term Level
    8.1 10038039 Rectal neoplasms malignant HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-003785-33 Sponsor Protocol Number: 20060100 Start Date*: 2006-12-05
    Sponsor Name:Amgen Inc
    Full Title: A Global, Multicenter, Open-label, Single Agent, Two-stage Phase 2 Study to Evaluate the Efficacy and Safety of AMG 102 in Subjects With Advanced Renal Cell Carcinoma
    Medical condition: Advanced Renal Cell Carcinoma
    Disease: Version SOC Term Classification Code Term Level
    8.1 10050513 Metastatic renal cell carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2007-003323-20 Sponsor Protocol Number: CP4055-204 Start Date*: 2008-05-30
    Sponsor Name:Clavis Pharma ASA
    Full Title: A Phase I/II Study of CP-4055 in Patients with Platinum Resistant Ovarian Cancer
    Medical condition: A phase I/II clinical study of CP4055 in patients with platinum resistant ovarian cancer
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-006072-38 Sponsor Protocol Number: HEPATICA Start Date*: 2007-11-07
    Sponsor Name:the Dutch Colorectal Cancer Group
    Full Title: A Randomised Two Arm Phase III Study in Patients Post Radical Resection of Liver Metastasis of Colorectal Cancer to Investigate Bevacizumab (q3w) in Combination With Capecitabine Plus Elaoxantin (X...
    Medical condition: Liver metastatis of colorectal cancer.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2010-020621-40 Sponsor Protocol Number: OCTO_021 Start Date*: 2010-09-30
    Sponsor Name:The University of Oxford
    Full Title: SONATINA: A Phase II Multi-Centre Randomised Controlled Study of Nelfinavir Addition to Radiotherapy Treatment in Neo-Adjuvant Therapy for Rectal Cancer
    Medical condition: inoperable rectal cancer
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-004683-30 Sponsor Protocol Number: KRAS2011 Start Date*: 2012-05-02
    Sponsor Name:VU University Medical
    Full Title: A phase II study of sorafenib and metformin in patients with locally advanced and/or metastatic non-smal cell lung cancer (NSCLC) with a K-Ras mutation
    Medical condition: Patients with advanced non small cell lung cancer that harbours a K-Ras mutation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-006295-29 Sponsor Protocol Number: ICR-CTSU/2008/10019 Start Date*: 2009-08-20
    Sponsor Name:The Institute of Cancer Research [...]
    1. The Institute of Cancer Research
    2. University Hospital Birmingham NHS Foundation Trust
    Full Title: A single group trial evaluating one cycle of adjuvant BEP chemotherapy in high risk, stage 1 non-seminomatous germ cell tumours of the testis (NSGCTT)
    Medical condition: Patients with newly diagnosed NSGCTT or mixed GCT (MGCT) with vascular invasion and stage 1 disease
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10029557 Non-seminoma testicular cancer LLT
    Population Age: Adolescents, Under 18, Adults Gender: Male
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2008-007652-10 Sponsor Protocol Number: BRD 08/11-A Start Date*: 2009-04-06
    Sponsor Name:Centre René Gauducheau
    Full Title: Etude de phase II ouverte évaluant en fonction du polymorphisme du CYP2D6, le taux de réponse biologique au traitement par tamoxifène (TAM) administré en situation pré-opératoire chez des patientes...
    Medical condition: Cancer du sein
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-005289-31 Sponsor Protocol Number: LF-PB/14/05 Start Date*: 2015-08-04
    Sponsor Name:CHEMI S.P.A.
    Full Title: A multicentre, double blind, randomized placebo controlled trial to assess the effect of LF-PB on seroma formation in women with breast cancer undergoing Axillary Lymph Node Dissection
    Medical condition: Woman with Breast Cancer Undergoing Axillary Lymph Node Dissection
    Disease: Version SOC Term Classification Code Term Level
    20.0 10005329 - Blood and lymphatic system disorders 10005329 Blood and lymphatic system disorders SOC
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2017-004509-42 Sponsor Protocol Number: CTL-101-023 Start Date*: 2018-04-23
    Sponsor Name:Celleron Therapeutics Ltd
    Full Title: A Phase Ib/ II Trial to Assess the Safety and Efficacy of CXD101 in Combination with the PD-1 Inhibitor Nivolumab in Patients with Metastatic, Previously-Treated, Microsatellite-Stable Colorectal C...
    Medical condition: Metastatic, Previously-Treated, Microsatellite-Stable Colorectal Carcinoma
    Disease: Version SOC Term Classification Code Term Level
    21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10061451 Colorectal cancer PT
    21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10052358 Colorectal cancer metastatic PT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10010036 Colorectal carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2008-006051-40 Sponsor Protocol Number: Beva2007 Start Date*: 2008-09-09
    Sponsor Name:AZIENDA OSPEDALIERA SENESE
    Full Title: A PHASE II STUDY: UNOPERABLE NON NON SQUAMOUS NON SMALL CELL LUNG CANCER METRONOMIC BIOCHEMOTHERAPY WITH WEEKLY CISPLATIN, DAILY ORAL ETOPOSIDE AND BEVACIZUMAB (mPEBev regimen)
    Medical condition: Patients with UNOPERABLE NON NON SQUAMOUS NON SMALL CELL LUNG CANCER
    Disease: Version SOC Term Classification Code Term Level
    9.1 10001160 Adenocarcinoma lung LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-018324-13 Sponsor Protocol Number: CRLOT/01 Start Date*: 2011-11-09
    Sponsor Name:CONSORZIO PER LA RICERCA ONCOLOGICA
    Full Title: Open phase II randomized study to assess safety, tolerability and efficacy of trastuzumab combined with vinorelbine in patients with HER2 positive metastatic breast cancer and cardiac diseases
    Medical condition: HER2 positive breast cancer
    Disease: Version SOC Term Classification Code Term Level
    9.1 10038604 SOC
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2004-005215-29 Sponsor Protocol Number: 03-CoFactor Start Date*: 2005-06-03
    Sponsor Name:ADVENTRX Pharmaceuticals Inc
    Full Title: A Multi-Center, Open Label, Parallel Group, Randomised, Phase IIB Clinical Trial to Evaluate the Safety and Efficacy of CoFactor and 5-FU versus Leucovorin and 5-FU in Subjects with Metastatic Colo...
    Medical condition: Metastatic Colorectal Carcinoma
    Disease: Version SOC Term Classification Code Term Level
    7.1 10052358 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-000686-19 Sponsor Protocol Number: MO05/6844 Start Date*: 2005-04-28
    Sponsor Name:University of Leeds
    Full Title: PACT (Patient Preferences in Adjuvant Colorectal Cancer Therapy) - A randomised crossover clinical trial comparing Bolus Fluorouracil/Leucovorin to Capecitabine as treatment for moderate to high ri...
    Medical condition: Moderate to high risk resected colorectal cancer
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-009461-33 Sponsor Protocol Number: AV-IT-001 Start Date*: 2009-06-04
    Sponsor Name:AISAR ASSOCIAZIONE ITALIANA PER LO STUDIO DEGLI ANTIMICROBICI E DELLE RESISTENZE
    Full Title: A Phase IIa, Open-Label, Dose-Escalating Study to Evaluate the Safety of AV-951 in Combination with Everolimus in Subjects with Metastatic Renal Cell Carcinoma
    Medical condition: Metastatic Renal Cell Carcinoma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10050513 Metastatic renal cell carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-009194-99 Sponsor Protocol Number: 2008002 Start Date*: 2009-07-15
    Sponsor Name:Agensys Inc
    Full Title: A Global, Multi-center, Open-label, Phase 2 Study of AGS-1C4D4 Given in Combination With Gemcitabine in Subjects with Metastatic Pancreatic Cancer ?Estudio global, multicéntrico, abierto, de fase ...
    Medical condition: Metastatic Pancreatic Cancer. To evaluate AGS-1C4D4 administered in combination with gemcitabine as measured by the survival rate at 6 months post-randomization Cancer de páncreas metástasico. Eva...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-003478-29 Sponsor Protocol Number: VIDAFACT Start Date*: 2014-03-21
    Sponsor Name:Maria Nabal Vicuña (Paliative Care Supportive Team-Hospital Universitari Arnau de Vilanova de Lleida)
    Full Title: The effect on quality of life of Vitamin D administration for advanced cancer treatment. A randomized controlled trial
    Medical condition: The effect on quality of life of Vitamin D administration for advanced cancer treatment. A randomized controlled trial
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-003760-47 Sponsor Protocol Number: 2018-14 Start Date*: 2020-04-06
    Sponsor Name:Assistance Publique Hôpitaux de Marseille
    Full Title: Evaluation of 68Ga-PSMA PET-CT in the initial extension assessment of advanced renal cell carcinoma a prospective, multicenter, open study
    Medical condition: renal cell cancer (RCC)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-005605-36 Sponsor Protocol Number: SCI-Ta1-NSCLC-CHEMOP2-001 Start Date*: 2016-07-07
    Sponsor Name:SCICLONE PHARMACEUTICALS ITALY S.R.L.
    Full Title: Thymosin alpha 1 plus maintenance therapy with the Standard of Care (SoC) chemotherapy plus cisplatin (or carboplatin) in patients with metastatic Non-Small Cell Lung Cancer (NSCLC), EGFR wild type
    Medical condition: metastatic Non-Small Cell Lung Cancer (NSCLC), EGFR wild type
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004864 10064049 Lung adenocarcinoma metastatic LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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